DK102479A - Fremgangsmaade til fremstilling af 1,2-og 1,3-(di-o-n-alkyl) glycerolderivater - Google Patents

Fremgangsmaade til fremstilling af 1,2-og 1,3-(di-o-n-alkyl) glycerolderivater

Info

Publication number: DK102479A
Authority: DK; Denmark
Prior art keywords: alkyl; procedure; preparation; glycerol derivatives; glycerol
Prior art date: 1978-05-15

Application number

DK102479A

Other languages

English (en)

Other versions

DK149946C (da

DK149946B (da

Inventor

A R Kraska

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-15

Filing date

1979-03-12

Publication date

1979-11-16

1979-03-12 Application filed by Pfizer filed Critical Pfizer

1979-11-16 Publication of DK102479A publication Critical patent/DK102479A/da

1986-11-03 Publication of DK149946B publication Critical patent/DK149946B/da

1987-06-15 Application granted granted Critical

1987-06-15 Publication of DK149946C publication Critical patent/DK149946C/da

Links

PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical class OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK102479A 1978-05-15 1979-03-12 Analogifremgangsmaade til fremstilling af piperidin-derivater af 1,2- eller 1,3-(di-o-n-alkyl)propandiol eller farmaceutisk acceptable syreadditionssalte deraf DK149946C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90626078		1978-05-15
US05/906,260 US4173641A (en)	1978-05-15	1978-05-15	Di-O-n-alkyl glycerol derivatives as immune stimulants

Publications (3)

Publication Number	Publication Date
DK102479A true DK102479A (da)	1979-11-16
DK149946B DK149946B (da)	1986-11-03
DK149946C DK149946C (da)	1987-06-15

Family

ID=25422164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK102479A DK149946C (da)	1978-05-15	1979-03-12	Analogifremgangsmaade til fremstilling af piperidin-derivater af 1,2- eller 1,3-(di-o-n-alkyl)propandiol eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (38)

Country	Link
US (1)	US4173641A (da)
JP (2)	JPS5924974B2 (da)
AR (1)	AR221724A1 (da)
AT (1)	AT372678B (da)
AU (1)	AU513771B2 (da)
BE (1)	BE876229A (da)
CA (1)	CA1105935A (da)
CH (1)	CH639939A5 (da)
DD (1)	DD144540A5 (da)
DE (1)	DE2919514C2 (da)
DK (1)	DK149946C (da)
EG (1)	EG15252A (da)
ES (1)	ES480565A1 (da)
FI (1)	FI69450C (da)
FR (1)	FR2426039A1 (da)
GB (1)	GB2021580B (da)
GR (1)	GR72419B (da)
GT (1)	GT197957869A (da)
HK (1)	HK13584A (da)
HU (1)	HU180283B (da)
IE (1)	IE48229B1 (da)
IL (1)	IL57268A (da)
IN (1)	IN150574B (da)
IT (1)	IT1115217B (da)
KE (1)	KE3354A (da)
LU (1)	LU81253A1 (da)
MY (1)	MY8500096A (da)
NL (1)	NL175524C (da)
NO (1)	NO151285C (da)
NZ (1)	NZ190444A (da)
PH (1)	PH15256A (da)
PL (1)	PL123910B1 (da)
PT (1)	PT69607A (da)
SE (1)	SE429966B (da)
SG (1)	SG65483G (da)
SU (1)	SU1122220A3 (da)
YU (1)	YU41156B (da)
ZA (1)	ZA792306B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4255426A (en) *	1979-07-09	1981-03-10	Pfizer Inc.	1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
US4312877A (en) *	1979-07-09	1982-01-26	Pfizer Inc.	1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted piperidines, pharmaceutical compositions, thereof and use thereof
US4395394A (en) *	1979-10-26	1983-07-26	Pfizer Inc.	Use of lipid amines formulated with fat or lipid emulsions as vaccine adjuvants
US4310550A (en) *	1979-10-26	1982-01-12	Pfizer Inc.	Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants
JPS60105650A (ja) *	1983-11-14	1985-06-11	Ono Pharmaceut Co Ltd	グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
US4880626A (en) *	1985-01-18	1989-11-14	Mcmichael John	Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome
JPS62156230A (ja) *	1985-12-27	1987-07-11	Nippon Steel Corp	帯状物の蛇行修正方法
US4842862A (en) *	1986-07-03	1989-06-27	International Minerals & Chemical Corp.	Immunostimulating agents
ZA899436B (en) *	1988-12-12	1990-08-29	Ciba Geigy	Piperidine derivatives
WO2005077963A1 (fr) *	2004-01-16	2005-08-25	Institut Superieur Agricole De Beauvais	DErivEs de saccharides et d'itols possEdant un groupement O-alkyle ou un groupement O-alkyle et un groupement O-n-butanoyle. Applications comme mEdicaments dans les pathologies prolifEratives tumorales ou bEnignes.
WO2011076807A2 (en) *	2009-12-23	2011-06-30	Novartis Ag	Lipids, lipid compositions, and methods of using them

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2738351A (en) *	1952-08-02	1956-03-13	Bristol Lab Inc	Substituted glycerol ethers
US3432602A (en) *	1967-12-20	1969-03-11	Astra Ab	Oral alkyl glycerol ether improvement in radiation,radiomimetic,or cytostatic tumor therapies
US3943173A (en) *	1972-11-22	1976-03-09	Smithkline Corporation	3-Alkylamino- alpha-aminomethyl-4-hydroxybenzyl alcohols
US4012528A (en) *	1974-06-03	1977-03-15	Smithkline Corporation	α-AMINOALKYL-3-(1,2-DIHYDROXYETHYL)-4-HYDROXY-BENZYL ALCOHOLS HAVING β-ADRENERGIC STIMULANT ACTIVITY
US4069223A (en) *	1977-05-02	1978-01-17	G. D. Searle & Co.	4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof
US4166132A (en) *	1977-08-18	1979-08-28	Pfizer Inc.	Antiviral amine derivatives of glycerol and propanediols

1978
- 1978-05-15 US US05/906,260 patent/US4173641A/en not_active Expired - Lifetime
1979
- 1979-03-12 DK DK102479A patent/DK149946C/da not_active IP Right Cessation
- 1979-03-13 IN IN173/DEL/79A patent/IN150574B/en unknown
- 1979-04-18 PH PH22379A patent/PH15256A/en unknown
- 1979-04-26 CH CH395479A patent/CH639939A5/fr not_active IP Right Cessation
- 1979-05-10 YU YU1094/79A patent/YU41156B/xx unknown
- 1979-05-11 CA CA327,431A patent/CA1105935A/en not_active Expired
- 1979-05-11 AU AU47016/79A patent/AU513771B2/en not_active Ceased
- 1979-05-14 FR FR7912175A patent/FR2426039A1/fr active Granted
- 1979-05-14 PL PL1979215573A patent/PL123910B1/pl unknown
- 1979-05-14 IL IL57268A patent/IL57268A/xx unknown
- 1979-05-14 GT GT197957869A patent/GT197957869A/es unknown
- 1979-05-14 NZ NZ190444A patent/NZ190444A/xx unknown
- 1979-05-14 ES ES79480565A patent/ES480565A1/es not_active Expired
- 1979-05-14 IT IT22664/79A patent/IT1115217B/it active
- 1979-05-14 HU HU79PI677A patent/HU180283B/hu not_active IP Right Cessation
- 1979-05-14 SU SU792764751A patent/SU1122220A3/ru active
- 1979-05-14 AT AT0356179A patent/AT372678B/de not_active IP Right Cessation
- 1979-05-14 BE BE0/195142A patent/BE876229A/xx not_active IP Right Cessation
- 1979-05-14 GB GB7916722A patent/GB2021580B/en not_active Expired
- 1979-05-14 NL NLAANVRAGE7903769,A patent/NL175524C/xx active Search and Examination
- 1979-05-14 PT PT69607A patent/PT69607A/pt unknown
- 1979-05-14 JP JP54059019A patent/JPS5924974B2/ja not_active Expired
- 1979-05-14 GR GR59080A patent/GR72419B/el unknown
- 1979-05-14 SE SE7904216A patent/SE429966B/sv not_active IP Right Cessation
- 1979-05-14 FI FI791531A patent/FI69450C/fi not_active IP Right Cessation
- 1979-05-14 ZA ZA792306A patent/ZA792306B/xx unknown
- 1979-05-14 LU LU81253A patent/LU81253A1/xx unknown
- 1979-05-14 NO NO791604A patent/NO151285C/no unknown
- 1979-05-15 DE DE2919514A patent/DE2919514C2/de not_active Expired
- 1979-05-15 DD DD79212895A patent/DD144540A5/de unknown
- 1979-05-15 EG EG289/79A patent/EG15252A/xx active
- 1979-05-15 AR AR276517A patent/AR221724A1/es active
- 1979-08-08 IE IE938/79A patent/IE48229B1/en not_active IP Right Cessation
1982
- 1982-12-29 JP JP57235061A patent/JPS58131947A/ja active Granted
1983
- 1983-11-02 SG SG654/83A patent/SG65483G/en unknown
- 1983-11-22 KE KE3354A patent/KE3354A/xx unknown
1984
- 1984-02-16 HK HK135/84A patent/HK13584A/xx unknown
1985
- 1985-12-30 MY MY96/85A patent/MY8500096A/xx unknown

Also Published As

Publication number	Publication date
NO151285B (no)	1984-12-03
JPS55378A (en)	1980-01-05
ZA792306B (en)	1980-05-28
JPS58131947A (ja)	1983-08-06
SE7904216L (sv)	1979-11-16
YU41156B (en)	1986-12-31
CH639939A5 (fr)	1983-12-15
PH15256A (en)	1982-11-02
JPS6139301B2 (da)	1986-09-03
GT197957869A (es)	1980-11-04
PL123910B1 (en)	1982-12-31
FR2426039A1 (fr)	1979-12-14
GB2021580B (en)	1982-09-08
SE429966B (sv)	1983-10-10
FI69450C (fi)	1986-02-10
LU81253A1 (fr)	1979-12-07
FI791531A7 (fi)	1979-11-16
GR72419B (da)	1983-11-03
CA1105935A (en)	1981-07-28
AT372678B (de)	1983-11-10
HK13584A (en)	1984-02-24
FI69450B (fi)	1985-10-31
AU513771B2 (en)	1980-12-18
ATA356179A (de)	1983-03-15
IN150574B (da)	1982-11-13
DK149946C (da)	1987-06-15
SU1122220A3 (ru)	1984-10-30
NZ190444A (en)	1981-05-29
DE2919514C2 (de)	1982-06-03
IL57268A0 (en)	1979-09-30
YU109479A (en)	1983-02-28
IL57268A (en)	1982-05-31
IT7922664A0 (it)	1979-05-14
NO151285C (no)	1985-03-13
BE876229A (fr)	1979-11-14
KE3354A (en)	1983-12-16
GB2021580A (en)	1979-12-05
IT1115217B (it)	1986-02-03
AR221724A1 (es)	1981-03-13
PL215573A1 (da)	1980-07-01
JPS5924974B2 (ja)	1984-06-13
DK149946B (da)	1986-11-03
FR2426039B1 (da)	1983-12-16
EG15252A (en)	1986-09-30
DD144540A5 (de)	1980-10-22
ES480565A1 (es)	1980-08-16
PT69607A (en)	1979-06-01
IE790938L (en)	1979-11-15
NL7903769A (nl)	1979-11-19
HU180283B (en)	1983-02-28
SG65483G (en)	1984-07-27
DE2919514A1 (de)	1979-11-22
NL175524C (nl)	1984-11-16
US4173641A (en)	1979-11-06
AU4701679A (en)	1979-11-22
NO791604L (no)	1979-11-16
MY8500096A (en)	1985-12-31
IE48229B1 (en)	1984-11-14

Legal Events

Date	Code	Title	Description
1994-11-21	PBP	Patent lapsed

Publication	Publication Date	Title
DK46079A (da)	1979-08-07	Fremgangsmaade til fremstilling af alkylendiaminderivater
DK158225C (da)	1990-09-17	Analogifremgangsmaade til fremstilling af carbostyrilderivater
DK156779A (da)	1979-10-19	Fremgangsmaade til fremstilling af cycloalkyltriazoler
DK129879A (da)	1979-10-04	Fremgangsmaade til fremstilling af n-heterocyclyl-4-piperidinaminer
DK266479A (da)	1980-02-04	Fremgangsmaade til fremstilling af 3-aminopropoxyarylderivater
DK37879A (da)	1980-06-20	Fremgangsmaade til fremstilling af oligoimider
DK303079A (da)	1980-01-27	Fremgangsmaade til fremstilling af imidazolderivater
DK148879A (da)	1979-10-12	Fremgangsmaade til fremstilling af mercaptoimidazolderivater
DK186179A (da)	1979-12-10	Fremgangsmaade til fremstilling af carbapenemderivater
DK260579A (da)	1979-12-29	Fremgangsmaade til fremstilling af 14,15-methylenderivater af oestranraekken
DK117779A (da)	1979-09-24	Fremgangsmaade til fremstilling af 2,6-dialkoxybenzamider
DK382979A (da)	1980-03-15	Fremgangsmaade til fremstilling af 3" , 4"-diacyltylosinderivater
DK415379A (da)	1980-04-05	Fremgangsmaade til fremstilling af chromanolderivater
DK173379A (da)	1979-10-29	Fremgangsmaade til fremstilling af 6alfa-halogen-3-keto-delta 1,4-pregnadienderivater
HK13584A (en)	1984-02-24	1,2-and 1,3-(di-o-n-alkyl)glycerol derivatives
DK350079A (da)	1980-03-01	Fremgangsmaade til fremstilling af indolinderivater
DK150471C (da)	1987-11-30	Fremgangsmaade til fremstilling af trifluormethylphenoler
NO791458L (no)	1979-11-05	Fremgangsmaate til fremstilling av 1,2-dikloretan
DK160281C (da)	1991-07-29	Fremgangsmaade til fremstilling af steroid-s-thioesterderivater
DK282379A (da)	1980-01-06	Fremgangsmaade til fremstilling af phenylpiperidinderivater isaer substituerede eventuelt enkeltmaettede 1-benzylphenylpiperidiner
DK185179A (da)	1979-11-06	Fremgangsmaade til fremstilling af 3-halogen-2-hydroxyalkyltrialkylammoniumunchlorider
DK145179A (da)	1979-10-08	Fremgangsmaade til fremstilling af 4-methyl-5-hydroxymethyl-imidazol
DK348179A (da)	1980-02-22	Fremgangsmaade til fremstilling af carbazolyderivater
DK428079A (da)	1980-04-12	Fremgangsmaade til fremstilling af cyclohexadienderivater
DK157017C (da)	1990-03-26	Analogifremgangsmaade til fremstilling af carbostyrilderivater