DK1025237T3 - Human kontrolpunktskinase, hCDS1, præparater og fremgangsmåder - Google Patents

Human kontrolpunktskinase, hCDS1, præparater og fremgangsmåder

Info

Publication number
DK1025237T3
DK1025237T3 DK98966890T DK98966890T DK1025237T3 DK 1025237 T3 DK1025237 T3 DK 1025237T3 DK 98966890 T DK98966890 T DK 98966890T DK 98966890 T DK98966890 T DK 98966890T DK 1025237 T3 DK1025237 T3 DK 1025237T3
Authority
DK
Denmark
Prior art keywords
hcds1
protein
methods
preparations
checkpoint kinase
Prior art date
Application number
DK98966890T
Other languages
Danish (da)
English (en)
Inventor
Walter H M L Luyten
Andrew E Parker
Clare Mcgowan
Alessandra Blasina
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK1025237T3 publication Critical patent/DK1025237T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK98966890T 1997-10-22 1998-10-21 Human kontrolpunktskinase, hCDS1, præparater og fremgangsmåder DK1025237T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins

Publications (1)

Publication Number Publication Date
DK1025237T3 true DK1025237T3 (da) 2005-11-28

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
DK98966890T DK1025237T3 (da) 1997-10-22 1998-10-21 Human kontrolpunktskinase, hCDS1, præparater og fremgangsmåder
DK98955533T DK1025236T3 (da) 1997-10-22 1998-10-21 Human checkpoint kinase, HCDS1, præparater og fremgangsmåde

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK98955533T DK1025236T3 (da) 1997-10-22 1998-10-21 Human checkpoint kinase, HCDS1, præparater og fremgangsmåde

Country Status (13)

Country Link
US (4) US6413755B1 (fr)
EP (2) EP1025237B1 (fr)
JP (2) JP4261050B2 (fr)
AT (2) ATE304052T1 (fr)
AU (2) AU760544B2 (fr)
CA (2) CA2308013A1 (fr)
DE (2) DE69831500T2 (fr)
DK (2) DK1025237T3 (fr)
ES (2) ES2245050T3 (fr)
GB (1) GB9722320D0 (fr)
IL (2) IL135688A (fr)
NZ (2) NZ503983A (fr)
WO (2) WO1999025843A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
EP1090987A4 (fr) * 1998-06-23 2003-05-28 Chugai Pharmaceutical Co Ltd Facteur de regulation du cycle cellulaire
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
EP1257652A2 (fr) * 2000-02-18 2002-11-20 Lexicon Genetics Incorporated Nouvelles kinases humaines et nouveaux polynucleotides codant pour ces kinases
EP1265992A2 (fr) * 2000-03-08 2002-12-18 Zealand Pharma A/S SUBSTANCES ET PROCEDES LIES A LA DEGRADATION DE Cdc25A EN REPONSE A UN DOMMAGE DE L'ADN
WO2001081555A2 (fr) * 2000-04-20 2001-11-01 Incyte Genomics, Inc. Kinases humaines
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
CA2439800A1 (fr) * 2000-12-14 2002-06-20 Pe Corporation (Ny) Proteines kinases humaines isolees, molecules d'acide nucleique codant des proteines kinases humaines et utilisations associees
US6451538B1 (en) 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
WO2002051858A2 (fr) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Modulation antisens de l'expression de chk2
WO2002059325A2 (fr) * 2000-12-27 2002-08-01 Lexicon Genetics Incorporated Nouvelles kinases humaines et polynucleotides codant ces kinases
EP1224942A1 (fr) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Utilisation de JAQ1 (anticorps monoclonal anti-GPVI) en tant que médicament actif pour la protection contre les maladies thrombotiques
JP3990718B2 (ja) * 2003-01-09 2007-10-17 ファイザー・インク キナーゼ阻害剤としてのジアゼピノインドール誘導体
MXPA06002256A (es) * 2003-08-29 2006-05-17 Pfizer Naftaleno carboxamidas y sus derivados utiles como agentes anti-angiogenicos.
ES2314444T3 (es) * 2003-08-29 2009-03-16 Pfizer Inc. Tienopiridina-fenilacetaminasy sus derivados utiles como nuevos agentes antiangiogenicos.
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
CA2686848A1 (fr) 2007-05-08 2008-11-20 Schering Corporation Procedes de traitement par formulations intraveineuses comprenant du temozolomide
JP5576370B2 (ja) * 2008-08-06 2014-08-20 ファイザー・インク Ｃｈｋ−１阻害剤としての６置換２−ヘテロシクリルアミノピラジン化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
AU1461197A (en) * 1995-11-16 1997-06-05 Icos Corporation Cell cycle checkpoint pik-related kinase materials and methods
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
ES2245050T3 (es) 2005-12-16
DE69831500D1 (de) 2005-10-13
AU1232299A (en) 1999-05-10
US6943013B2 (en) 2005-09-13
WO1999020747A2 (fr) 1999-04-29
JP2001523461A (ja) 2001-11-27
AU752617B2 (en) 2002-09-26
IL135688A (en) 2010-04-29
US6531312B1 (en) 2003-03-11
US6413755B1 (en) 2002-07-02
IL135688A0 (en) 2001-05-20
DE69831007T2 (de) 2006-04-20
IL135687A (en) 2007-07-04
DK1025236T3 (da) 2005-10-24
EP1025237A2 (fr) 2000-08-09
JP2001520037A (ja) 2001-10-30
WO1999020747A3 (fr) 1999-07-01
WO1999025843A3 (fr) 1999-08-05
ATE300619T1 (de) 2005-08-15
ATE304052T1 (de) 2005-09-15
DE69831007D1 (de) 2005-09-01
JP4418103B2 (ja) 2010-02-17
EP1025237B1 (fr) 2005-09-07
NZ503965A (en) 2002-03-28
ES2245807T3 (es) 2006-01-16
CA2306492A1 (fr) 1999-05-27
AU760544B2 (en) 2003-05-15
JP4261050B2 (ja) 2009-04-30
AU2612699A (en) 1999-06-07
WO1999025843A2 (fr) 1999-05-27
EP1025236A2 (fr) 2000-08-09
GB9722320D0 (en) 1997-12-17
US20030017160A1 (en) 2003-01-23
NZ503983A (en) 2002-03-28
US20050180981A1 (en) 2005-08-18
EP1025236B1 (fr) 2005-07-27
IL135687A0 (en) 2001-05-20
DE69831500T2 (de) 2006-06-14
CA2308013A1 (fr) 1999-04-29
CA2306492C (fr) 2014-03-25
US7414020B2 (en) 2008-08-19

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