DK1026237T3 - Anvendelse af en inhibitor af Tau/neurofilament-proteinkinase PK40 - Google Patents
Anvendelse af en inhibitor af Tau/neurofilament-proteinkinase PK40Info
- Publication number
- DK1026237T3 DK1026237T3 DK00104460T DK00104460T DK1026237T3 DK 1026237 T3 DK1026237 T3 DK 1026237T3 DK 00104460 T DK00104460 T DK 00104460T DK 00104460 T DK00104460 T DK 00104460T DK 1026237 T3 DK1026237 T3 DK 1026237T3
- Authority
- DK
- Denmark
- Prior art keywords
- kinases
- tau
- inhibitor
- protein kinase
- neurofilament protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74288091A | 1991-08-09 | 1991-08-09 | |
| EP92915162A EP0667898B1 (en) | 1991-08-09 | 1992-07-10 | Uses of the tau/neurofilament protein kinase pk40 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1026237T3 true DK1026237T3 (da) | 2004-07-19 |
Family
ID=24986618
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92915162T DK0667898T3 (da) | 1991-08-09 | 1992-07-10 | Anvendelser af TAU/neurofilamentproteinkinasen PK40 |
| DK00104460T DK1026237T3 (da) | 1991-08-09 | 1992-07-10 | Anvendelse af en inhibitor af Tau/neurofilament-proteinkinase PK40 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92915162T DK0667898T3 (da) | 1991-08-09 | 1992-07-10 | Anvendelser af TAU/neurofilamentproteinkinasen PK40 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP0667898B1 (da) |
| JP (1) | JPH06510427A (da) |
| AT (2) | ATE262584T1 (da) |
| AU (1) | AU675410B2 (da) |
| CA (1) | CA2115151C (da) |
| DE (2) | DE69232121T2 (da) |
| DK (2) | DK0667898T3 (da) |
| ES (2) | ES2165358T3 (da) |
| WO (1) | WO1993003148A2 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993011231A1 (en) | 1991-12-06 | 1993-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Tools for the diagnosis and treatment of alzheimer's disease |
| US7408027B1 (en) | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
| EP0646129A4 (en) * | 1992-05-11 | 1995-07-19 | Ludwig Inst Cancer Res | MOLECULES, WHICH ARE SIMILAR TO THE TYROSIN KINASE OF THE RECEPTOR TYPE (01/13/94). |
| US6013646A (en) | 1998-07-02 | 2000-01-11 | Bayer Corporation | Indolocarbazole derivatives useful for the treatment of neurodegenerative diseases and cancer |
| BR0112259A (pt) * | 2000-07-07 | 2004-03-30 | Milliken & Co | Substratos têxteis com melhor repelência à água e liberação de sujeira duráveis e método para produzir os mesmos |
| JP5186212B2 (ja) | 2004-09-23 | 2013-04-17 | ウィスタ ラボラトリーズ リミテッド | メチルチオニニウム塩化物(mtc)などのジアミノフェノチアジニウム化合物を化学合成および精製する方法 |
| ES2600915T3 (es) * | 2011-10-07 | 2017-02-13 | Ac Immune S.A. | Anticuerpos fosfoespecíficos que reconocen Tau |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU643235B2 (en) * | 1989-09-15 | 1993-11-11 | Gensia Pharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
| HUT61567A (en) * | 1990-12-07 | 1993-01-28 | Sandoz Ag | Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate |
| WO1993003177A1 (en) * | 1991-08-09 | 1993-02-18 | Massachusetts Institute Of Technology | Novel tau/neurofilament protein kinases |
| EP0544942A1 (en) * | 1991-12-06 | 1993-06-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel tools for the diagnosis and treatment of Alzheimer disease |
-
1992
- 1992-07-10 DE DE69232121T patent/DE69232121T2/de not_active Expired - Fee Related
- 1992-07-10 JP JP5503575A patent/JPH06510427A/ja active Pending
- 1992-07-10 AT AT00104460T patent/ATE262584T1/de not_active IP Right Cessation
- 1992-07-10 AU AU23240/92A patent/AU675410B2/en not_active Ceased
- 1992-07-10 ES ES92915162T patent/ES2165358T3/es not_active Expired - Lifetime
- 1992-07-10 EP EP92915162A patent/EP0667898B1/en not_active Expired - Lifetime
- 1992-07-10 DK DK92915162T patent/DK0667898T3/da active
- 1992-07-10 CA CA002115151A patent/CA2115151C/en not_active Expired - Fee Related
- 1992-07-10 WO PCT/US1992/005825 patent/WO1993003148A2/en not_active Ceased
- 1992-07-10 AT AT92915162T patent/ATE206755T1/de not_active IP Right Cessation
- 1992-07-10 DK DK00104460T patent/DK1026237T3/da active
- 1992-07-10 EP EP00104460A patent/EP1026237B1/en not_active Expired - Lifetime
- 1992-07-10 ES ES00104460T patent/ES2216745T3/es not_active Expired - Lifetime
- 1992-07-10 DE DE69233330T patent/DE69233330T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69232121D1 (de) | 2001-11-15 |
| DK0667898T3 (da) | 2002-02-04 |
| ES2216745T3 (es) | 2004-11-01 |
| ATE206755T1 (de) | 2001-10-15 |
| AU675410B2 (en) | 1997-02-06 |
| CA2115151A1 (en) | 1993-02-18 |
| EP1026237A2 (en) | 2000-08-09 |
| DE69233330D1 (de) | 2004-04-29 |
| EP0667898A1 (en) | 1995-08-23 |
| ES2165358T3 (es) | 2002-03-16 |
| WO1993003148A3 (en) | 1993-04-01 |
| EP0667898B1 (en) | 2001-10-10 |
| DE69232121T2 (de) | 2002-06-20 |
| AU2324092A (en) | 1993-03-02 |
| ATE262584T1 (de) | 2004-04-15 |
| EP1026237A3 (en) | 2001-03-28 |
| JPH06510427A (ja) | 1994-11-24 |
| EP1026237B1 (en) | 2004-03-24 |
| DE69233330T2 (de) | 2005-03-10 |
| CA2115151C (en) | 2005-05-17 |
| WO1993003148A2 (en) | 1993-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69534300D1 (de) | Neues multimerisierendes reagenz | |
| EA199700061A1 (ru) | Способ получения силденафила | |
| DE68929387D1 (de) | Interleukin-1-Inhibitoren | |
| NO944643D0 (no) | Protein-kinase-C-hemmere | |
| IE892272L (en) | Novel fused heterocyclic compounds | |
| TR199800759T2 (xx) | Protein Kinaz C �nhibit�r�. | |
| DE69412828D1 (de) | Zusammensetzung zur benetzung von kontaktlinsen | |
| ATE236886T1 (de) | 2,4-dioxo-imidazolidin-derivate | |
| DK0788356T3 (da) | Fremgangsmåde og præparater til hæmning af proteinkinaser | |
| AU2178895A (en) | Heterocyclic-cyclic amine derivatives | |
| DK0619806T3 (da) | Fremstilling af substituerede piperidiner | |
| DE59507591D1 (de) | Stabile kristalline (6S)- und (6R)-Tetrahydrofolsäure | |
| PT83535B (pt) | Processo para a preparacao de composicoes farmaceuticas contendo derivados de aminoacidos | |
| DE68917556D1 (de) | Quinolyloxazol-2-one, nützlich als Proteinkinase-C-Inhibitoren. | |
| DK0638068T3 (da) | Fremgangsmåde til fremstilling af (S)-3-amino-1-substitueret-pyrrolidiner | |
| DK0667898T3 (da) | Anvendelser af TAU/neurofilamentproteinkinasen PK40 | |
| DK0589949T3 (da) | Hidtil ukendte peptider, fremgangsmåder til fremstilling heraf og anvendelse af disse | |
| DE59900730D1 (de) | Korrosionsinhibitoren enthaltender Injektionszement | |
| DK0640608T3 (da) | Mellemprodukter til syntese af cephalosporiner | |
| AR022150A1 (es) | Acidos nucleicos derivados de monocitos y composiciones y metodos relacionados | |
| DK192890A (da) | 24r-scumnol, fremgangsmaade til fremstilling heraf samt anvendelse af samme | |
| DK0689440T3 (da) | Anvendelse af triazinforbindelser som anxiolytikum | |
| TR199701011A2 (xx) | 1-karba-(detia)-sefalosforin t�revleri. | |
| DK509085D0 (da) | Fremgangsmaade til stabilisering af bacampicillinhydroklorid | |
| FI920926A7 (fi) | Menetelmä korkea-alkalisten proteaasien stabiilisuuden parantamiseksi |