DK1027055T3 - 3-Carboalkoxy-2,3-dihydro-1H-phenothiazin-4(10H)-on-derivater - Google Patents

3-Carboalkoxy-2,3-dihydro-1H-phenothiazin-4(10H)-on-derivater

Info

Publication number
DK1027055T3
DK1027055T3 DK98955131T DK98955131T DK1027055T3 DK 1027055 T3 DK1027055 T3 DK 1027055T3 DK 98955131 T DK98955131 T DK 98955131T DK 98955131 T DK98955131 T DK 98955131T DK 1027055 T3 DK1027055 T3 DK 1027055T3
Authority
DK
Denmark
Prior art keywords
phenothiazin
carboalkoxy
dihydro
derivatives
coor
Prior art date
Application number
DK98955131T
Other languages
English (en)
Inventor
Ralph R Roberts
Kenneth R Scott
Mia L Laws
Jesse M Nicholson
Original Assignee
Univ Howard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Howard filed Critical Univ Howard
Application granted granted Critical
Publication of DK1027055T3 publication Critical patent/DK1027055T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98955131T 1997-10-27 1998-10-27 3-Carboalkoxy-2,3-dihydro-1H-phenothiazin-4(10H)-on-derivater DK1027055T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/958,320 US5994349A (en) 1997-10-27 1997-10-27 3-carboalkoxy-2, 3-dihydro-1H-phenothiazin-4[10H]-one derivatives
PCT/US1998/022693 WO1999021560A1 (en) 1997-10-27 1998-10-27 3-carboalkoxy-2,3-dihydro-1h-phenothiazin-4[10h]-one derivatives

Publications (1)

Publication Number Publication Date
DK1027055T3 true DK1027055T3 (da) 2004-04-26

Family

ID=25500854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98955131T DK1027055T3 (da) 1997-10-27 1998-10-27 3-Carboalkoxy-2,3-dihydro-1H-phenothiazin-4(10H)-on-derivater

Country Status (11)

Country Link
US (1) US5994349A (da)
EP (1) EP1027055B1 (da)
AT (1) ATE257382T1 (da)
AU (1) AU748596B2 (da)
CA (1) CA2308281C (da)
DE (1) DE69821019T2 (da)
DK (1) DK1027055T3 (da)
ES (1) ES2212370T3 (da)
IL (1) IL135842A (da)
PT (1) PT1027055E (da)
WO (1) WO1999021560A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201536795A (zh) 2013-05-31 2015-10-01 Medeia Therapeutics Ltd 作為細胞保護劑用之芳基噻嗪化合物
CN106117247B (zh) * 2016-06-29 2018-02-16 东华大学 一种2‑甲基‑1,2,3,9‑四氢苯并[b]吡咯[1,4]‑噻嗪‑1,3‑二酮类化合物的制备方法
US12084461B2 (en) 2018-09-03 2024-09-10 Hoffmann-La Roche Inc. Bicyclic heteroaryl derivatives
BR112021009443A2 (pt) 2018-12-13 2021-08-17 F. Hoffmann-La Roche Ag derivados de 7-fenóxi-n-(3-azabiciclo[3.2.1]octan-8-il)-6,7-di-hidro-5h-pirrolo[1,2-b][1,2,4]triazol-2-amina e compostos relacionados como moduladores de gama-secretase para o tratamento da doença de alzheimer.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3229122A1 (de) * 1982-08-04 1984-02-09 Bayer Ag, 5090 Leverkusen Anellierte 4h-1,4-benzothiazine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3426564A1 (de) * 1984-07-19 1986-01-30 Bayer Ag, 5090 Leverkusen Verwendung von 4h-1,4-benzothiazinen bei der prophylaxe und therapie von erkrankungen der atemwege, entzuendungen/rheuma, thromboembolischen erkrankungen, ischaemien und infarkten, herzrhythmusstoerungen, arteriosklerose und dermatosen, arzneimittel zu diesem zweck sowie wirkstoffe, die in diesen arzneimitteln enthalten sind
US5580894A (en) * 1996-01-11 1996-12-03 Howard University Isoxazolyl enaminones

Also Published As

Publication number Publication date
US5994349A (en) 1999-11-30
PT1027055E (pt) 2004-05-31
IL135842A (en) 2004-06-01
AU748596B2 (en) 2002-06-06
DE69821019D1 (en) 2004-02-12
ATE257382T1 (de) 2004-01-15
ES2212370T3 (es) 2004-07-16
IL135842A0 (en) 2001-05-20
DE69821019T2 (de) 2004-10-28
EP1027055A1 (en) 2000-08-16
AU1201399A (en) 1999-05-17
CA2308281A1 (en) 1999-05-06
WO1999021560A1 (en) 1999-05-06
EP1027055B1 (en) 2004-01-07
EP1027055A4 (en) 2001-12-05
CA2308281C (en) 2004-08-24

Similar Documents

Publication Publication Date Title
HUP9700777A2 (hu) Ösztrogén hatású 2-fenil-1[4-(2-amino-etoxi)-benzil]-indol-származékok, előállításuk és alkalmazásuk, valamint ezeket a vegyületeket tartalmazó gyógyszerkészítmények
PT870768E (pt) Derivados azaindole-etilamina como agentes de ligacao nicotinicos aos receptores de acetilcolina
TR199902897T2 (xx) S�v� benz-izo-kuinolin t�revleri.
IE811085L (en) Pyridoxine derivatives
MY123083A (en) Acyclic nucleoside derivatives
NO306510B1 (no) Androsteroner, anvendelse derav og farmasöytisk formulering
DE3376421D1 (en) Analgesia-effecting 5-hydroxytryptophan derivatives
AU526764B2 (en) Ergoline derivatives
AU601687B2 (en) New derivatives of carboxamide indole, their salts, process and intermediates for preparation, use as medicaments and compositions containing them
DK1027055T3 (da) 3-Carboalkoxy-2,3-dihydro-1H-phenothiazin-4(10H)-on-derivater
NO995935D0 (no) 17<beta>-allyloksy(tio)alkyl-androstan-derivater for modulering av meiose
MY104955A (en) Pyrroloquinoline and pyrrolophemothiazine carboxamides and related compounds.
IE812498L (en) Pyrimidine derivatives.
DE3668456D1 (de) 8-thiotetrahydrochinoleinderivate und deren salze.
YU200791A (sh) Trifluorometil 1-karba (1-detia) cefemi
CO5140085A1 (es) Derivados terapeuticos de benzamida
AU551901B2 (en) Substituted thienobenzodiazepinones
AU535927B2 (en) 2-phenylamino-imidazolines
JPS56154431A (en) Substituted 3-aryl-2-cycloalkene-1-one and its manufacture
IE801888L (en) Trans-fused decahydroquinolinol derivatives
CO4920233A1 (es) Acidos aminobutiricos gamma substituidos como agentes farmaceuticos
AU561149B2 (en) Cardiotonic 4-semicarbazide quindyolines