DK1027343T3 - Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner - Google Patents

Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner

Info

Publication number
DK1027343T3
DK1027343T3 DK98948584T DK98948584T DK1027343T3 DK 1027343 T3 DK1027343 T3 DK 1027343T3 DK 98948584 T DK98948584 T DK 98948584T DK 98948584 T DK98948584 T DK 98948584T DK 1027343 T3 DK1027343 T3 DK 1027343T3
Authority
DK
Denmark
Prior art keywords
preparation
butyrolactones
hydroxy
substituted gamma
methyl ester
Prior art date
Application number
DK98948584T
Other languages
Danish (da)
English (en)
Inventor
Rawle I Hollingsworth
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25505755&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1027343(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Michigan State filed Critical Univ Michigan State
Application granted granted Critical
Publication of DK1027343T3 publication Critical patent/DK1027343T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D315/00Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)
DK98948584T 1997-10-31 1998-09-29 Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner DK1027343T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/962,365 US5808107A (en) 1997-10-31 1997-10-31 Process for the preparation of hydroxy substituted gamma butyrolactones
PCT/US1998/020448 WO1999023086A1 (fr) 1997-10-31 1998-09-29 Procede de preparation de gamma butyrolactones a substitution hydroxy

Publications (1)

Publication Number Publication Date
DK1027343T3 true DK1027343T3 (da) 2003-03-31

Family

ID=25505755

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98948584T DK1027343T3 (da) 1997-10-31 1998-09-29 Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner

Country Status (11)

Country Link
US (2) US5808107A (fr)
EP (1) EP1027343B2 (fr)
JP (1) JP3527706B2 (fr)
KR (1) KR100369857B1 (fr)
AT (1) ATE229013T1 (fr)
CA (1) CA2304809C (fr)
DE (1) DE69809962T3 (fr)
DK (1) DK1027343T3 (fr)
ES (1) ES2188017T5 (fr)
PT (1) PT1027343E (fr)
WO (1) WO1999023086A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618099D0 (en) 1996-08-30 1996-10-09 Zeneca Ltd Process
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
US6949684B2 (en) 1998-03-03 2005-09-27 Daiso Co., Ltd. Process for preparing 1,2,4-butanetriol
KR100622963B1 (ko) * 1998-03-03 2006-09-12 다이소 가부시키가이샤 1,2,4-부탄트리올의 제조 방법
US6040464A (en) * 1998-06-01 2000-03-21 Board Of Trustees Operating Michigan State University Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof
US6084131A (en) * 1998-06-01 2000-07-04 Board Of Trustees Operating Michigan State University Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof
US6713290B2 (en) * 1998-07-24 2004-03-30 Samsung Fine Chemicals Co., Ltd. Process for preparing optically pure (S)-3-hydroxy-γ-butyrolactone
JP2002521031A (ja) * 1998-07-24 2002-07-16 サムスン ファイン ケミカルズ カンパニー リミテッド α−(1,4)結合したオリゴサッカリドの製造方法
US6423850B1 (en) * 1999-06-18 2002-07-23 E.I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
KR100645665B1 (ko) * 2000-07-27 2006-11-13 에스케이 주식회사 (s)-베타-하이드록시-감마-부티로락톤의 연속 제조방법
US6288239B1 (en) 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
US6288238B1 (en) 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University Process for the preparation of 5-hydroxymethyl 2-oxazolidinone and novel intermediate
JP4824874B2 (ja) 2001-07-19 2011-11-30 高砂香料工業株式会社 光学活性γ−ブチロラクトンの製造方法
EP1398312A1 (fr) * 2002-09-13 2004-03-17 Hong-Sun Uh Gamma-butyrolactones substituées en position béta et procédé pour leur préparation
ATE394384T1 (de) * 2002-09-18 2008-05-15 Sk Holdings Co Ltd Kontinuierliches verfahren zur herstellung von optisch reinem (s)-beta hydroxy- gamma- butyrolacton
WO2005068642A2 (fr) 2003-10-01 2005-07-28 Board Of Trustees Operating Michigan State University Synthese d'enantiomeres 1,2,4-butanetriol issue de glucides
CN100335457C (zh) * 2005-09-08 2007-09-05 上海交通大学 3-位手性羟基被保护的3,4-二羟基丁酸酯及其制备方法
WO2007100227A1 (fr) * 2006-03-02 2007-09-07 Lg Chem, Ltd. Procédé de préparation de (s)-3-hydroxy-gamma-butyrolactone utilisant une hydrolase
US20110165641A1 (en) * 2006-03-31 2011-07-07 The Board Of Trustees Of Michigan State University Synthesis of 1,2,4-Butanetriol Enantiomers from Carbohydrates
CN101512004A (zh) * 2006-07-19 2009-08-19 密歇根州州立大学托管委员会 D-1,2,4-丁三醇的微生物合成
CN100441573C (zh) * 2006-07-20 2008-12-10 厦门大学 一种合成s-(3)-羟基四氢呋喃的方法
WO2010101651A1 (fr) * 2009-03-06 2010-09-10 Massachusetts Institute Of Technology Production microbienne de 3-hydroxyacides à partir du glucose et du glycolate
WO2012116307A1 (fr) 2011-02-25 2012-08-30 Massachusetts Institute Of Technology Production microbienne de 3,4-dihydroxybutyrate (3,4-dhba), de 2,3-dihydroxybutyrate (2,3-dhba) et de 3-hydroxybutyrolactone (3-hbl)
EP3835285A1 (fr) * 2016-03-15 2021-06-16 Shionogi & Co., Ltd Procédé de production d'un dérivé de phénoxyéthanol
WO2019126216A1 (fr) 2017-12-18 2019-06-27 Tris Phama, Inc. Compositions pharmaceutiques comprenant un système formant un réseau polymère d'interpénétration flottant
WO2019126214A1 (fr) 2017-12-18 2019-06-27 Tris Pharma, Inc. Composition pharmaceutique comprenant des systèmes formant un radeau de rétention gastrique de ghb à libération de médicament par impulsions de déclenchement
JP2021506984A (ja) 2017-12-18 2021-02-22 トリス・フアルマ・インコーポレーテツド トリガーパルス薬物放出を有する胃内滞留型raft形成システムを含む放出調節薬物粉末組成物
EP3737353A1 (fr) 2017-12-18 2020-11-18 Tris Pharma, Inc. Compositions pharmaceutiques de ghb comprenant un système de formation de réseau polymère interpénétrant flottant
FR3088324B1 (fr) * 2018-11-08 2020-10-09 Inst Des Sciences Et Industries Du Vivant Et De Lenvironnement Agroparistech Procede biocatalytique de production de 2h-hbo a partir de lgo utilisant une cyclohexanone monooxygenase
CN112939901B (zh) * 2021-02-09 2023-05-09 中国科学院福建物质结构研究所 一种α-羟基-γ-丁内酯的制备方法
EP4658242A1 (fr) 2023-02-03 2025-12-10 Tris Pharma, Inc. Composition d'oxybate faible en sodium à dose unique pour la nuit

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3024250A (en) * 1962-03-06 Certificate of correction
US2683721A (en) * 1952-01-17 1954-07-13 Hermann I Schlesinger Method of reducing and hydrogenating chemical compounds by reacting with alkali metal borohydrides
US3997569A (en) * 1972-11-08 1976-12-14 Texaco Inc. Method for preparing a lactone reaction product
US3868370A (en) * 1973-02-09 1975-02-25 Gen Electric Process for making 4-butyrolactone
US4083809A (en) * 1976-08-20 1978-04-11 Gaf Corporation Hydrogenation catalyst and method of producing same
GB1587198A (en) * 1976-11-23 1981-04-01 Ucb Sa Process for the production of butane-1,4 diol and tetrahydrofuran
US4772729A (en) * 1987-01-23 1988-09-20 E. I. Du Pont De Nemours And Company Hydrogenation of citric acid and substituted citric acids to 3-substituted tetrahydrofuran, 3- and 4-substituted butyrolactones and mixtures thereof
EP0304696B1 (fr) * 1987-08-08 1992-04-29 BASF Aktiengesellschaft Procédé pour la préparation de 1,4-butanediol et/ou tétrahydrofuranne
US5087751A (en) * 1988-04-27 1992-02-11 Kanegafuchi Kagaku Kogyo K.K. Method of preparing optically active 3,4-dihydroxy butyric acid derivatives
CA1307796C (fr) * 1988-04-27 1992-09-22 Kenji Inoue Methode pour la preparation de derives optiquement actifs de l'acide 3,4-dihydroxybutyrique
CA2049536C (fr) * 1991-05-13 1999-07-06 Rawle I. Hollingsworth Procede d'obtention d'acide 3,4-dihydroxybutanoique et de ses sels
EP0543340B1 (fr) * 1991-11-18 1998-05-20 Tosoh Corporation Procédé pour la préparation des lactones
GB9618099D0 (en) 1996-08-30 1996-10-09 Zeneca Ltd Process

Also Published As

Publication number Publication date
US5808107A (en) 1998-09-15
ES2188017T5 (es) 2006-07-16
USRE38324E1 (en) 2003-11-18
CA2304809A1 (fr) 1999-05-14
DE69809962D1 (de) 2003-01-16
DE69809962T2 (de) 2003-04-24
PT1027343E (pt) 2003-04-30
EP1027343A1 (fr) 2000-08-16
JP3527706B2 (ja) 2004-05-17
KR20010031475A (ko) 2001-04-16
WO1999023086A1 (fr) 1999-05-14
ATE229013T1 (de) 2002-12-15
EP1027343A4 (fr) 2001-08-22
KR100369857B1 (ko) 2003-02-05
EP1027343B1 (fr) 2002-12-04
ES2188017T3 (es) 2003-06-16
JP2001521931A (ja) 2001-11-13
DE69809962T3 (de) 2006-12-14
EP1027343B2 (fr) 2006-01-11
CA2304809C (fr) 2006-08-01

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