DK1027891T3 - Neuropeptid-Y-antagonister - Google Patents

Neuropeptid-Y-antagonister

Info

Publication number: DK1027891T3
Authority: DK; Denmark
Prior art keywords: neuropeptide; antagonists; disorders; antagonist; chem
Prior art date: 1999-01-27

Application number

DK99310483T

Other languages

English (en)

Inventor

Marlys Hammond

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-27

Filing date

1999-12-23

Publication date

2005-05-09

1999-12-23 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2005-05-09 Application granted granted Critical

2005-05-09 Publication of DK1027891T3 publication Critical patent/DK1027891T3/da

Links

101710151321 Melanostatin Proteins 0.000 title 1
102100028427 Pro-neuropeptide Y Human genes 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 title 1
208000024172 Cardiovascular disease Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000002660 neuropeptide Y receptor antagonist Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Neurology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Gynecology & Obstetrics (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Reproductive Health (AREA)
Addiction (AREA)
Rheumatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

DK99310483T 1999-01-27 1999-12-23 Neuropeptid-Y-antagonister DK1027891T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11739599P	1999-01-27	1999-01-27
EP99310483A EP1027891B1 (en)	1999-01-27	1999-12-23	Neuropeptide y antagonists

Publications (1)

Publication Number	Publication Date
DK1027891T3 true DK1027891T3 (da)	2005-05-09

Family

ID=22372692

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99310483T DK1027891T3 (da)	1999-01-27	1999-12-23	Neuropeptid-Y-antagonister

Country Status (17)

Country	Link
US (1)	US6197822B1 (da)
EP (1)	EP1027891B1 (da)
JP (1)	JP3502586B2 (da)
KR (1)	KR100372989B1 (da)
AT (1)	ATE285759T1 (da)
AU (1)	AU1352000A (da)
CA (1)	CA2296970C (da)
CO (1)	CO5170482A1 (da)
DE (1)	DE69922918T2 (da)
DK (1)	DK1027891T3 (da)
ES (1)	ES2234218T3 (da)
HU (1)	HUP0000307A2 (da)
IL (1)	IL134157A0 (da)
NZ (1)	NZ502518A (da)
PE (1)	PE20001416A1 (da)
PT (1)	PT1027891E (da)
ZA (1)	ZA200000313B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6407120B1 (en) *	1999-02-18	2002-06-18	Pfizer Inc.	Neuropeptide Y antagonists
US8377906B2 (en)	2004-06-04	2013-02-19	Ethicon, Inc.	Compositions and methods for preventing or reducing postoperative ileus and gastric stasis
US20070141156A1 (en) *	2005-12-21	2007-06-21	Uri Herzberg	Compositions and methods for preventing or reducing postoperative ileus and gastric stasis
US8129359B2 (en)	2004-06-04	2012-03-06	Ethicon, Inc.	Composition and method for treating post-surgical pain
US8883960B2 (en)	2007-01-04	2014-11-11	Sk Chemicals Co., Ltd.	Polyarylene sulfide resin with excellent luminosity and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6562862B1 (en) *	1994-10-20	2003-05-13	Eli Lilly And Company	Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
CZ137297A3 (cs) *	1994-11-07	1998-04-15	Pfizer Inc.	Substituované benzylaminové deriváty
EP0759441A3 (en) *	1995-06-30	1999-06-30	Eli Lilly And Company	Methods of treating neuropeptide Y-associated conditions
US6048900A (en) *	1998-02-13	2000-04-11	Bayer Corporation	Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
EP1033366A3 (en) *	1999-02-18	2000-12-27	Pfizer Products Inc.	Amide derivatives useful as Neuropeptide Y (NPY) antagonists

1999
- 1999-12-23 DE DE69922918T patent/DE69922918T2/de not_active Expired - Fee Related
- 1999-12-23 AT AT99310483T patent/ATE285759T1/de not_active IP Right Cessation
- 1999-12-23 ES ES99310483T patent/ES2234218T3/es not_active Expired - Lifetime
- 1999-12-23 PT PT99310483T patent/PT1027891E/pt unknown
- 1999-12-23 EP EP99310483A patent/EP1027891B1/en not_active Expired - Lifetime
- 1999-12-23 DK DK99310483T patent/DK1027891T3/da active
- 1999-12-29 CO CO99081405A patent/CO5170482A1/es not_active Application Discontinuation
2000
- 2000-01-20 IL IL13415700A patent/IL134157A0/xx unknown
- 2000-01-24 AU AU13520/00A patent/AU1352000A/en not_active Abandoned
- 2000-01-25 US US09/491,293 patent/US6197822B1/en not_active Expired - Fee Related
- 2000-01-25 ZA ZA200000313A patent/ZA200000313B/xx unknown
- 2000-01-25 CA CA002296970A patent/CA2296970C/en not_active Expired - Fee Related
- 2000-01-26 NZ NZ502518A patent/NZ502518A/en unknown
- 2000-01-26 PE PE2000000055A patent/PE20001416A1/es not_active Application Discontinuation
- 2000-01-26 HU HU0000307A patent/HUP0000307A2/hu unknown
- 2000-01-26 KR KR10-2000-0003550A patent/KR100372989B1/ko not_active Expired - Fee Related
- 2000-01-27 JP JP2000018938A patent/JP3502586B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69922918T2 (de)	2006-03-30
CA2296970A1 (en)	2000-07-27
HUP0000307A2 (hu)	2000-12-28
CO5170482A1 (es)	2002-06-27
HU0000307D0 (en)	2000-03-28
ES2234218T3 (es)	2005-06-16
JP2000212077A (ja)	2000-08-02
KR100372989B1 (ko)	2003-02-25
AU1352000A (en)	2000-08-03
PT1027891E (pt)	2005-04-29
US6197822B1 (en)	2001-03-06
EP1027891A3 (en)	2002-07-17
IL134157A0 (en)	2001-04-30
PE20001416A1 (es)	2000-12-18
ATE285759T1 (de)	2005-01-15
DE69922918D1 (de)	2005-02-03
KR20000053607A (ko)	2000-08-25
EP1027891B1 (en)	2004-12-29
NZ502518A (en)	2001-06-29
JP3502586B2 (ja)	2004-03-02
CA2296970C (en)	2004-11-02
ZA200000313B (en)	2001-07-25
EP1027891A2 (en)	2000-08-16

Publication	Publication Date	Title
EA200300717A1 (ru)	2003-12-25	Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов
FR2829362B1 (fr)	2003-11-07	Composition fongicide a base de derives d'arylamidine et de composes fongicides connus
ATE302770T1 (de)	2005-09-15	Benzimidazolverbindungen die nociceptinrezeptoraffinität haben
PL372965A1 (en)	2005-08-08	2-(2,6-dichlorophenyl)-diarylimidazoles
IS2839B (is)	2013-06-15	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl)pyrazolo-(1,5-A-)-1,3,5 triazine, handhverfur þess og lyfjafræðilega ásættanleg sölt sem tenglar við viðtaka fyrir "corticotropin releasing factor"
IL145684A0 (en)	2002-06-30	Treatment of pulmonary hypertension
TR200102178T2 (tr)	2002-01-21	CRF reseptör antagonistleri ve bunlarla ilgili yöntemler.
NO20020793D0 (no)	2002-02-18	Virkestoffkombinasjon med clonidin
EA200200742A1 (ru)	2002-12-26	1,2-диарилбензимидазолы для лечения заболеваний, связанных с активацией микроглии
ITMI20021729A1 (it)	2004-02-02	Apparecchio emanatore per l'emanazione di soluzioni.
NO20014486D0 (no)	2001-09-14	Nye LHRH antagonister med forbedrede opplöselighetsegenskaper
DK1027891T3 (da)	2005-05-09	Neuropeptid-Y-antagonister
BR0000486A (pt)	2001-08-21	Antagonistas do neuropeptìdeo y
PT896822E (pt)	2003-07-31	4-aminopirrolo (3,2-d)pirimidinas como antagonistas do receptor de neuropeptideo y
ATE321497T1 (de)	2006-04-15	Tibiamarknagel
NZ516209A (en)	2004-01-30	Indoloazepines as vasopressin receptor antagonists
LU90560B1 (fr)	2001-11-23	B-timent d'-levage d'animaux - ventelles
DE69925008D1 (de)	2005-06-02	Protein, welches die aktivität von d1-ähnlichen dopamin rezeptoren modifiziert
ITAT990002U1 (it)	1999-04-29	Progetto "millenium due"
ES1042371Y (es)	2000-01-16	"elevador perfeccionado".
ITMI20022199A1 (it)	2003-04-26	Dispositivo per l'alimentazione del pollame
ITMI20000005A0 (it)	2000-01-05	Benzilisotiourre ad attivita' fungicida
ES1042496Y (es)	2000-02-01	"pilona sumible".
ES1042364Y (es)	2000-01-16	"pañal perfeccionado".
ITVE20010020U1 (it)	2003-05-30	"macchina profilatrice".-