DK1030697T3 - Bionedbrydeligt polymerskelet - Google Patents
Bionedbrydeligt polymerskeletInfo
- Publication number
- DK1030697T3 DK1030697T3 DK98954085T DK98954085T DK1030697T3 DK 1030697 T3 DK1030697 T3 DK 1030697T3 DK 98954085 T DK98954085 T DK 98954085T DK 98954085 T DK98954085 T DK 98954085T DK 1030697 T3 DK1030697 T3 DK 1030697T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymer
- scaffold
- polymer scaffold
- particles
- solvent
- Prior art date
Links
- 229920002988 biodegradable polymer Polymers 0.000 title abstract 2
- 239000004621 biodegradable polymer Substances 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 9
- 239000007788 liquid Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 1
- 229920000954 Polyglycolide Polymers 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229920000747 poly(lactic acid) Polymers 0.000 abstract 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3847—Bones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Botany (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Biological Depolymerization Polymers (AREA)
- Polyesters Or Polycarbonates (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Polyurethanes Or Polyureas (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002221195A CA2221195A1 (en) | 1997-11-14 | 1997-11-14 | Biodegradable polymer matrix |
| PCT/CA1998/001052 WO1999025391A2 (en) | 1997-11-14 | 1998-11-13 | Biodegradable polymer scaffold |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1030697T3 true DK1030697T3 (da) | 2003-12-29 |
Family
ID=4161772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98954085T DK1030697T3 (da) | 1997-11-14 | 1998-11-13 | Bionedbrydeligt polymerskelet |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6379962B1 (da) |
| EP (1) | EP1030697B1 (da) |
| JP (1) | JP4636684B2 (da) |
| KR (1) | KR100664772B1 (da) |
| CN (1) | CN1212866C (da) |
| AT (1) | ATE247994T1 (da) |
| AU (2) | AU749041B2 (da) |
| BR (1) | BR9814036B1 (da) |
| CA (2) | CA2221195A1 (da) |
| DE (1) | DE69817600T2 (da) |
| DK (1) | DK1030697T3 (da) |
| ES (1) | ES2207861T3 (da) |
| IL (1) | IL136093A0 (da) |
| NZ (1) | NZ504973A (da) |
| WO (1) | WO1999025391A2 (da) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR876M (da) | 1960-10-12 | 1961-10-16 | ||
| US7022522B2 (en) * | 1998-11-13 | 2006-04-04 | Limin Guan | Macroporous polymer scaffold containing calcium phosphate particles |
| AU3844599A (en) * | 1999-05-07 | 2000-11-21 | Salviac Limited | Biostable polyether polyurethane product |
| EP1176995A1 (en) * | 1999-05-07 | 2002-02-06 | Salviac Limited | A tissue engineering scaffold |
| JP3421741B2 (ja) * | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
| US6835390B1 (en) * | 2000-11-17 | 2004-12-28 | Jon Vein | Method for producing tissue engineered meat for consumption |
| DE10126137C1 (de) * | 2001-05-29 | 2002-11-07 | Andreas Haisch | Verfahren zur Herstellung von Zellen, Geweben und Organen |
| WO2003004254A1 (en) * | 2001-07-03 | 2003-01-16 | The Regents Of The University Of California | Microfabricated biopolymer scaffolds and method of making same |
| DE60215895T2 (de) * | 2001-09-13 | 2007-05-31 | Akira Myoi, Toyonaka | Poröse Calciumphosphat-Keramik für in vivo-Anwendungen |
| US9969980B2 (en) | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| NL1019888C2 (nl) * | 2002-02-01 | 2003-08-25 | Univ Twente | Werkwijze voor het vervaardigen van een poreuze polymeerstructuur. |
| EP1490520A4 (en) * | 2002-03-12 | 2006-06-07 | Surface Logix Inc | TEST APPARATUS ANALYZING THE ABSORPTION, METABOLISM, PERMEABILITY AND / OR TOXICITY OF A CANDIDATE COMPOUND |
| US20030181978A1 (en) | 2002-03-25 | 2003-09-25 | Brown Kelly R. | Channeled biomedical foams and method for producing same |
| AU2003221090C1 (en) * | 2002-03-28 | 2009-11-05 | Bridgestone Corporation | Tissue engineering scaffold material, artificial vessel, cuff member and coating for implants |
| AU2003251874A1 (en) * | 2002-07-12 | 2004-02-02 | Dirk R. Albrecht | Three dimensional cell patterned bioploymer scaffolds and method of making the same |
| EP2570440A3 (en) | 2003-02-19 | 2014-06-11 | Orteq B.V. | Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds |
| GB0307011D0 (en) * | 2003-03-27 | 2003-04-30 | Regentec Ltd | Porous matrix |
| US20040197375A1 (en) * | 2003-04-02 | 2004-10-07 | Alireza Rezania | Composite scaffolds seeded with mammalian cells |
| GB0311221D0 (en) * | 2003-05-15 | 2003-06-18 | Orthogem Ltd | Biomaterial |
| AU2004268013B2 (en) * | 2003-08-29 | 2011-05-12 | Mayo Foundation For Medical Education And Research | Hydrogel porogens for fabricating biodegradable scaffolds |
| AU2005212339B2 (en) | 2004-02-06 | 2010-11-25 | Georgia Tech Research Corporation | Load bearing biocompatible device |
| US8002830B2 (en) | 2004-02-06 | 2011-08-23 | Georgia Tech Research Corporation | Surface directed cellular attachment |
| US7446131B1 (en) | 2004-06-10 | 2008-11-04 | The United States Of America As Represented By The Secretary Of Agriculture | Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making |
| US20060024249A1 (en) * | 2004-07-16 | 2006-02-02 | Yelick Pamela C | Methods and compositions for bioengineering a tooth |
| WO2006078320A2 (en) | 2004-08-04 | 2006-07-27 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| PL1789063T3 (pl) * | 2004-09-17 | 2012-05-31 | Hampton Creek Inc | Mięso do spożycia hodowane techniką inżynierii tkankowej i sposób wytwarzania mięsa do spożycia hodowanego techniką inżynierii tkankowej |
| JP5108523B2 (ja) * | 2004-11-12 | 2012-12-26 | メイヨ フオンデーシヨン フオー メデイカル エジユケーシヨン アンド リサーチ | 光架橋性ポリ(カプロラクトンフマレート) |
| ATE540984T1 (de) * | 2004-11-18 | 2012-01-15 | Mayo Foundation | Blockcopolymere aus polycaprolacton und poly (propylenfumarat) |
| US20080206186A1 (en) * | 2005-04-26 | 2008-08-28 | Rimon Therapeutics Ltd. | Pro-Angiogenic Polymer Scaffolds |
| US8912247B2 (en) * | 2005-04-29 | 2014-12-16 | Mayo Foundation For Medical Education And Research | Hydrophilic/hydrophobic polymer networks based on poly(caprolactone fumarate), poly(ethylene glycol fumarate), and copolymers thereof |
| CN100453124C (zh) * | 2006-04-28 | 2009-01-21 | 武汉理工大学 | 多孔、分层、三维空间多级结构的组织支架材料及其制备方法 |
| US8197930B1 (en) | 2007-05-10 | 2012-06-12 | Hrl Laboratories, Llc | Three-dimensional ordered open-cellular structures |
| US8287895B1 (en) | 2008-04-24 | 2012-10-16 | Hrl Laboratories, Llc | Three-dimensional biological scaffold compromising polymer waveguides |
| US8048857B2 (en) * | 2006-12-19 | 2011-11-01 | Warsaw Orthopedic, Inc. | Flowable carrier compositions and methods of use |
| US20080177378A1 (en) * | 2007-01-19 | 2008-07-24 | Civention Ag | Partially bioabsorbable implant |
| US8092626B2 (en) * | 2007-03-12 | 2012-01-10 | University Of Washington | Foaming methods for making cellular thermoplastic materials |
| US20090069904A1 (en) * | 2007-09-12 | 2009-03-12 | Applied Medical Research | Biomaterial including micropores |
| WO2009085952A1 (en) | 2007-12-20 | 2009-07-09 | Brookwood Pharmaceuticals, Inc. | Process for preparing microparticles having a low residual solvent volume |
| US9616153B2 (en) | 2008-04-17 | 2017-04-11 | Warsaw Orthopedic, Inc. | Rigid bone graft substitute |
| US20090263507A1 (en) * | 2008-04-18 | 2009-10-22 | Warsaw Orthopedic, Inc. | Biological markers and response to treatment for pain, inflammation, neuronal or vascular injury and methods of use |
| DE102008042401A1 (de) * | 2008-09-26 | 2010-04-08 | Forschungszentrum Karlsruhe Gmbh | Bandscheibenimplantat sowie Verfahren zur Herstellung eines solchen |
| US20110076396A1 (en) * | 2009-09-28 | 2011-03-31 | Limin Guan | Method of forming a calcium phosphate coating within a porous material |
| WO2011150398A1 (en) * | 2010-05-28 | 2011-12-01 | Garnet Biotherapeutics, Inc | Compositions and methods of using living and non-living bioactive devices with components derived from self- renewing colony forming cells cultured and expanded in vitro |
| EP3597226A1 (en) * | 2010-08-10 | 2020-01-22 | Lifecell Corporation | Regenerative tissue scaffolds |
| EP2757964B1 (en) | 2011-05-26 | 2016-05-04 | Cartiva, Inc. | Tapered joint implant and related tools |
| US9415562B1 (en) * | 2011-08-17 | 2016-08-16 | Hrl Laboratories, Llc | Ultra-light micro-lattices and a method for forming the same |
| WO2013082239A1 (en) * | 2011-11-29 | 2013-06-06 | The Regents Of The University Of California | Glucomannan scaffolding for three-dimensional tissue culture and engineering |
| US9539773B2 (en) | 2011-12-06 | 2017-01-10 | Hrl Laboratories, Llc | Net-shape structure with micro-truss core |
| US8485820B1 (en) | 2011-12-22 | 2013-07-16 | Mohamed Ikbal Ali | Devices and methods for enhancing bone growth |
| EP2793962B1 (en) * | 2011-12-23 | 2016-04-27 | Dang Quang Svend Le | Process for modifying the surface morphology of a medical device |
| US9017806B2 (en) | 2012-03-23 | 2015-04-28 | Hrl Laboratories, Llc | High airflow micro-truss structural apparatus |
| KR101304015B1 (ko) * | 2012-06-15 | 2013-09-04 | 단국대학교 산학협력단 | 조직 공학용 하이드로겔-다공성 생체세라믹 융합형 스캐폴드 및 이의 제조방법 |
| CN102961781B (zh) * | 2012-12-18 | 2015-08-05 | 中国科学院长春应用化学研究所 | 一种组织工程支架材料的制备方法 |
| JP6650393B2 (ja) | 2013-06-13 | 2020-02-19 | オージェネシス リミテッド | 細胞の集団、分化転換の方法及びその使用方法 |
| WO2016072017A1 (ja) * | 2014-11-07 | 2016-05-12 | オリンパス株式会社 | 生体組織接合材および生体組織接合方法 |
| MA41296A (fr) | 2014-12-30 | 2017-11-07 | Orgenesis Ltd | Procédés de transdifférenciation et procédés d'utilisation de ceux-ci |
| ES2578705B1 (es) * | 2015-01-28 | 2017-08-04 | Universitat Politècnica De Catalunya | Andamio macroporoso para ingeniería de tejidos óseos, método de diseño tridimensional y aplicaciones |
| US9907663B2 (en) | 2015-03-31 | 2018-03-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
| WO2016161026A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Carpometacarpal (cmc) implants and methods |
| WO2016168363A1 (en) | 2015-04-14 | 2016-10-20 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
| CA2938576A1 (en) * | 2015-08-12 | 2017-02-12 | Howmedica Osteonics Corp. | Methods for forming scaffolds |
| US11331191B2 (en) | 2015-08-12 | 2022-05-17 | Howmedica Osteonics Corp. | Bioactive soft tissue implant and methods of manufacture and use thereof |
| HK1257499A1 (zh) | 2015-11-12 | 2019-10-25 | Graybug Vision, Inc. | 用於治疗的聚集性微粒 |
| EP4356938A3 (en) | 2016-05-02 | 2024-07-24 | Howmedica Osteonics Corp. | Bioactive soft tissue implant and methods of manufacture and use thereof |
| CN109790515B (zh) | 2016-09-27 | 2023-05-05 | 富士胶片株式会社 | 细胞组织的制造方法及多孔膜 |
| EP3600324A4 (en) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS |
| EP3635106A4 (en) | 2017-05-08 | 2021-01-06 | Orgenesis Ltd. | POPULATIONS OF TRANSDIFFERENTIATED CELLS AND THEIR METHODS OF USE |
| AU2018265415A1 (en) | 2017-05-10 | 2019-10-31 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
| KR102198398B1 (ko) * | 2017-09-22 | 2021-01-05 | 고려대학교 산학협력단 | 비용매상분리법을 이용한 다공성 코어-치밀성 쉘 구조형 스캐폴드 제조 기술 |
| US20250101627A1 (en) * | 2022-01-27 | 2025-03-27 | East China University Of Science And Technology | Preparation method of collagen material stripped from electrode and use of collagen material |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US5041138A (en) | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
| DE4120325A1 (de) * | 1991-06-20 | 1992-12-24 | Merck Patent Gmbh | Implantatwerkstoff |
| US5277811A (en) * | 1992-04-14 | 1994-01-11 | Millipore Corporation | Process for forming porous polymeric product from a nonporous polymeric composition and product |
| US5228994A (en) * | 1992-10-13 | 1993-07-20 | Millipore Corporation | Composite microporous membranes |
| US5514378A (en) | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
| US5502092A (en) * | 1994-02-18 | 1996-03-26 | Minnesota Mining And Manufacturing Company | Biocompatible porous matrix of bioabsorbable material |
| GB2301362B (en) | 1995-05-30 | 1999-01-06 | Johnson & Johnson Medical | Absorbable implant materials having controlled porosity |
-
1997
- 1997-11-14 CA CA002221195A patent/CA2221195A1/en not_active Abandoned
-
1998
- 1998-11-13 IL IL13609398A patent/IL136093A0/xx not_active IP Right Cessation
- 1998-11-13 EP EP19980954085 patent/EP1030697B1/en not_active Expired - Lifetime
- 1998-11-13 DE DE1998617600 patent/DE69817600T2/de not_active Expired - Lifetime
- 1998-11-13 ES ES98954085T patent/ES2207861T3/es not_active Expired - Lifetime
- 1998-11-13 JP JP2000520824A patent/JP4636684B2/ja not_active Expired - Fee Related
- 1998-11-13 NZ NZ504973A patent/NZ504973A/en not_active IP Right Cessation
- 1998-11-13 CN CNB988131293A patent/CN1212866C/zh not_active Expired - Fee Related
- 1998-11-13 AU AU11380/99A patent/AU749041B2/en not_active Ceased
- 1998-11-13 CA CA002310070A patent/CA2310070C/en not_active Expired - Fee Related
- 1998-11-13 KR KR1020007005274A patent/KR100664772B1/ko not_active Expired - Fee Related
- 1998-11-13 BR BRPI9814036-1A patent/BR9814036B1/pt not_active IP Right Cessation
- 1998-11-13 AT AT98954085T patent/ATE247994T1/de not_active IP Right Cessation
- 1998-11-13 DK DK98954085T patent/DK1030697T3/da active
- 1998-11-13 US US09/191,107 patent/US6379962B1/en not_active Expired - Lifetime
- 1998-11-13 WO PCT/CA1998/001052 patent/WO1999025391A2/en not_active Ceased
-
2002
- 2002-08-09 AU AU2002300496A patent/AU2002300496B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN1285757A (zh) | 2001-02-28 |
| IL136093A0 (en) | 2001-05-20 |
| DE69817600D1 (de) | 2003-10-02 |
| DE69817600T2 (de) | 2004-06-24 |
| EP1030697A2 (en) | 2000-08-30 |
| NZ504973A (en) | 2003-07-25 |
| JP2001523483A (ja) | 2001-11-27 |
| WO1999025391A2 (en) | 1999-05-27 |
| AU1138099A (en) | 1999-06-07 |
| CA2310070C (en) | 2008-01-08 |
| AU2002300496B2 (en) | 2005-04-21 |
| ATE247994T1 (de) | 2003-09-15 |
| CA2310070A1 (en) | 1999-05-27 |
| US6379962B1 (en) | 2002-04-30 |
| BR9814036B1 (pt) | 2011-07-26 |
| EP1030697B1 (en) | 2003-08-27 |
| WO1999025391A3 (en) | 1999-08-26 |
| KR100664772B1 (ko) | 2007-01-04 |
| KR20010015819A (ko) | 2001-02-26 |
| JP4636684B2 (ja) | 2011-02-23 |
| CN1212866C (zh) | 2005-08-03 |
| CA2221195A1 (en) | 1999-05-14 |
| ES2207861T3 (es) | 2004-06-01 |
| AU749041B2 (en) | 2002-06-20 |
| BR9814036A (pt) | 2000-11-21 |
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