DK1032376T3 - Anvendelse af benzhydrylsulfinylderivater til behandling af søvnighed af medicinal oprindelse - Google Patents
Anvendelse af benzhydrylsulfinylderivater til behandling af søvnighed af medicinal oprindelseInfo
- Publication number
- DK1032376T3 DK1032376T3 DK98955701T DK98955701T DK1032376T3 DK 1032376 T3 DK1032376 T3 DK 1032376T3 DK 98955701 T DK98955701 T DK 98955701T DK 98955701 T DK98955701 T DK 98955701T DK 1032376 T3 DK1032376 T3 DK 1032376T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- sleepiness
- derivatives
- benzhydrylsulfinyl
- medicinal origin
- Prior art date
Links
- 208000032140 Sleepiness Diseases 0.000 title abstract 2
- 206010041349 Somnolence Diseases 0.000 title abstract 2
- -1 benzhydrylsulfinyl Chemical class 0.000 title abstract 2
- 230000037321 sleepiness Effects 0.000 title abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 108010087765 Antipain Proteins 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- SDNYTAYICBFYFH-TUFLPTIASA-N antipain Chemical compound NC(N)=NCCC[C@@H](C=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 SDNYTAYICBFYFH-TUFLPTIASA-N 0.000 abstract 1
- 230000001622 hypnogenic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 229940124583 pain medication Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9714519A FR2771004B1 (fr) | 1997-11-19 | 1997-11-19 | Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse |
| PCT/FR1998/002478 WO1999025329A1 (fr) | 1997-11-19 | 1998-11-19 | Utilisation de derives de benzhydryl sulfinyle pour traiter la somnolence d'origine medicamenteuse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1032376T3 true DK1032376T3 (da) | 2002-08-26 |
Family
ID=9513542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98955701T DK1032376T3 (da) | 1997-11-19 | 1998-11-19 | Anvendelse af benzhydrylsulfinylderivater til behandling af søvnighed af medicinal oprindelse |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6566404B2 (da) |
| EP (1) | EP1032376B1 (da) |
| AT (1) | ATE216879T1 (da) |
| AU (1) | AU743915B2 (da) |
| CA (1) | CA2310141C (da) |
| DE (1) | DE69805202T2 (da) |
| DK (1) | DK1032376T3 (da) |
| ES (1) | ES2177084T3 (da) |
| FR (1) | FR2771004B1 (da) |
| WO (1) | WO1999025329A1 (da) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6346548B1 (en) | 1999-08-16 | 2002-02-12 | Cephalon, Inc. | Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue |
| US6455588B1 (en) | 1999-08-20 | 2002-09-24 | Cephalon, Inc. | Compositions including modafinil for treatment of eating disorders and for appetite stimulation |
| FR2804322B1 (fr) * | 2000-01-31 | 2002-04-19 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un medicament destine a corriger les troubles de la vigilance associes aux myopathies |
| US6670358B2 (en) * | 2000-05-16 | 2003-12-30 | Cephalon, Inc. | Substituted thioacetamides |
| US6492396B2 (en) | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
| MXPA03000747A (es) * | 2000-07-27 | 2003-06-04 | Teva Pharma | Modafinilo cristalino y puro y proceso para prepararlo. |
| IL155322A0 (en) * | 2000-10-11 | 2003-11-23 | Cephalon Inc | Compositions comprising modafinil compounds |
| US6919378B2 (en) | 2000-10-11 | 2005-07-19 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| BR0114814A (pt) * | 2000-10-11 | 2005-01-25 | Cephalon Inc | Composições compreendendo composto de modafinila e seu uso |
| US6489363B2 (en) | 2000-10-11 | 2002-12-03 | Cephalon, Inc. | Pharmaceutical solutions of modafinil compounds |
| US6992219B2 (en) | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
| US20040242568A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| US20040242698A1 (en) * | 2003-05-13 | 2004-12-02 | Cephalon Inc. | Analeptic and antidepressant combinations |
| AR045423A1 (es) * | 2003-05-13 | 2005-10-26 | Cephalon Inc | Combinaciones de analiticos y antidepresivos |
| AR045314A1 (es) * | 2003-05-13 | 2005-10-26 | Cephalon Inc | Composiciones farmaceuticas de analepticos y antidepresivos |
| US20040229941A1 (en) * | 2003-05-13 | 2004-11-18 | Cephalon, Inc. | Analeptic and antidepressant combinations |
| US20040229943A1 (en) * | 2003-05-16 | 2004-11-18 | Cephalon Inc | Analeptic and drug combinations |
| MXPA06001601A (es) | 2003-08-13 | 2006-08-25 | Takeda Pharmaceutical | Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa. |
| US20050065144A1 (en) * | 2003-09-08 | 2005-03-24 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| WO2005026148A1 (en) * | 2003-09-08 | 2005-03-24 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7368591B2 (en) | 2003-09-19 | 2008-05-06 | Cephalon France | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
| CN102079743B (zh) * | 2004-03-15 | 2020-08-25 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
| US7297817B2 (en) | 2004-04-13 | 2007-11-20 | Cephalon France | Thio-substituted arylmethanesulfinyl derivatives |
| US7449481B2 (en) * | 2004-04-13 | 2008-11-11 | Cephalon, Inc. | Thio-substituted biaryl-methanesulfinyl derivatives |
| US7119214B2 (en) | 2004-04-13 | 2006-10-10 | Cephalon France | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives |
| US7314875B2 (en) * | 2004-04-13 | 2008-01-01 | Cephalon, Inc. | Tricyclic aromatic and bis-phenyl sulfinyl derivatives |
| EP1586560A1 (en) | 2004-04-13 | 2005-10-19 | Cephalon, Inc. | Thio-substituted arylmethanesulfinyl derivatives |
| GEP20135791B (en) * | 2005-09-14 | 2013-03-25 | Takeda Pharmaceutical | Use of dipeptidyl peptidase inhibitors |
| NZ566799A (en) * | 2005-09-14 | 2011-04-29 | Takeda Pharmaceutical | Dipeptidyl peptidase inhibitors for treating diabetes |
| WO2007033265A1 (en) * | 2005-09-14 | 2007-03-22 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors for treating diabetis |
| WO2007035629A2 (en) * | 2005-09-16 | 2007-03-29 | Takeda Pharmaceutical Company Limited | Process for the preparation of pyrimidinedione derivatives |
| TW200745079A (en) * | 2005-09-16 | 2007-12-16 | Takeda Pharmaceuticals Co | Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor |
| TW200745080A (en) * | 2005-09-16 | 2007-12-16 | Takeda Pharmaceuticals Co | Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor |
| EP1999108A1 (en) * | 2006-03-28 | 2008-12-10 | Takeda Pharmaceutical Company Limited | Preparation of (r)-3-aminopiperidine dihydrochloride |
| JP2009543803A (ja) * | 2006-07-12 | 2009-12-10 | エラン・ファルマ・インターナショナル・リミテッド | モダフィニルのナノ粒子製剤 |
| PL2073810T3 (pl) * | 2006-09-13 | 2012-01-31 | Takeda Pharmaceuticals Co | Zastosowanie 2-6-(3-amino-piperydyn-1-ylo)-3-metylo-2,4-diokso-3,4-dihydro-2H-pirymidyn-1-ylometylo-4-fluoro-benzonitrylu do leczenia cukrzycy, raka, zaburzeń autoimmunizacyjnych i zakażeń HIV |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) * | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| FR2987267B1 (fr) | 2012-02-28 | 2015-01-16 | Debregeas Et Associes Pharma | Application du modafinil dans le traitement de substitution des cacainomanes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
-
1997
- 1997-11-19 FR FR9714519A patent/FR2771004B1/fr not_active Expired - Fee Related
-
1998
- 1998-11-19 ES ES98955701T patent/ES2177084T3/es not_active Expired - Lifetime
- 1998-11-19 CA CA2310141A patent/CA2310141C/fr not_active Expired - Fee Related
- 1998-11-19 AT AT98955701T patent/ATE216879T1/de active
- 1998-11-19 AU AU12451/99A patent/AU743915B2/en not_active Ceased
- 1998-11-19 WO PCT/FR1998/002478 patent/WO1999025329A1/fr not_active Ceased
- 1998-11-19 EP EP98955701A patent/EP1032376B1/fr not_active Expired - Lifetime
- 1998-11-19 US US09/554,682 patent/US6566404B2/en not_active Expired - Lifetime
- 1998-11-19 DE DE69805202T patent/DE69805202T2/de not_active Expired - Lifetime
- 1998-11-19 DK DK98955701T patent/DK1032376T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE216879T1 (de) | 2002-05-15 |
| US6566404B2 (en) | 2003-05-20 |
| CA2310141A1 (fr) | 1999-05-27 |
| US20030008925A1 (en) | 2003-01-09 |
| CA2310141C (fr) | 2010-04-27 |
| WO1999025329A1 (fr) | 1999-05-27 |
| AU1245199A (en) | 1999-06-07 |
| DE69805202D1 (de) | 2002-06-06 |
| AU743915B2 (en) | 2002-02-07 |
| ES2177084T3 (es) | 2002-12-01 |
| EP1032376A1 (fr) | 2000-09-06 |
| DE69805202T2 (de) | 2002-12-05 |
| EP1032376B1 (fr) | 2002-05-02 |
| FR2771004A1 (fr) | 1999-05-21 |
| FR2771004B1 (fr) | 2000-02-18 |
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