DK105477A - Fremgangsmade til fremstilling af immun- og antiinfektionshjelpestoffer omfattende estere af n-acetyl-muramyl-l-alanyl-d-glutaminsyre og n-acetyl-muramyl-l-alanyl-d-isoglutamin - Google Patents

Fremgangsmade til fremstilling af immun- og antiinfektionshjelpestoffer omfattende estere af n-acetyl-muramyl-l-alanyl-d-glutaminsyre og n-acetyl-muramyl-l-alanyl-d-isoglutamin

Info

Publication number: DK105477A
Authority: DK; Denmark
Prior art keywords: muramyl; acetyl; alanogy; alanyl; immune
Prior art date: 1976-03-10

Application number

DK105477A

Other languages

English (en)

Other versions

DK151813B (da

DK151813C (da

Inventor

F Audibert

L Chedid

P Lefrancier

J Choay

E Lederer

Original Assignee

Anvar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-10

Filing date

1977-03-10

Publication date

1977-09-11

1976-03-10 Priority claimed from FR7606820A external-priority patent/FR2343483A1/fr

1977-01-31 Priority claimed from FR7702646A external-priority patent/FR2369292A1/fr

1977-03-10 Application filed by Anvar filed Critical Anvar

1977-09-11 Publication of DK105477A publication Critical patent/DK105477A/da

1988-01-04 Publication of DK151813B publication Critical patent/DK151813B/da

1988-07-04 Application granted granted Critical

1988-07-04 Publication of DK151813C publication Critical patent/DK151813C/da

Links

GYEVLPNPMOYWPZ-NQYRFPRJSA-N (2R)-2-[[(2S)-2-[acetyl-[(3R,4R,5S,6R)-3-amino-4-[(1R)-1-carboxyethoxy]-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]amino]propanoyl]amino]pentanedioic acid Chemical compound C(C)(=O)N([C@@H](C)C(=O)N[C@H](CCC(=O)O)C(=O)O)C1[C@H](N)[C@@H](O[C@@H](C(=O)O)C)[C@H](O)[C@H](O1)CO GYEVLPNPMOYWPZ-NQYRFPRJSA-N 0.000 title 1
230000002924 anti-infective effect Effects 0.000 title 1
239000000546 pharmaceutical excipient Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Crystallography & Structural Chemistry (AREA)
Mycology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK105477A 1976-03-10 1977-03-10 Analogifremgangsmaade til fremstilling af estere af n-acetyl-muramyl-l-alanyl-d-glutaminsyre og af n-acetyl-muramyl-l-alanyl-d-isoglutamin DK151813C (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
FR7606820		1976-03-10
FR7606820A FR2343483A1 (fr)	1976-03-10	1976-03-10	L'ester methylique de la 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-isoglutamine et le diester methylique de l'acide 2- (2-acetamido-2-deoxy-3-o-d-glucopyranosyl) -d-propionyl-l-alanyl-d-glutamique et medicaments les contenant
GB4559776		1976-11-02
GB4559776		1976-11-02
FR7702646A FR2369292A1 (fr)	1976-11-02	1977-01-31	Agents adjuvants immunit
FR7702646		1977-01-31

Publications (3)

Publication Number	Publication Date
DK105477A true DK105477A (da)	1977-09-11
DK151813B DK151813B (da)	1988-01-04
DK151813C DK151813C (da)	1988-07-04

Family

ID=27250596

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK105477A DK151813C (da)	1976-03-10	1977-03-10	Analogifremgangsmaade til fremstilling af estere af n-acetyl-muramyl-l-alanyl-d-glutaminsyre og af n-acetyl-muramyl-l-alanyl-d-isoglutamin

Country Status (4)

Country	Link
CH (1)	CH619469A5 (da)
DE (1)	DE2710454C2 (da)
DK (1)	DK151813C (da)
NL (1)	NL7702579A (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2420545A1 (fr) *	1978-03-20	1979-10-19	Anvar	Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2442241A2 (fr) *	1978-03-20	1980-06-20	Anvar	Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
US7112564B2 (en) *	2003-04-09	2006-09-26	Zylacta Corporation	Biodegradable glucosaminemuramyl peptides for apoptosis modulation

1977
- 1977-03-10 DE DE2710454A patent/DE2710454C2/de not_active Expired
- 1977-03-10 DK DK105477A patent/DK151813C/da not_active IP Right Cessation
- 1977-03-10 NL NL7702579A patent/NL7702579A/xx not_active Application Discontinuation
- 1977-03-10 CH CH305277A patent/CH619469A5/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK151813B (da)	1988-01-04
DK151813C (da)	1988-07-04
NL7702579A (nl)	1977-09-13
CH619469A5 (en)	1980-09-30
DE2710454C2 (de)	1986-03-27
DE2710454A1 (de)	1977-09-22

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Legal Events

Date	Code	Title	Description
1993-11-22	PBP	Patent lapsed