DK1060183T3 - 5-deoxycytidinderivater - Google Patents

5-deoxycytidinderivater

Info

Publication number
DK1060183T3
DK1060183T3 DK99907492T DK99907492T DK1060183T3 DK 1060183 T3 DK1060183 T3 DK 1060183T3 DK 99907492 T DK99907492 T DK 99907492T DK 99907492 T DK99907492 T DK 99907492T DK 1060183 T3 DK1060183 T3 DK 1060183T3
Authority
DK
Denmark
Prior art keywords
deoxycytidine derivatives
deoxycytidine
derivatives
Prior art date
Application number
DK99907492T
Other languages
English (en)
Inventor
Kazuo Hattori
Tohru Ishikawa
Hideo Ishitsuka
Yasunori Kohchi
Nobuhiro Oikawa
Nobuo Shimma
Hitomi Suda
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1060183T3 publication Critical patent/DK1060183T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99907492T 1998-02-06 1999-02-03 5-deoxycytidinderivater DK1060183T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98102080 1998-02-06
EP98108321 1998-05-07
PCT/EP1999/000710 WO1999040099A1 (en) 1998-02-06 1999-02-03 5'-deoxycytidine derivatives

Publications (1)

Publication Number Publication Date
DK1060183T3 true DK1060183T3 (da) 2003-08-11

Family

ID=26149007

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99907492T DK1060183T3 (da) 1998-02-06 1999-02-03 5-deoxycytidinderivater

Country Status (19)

Country Link
US (1) US6005098A (da)
EP (1) EP1060183B1 (da)
JP (2) JP3625276B2 (da)
KR (1) KR100381516B1 (da)
CN (1) CN1260240C (da)
AR (1) AR014539A1 (da)
AT (1) ATE238335T1 (da)
AU (1) AU757136B2 (da)
BR (1) BR9907672A (da)
CA (1) CA2318848C (da)
CO (1) CO5070642A1 (da)
DE (1) DE69907161T2 (da)
DK (1) DK1060183T3 (da)
ES (1) ES2195543T3 (da)
MA (1) MA26606A1 (da)
PE (1) PE20000244A1 (da)
PT (1) PT1060183E (da)
TR (1) TR200002297T2 (da)
WO (1) WO1999040099A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030119724A1 (en) * 1995-11-22 2003-06-26 Ts`O Paul O.P. Ligands to enhance cellular uptake of biomolecules
EP0882734B1 (en) * 1997-06-02 2009-08-26 F. Hoffmann-La Roche Ag 5'-Deoxy-cytidine derivatives
ES2226647T3 (es) 1999-05-26 2005-04-01 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de vinil pirimidina.
KR100631754B1 (ko) * 2000-08-09 2006-10-09 주식회사 코오롱 Ｎ-알킬옥시카르보닐-5-플루오로사이토신 유도체 및 그의제조방법
CN100406065C (zh) 2000-12-01 2008-07-30 细胞工厂治疗公司 糖基化/半乳糖基化肽、双官能接头和核苷酸单体/多聚体的缀合物以及相关的组合物和使用方法
CN100383128C (zh) * 2004-02-23 2008-04-23 上海迪赛诺医药发展有限公司 N4－氧羰基胞嘧啶衍生物及制备方法与应用
CA2604192A1 (en) * 2005-04-12 2006-10-19 Elan Pharma International Limited Modified release compositions comprising a fluorocytidine derivative for the treatment of cancer
JP6866113B2 (ja) * 2016-11-01 2021-04-28 日本化薬株式会社 カペシタビンを有効成分とする医薬製剤
JP6792418B2 (ja) * 2016-11-08 2020-11-25 日本化薬株式会社 カペシタビンを有効成分とする医薬製剤の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
GB2016921B (en) * 1978-03-27 1982-08-18 Taiho Pharmaceutical Co Ltd Anti cancer compositions containing uracil derivatives
JPS54129131A (en) * 1978-03-27 1979-10-06 Taiho Pharmaceutical Co Ltd Antiimalignant tumor agent composition
US4328229A (en) * 1978-03-29 1982-05-04 Taiho Pharmaceutical Company Limited Anti-cancer composition for delivering 5-fluorouracil to cancer tissues
CA1327358C (en) * 1987-11-17 1994-03-01 Morio Fujiu Fluoro cytidine derivatives
ATE161722T1 (de) * 1990-07-19 1998-01-15 Wellcome Found Enzyminaktivatoren
GB9020930D0 (en) * 1990-09-26 1990-11-07 Wellcome Found Pharmaceutical combinations
CA2087540C (en) * 1991-05-27 1999-01-19 Taiho Pharmaceutical Co., Ltd. Composition, method and kit for potentiating antitumor activity and for curing tumor
AU671491B2 (en) * 1992-12-18 1996-08-29 F. Hoffmann-La Roche Ag N-oxycarbonyl substituted 5'-deoxy-5-fluorcytidines
TW254946B (da) * 1992-12-18 1995-08-21 Hoffmann La Roche
EP0882734B1 (en) * 1997-06-02 2009-08-26 F. Hoffmann-La Roche Ag 5'-Deoxy-cytidine derivatives

Also Published As

Publication number Publication date
MA26606A1 (fr) 2004-12-20
ES2195543T3 (es) 2003-12-01
AU2722799A (en) 1999-08-23
KR20010072543A (ko) 2001-07-31
US6005098A (en) 1999-12-21
EP1060183B1 (en) 2003-04-23
CO5070642A1 (es) 2001-08-28
PE20000244A1 (es) 2000-04-10
ATE238335T1 (de) 2003-05-15
CN1290269A (zh) 2001-04-04
CA2318848C (en) 2008-09-02
JP3625276B2 (ja) 2005-03-02
CA2318848A1 (en) 1999-08-12
KR100381516B1 (ko) 2003-04-23
DE69907161D1 (de) 2003-05-28
DE69907161T2 (de) 2004-02-05
BR9907672A (pt) 2000-11-28
TR200002297T2 (tr) 2000-12-21
EP1060183A1 (en) 2000-12-20
AU757136B2 (en) 2003-02-06
PT1060183E (pt) 2003-08-29
WO1999040099A1 (en) 1999-08-12
JP2002502857A (ja) 2002-01-29
AR014539A1 (es) 2001-02-28
JP2004339230A (ja) 2004-12-02
CN1260240C (zh) 2006-06-21

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