DK107100C - Fremgangsmåde til fremstilling af fluorsubstituerede 7-nitro-1,4-benzodiazepinforbindelser eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af fluorsubstituerede 7-nitro-1,4-benzodiazepinforbindelser eller syreadditionssalte deraf.Info
- Publication number
- DK107100C DK107100C DK111363A DK111363A DK107100C DK 107100 C DK107100 C DK 107100C DK 111363 A DK111363 A DK 111363A DK 111363 A DK111363 A DK 111363A DK 107100 C DK107100 C DK 107100C
- Authority
- DK
- Denmark
- Prior art keywords
- fluorosubstituted
- nitro
- preparation
- acid addition
- addition salts
- Prior art date
Links
- KAOFUQSZAJJSCB-UHFFFAOYSA-N 7-nitro-1h-1,4-benzodiazepine Chemical class N1C=CN=CC2=CC([N+](=O)[O-])=CC=C21 KAOFUQSZAJJSCB-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18144062A | 1962-03-21 | 1962-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK107100C true DK107100C (da) | 1967-04-24 |
Family
ID=22664289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK111363A DK107100C (da) | 1962-03-21 | 1963-03-11 | Fremgangsmåde til fremstilling af fluorsubstituerede 7-nitro-1,4-benzodiazepinforbindelser eller syreadditionssalte deraf. |
Country Status (7)
| Country | Link |
|---|---|
| BR (1) | BR6347165D0 (da) |
| CH (3) | CH454888A (da) |
| DE (1) | DE1445872A1 (da) |
| DK (1) | DK107100C (da) |
| ES (1) | ES286241A1 (da) |
| GB (1) | GB1039372A (da) |
| SE (1) | SE312808B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2529203A1 (fr) * | 1982-06-24 | 1983-12-30 | Fabre Sa Pierre | Procede industriel d'obtention et de purification de flunitrazepam de qualite pharmaceutique |
-
1963
- 1963-02-12 CH CH1719566A patent/CH454888A/de unknown
- 1963-02-12 CH CH175363A patent/CH441342A/de unknown
- 1963-02-12 CH CH1719666A patent/CH455814A/de unknown
- 1963-02-15 DE DE19631445872 patent/DE1445872A1/de active Pending
- 1963-02-22 BR BR14716563A patent/BR6347165D0/pt unknown
- 1963-03-01 GB GB823763A patent/GB1039372A/en not_active Expired
- 1963-03-11 DK DK111363A patent/DK107100C/da active
- 1963-03-20 ES ES286241A patent/ES286241A1/es not_active Expired
- 1963-03-20 SE SE303663A patent/SE312808B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH455814A (de) | 1968-05-15 |
| SE312808B (da) | 1969-07-28 |
| CH441342A (de) | 1967-08-15 |
| BR6347165D0 (pt) | 1973-07-19 |
| CH454888A (de) | 1968-04-30 |
| ES286241A1 (es) | 1963-11-16 |
| GB1039372A (en) | 1966-08-17 |
| DE1445872A1 (de) | 1969-04-10 |
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