DK107790A - Cyclopeptidderivater, der kan anvendes som selektive inhibitorer af proteaser med aktiv serin - Google Patents

Cyclopeptidderivater, der kan anvendes som selektive inhibitorer af proteaser med aktiv serin Download PDF

Info

Publication number: DK107790A
Authority: DK; Denmark
Prior art keywords: proteas; serin; active; selective inhibitors; derivatives used
Prior art date: 1988-09-02

Application number

DK107790A

Other languages

English (en)

Other versions

DK107790D0 (da

Inventor

Michel Wakselman

Original Assignee

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-02

Filing date

1990-05-01

Publication date

1990-07-02

1990-05-01 Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient

1990-05-01 Publication of DK107790D0 publication Critical patent/DK107790D0/da

1990-07-02 Publication of DK107790A publication Critical patent/DK107790A/da

Links

MTCFGRXMJLQNBG-UHFFFAOYSA-N serine Chemical compound OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 title 2
102000001189 Cyclic Peptides Human genes 0.000 title 1
108010069514 Cyclic Peptides Proteins 0.000 title 1
241000208465 Proteaceae Species 0.000 title 1
229940124639 Selective inhibitor Drugs 0.000 title 1
241001522306 Serinus serinus Species 0.000 title 1
235000019419 proteases Nutrition 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK107790A 1988-09-02 1990-05-01 Cyclopeptidderivater, der kan anvendes som selektive inhibitorer af proteaser med aktiv serin DK107790A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8811528A FR2636066B1 (fr)	1988-09-02	1988-09-02	Derives de cyclopeptides, utilisables comme inhibiteurs selectifs vis-a-vis de proteases a serine active
PCT/FR1989/000435 WO1990002750A1 (fr)	1988-09-02	1989-08-31	Derives de cyclopeptides, utilisables comme inhibiteurs selectifs, vis-a-vis de proteases a serine active

Publications (2)

Publication Number	Publication Date
DK107790D0 DK107790D0 (da)	1990-05-01
DK107790A true DK107790A (da)	1990-07-02

Family

ID=9369677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK107790A DK107790A (da)	1988-09-02	1990-05-01	Cyclopeptidderivater, der kan anvendes som selektive inhibitorer af proteaser med aktiv serin

Country Status (8)

Country	Link
US (1)	US5138035A (da)
EP (1)	EP0357510A1 (da)
JP (1)	JPH03502102A (da)
AU (1)	AU626192B2 (da)
DK (1)	DK107790A (da)
FR (1)	FR2636066B1 (da)
OA (1)	OA09448A (da)
WO (1)	WO1990002750A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2636066B1 (fr) *	1988-09-02	1991-10-25	Centre Nat Rech Scient	Derives de cyclopeptides, utilisables comme inhibiteurs selectifs vis-a-vis de proteases a serine active
WO1992002822A1 (en) *	1990-08-06	1992-02-20	Cetus Corporation	Methods for the identification of cytokine convertase inhibitors
US5635477A (en) *	1991-09-30	1997-06-03	The Dupont Merck Pharmaceutical Company	Cyclic compounds useful as inhibitors of platelet glycoprotein IIB/IIIA
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
AU6415894A (en) *	1993-03-29	1994-10-24	Du Pont Merck Pharmaceutical Company, The	Cyclic compounds useful as inhibitors of platelet glycoprotein iib/iiia
JPH08509708A (ja) *	1993-03-29	1996-10-15	ザ・デュポン・メルク・ファーマシュウティカル・カンパニー	血小板糖蛋白▲ＩＩ▼ｂ／▲ＩＩＩ▼ａ抑制剤の調製のための新規な方法および中間体化合物
US5516889A (en) *	1993-06-21	1996-05-14	University Technologies International, Inc.	Synthetic thrombin receptor peptides
US6251861B1 (en)	1996-06-27	2001-06-26	Takeda Chemical Industries, Ltd.	Treatment of cerebral infarction using cyclic hexapeptides
DE19942624A1 (de) *	1999-08-28	2001-03-08	Chemotopix Gmbh	Verfahren zur Herstellung von zyklischen Peptidomimetika

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2636066B1 (fr) *	1988-09-02	1991-10-25	Centre Nat Rech Scient	Derives de cyclopeptides, utilisables comme inhibiteurs selectifs vis-a-vis de proteases a serine active

1988
- 1988-09-02 FR FR8811528A patent/FR2636066B1/fr not_active Expired - Lifetime
1989
- 1989-08-31 JP JP1509620A patent/JPH03502102A/ja active Pending
- 1989-08-31 AU AU42271/89A patent/AU626192B2/en not_active Ceased
- 1989-08-31 WO PCT/FR1989/000435 patent/WO1990002750A1/fr not_active Ceased
- 1989-08-31 EP EP89402377A patent/EP0357510A1/fr not_active Withdrawn
1990
- 1990-04-24 OA OA59782A patent/OA09448A/xx unknown
- 1990-05-01 DK DK107790A patent/DK107790A/da not_active Application Discontinuation
- 1990-06-01 US US07/477,820 patent/US5138035A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH03502102A (ja)	1991-05-16
FR2636066A1 (fr)	1990-03-09
AU626192B2 (en)	1992-07-23
WO1990002750A1 (fr)	1990-03-22
AU4227189A (en)	1990-04-02
OA09448A (fr)	1992-10-15
US5138035A (en)	1992-08-11
DK107790D0 (da)	1990-05-01
EP0357510A1 (fr)	1990-03-07
FR2636066B1 (fr)	1991-10-25

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Legal Events

Date	Code	Title	Description
1994-04-25	AHB	Application shelved due to non-payment