DK1087973T3 - Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt - Google Patents

Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt

Info

Publication number
DK1087973T3
DK1087973T3 DK99927950T DK99927950T DK1087973T3 DK 1087973 T3 DK1087973 T3 DK 1087973T3 DK 99927950 T DK99927950 T DK 99927950T DK 99927950 T DK99927950 T DK 99927950T DK 1087973 T3 DK1087973 T3 DK 1087973T3
Authority
DK
Denmark
Prior art keywords
drug
imidazotriazolopyrimidines
antagonist effect
adenosine antagonist
radicals
Prior art date
Application number
DK99927950T
Other languages
English (en)
Inventor
Stefan Blech
Adrian Carter
Wolfram Gaida
Matthias Hoffmann
Christopher John Montagu Meade
Gerald Pohl
Ulrike Kuefner-Muehl
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1087973T3 publication Critical patent/DK1087973T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99927950T 1998-06-16 1999-06-11 Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt DK1087973T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19826843A DE19826843A1 (de) 1998-06-16 1998-06-16 Neue Imidazotriazolopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP1999/004017 WO1999065912A1 (de) 1998-06-16 1999-06-11 Imidazotriazolopyrimidine als arzneimittel mit adenosinantagonistischer wirkung

Publications (1)

Publication Number Publication Date
DK1087973T3 true DK1087973T3 (da) 2003-02-24

Family

ID=7871072

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99927950T DK1087973T3 (da) 1998-06-16 1999-06-11 Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt

Country Status (9)

Country Link
EP (1) EP1087973B1 (da)
JP (1) JP4567883B2 (da)
AT (1) ATE230748T1 (da)
AU (1) AU4511299A (da)
CA (1) CA2327395C (da)
DE (2) DE19826843A1 (da)
DK (1) DK1087973T3 (da)
ES (1) ES2186369T3 (da)
WO (1) WO1999065912A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417190B1 (en) 1998-12-17 2002-07-09 Boehringer Ingelheim Pharma Kg Tricyclic nitrogen heterocycles as PDE IV inhibitors
DE19858331A1 (de) * 1998-12-17 2000-06-21 Boehringer Ingelheim Pharma Tricyclische Stickstoffheterocyclen als PDE IV Inhibitoren
CL2004000847A1 (es) * 2003-04-23 2005-03-11 Schering Corp Compuestos derivados de 2-alquinil o 2-alquenil-5amino-pirazolo-[4,3-e]-1,2,4-triazolo[1,5-]pirimidina; composicion farmaceutica, y uso en el tratamiento de enfermedades del sistema nervioso central o un accidente cerebrovascular tal como depresion,
US7071333B2 (en) 2003-07-30 2006-07-04 Bristol-Myers Squibb Company Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
CA3087655A1 (en) * 2018-01-04 2019-07-11 Impetis Biosciences Ltd. Tricyclic compounds, compositions and medicinal applications thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612331B2 (en) * 1986-09-30 1991-07-11 Ciba-Geigy Ag 2-substituted-e-fused-(1,2,4)triazolo(1,5-c)pyrimidines pharmaceutical compositions
DE19629378A1 (de) * 1996-07-20 1998-01-29 Boehringer Ingelheim Kg Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE19826843A1 (de) 1999-12-23
EP1087973B1 (de) 2003-01-08
EP1087973A1 (de) 2001-04-04
AU4511299A (en) 2000-01-05
ATE230748T1 (de) 2003-01-15
DE59903977D1 (de) 2003-02-13
JP4567883B2 (ja) 2010-10-20
JP2002518396A (ja) 2002-06-25
CA2327395C (en) 2008-05-13
WO1999065912A1 (de) 1999-12-23
ES2186369T3 (es) 2003-05-01
CA2327395A1 (en) 1999-12-23

Similar Documents

Publication Publication Date Title
NO20006323D0 (no) Glykopeptidderivater og farmasöytiske sammensetninger som inneholder disse
DK1200418T3 (da) Nematodicide trifluorbutener
NO20020687D0 (no) 3(5)-ureidopyrazolderivater, fremgangsmåte for fremstilling av disse og deres anvendelse som antitumormidler
ATE296826T1 (de) Pyrazolo(1,5)pyridinderivate
NO20012058L (no) 2-ureido-tiazolderivater, fremgangsmåte for deres fremstilling og anvendelse som antitumormidler
NO20012057D0 (no) 2-amino-tiazolderivater, fremgangsmåte for deres fremstilling og anvendelse som antitumormidler
AU2795000A (en) Epothilone derivatives and their use as antitumor agents
DK1202733T3 (da) 3(5)-amino-pyrazolderivater, fremgangsmåde til deres fremstilling og deres anvendelse som antitumormidler
MY138239A (en) Nitrogen containing heterobicycles as factor xa inhibitors
EP1442016A4 (en) 1H-INDOLDERIVATE AS HIGH-DETECTIVE CYCLOOXYGENASE-2 INHIBITORS
HUP0301320A2 (hu) Glikopeptid-foszfonát-származékok
DE60112272D1 (de) Imidazopyridin-derivate
TR200002480T2 (tr) İzaşemi tedavisi için guanidin türevleri
DK0977741T3 (da) Substituerede phenylderivater, deres fremstilling og anvendelse
ATE300541T1 (de) Pyrazolopyridinderivate
HUP0103203A2 (hu) Azaadamantánszármazékok és ezeket tartalmazó gyógyszerkészítmények
MXPA05005198A (es) Derivados de imidazoquinolina, como ligandos del receptor a3 de adenosina.
DK1056771T3 (da) Streptograminderivater, deres fremstilling og præparater, der indeholder dem
ATE259813T1 (de) Triazolopyrimidinderivate
DK1087973T3 (da) Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt
ATE274515T1 (de) Pyrazolopyridinderivate
MXPA03010259A (es) Nuevos derivados de 5-tio-ss-d-xilopiranosida, procedimiento de preparacion, composiciones farmaceuticas que los contienen y el uso terapeutico de los mismos.
BRPI0415038A (pt) derivados de imidazo (4,5-b) piridina como inibidores sem ser da sintase que podem ser induzidos
SE9803107D0 (sv) Novel Compunds
SE9803277D0 (sv) Novel compounds