DK1088228T3 - Bruskresorptionsassays - Google Patents

Bruskresorptionsassays

Info

Publication number
DK1088228T3
DK1088228T3 DK99930368T DK99930368T DK1088228T3 DK 1088228 T3 DK1088228 T3 DK 1088228T3 DK 99930368 T DK99930368 T DK 99930368T DK 99930368 T DK99930368 T DK 99930368T DK 1088228 T3 DK1088228 T3 DK 1088228T3
Authority
DK
Denmark
Prior art keywords
seq
vivo
measurement
antibody
cartilage
Prior art date
Application number
DK99930368T
Other languages
English (en)
Inventor
David R Eyre
Original Assignee
Washington Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington Res Found filed Critical Washington Res Found
Application granted granted Critical
Publication of DK1088228T3 publication Critical patent/DK1088228T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DK99930368T 1998-06-19 1999-06-17 Bruskresorptionsassays DK1088228T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8982398P 1998-06-19 1998-06-19

Publications (1)

Publication Number Publication Date
DK1088228T3 true DK1088228T3 (da) 2006-01-02

Family

ID=22219750

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99930368T DK1088228T3 (da) 1998-06-19 1999-06-17 Bruskresorptionsassays

Country Status (8)

Country Link
US (1) US6255056B1 (da)
EP (1) EP1088228B1 (da)
JP (1) JP4436972B2 (da)
AT (1) ATE302949T1 (da)
AU (1) AU4692199A (da)
DE (2) DE19980834T1 (da)
DK (1) DK1088228T3 (da)
WO (1) WO1999066327A2 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050124071A1 (en) * 2003-09-30 2005-06-09 Kraus Virginia B. Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628027A (en) 1982-05-19 1986-12-09 Molecular Engineering Associates, Ltd. Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
US5316914A (en) 1986-09-04 1994-05-31 Fuji Yakuhin Kogyo Kabushiki Kaisha Method for determining human collagen peptides by way of enzyme immunoassay
US5476765A (en) * 1987-01-09 1995-12-19 United Biomedical, Inc. Synthetic peptide compositions with immunoreactivities to antibodies to HTLV and as vaccines
GB2205643B (en) 1987-05-08 1991-03-13 Farmos Group Limited Type iii collagen degradation assay
US5300434A (en) 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US5320970A (en) 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US4973666A (en) 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US5702909A (en) 1987-11-06 1997-12-30 Washington Research Foundation Methods of detecting collagen type II degradation in vivo
GB8815174D0 (en) 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
GB9105893D0 (en) 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
DE4225038C2 (de) 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
CA2148132A1 (en) 1992-12-04 1994-06-23 Anthony Robin Poole Immunoassay for the measurement of collagen cleavage in cartilage
JPH08505149A (ja) 1992-12-28 1996-06-04 ジェイ. ベイリンク,デビッド 骨再吸収検定法
US6653450B1 (en) 1993-01-28 2003-11-25 Cohesion Technologies, Inc. Mutated recombinant collagens
US5541295A (en) 1993-02-12 1996-07-30 The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations Detection of type II collagen and its peptides
EP0711415B1 (de) 1993-07-28 1998-07-22 Boehringer Mannheim Gmbh Immunoassay zum nachweis von kollagen typ i oder kollagenfragmenten davon
DK104093D0 (da) 1993-09-17 1993-09-17 Osteometer A S Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
JPH10507266A (ja) 1994-10-17 1998-07-14 オステオミーター・ビオ・テク・エー/エス 体液中のコラーゲンの断片化パターンの評価とコラーゲンの代謝に関連する疾患の診断
EP0718309B1 (de) 1994-12-23 1999-04-07 Roche Diagnostics GmbH Antigene und Antikörper zum Nachweis von Kollagen I
US5750647A (en) 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx

Also Published As

Publication number Publication date
ATE302949T1 (de) 2005-09-15
DE69926888T2 (de) 2006-03-30
JP2002518676A (ja) 2002-06-25
WO1999066327A3 (en) 2000-03-09
AU4692199A (en) 2000-01-05
DE69926888D1 (de) 2005-09-29
DE19980834T1 (de) 2001-06-13
EP1088228A2 (en) 2001-04-04
EP1088228B1 (en) 2005-08-24
JP4436972B2 (ja) 2010-03-24
WO1999066327A2 (en) 1999-12-23
US6255056B1 (en) 2001-07-03

Similar Documents

Publication Publication Date Title
ATE221202T1 (de) Bestimmungsverfahren mit oligomerisierten rezeptoren
ATE421692T1 (de) Polyethylenglykol-derivatisierte biomoleküle und deren verwendung in heterogenen nachweisverfahren
DE69833118D1 (de) Immunoassay zum bestimmen von bnp
DK0914344T3 (da) Assay og reagenser til kvantificering af hBNP
IL129535A0 (en) Method for diagnosing bone dysbolism
DK0682257T3 (da) Fremgangsmåder til detektion af collagennedbrydning in vivo
DE59709605D1 (de) Sensitivitätssteigerung bei der immunchemischen Bestimmung eines Analyten
WO2003046140A3 (en) Immunoassay and kit for an early and simulataneous detection of biochemical markers in a patient's sample
ATE320604T1 (de) Homogene nachweisverfahren zur bestimmung von subpopulationen eines analyten
DE3770743D1 (de) Immunometrisches bestimmungsverfahren.
Yoshida et al. A sandwich immunoassay for human prolyl 4-hydroxylase using monoclonal antibody
EP0088974A3 (en) Homogeneous immunoassay with labelled monoclonal anti-analyte
ATE302949T1 (de) Knorpelresorptionsassays
ATE102357T1 (de) Verfahren zur bestimmung von fuer ein antigen klassenspezifischen antikoerpern und dazu geeignetes reagenz.
ATE200353T1 (de) Kompetitiver immuntest unter verwendung komplexierter analytderivate
WO1998029726A3 (en) Method of detecting and determining the concentration of total troponin i in a biological sample
JPH1082784A5 (da)
ES2076221T3 (es) Derivados geminales de difenilo y su uso en inmunoensayos.
YU15401A (sh) Antitela visokog afiniteta
DE69610679D1 (de) Antigen für Enzymimmuntest und Verfahren zur Messung von erythrozytären Antikörpern
SE9900875D0 (sv) Antinuclear antibody assay utilizing stress-treated cells or cell extracts
PT889907E (pt) Anticorpos monoclonais que se ligam a hormona do crescimento humana (hgh)
ATE260936T1 (de) 5-hydroxytryptophol (5-htol) derivate, antikörper,immunoassays und detektion von kürzfristigem alkoholkonsum