DK1098901T3 - Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler - Google Patents

Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Info

Publication number: DK1098901T3
Authority: DK; Denmark
Prior art keywords: pharmaceuticals; processes; preparation; new; radical
Prior art date: 1998-07-21

Application number

DK99932916T

Other languages

Danish (da)

English (en)

Inventor

Jean-Michel Auger

Alexis Denis

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-21

Filing date

1999-07-20

Publication date

2003-05-05

1999-07-20 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2003-05-05 Application granted granted Critical

2003-05-05 Publication of DK1098901T3 publication Critical patent/DK1098901T3/da

Links

ZUGIGWIPEYNYJV-FZWPAWTOSA-N (3r,4s,5r,6s,7s,9r,11r,12r,13s,14r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2r,4r,5s,6s)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ZUGIGWIPEYNYJV-FZWPAWTOSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
239000002253 acid Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
150000007513 acids Chemical class 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK99932916T 1998-07-21 1999-07-20 Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler DK1098901T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9809259A FR2781484B1 (fr)	1998-07-21	1998-07-21	Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
PCT/FR1999/001769 WO2000005239A1 (fr)	1998-07-21	1999-07-20	Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number	Publication Date
DK1098901T3 true DK1098901T3 (da)	2003-05-05

Family

ID=9528813

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99932916T DK1098901T3 (da)	1998-07-21	1999-07-20	Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Country Status (23)

Country	Link
US (1)	US6706692B1 (cs)
EP (1)	EP1098901B1 (cs)
JP (1)	JP4583601B2 (cs)
KR (1)	KR20010071993A (cs)
CN (1)	CN1359386A (cs)
AT (1)	ATE231161T1 (cs)
AU (1)	AU761551B2 (cs)
BR (1)	BRPI9912266B8 (cs)
CA (1)	CA2338172C (cs)
CZ (1)	CZ2001237A3 (cs)
DE (1)	DE69904940T2 (cs)
DK (1)	DK1098901T3 (cs)
EA (1)	EA003776B1 (cs)
ES (1)	ES2188193T3 (cs)
FR (1)	FR2781484B1 (cs)
HU (1)	HUP0103997A3 (cs)
IL (1)	IL140976A0 (cs)
MX (1)	MXPA01000559A (cs)
NO (1)	NO20010332L (cs)
PT (1)	PT1098901E (cs)
TR (1)	TR200100178T2 (cs)
WO (1)	WO2000005239A1 (cs)
ZA (1)	ZA200100566B (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ID30547A (id) *	1999-04-16	2001-12-20	Kosan Biosciences Inc	Zat anti-infeksi makrolida

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5141926A (en) *	1990-04-18	1992-08-25	Abbott Laboratories	Erythromycin derivatives
IL114589A (en) *	1990-11-21	1999-12-22	Roussel Uclaf	Intermediates for the preparation of erythromycin derivatives
FR2692579B1 (fr) *	1992-06-19	1995-06-02	Roussel Uclaf	Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) *	1992-11-05	1994-12-23	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2719587B1 (fr) *	1994-05-03	1996-07-12	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5747466A (en) *	1995-11-08	1998-05-05	Abbott Laboratories	3-deoxy-3-descladinose derivatives of erythromycins A and B
US6274715B1 (en) *	1995-11-08	2001-08-14	Abbott Laboratories	Tricyclic erythromycin derivatives
FR2742757B1 (fr) *	1995-12-22	1998-01-30	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745290B1 (fr) *	1996-02-28	1998-04-03	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP2002502366A (ja) *	1996-05-07	2002-01-22	アボット・ラボラトリーズ	３―デスクラジノース―２，３―無水エリスロマイシン誘導体
FR2751656B1 (fr) *	1996-07-24	1998-10-16	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
IL145976A0 (en) *	1999-04-16	2002-07-25	Ortho Mcneil Pharm Inc	Ketolide antibacterials

1998
- 1998-07-21 FR FR9809259A patent/FR2781484B1/fr not_active Expired - Fee Related
1999
- 1999-07-20 IL IL14097699A patent/IL140976A0/xx unknown
- 1999-07-20 CN CN99808934A patent/CN1359386A/zh active Pending
- 1999-07-20 JP JP2000561195A patent/JP4583601B2/ja not_active Expired - Lifetime
- 1999-07-20 AU AU49132/99A patent/AU761551B2/en not_active Ceased
- 1999-07-20 HU HU0103997A patent/HUP0103997A3/hu unknown
- 1999-07-20 EA EA200100163A patent/EA003776B1/ru not_active IP Right Cessation
- 1999-07-20 KR KR1020017000839A patent/KR20010071993A/ko not_active Ceased
- 1999-07-20 ES ES99932916T patent/ES2188193T3/es not_active Expired - Lifetime
- 1999-07-20 PT PT99932916T patent/PT1098901E/pt unknown
- 1999-07-20 TR TR2001/00178T patent/TR200100178T2/xx unknown
- 1999-07-20 CZ CZ2001237A patent/CZ2001237A3/cs unknown
- 1999-07-20 EP EP99932916A patent/EP1098901B1/fr not_active Expired - Lifetime
- 1999-07-20 AT AT99932916T patent/ATE231161T1/de not_active IP Right Cessation
- 1999-07-20 MX MXPA01000559A patent/MXPA01000559A/es unknown
- 1999-07-20 DE DE69904940T patent/DE69904940T2/de not_active Expired - Lifetime
- 1999-07-20 DK DK99932916T patent/DK1098901T3/da active
- 1999-07-20 US US09/744,320 patent/US6706692B1/en not_active Expired - Lifetime
- 1999-07-20 BR BRPI9912266A patent/BRPI9912266B8/pt not_active IP Right Cessation
- 1999-07-20 CA CA2338172A patent/CA2338172C/fr not_active Expired - Lifetime
- 1999-07-20 WO PCT/FR1999/001769 patent/WO2000005239A1/fr not_active Ceased
2001
- 2001-01-19 ZA ZA200100566A patent/ZA200100566B/xx unknown
- 2001-01-19 NO NO20010332A patent/NO20010332L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP4583601B2 (ja)	2010-11-17
KR20010071993A (ko)	2001-07-31
BRPI9912266B8 (pt)	2021-05-25
NO20010332D0 (no)	2001-01-19
HU0103997D0 (en)	2001-11-28
BR9912266A (pt)	2001-04-17
HUP0103997A3 (en)	2003-11-28
CA2338172C (fr)	2010-09-07
EA003776B1 (ru)	2003-08-28
EP1098901B1 (fr)	2003-01-15
CN1359386A (zh)	2002-07-17
TR200100178T2 (tr)	2002-10-21
DE69904940D1 (de)	2003-02-20
HUP0103997A2 (hu)	2002-02-28
ATE231161T1 (de)	2003-02-15
JP2003534231A (ja)	2003-11-18
DE69904940T2 (de)	2003-08-28
IL140976A0 (en)	2002-02-10
BR9912266B1 (pt)	2013-05-14
MXPA01000559A (es)	2002-04-08
ES2188193T3 (es)	2003-06-16
NO20010332L (no)	2001-03-20
CA2338172A1 (fr)	2000-02-03
FR2781484B1 (fr)	2001-08-10
US6706692B1 (en)	2004-03-16
EP1098901A1 (fr)	2001-05-16
WO2000005239A1 (fr)	2000-02-03
AU4913299A (en)	2000-02-14
ZA200100566B (en)	2002-12-24
CZ2001237A3 (cs)	2001-10-17
EA200100163A1 (ru)	2001-08-27
AU761551B2 (en)	2003-06-05
FR2781484A1 (fr)	2000-01-28
PT1098901E (pt)	2003-06-30

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DK0931788T3 (da)	2002-11-25	Metalloproteasehæmmere
DK0968206T3 (da)	2007-03-26	N-heterocykliske derivater som NOS-inhibitorer
NO20045369L (no)	2004-12-08	Nye, substituerte sulfamatanticonvulsivaderivater
NO20020925D0 (no)	2002-02-26	N-heterosykliske derivater som NOS-inhibitorer
NO20025821L (no)	2003-02-04	2-aminokarbonyl-9H-purinderivater
DK0976748T3 (da)	2004-03-22	Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
ATE90107T1 (de)	1993-06-15	Peptide mit collagenase hemmender wirkung.
MXPA03011722A (es)	2004-03-19	Derivados de piperidina utiles como moduladores de actividad de quimiocina.
DK1265606T3 (da)	2007-02-12	Celleadhæsionsinhibitorer
TW368501B (en)	1999-09-01	7-(2-aminoethyl)-benzothiazolones
ATE87005T1 (de)	1993-04-15	Hydroxamsaeuren.
SE0200919D0 (sv)	2002-03-25	Chemical compounds
NO20054787D0 (no)	2005-10-18	Indenderivater som farmasotiske midler
NO333251B1 (no)	2013-04-22	Fremgangsmate for fremstilling av N-substituerte 2-cyanopyrrolidoner
DE69022370D1 (de)	1995-10-19	Immunstimulierende 6-Aryl-5,6-dihydroimidazo[2,1-b]thiazolderivate.
DK0974598T3 (da)	2011-12-19	Hidtil ukendte erythromcinderivater, fremgangsmådetil fremstillingheraf og anvendelse heraf som lægemidler
MXPA04005837A (es)	2004-09-10	Nuevos derivados de benzotiazina y benzotiadiazina, metodo para su preparacion y composiciones farmaceuticas que los contienen.
ATE420068T1 (de)	2009-01-15	Reverse hydroxamsäurederivate
DK1098901T3 (da)	2003-05-05	Nye 6-deoxyerythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
DE50202381D1 (de)	2005-04-07	Geschützte tyrosinderivate, verfahren zu deren herstellung und deren verwendung zur herstellung von o-(2- ?18 f]-fluorethyl)-l-tyrosin
HRP970279A2 (en)	1998-04-30	Sulfur-containing heterocyclic bradykinin antagonists, processes for their production and use thereof
NO20020886L (no)	2002-02-22	Nye integrin- <alfa>v<beta>3-inhibitorer
NO993124L (no)	1999-08-20	Nye erytromycinderivater, fremgangsmåte for fremstilling av disse samt deres anvendelse som medisiner
MXPA04005839A (es)	2004-09-10	Nuevos compuestos de benzotiazina y benzotiadiazina un proceso para su preparacion y las composiciones farmaceuticas que los contienen.
DK553482A (da)	1983-06-15	Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider