DK1121114T3 - Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser - Google Patents

Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser

Info

Publication number
DK1121114T3
DK1121114T3 DK99941238T DK99941238T DK1121114T3 DK 1121114 T3 DK1121114 T3 DK 1121114T3 DK 99941238 T DK99941238 T DK 99941238T DK 99941238 T DK99941238 T DK 99941238T DK 1121114 T3 DK1121114 T3 DK 1121114T3
Authority
DK
Denmark
Prior art keywords
mania
medication
preparation
treatment
bipolar disorders
Prior art date
Application number
DK99941238T
Other languages
English (en)
Inventor
Atul Chandra Pande
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1121114T3 publication Critical patent/DK1121114T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99941238T 1998-10-16 1999-08-18 Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser DK1121114T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10453598P 1998-10-16 1998-10-16
PCT/US1999/018981 WO2000023067A1 (en) 1998-10-16 1999-08-18 Method for the treatment of mania and bipolar disorder

Publications (1)

Publication Number Publication Date
DK1121114T3 true DK1121114T3 (da) 2007-04-10

Family

ID=22300998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99941238T DK1121114T3 (da) 1998-10-16 1999-08-18 Anvendelse af GABA-analoger til fremstilling af et medikament til behandling af mani og bipolære lidelser

Country Status (16)

Country Link
US (1) US6359005B1 (da)
EP (1) EP1121114B1 (da)
JP (1) JP2002527474A (da)
KR (1) KR100697734B1 (da)
AU (1) AU762599B2 (da)
CA (1) CA2344407C (da)
CY (1) CY1106020T1 (da)
DE (1) DE69934813T2 (da)
DK (1) DK1121114T3 (da)
ES (1) ES2279631T3 (da)
HU (1) HUP0103842A3 (da)
IL (1) IL142225A (da)
NZ (1) NZ510920A (da)
PT (1) PT1121114E (da)
WO (1) WO2000023067A1 (da)
ZA (1) ZA200102561B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001876A (en) 1996-07-24 1999-12-14 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
EP1361847A2 (en) 2000-10-06 2003-11-19 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
AU2002211863A1 (en) 2000-10-06 2002-04-15 Xenoport, Inc. Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
US7022678B2 (en) * 2001-03-30 2006-04-04 Warner-Lambert Company Pregabalin lactose conjugates
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7420002B2 (en) 2001-06-11 2008-09-02 Xenoport Amino acid conjugates providing for sustained systemic concentrations of GABA analogues
MXPA03011566A (es) 2001-06-11 2004-10-28 Xenoport Inc Formas de dosificacion de profarmacos de analogos de gaba administrados oralmente que tienen toxicidad reducida.
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6927036B2 (en) 2002-02-19 2005-08-09 Xero Port, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US7060727B2 (en) 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
MXPA05006209A (es) * 2002-12-13 2005-08-19 Warner Lambert Co Pregabalina y sus derivados para el tratamiento de fibromialgia y otros trastornos relacionados.
WO2005027850A2 (en) 2003-09-17 2005-03-31 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
MXPA06004088A (es) 2003-10-14 2006-06-27 Xenoport Inc Forma cristalina de un analogo del acido gamma-aminobutirico.
DE602005002253T2 (de) * 2004-03-12 2008-05-29 Warner-Lambert Company Llc C1-symmetrische bisphosphinliganden und deren verwendung bei der asymmetrischen synthese von pregabalin
ES2309731T3 (es) * 2004-04-01 2008-12-16 Warner-Lambert Company Llc Preparacion de fosfolanos p-quirogenicos y su uso en sintesis asimetrica.
AP2466A (en) * 2004-06-21 2012-09-17 Warner Lambert Co Preparation of pregabalin and related compounds
EP1811986B1 (en) 2004-11-04 2014-03-26 XenoPort, Inc. Gabapentin prodrug sustained release oral dosage forms
SG176464A1 (en) 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
WO2011141923A2 (en) 2010-05-14 2011-11-17 Lupin Limited Improved synthesis of optically pure (s) - 3-cyano-5-methyl-hexanoic acid alkyl ester, an intermediate of (s)- pregabalin
WO2012059797A1 (en) 2010-11-04 2012-05-10 Lupin Limited Process for synthesis of (s) - pregabalin
KR101035974B1 (ko) * 2011-02-28 2011-05-23 (주) 경화엔지니어링 하수, 폐수 및 침출수 관거용 탈취장치
CA3099775A1 (en) 2018-05-14 2019-11-21 Xgene Pharmaceutical Inc. Process for making 1-(acyloxy)-alkyl-carabmate drug conjugates of naproxen and pregabalin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU94046105A (ru) * 1992-05-20 1997-06-20 Нортвестерн Юниверсити (Us) АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
US5510381A (en) * 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder
NZ334898A (en) * 1996-10-23 2000-09-29 Warner Lambert Co Substituted gamma aminobutyric acids as pharamceutical agents
US6194459B1 (en) * 1997-08-19 2001-02-27 Warner-Lambert Company Methods for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotors stimulants

Also Published As

Publication number Publication date
HUP0103842A2 (hu) 2002-02-28
NZ510920A (en) 2002-08-28
AU762599B2 (en) 2003-06-26
DE69934813D1 (de) 2007-02-22
KR100697734B1 (ko) 2007-03-22
ES2279631T3 (es) 2007-08-16
US6359005B1 (en) 2002-03-19
KR20010080165A (ko) 2001-08-22
HUP0103842A3 (en) 2003-04-28
AU5493099A (en) 2000-05-08
ZA200102561B (en) 2002-09-30
CY1106020T1 (el) 2011-04-06
EP1121114B1 (en) 2007-01-10
JP2002527474A (ja) 2002-08-27
CA2344407A1 (en) 2000-04-27
EP1121114A1 (en) 2001-08-08
WO2000023067A1 (en) 2000-04-27
DE69934813T2 (de) 2007-10-11
IL142225A (en) 2009-09-22
CA2344407C (en) 2007-01-09
PT1121114E (pt) 2007-03-30

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