DK1128835T3 - Cyanocobalamin (vitamin 12)-behandling ved allergisk sygdom - Google Patents

Cyanocobalamin (vitamin 12)-behandling ved allergisk sygdom

Info

Publication number: DK1128835T3
Authority: DK; Denmark
Prior art keywords: vitamin; cyanocobalamin; treatment; allergic disease; allergic
Prior art date: 1998-12-28

Application number

DK99968194T

Other languages

English (en)

Inventor

Hepburn T Armstrong

John A Wise

Ernest T Armstrong

Original Assignee

Cobalis Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-28

Filing date

1999-12-28

Publication date

2006-10-23

1999-12-28 Application filed by Cobalis Corp filed Critical Cobalis Corp

2006-10-23 Application granted granted Critical

2006-10-23 Publication of DK1128835T3 publication Critical patent/DK1128835T3/da

Links

208000026935 allergic disease Diseases 0.000 title abstract 3
RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 title 2
229960002104 cyanocobalamin Drugs 0.000 title 1
235000000639 cyanocobalamin Nutrition 0.000 title 1
239000011666 cyanocobalamin Substances 0.000 title 1
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract 1
206010020751 Hypersensitivity Diseases 0.000 abstract 1
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
229930003779 Vitamin B12 Natural products 0.000 abstract 1
201000009961 allergic asthma Diseases 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
230000007815 allergy Effects 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
239000007937 lozenge Substances 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1
239000011715 vitamin B12 Substances 0.000 abstract 1
235000019163 vitamin B12 Nutrition 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

DK99968194T 1998-12-28 1999-12-28 Cyanocobalamin (vitamin 12)-behandling ved allergisk sygdom DK1128835T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11389698P	1998-12-28	1998-12-28

Publications (1)

Publication Number	Publication Date
DK1128835T3 true DK1128835T3 (da)	2006-10-23

Family

ID=22352184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99968194T DK1128835T3 (da)	1998-12-28	1999-12-28	Cyanocobalamin (vitamin 12)-behandling ved allergisk sygdom

Country Status (13)

Country	Link
US (1)	US6255294B1 (da)
EP (1)	EP1128835B9 (da)
JP (1)	JP2002533399A (da)
AT (1)	ATE330617T1 (da)
AU (1)	AU771728B2 (da)
CA (1)	CA2358054C (da)
CY (1)	CY1107050T1 (da)
DE (1)	DE69932073T2 (da)
DK (1)	DK1128835T3 (da)
ES (1)	ES2268900T3 (da)
MX (1)	MXPA01006297A (da)
PT (1)	PT1128835E (da)
WO (1)	WO2000038696A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6759062B2 (en) *	2000-02-23	2004-07-06	Bioselect Innovations, Inc.	Composition and method for treating the effects of diseases and maladies
US6789546B2 (en) *	2001-06-26	2004-09-14	Technion Research & Development Foundation Ltd.	Filters for preventing or reducing tobacco smoke-associated injury in the aerodigestive tract of a subject
CA2575706A1 (en) *	2004-08-02	2006-02-23	Bebaas, Inc.	Vitamin b12 compositions
WO2007022345A2 (en) *	2005-08-17	2007-02-22	Fleming And Company, Pharmaceuticals	Vitamin b12 nasal spray and method of use
US20130131007A1 (en)	2005-09-07	2013-05-23	Bebaas, Inc.	Vitamin b12 compositions
JP2009507071A (ja) *	2005-09-07	2009-02-19	ビバース、インコーポレイテッド	ビタミンｂ１２組成物
US20070178141A1 (en) *	2005-09-07	2007-08-02	Bebaas, Inc.	Vitamin B12 compositions
US20130084329A1 (en)	2005-12-09	2013-04-04	Hanall Biopharma Co., Ltd.	Compositions for external application, containing adenosylcobalamin for improvement of skin diseases
KR100658436B1 (ko) *	2005-12-09	2006-12-27	한국화학연구원	아데노실코발라민 함유 피부질환 치료용 외용제 조성물
US8586537B2 (en) *	2006-05-25	2013-11-19	Rick Tope	Method for treating minor aphthous ulcers
US20080045448A1 (en) *	2006-08-18	2008-02-21	Alan Robert Vinitsky	Reversing autonomic nervous system dysfunction by potentiating methylation
US20120231089A1 (en) *	2006-08-18	2012-09-13	Alan Robert Vinitsky	Reversing autonomic nervous system dysfunction by potentiating methylation
IL183171A0 (en) *	2007-05-14	2007-09-20	Inna Rvdoy Dr	Use of vitamin b12 for treatment and prevention of mucosal lesions
PL2215047T3 (pl)	2007-11-02	2014-05-30	Emisphere Tech Inc	Sposób leczenia niedoborów witaminy b12
US20090155392A1 (en) *	2007-12-17	2009-06-18	Bret David Nelson	Methods and Systems for Sublingual Guarana Administration
DE102010023324A1 (de) *	2010-06-10	2011-12-15	Thomas Schütz	Verwendung von Corrinoiden zur kosmetischen Anwendung bei gesundem Fell bzw. gesunder Haut, sowie zur kosmetischen Pflege bei Fell- und Hauterkrankungen bei Klein- und Groß-Tieren (warm- und kaltblütig), (z.B. bei Fischen, Vögeln, Pferden, Rindern, Kamelen, Hunden Katzen, Reptilien)
KR20130012709A (ko) *	2011-07-26	2013-02-05	한올바이오파마주식회사	아토피 피부염 치료용 의약 조성물
US9855292B2 (en) *	2013-08-07	2018-01-02	Ernest Timothy Armstrong	Cyanocobalamin, methylcobalamin, and/or adenosylcobalamin to help maintain a pain-free head and pain-free body and provide defense against headaches and body pain
US20150306128A1 (en) *	2014-04-23	2015-10-29	Ernest Timothy Armstrong	Cobalamins to help maintain a normal body weight and a healthy body mass index (bmi) in underweight, overweight and obese humans
WO2016199165A2 (en) *	2015-06-08	2016-12-15	Zim Laboratories Limited	Improved mucosal delivery of vitamin b12
US11318144B2 (en) *	2019-04-12	2022-05-03	LA PharmaTech Inc.	Compositions and methods for treating Alzheimer's disease and Parkinson's disease

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55113721A (en) *	1979-02-27	1980-09-02	Eisai Co Ltd	Immunity regulator
US4432975A (en) *	1981-04-13	1984-02-21	Icn Pharmaceuticals, Inc.	Process for introducing vitamin B-12 into the bloodstream
JPS5821617A (ja) *	1981-07-31	1983-02-08	Sankyo Co Ltd	免疫調節剤
JPS5821618A (ja) *	1981-07-31	1983-02-08	Sankyo Co Ltd	ビタミンｂ配合剤からなる免疫調節剤
US4724231A (en) *	1985-04-16	1988-02-09	Nastech Pharmaceutical, Inc.	Nasel compositions containing vitamin B12
US5135918A (en) *	1988-03-21	1992-08-04	Broncorp	Method for decreasing reaginic antibody levels
US4927850A (en) *	1988-04-08	1990-05-22	Bayless Robert K	Antioxidant compositions and methods for ameliorating inflammatory symptoms of respiratory disease
US5004601A (en) *	1988-10-14	1991-04-02	Zetachron, Inc.	Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
DE69124223T2 (de) *	1990-02-05	1997-04-30	Lifescience Corp	Vitamine und mineralien enthaltende nahrungszusätze
EP0505374B1 (en) *	1990-10-16	1997-04-23	Mayor Pharmaceuticals Laboratories,Inc.	Vitamin-mineral treatment methods and compositions
US5132113A (en) *	1990-10-26	1992-07-21	Maurizio Luca	Nutritional composition containing essential amino acids
JP3157233B2 (ja) *	1991-11-22	2001-04-16	エーザイ株式会社	水溶性薬物を含有した軟カプセル剤
GB9214247D0 (en) *	1992-07-04	1992-08-19	Stephan Peter M	Composition for use as a food or food supplement
WO1994013252A1 (en) *	1992-12-10	1994-06-23	Hemogen, Inc.	Method for stimulating production of heme oxygenase using vitamin b12
US5346701A (en) *	1993-02-22	1994-09-13	Theratech, Inc.	Transmucosal delivery of macromolecular drugs
US5508282C1 (en) *	1993-05-17	2001-01-23	Tulin Silver Jeffrey	Composition and method for treating acute or chronic rhinosinusitis
BE1007839A6 (nl) *	1993-12-20	1995-10-31	Merkus Franciscus W H M Prof	Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.
US6066333A (en) *	1994-09-22	2000-05-23	William Harvey Research Limited	Pharmaceutical control of inflammation
JPH09315987A (ja) *	1996-05-24	1997-12-09	Kureha Chem Ind Co Ltd	泡盛の抗アレルギー有効成分としての利用
CA2306024C (en) *	1997-10-01	2011-04-26	Flemington Pharmaceutical Corporation	Buccal, polar and non-polar spray or capsule

1999
- 1999-12-28 US US09/473,332 patent/US6255294B1/en not_active Expired - Lifetime
- 1999-12-28 WO PCT/US1999/031092 patent/WO2000038696A1/en not_active Ceased
- 1999-12-28 JP JP2000590648A patent/JP2002533399A/ja active Pending
- 1999-12-28 CA CA002358054A patent/CA2358054C/en not_active Expired - Fee Related
- 1999-12-28 MX MXPA01006297A patent/MXPA01006297A/es active IP Right Grant
- 1999-12-28 DK DK99968194T patent/DK1128835T3/da active
- 1999-12-28 DE DE69932073T patent/DE69932073T2/de not_active Expired - Lifetime
- 1999-12-28 ES ES99968194T patent/ES2268900T3/es not_active Expired - Lifetime
- 1999-12-28 PT PT99968194T patent/PT1128835E/pt unknown
- 1999-12-28 EP EP99968194A patent/EP1128835B9/en not_active Expired - Lifetime
- 1999-12-28 AT AT99968194T patent/ATE330617T1/de active
- 1999-12-28 AU AU24865/00A patent/AU771728B2/en not_active Ceased
2006
- 2006-09-20 CY CY20061101346T patent/CY1107050T1/el unknown

Also Published As

Publication number	Publication date
EP1128835A1 (en)	2001-09-05
CA2358054A1 (en)	2000-07-06
CA2358054C (en)	2008-11-18
US6255294B1 (en)	2001-07-03
EP1128835B1 (en)	2006-06-21
PT1128835E (pt)	2006-11-30
AU771728B2 (en)	2004-04-01
CY1107050T1 (el)	2012-09-26
EP1128835B9 (en)	2006-10-11
ATE330617T1 (de)	2006-07-15
AU2486500A (en)	2000-07-31
JP2002533399A (ja)	2002-10-08
WO2000038696A1 (en)	2000-07-06
EP1128835A4 (en)	2002-05-02
DE69932073T2 (de)	2007-02-01
ES2268900T3 (es)	2007-03-16
DE69932073D1 (de)	2006-08-03
MXPA01006297A (es)	2002-06-04

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