DK1140942T3 - Prenyltransferaseinhibitorer - Google Patents

Prenyltransferaseinhibitorer

Info

Publication number: DK1140942T3
Authority: DK; Denmark
Prior art keywords: transferase inhibitors; prenyl transferase; chem; bond; prenyl
Prior art date: 1998-12-31

Application number

DK99968984T

Other languages

English (en)

Inventor

Barry A Morgan

Thomas D Gordon

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-31

Filing date

1999-12-30

Publication date

2004-05-24

1999-12-30 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2004-05-24 Application granted granted Critical

2004-05-24 Publication of DK1140942T3 publication Critical patent/DK1140942T3/da

Links

102000005454 Dimethylallyltranstransferase Human genes 0.000 title 1
108010006731 Dimethylallyltranstransferase Proteins 0.000 title 1
239000003558 transferase inhibitor Substances 0.000 title 1
102000019337 Prenyltransferases Human genes 0.000 abstract 1
108050006837 Prenyltransferases Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000002460 imidazoles Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK99968984T 1998-12-31 1999-12-30 Prenyltransferaseinhibitorer DK1140942T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22442898A	1998-12-31	1998-12-31
US11430198P	1998-12-31	1998-12-31

Publications (1)

Publication Number	Publication Date
DK1140942T3 true DK1140942T3 (da)	2004-05-24

Family

ID=26812031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99968984T DK1140942T3 (da)	1998-12-31	1999-12-30	Prenyltransferaseinhibitorer

Country Status (14)

Country	Link
US (2)	US7361656B2 (da)
EP (2)	EP1382607B1 (da)
AT (2)	ATE261447T1 (da)
AU (1)	AU2717100A (da)
CA (1)	CA2356756A1 (da)
CZ (1)	CZ20012358A3 (da)
DE (2)	DE69915514T2 (da)
DK (1)	DK1140942T3 (da)
ES (2)	ES2328564T3 (da)
HU (1)	HUP0104708A3 (da)
NO (1)	NO321057B1 (da)
PT (1)	PT1140942E (da)
RU (1)	RU2241712C9 (da)
WO (1)	WO2000039130A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI283577B (en) *	1999-10-11	2007-07-11	Sod Conseils Rech Applic	Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
FR2812546B1 (fr) *	2000-08-01	2008-11-21	Sod Conseils Rech Applic	Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
EP1542691B1 (en) *	2002-09-27	2009-01-07	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Composition for the treatment of nasopharyngeal carcinoma and use thereof
ES2546815T3 (es) *	2006-12-15	2015-09-28	Bristol-Myers Squibb Company	Análogos de arilpropilamida, arilacrilamida, arilpropinamida o arilmetilurea como inhibidores del factor XIa
UY32776A (es) *	2009-07-09	2011-02-28	Irm Llc	Compuestos de imidazopirazinas sustituidas para el tratamiento de enfermedades parasitarias,composiciones farmacéuticas que los contienen y aplicación.
EP2508511A1 (en) *	2011-04-07	2012-10-10	Laboratoire Biodim	Inhibitors of viral replication, their process of preparation and their therapeutical uses
AU2013352304C1 (en) *	2012-11-29	2018-03-22	Chemocentryx, Inc.	CXCR7 antagonists
CN106317057B (zh) *	2015-07-02	2019-02-01	北京桦冠医药科技有限公司	具有咪唑并吡嗪类衍生物，其制备及其在医药上的应用
CN110691597A (zh)	2017-04-24	2020-01-14	诺华股份有限公司	2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2093513C1 (ru) *	1989-02-27	1997-10-20	Биокрайст Фармасьютикалз Инк.	Производные 9-деазагуанины или их таутомеры и фармацевтическая композиция, обладающая способностью ингибировать активность пуриннуклеозид фосфорилазы у млекопитающих
RU2092487C1 (ru) *	1992-04-24	1997-10-10	Ньюроджен Корпорейшн	Имидазохиноксалины
US5843941A (en) *	1993-05-14	1998-12-01	Genentech, Inc.	Ras farnesyl transferase inhibitors
US5488109A (en)	1993-11-05	1996-01-30	Dowelanco	5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)--thione compounds and their use in the preparation of and 2-chlorosulfonyl-5-alkoxy[1,2,4]triazolo[1,5-c]-pyrimidine compounds
US5488189A (en) *	1993-12-14	1996-01-30	E. I. Du Pont De Nemours And Company	Process for fluorinated propanes and pentanes
US6673927B2 (en) *	1996-02-16	2004-01-06	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Farnesyl transferase inhibitors
FR2780974B1 (fr) *	1998-07-08	2001-09-28	Sod Conseils Rech Applic	Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique
UA74912C2 (en) *	2001-07-06	2006-02-15	Merck & Co Inc	Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes

1999
- 1999-12-30 ES ES03078315T patent/ES2328564T3/es not_active Expired - Lifetime
- 1999-12-30 DE DE69915514T patent/DE69915514T2/de not_active Expired - Lifetime
- 1999-12-30 DE DE69941307T patent/DE69941307D1/de not_active Expired - Lifetime
- 1999-12-30 CZ CZ20012358A patent/CZ20012358A3/cs unknown
- 1999-12-30 AU AU27171/00A patent/AU2717100A/en not_active Abandoned
- 1999-12-30 EP EP03078315A patent/EP1382607B1/en not_active Expired - Lifetime
- 1999-12-30 CA CA002356756A patent/CA2356756A1/en not_active Abandoned
- 1999-12-30 AT AT99968984T patent/ATE261447T1/de not_active IP Right Cessation
- 1999-12-30 DK DK99968984T patent/DK1140942T3/da active
- 1999-12-30 EP EP99968984A patent/EP1140942B1/en not_active Expired - Lifetime
- 1999-12-30 PT PT99968984T patent/PT1140942E/pt unknown
- 1999-12-30 ES ES99968984T patent/ES2215420T3/es not_active Expired - Lifetime
- 1999-12-30 AT AT03078315T patent/ATE440100T1/de not_active IP Right Cessation
- 1999-12-30 WO PCT/US1999/031302 patent/WO2000039130A2/en not_active Ceased
- 1999-12-30 RU RU2001121317/04A patent/RU2241712C9/ru not_active IP Right Cessation
- 1999-12-30 HU HU0104708A patent/HUP0104708A3/hu unknown
2001
- 2001-06-29 NO NO20013281A patent/NO321057B1/no unknown
2006
- 2006-02-14 US US11/353,518 patent/US7361656B2/en not_active Expired - Fee Related
2007
- 2007-10-30 US US11/929,118 patent/US7691859B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUP0104708A3 (en)	2004-05-28
EP1382607A3 (en)	2004-06-30
NO20013281L (no)	2001-08-29
EP1140942B1 (en)	2004-03-10
HUP0104708A2 (hu)	2002-04-29
NO321057B1 (no)	2006-03-06
ES2328564T3 (es)	2009-11-16
EP1140942A2 (en)	2001-10-10
PT1140942E (pt)	2004-05-31
DE69941307D1 (de)	2009-10-01
US20080176835A1 (en)	2008-07-24
US20060142275A1 (en)	2006-06-29
AU2717100A (en)	2000-07-31
DE69915514T2 (de)	2005-01-05
US7691859B2 (en)	2010-04-06
EP1382607B1 (en)	2009-08-19
RU2241712C9 (ru)	2006-04-20
ATE440100T1 (de)	2009-09-15
CZ20012358A3 (cs)	2002-01-16
EP1382607A2 (en)	2004-01-21
CA2356756A1 (en)	2000-07-06
DE69915514D1 (de)	2004-04-15
NO20013281D0 (no)	2001-06-29
US7361656B2 (en)	2008-04-22
WO2000039130A3 (en)	2000-11-02
WO2000039130A2 (en)	2000-07-06
RU2241712C2 (ru)	2004-12-10
ATE261447T1 (de)	2004-03-15
ES2215420T3 (es)	2004-10-01

Publication	Publication Date	Title
EP0976748A4 (en)	2001-08-08	PYRROLIDIN DERIVATIVES HAVING A PHOSPHOLIPASE A2 INHIBITING EFFECT
DK0931788T3 (da)	2002-11-25	Metalloproteasehæmmere
MY136141A (en)	2008-08-29	Novel hydantoin derivatives and pharmaceutical compositions useful as metalloproteinase inhibitors
DK1022272T3 (da)	2004-09-27	Substituerede, fusionerede, heterocykliske forbindelser
ATE260255T1 (de)	2004-03-15	5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate
DK1265606T3 (da)	2007-02-12	Celleadhæsionsinhibitorer
GB9625045D0 (en)	1997-01-22	Parasiticidal compounds
AU7517400A (en)	2001-04-24	N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
PT918776E (pt)	2004-07-30	Sintese total de acilfulvenos antitumorais
DE69426602D1 (de)	2001-02-22	2,3-diaminopropionsäurederivate
DE69941307D1 (de)	2009-10-01	Prenyl transferasinhibitoren
DK0784055T3 (da)	2003-06-02	Pyrimidinylpyrazolderivater
BRPI0411664A (pt)	2006-08-08	composição oral antiplaca aquosa estável
DE69813554D1 (de)	2003-05-22	Cyclische harnstoff- und lactamderivate von benzo(5,6)cycloheptapyridinen zur verwendung als farnesyl-protein-transferase-hemmer
ATE356112T1 (de)	2007-03-15	Thio-derivate als würzende bestandteile
DE69528984D1 (de)	2003-01-09	Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
BR0101556A (pt)	2003-03-25	Composto heterocìclico