DK1140945T3 - Kondenserede 1,2,4-thiadiazinderivater, deres fremstilling og anvendelse - Google Patents

Kondenserede 1,2,4-thiadiazinderivater, deres fremstilling og anvendelse

Info

Publication number: DK1140945T3
Authority: DK; Denmark
Prior art keywords: condensed; preparation; thiadiazine derivatives; compounds; thiadiazine
Prior art date: 1998-12-18

Application number

DK99959255T

Other languages

English (en)

Inventor

John Bondo Hansen

Flemming Elmelund Nielsen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-18

Filing date

1999-12-15

Publication date

2003-09-15

1999-12-15 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2003-09-15 Application granted granted Critical

2003-09-15 Publication of DK1140945T3 publication Critical patent/DK1140945T3/da

Links

150000008337 1,2,4-thiadiazines Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
210000000748 cardiovascular system Anatomy 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002124 endocrine Effects 0.000 abstract 1
210000005095 gastrointestinal system Anatomy 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000002685 pulmonary effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Hematology (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Pregnancy & Childbirth (AREA)
Dermatology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

DK99959255T 1998-12-18 1999-12-15 Kondenserede 1,2,4-thiadiazinderivater, deres fremstilling og anvendelse DK1140945T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DKPA199801693		1998-12-18
DKPA199900018		1999-01-11
PCT/DK1999/000702 WO2000037474A1 (en)	1998-12-18	1999-12-15	Fused 1,2,4-thiadiazine derivatives, their preparation and use

Publications (1)

Publication Number	Publication Date
DK1140945T3 true DK1140945T3 (da)	2003-09-15

Family

ID=26063128

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99959255T DK1140945T3 (da)	1998-12-18	1999-12-15	Kondenserede 1,2,4-thiadiazinderivater, deres fremstilling og anvendelse

Country Status (18)

Country	Link
EP (2)	EP1338600A1 (da)
JP (1)	JP2002533347A (da)
KR (1)	KR20010086126A (da)
CN (1)	CN1137125C (da)
AT (1)	ATE242254T1 (da)
AU (1)	AU1649900A (da)
BR (1)	BR9916279A (da)
CA (1)	CA2353907A1 (da)
CZ (1)	CZ20011831A3 (da)
DE (1)	DE69908648T2 (da)
DK (1)	DK1140945T3 (da)
ES (1)	ES2200575T3 (da)
HU (1)	HUP0104646A3 (da)
IL (1)	IL143402A0 (da)
NO (1)	NO20012966L (da)
PL (1)	PL348237A1 (da)
PT (1)	PT1140945E (da)
WO (1)	WO2000037474A1 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2001265841A1 (en) *	2000-06-26	2002-01-08	Novo-Nordisk A/S	Use of potassium channel openers for the treatment of insulitis
WO2002000222A1 (en) *	2000-06-26	2002-01-03	Novo Nordisk A/S	Use of potassium channel agonists for the treatment of cancer
WO2002050085A1 (en) *	2000-12-21	2002-06-27	Novo Nordisk A/S	A new process for preparing fused 1,2,4-thiadiazine derivatives
KR100939243B1 (ko)	2001-01-19	2010-01-29	인스티튜트 오브 파마콜로지 앤드 톡시콜로지 아캐더미 오브 밀리터리 메디칼 사이언시스 피.엘.에이. 차이나	포타슘 채널의 기능을 조절하는 아민 유도체, 그의제조방법 및 용도
WO2003031432A1 (en)	2001-10-12	2003-04-17	Novo Nordisk A/S	Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor
AU2002342600A1 (en) *	2001-11-30	2003-06-10	Novo Nordisk A/S	Use of selective potassium channel openers
WO2003045955A1 (en) *	2001-11-30	2003-06-05	Novo Nordisk A/S	Use of selective potassium channel openers
KR101018318B1 (ko)	2001-12-21	2011-03-04	노보 노르디스크 에이/에스	Ｇｋ 활성제로서의 아미드 유도체
WO2003105896A1 (en) *	2002-06-14	2003-12-24	Novo Nordisk A/S	Combined use of a modulator of cd3 and a beta cell resting compound
CA2744893A1 (en)	2002-06-27	2004-01-08	Novo Nordisk A/S	Aryl carbonyl derivatives as glucokinase activators
WO2004005299A1 (en) *	2002-07-04	2004-01-15	Novo Nordisk A/S	Polymorphic forms of a 4h-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivative
JP2007532471A (ja)	2003-09-30	2007-11-15	ノボ　ノルディスク　アクティーゼルスカブ	新規メラノコルチンレセプターアゴニスト
WO2005056036A2 (en)	2003-12-09	2005-06-23	Novo Nordisk A/S	Regulation of food preference using glp-1 agonists
BRPI0506662B8 (pt)	2004-01-06	2021-05-25	Novo Nordisk As	compostos ativadores de glucoquinase
US8410047B2 (en)	2004-06-11	2013-04-02	Novo Nordisk A/S	Counteracting drug-induced obesity using GLP-1 agonists
JP4874989B2 (ja)	2004-11-22	2012-02-15	ノヴォノルディスクアー／エス	可溶性で安定なインスリン含有調合物
AU2005311269B2 (en)	2004-12-03	2011-11-10	Transtech Pharma, Inc.	Heteroaromatic glucokinase activators
ES2435522T3 (es)	2005-02-02	2013-12-20	Novo Nordisk A/S	Derivados de insulina
WO2006082204A1 (en)	2005-02-02	2006-08-10	Novo Nordisk A/S	Insulin derivatives
EP1879567A1 (en)	2005-04-28	2008-01-23	Pfizer Limited	Amino acid derivatives
CN103110635A (zh)	2005-07-04	2013-05-22	海波因特制药有限责任公司	组胺h3受体拮抗剂
JP4960355B2 (ja)	2005-07-14	2012-06-27	ノボ・ノルデイスク・エー／エス	ウレア型グルコキナーゼ活性化剤
ES2426345T3 (es)	2005-07-20	2013-10-22	Eli Lilly And Company	Compuesto unidos en posición 1-amino
CN101312940B (zh)	2005-11-17	2012-11-14	伊莱利利公司	胰高血糖素受体拮抗剂、制备和治疗用途
NZ570524A (en)	2006-03-28	2011-08-26	High Point Pharmaceuticals Llc	Benzothiazoles having histamine H3 receptor activity
CN100500672C (zh) *	2006-04-20	2009-06-17	山东大学	N1,N3-二取代噻吩并[3,2-e][2,1,3]噻二嗪-2,2,4-三酮类衍生物与应用
ATE538116T1 (de)	2006-05-29	2012-01-15	High Point Pharmaceuticals Llc	3-(1,3-benyodioxol-5-yl)-6- (4- cyclopropylpiperazin-1-yl)-pyridazin, dessen salze und solvate und dessen verwendung als histamin-h3-rezeptorantagonist
CA2669874A1 (en)	2006-11-15	2008-05-22	High Point Pharmaceuticals, Llc	Novel 2-(2-hydroxyphenyl) benzothiadiazines useful for treating obesity and diabetes
AU2008204530B2 (en)	2007-01-11	2013-08-01	Vtv Therapeutics Llc	Urea glucokinase activators
BR112012021231A2 (pt)	2010-02-26	2015-09-08	Basf Plant Science Co Gmbh	método para acentuar o rendimento em plantas, planta, construto, uso de um construto, método para a produção de uma planta transgênica, partes coletáveis de uma planta, produtos derivados de uma planta, uso de um ácido nucleíco e método para a produção de um produto
EP2539364A1 (en)	2010-02-26	2013-01-02	Novo Nordisk A/S	Peptides for treatment of obesity
KR20130018410A (ko)	2010-03-26	2013-02-21	노보 노르디스크 에이/에스	새로운 글루카곤 유사체
RU2013145013A (ru)	2011-03-28	2015-05-10	Ново Нордиск А/С	Новые аналоги глюкагона
MX354705B (es)	2011-09-23	2018-03-16	Novo Nordisk As	Analogos de glucagon novedosos.
US9867869B2 (en)	2012-12-12	2018-01-16	Massachusetts Institute Of Technology	Insulin derivatives for diabetes treatment
BR112015025464A2 (pt)	2013-04-18	2017-10-10	Novo Nordisk As	coagonistas do receptor de glp-1/glucagon estáveis, prolongados para uso médico
JP2017525656A (ja)	2014-06-04	2017-09-07	ノヴォノルディスクアー／エス	医療用のｇｌｐ−１／グルカゴン受容体コアゴニスト
US10238743B2 (en)	2014-10-03	2019-03-26	Merck Sharp & Dohme Corp.	C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use
US20200223889A1 (en)	2017-03-15	2020-07-16	Novo Nordisk A/S	Bicyclic Compounds Capable of Binding to Melanocortin 4 Receptor
WO2019219714A1 (en)	2018-05-15	2019-11-21	Novo Nordisk A/S	Compounds capable of binding to melanocortin 4 receptor
WO2020053414A1 (en)	2018-09-14	2020-03-19	Novo Nordisk A/S	Bicyclic compounds capable of acting as melanocortin 4 receptor agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ220498A3 (cs) *	1996-01-17	1998-11-11	Novo Nordisk A/S	Deriváty 1,2,4-thiadiazinu a 1,4-thiazinu, příprava a použití
AU757693B2 (en) *	1997-07-16	2003-03-06	Novo Nordisk A/S	Fused 1,2,4-thiadiazine derivatives, their preparation and use

1999
- 1999-12-15 KR KR1020017007713A patent/KR20010086126A/ko not_active Withdrawn
- 1999-12-15 HU HU0104646A patent/HUP0104646A3/hu unknown
- 1999-12-15 JP JP2000589544A patent/JP2002533347A/ja active Pending
- 1999-12-15 DE DE69908648T patent/DE69908648T2/de not_active Expired - Fee Related
- 1999-12-15 DK DK99959255T patent/DK1140945T3/da active
- 1999-12-15 IL IL14340299A patent/IL143402A0/xx unknown
- 1999-12-15 PL PL99348237A patent/PL348237A1/xx not_active Application Discontinuation
- 1999-12-15 CN CNB998144894A patent/CN1137125C/zh not_active Expired - Fee Related
- 1999-12-15 EP EP03006331A patent/EP1338600A1/en not_active Withdrawn
- 1999-12-15 EP EP99959255A patent/EP1140945B1/en not_active Expired - Lifetime
- 1999-12-15 ES ES99959255T patent/ES2200575T3/es not_active Expired - Lifetime
- 1999-12-15 AU AU16499/00A patent/AU1649900A/en not_active Abandoned
- 1999-12-15 BR BR9916279-2A patent/BR9916279A/pt not_active IP Right Cessation
- 1999-12-15 WO PCT/DK1999/000702 patent/WO2000037474A1/en not_active Ceased
- 1999-12-15 AT AT99959255T patent/ATE242254T1/de active
- 1999-12-15 PT PT99959255T patent/PT1140945E/pt unknown
- 1999-12-15 CA CA002353907A patent/CA2353907A1/en not_active Abandoned
- 1999-12-15 CZ CZ20011831A patent/CZ20011831A3/cs unknown
2001
- 2001-06-15 NO NO20012966A patent/NO20012966L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0104646A3 (en)	2004-05-28
CA2353907A1 (en)	2000-06-29
AU1649900A (en)	2000-07-12
EP1338600A1 (en)	2003-08-27
ATE242254T1 (de)	2003-06-15
EP1140945B1 (en)	2003-06-04
IL143402A0 (en)	2002-04-21
JP2002533347A (ja)	2002-10-08
HUP0104646A2 (hu)	2002-04-29
CN1137125C (zh)	2004-02-04
BR9916279A (pt)	2001-10-16
CZ20011831A3 (cs)	2001-10-17
KR20010086126A (ko)	2001-09-07
WO2000037474A1 (en)	2000-06-29
DE69908648D1 (de)	2003-07-10
PL348237A1 (en)	2002-05-20
NO20012966D0 (no)	2001-06-15
PT1140945E (pt)	2003-10-31
ES2200575T3 (es)	2004-03-01
DE69908648T2 (de)	2004-05-13
NO20012966L (no)	2001-06-15
CN1330655A (zh)	2002-01-09
EP1140945A1 (en)	2001-10-10

Publication	Publication Date	Title
NO20012966L (no)	2001-06-15	Kondenserte 1,2,4-tiadiazinderivater, deres fremstilling og anvendelse
ATE361288T1 (de)	2007-05-15	N-(3,-dimethylindolin-6-yl)ä2-ä(4-
ATE315938T1 (de)	2006-02-15	4'-substituierte nukleoside zur behandlung von hepatitis-c-virus-vermittelten erkrankungen
LU92146I2 (fr)	2013-04-05	Dasatinib et ses sels pharmaceutiquement acceptables
ATE245152T1 (de)	2003-08-15	Dioxocyclopentylhydroxamsäure
PL365026A1 (en)	2004-12-27	Pyrazole derivatives for treating hiv
PT1259489E (pt)	2006-08-31	Compostos azapoliciclicos condensados con arilo.
DK0807633T3 (da)	2002-11-25	Hidtil ukendte 2,3-disubstituerede-(5,6)-heteroarylkondenserede pyrimidin-4-oner
NO983286L (no)	1998-09-16	Kondenserte 1,2,4-tiadiazin- og kondenserte 1,4-tiazinderivater, deres fremstilling og anvendelse
NO995431D0 (no)	1999-11-05	Substituerte 3,3-diamino-2-propennitriler, deres fremstilling og anvendelse
CA2474511A1 (en)	2003-09-04	Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders
DK0434057T3 (da)	1996-11-25	Indocarbazol-derivater, fremgangsmåder til deres fremstilling og deres anvendelse
NO20030802L (no)	2003-04-23	Aminoalkoksybenzoyl-benzofuran- eller benzotiofenderivater, fremgangsmåte for deres fremstilling og preparater inneholdende de samme
DE59909607D1 (de)	2004-07-01	Tan-1057 derivate
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