DK1144006T3 - Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil - Google Patents

Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil

Info

Publication number
DK1144006T3
DK1144006T3 DK99966466T DK99966466T DK1144006T3 DK 1144006 T3 DK1144006 T3 DK 1144006T3 DK 99966466 T DK99966466 T DK 99966466T DK 99966466 T DK99966466 T DK 99966466T DK 1144006 T3 DK1144006 T3 DK 1144006T3
Authority
DK
Denmark
Prior art keywords
hiv
antibodies
preparations
fusion
binding
Prior art date
Application number
DK99966466T
Other languages
English (en)
Inventor
William C Olson
Paul J Maddon
Original Assignee
Progenics Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharm Inc filed Critical Progenics Pharm Inc
Application granted granted Critical
Publication of DK1144006T3 publication Critical patent/DK1144006T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK99966466T 1998-12-16 1999-12-16 Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil DK1144006T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11253298P 1998-12-16 1998-12-16
US21279398A 1998-12-16 1998-12-16
PCT/US1999/030345 WO2000035409A2 (en) 1998-12-16 1999-12-16 Hiv-i fusion inhibition compounds

Publications (1)

Publication Number Publication Date
DK1144006T3 true DK1144006T3 (da) 2007-11-26

Family

ID=26810060

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99966466T DK1144006T3 (da) 1998-12-16 1999-12-16 Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil

Country Status (13)

Country Link
EP (2) EP1144006B1 (da)
JP (1) JP2002538771A (da)
AT (1) ATE375802T1 (da)
AU (3) AU773175B2 (da)
CA (1) CA2355607A1 (da)
CY (1) CY1107858T1 (da)
DE (1) DE69937369T2 (da)
DK (1) DK1144006T3 (da)
ES (1) ES2296416T3 (da)
HK (1) HK1041207B (da)
MX (1) MXPA01006097A (da)
PT (1) PT1144006E (da)
WO (1) WO2000035409A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU723158B2 (en) 1995-06-07 2000-08-17 Progenics Pharmaceuticals, Inc. Fluorescence resonance energy transfer screening assay for the identification of HIV-1 envelope glycoprotein-medicated cell
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
AU2265701A (en) * 1999-12-16 2001-06-25 Tanox, Inc. Anti-hiv-1 conjugates for treatment of hiv disease
US7138119B2 (en) 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US20020146415A1 (en) * 2001-04-06 2002-10-10 Olson William C. Methods for inhibiting HIV-1 infection
US7060273B2 (en) 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
EP1456241B1 (en) * 2001-12-21 2005-03-16 Micromet AG Mono-and dual anti-cd4-rantes chemokine/cytokine constructs
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
NZ534947A (en) * 2002-02-22 2008-03-28 Progenics Pharm Inc Anti-CCR5 antibody that binds to CCR5 on the surface of a human cell.
TW200720289A (en) 2005-04-01 2007-06-01 Hoffmann La Roche Antibodies against CCR5 and uses thereof
JP2009525301A (ja) * 2006-01-30 2009-07-09 エフ．ホフマン−ラ ロシュ アーゲー Ｈｉｖを処置するための相乗的組成物
EP2054086A1 (en) 2006-08-17 2009-05-06 F. Hoffmann-Roche AG A conjugate of an antibody against ccr5 and an antifusogenic peptide
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
CN101516914A (zh) 2006-09-29 2009-08-26 霍夫曼-拉罗奇有限公司 针对ccr5的抗体及其应用
US20090143288A1 (en) 2007-03-13 2009-06-04 Roche Palo Alto Llc Peptide-complement conjugates
WO2013024022A1 (en) 2011-08-12 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treatment of pulmonary hypertension
US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045543A2 (en) * 1996-05-28 1997-12-04 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health Cc chemokine receptor 5, antibodies thereto, transgenic animals
EP0956044A4 (en) * 1996-06-14 2005-01-05 Progenics Pharm Inc USES OF A CHEMOKIN RECEPTOR TO INHIBIT HIV-1 INFECTION
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same

Also Published As

Publication number Publication date
CY1107858T1 (el) 2013-06-19
WO2000035409A2 (en) 2000-06-22
EP1144006B1 (en) 2007-10-17
AU773175B2 (en) 2004-05-20
EP1144006A4 (en) 2004-11-24
HK1041207B (en) 2007-12-28
ATE375802T1 (de) 2007-11-15
CA2355607A1 (en) 2000-06-22
EP1144006A2 (en) 2001-10-17
DE69937369T2 (de) 2008-07-24
ES2296416T3 (es) 2008-04-16
EP2088158A3 (en) 2010-01-20
EP2088158A2 (en) 2009-08-12
PT1144006E (pt) 2007-12-11
HK1041207A1 (en) 2002-07-05
AU2199600A (en) 2000-07-03
MXPA01006097A (es) 2002-04-15
JP2002538771A (ja) 2002-11-19
AU2004205164A1 (en) 2004-09-16
AU2004205165A1 (en) 2004-09-16
WO2000035409A3 (en) 2000-09-14
DE69937369D1 (de) 2007-11-29

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