DK1146866T3 - Metode til behandling af patienter med akne ved administration af cyclisk GMP PDE inhibitator - Google Patents
Metode til behandling af patienter med akne ved administration af cyclisk GMP PDE inhibitatorInfo
- Publication number
- DK1146866T3 DK1146866T3 DK00904556T DK00904556T DK1146866T3 DK 1146866 T3 DK1146866 T3 DK 1146866T3 DK 00904556 T DK00904556 T DK 00904556T DK 00904556 T DK00904556 T DK 00904556T DK 1146866 T3 DK1146866 T3 DK 1146866T3
- Authority
- DK
- Denmark
- Prior art keywords
- acne
- administration
- treating patients
- pde inhibitor
- cyclic gmp
- Prior art date
Links
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 title abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 2
- 206010000496 acne Diseases 0.000 title abstract 2
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 title 1
- ZOOGRGPOEVQQDX-UHFFFAOYSA-N cyclic GMP Natural products O1C2COP(O)(=O)OC2C(O)C1N1C=NC2=C1NC(N)=NC2=O ZOOGRGPOEVQQDX-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/239,840 US6025394A (en) | 1999-01-29 | 1999-01-29 | Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols |
| US09/378,660 US6177471B1 (en) | 1999-01-29 | 1999-08-20 | Method for treating patients with acne by administering a CGMP-specific PDE inhibitor |
| PCT/US2000/001840 WO2000044372A1 (en) | 1999-01-29 | 2000-01-25 | A method for treating patients with acne by administering a cyclic gmp pde inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1146866T3 true DK1146866T3 (da) | 2007-04-02 |
Family
ID=26932928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00904556T DK1146866T3 (da) | 1999-01-29 | 2000-01-25 | Metode til behandling af patienter med akne ved administration af cyclisk GMP PDE inhibitator |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1146866B1 (da) |
| JP (1) | JP2002535361A (da) |
| AT (1) | ATE346596T1 (da) |
| AU (1) | AU2629500A (da) |
| CA (1) | CA2360676C (da) |
| DE (1) | DE60032114T2 (da) |
| DK (1) | DK1146866T3 (da) |
| ES (1) | ES2277828T3 (da) |
| WO (1) | WO2000044372A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006054005A1 (de) * | 2006-11-16 | 2008-05-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Polymorphe von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester |
| CN111233706A (zh) * | 2020-01-19 | 2020-06-05 | 安徽峆一药业股份有限公司 | 一种舒林酸的绿色合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3532752A (en) * | 1965-12-30 | 1970-10-06 | Merck & Co Inc | 1-alkylidene-3-indenyl aliphatic amines |
| US5500230A (en) * | 1987-01-23 | 1996-03-19 | The General Hospital Corporation | Method for treatment of glaucoma with nitrogen containing guanylate cyclase activators |
| US5011843A (en) * | 1988-05-31 | 1991-04-30 | Iolab Corporation | Treatment of glaucoma using phosphodiesterase inhibitors |
| US5229516A (en) * | 1989-10-27 | 1993-07-20 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| US5401774A (en) * | 1991-03-08 | 1995-03-28 | University Of Arizona | Method for treating patients with precancerous lesions by administering substituted sulfonyl idenyl acetic and propionic acids and esters to patients with lesions sensitive to such compounds |
| AU650720B2 (en) * | 1991-03-08 | 1994-06-30 | Fgn, Inc. | Method for treating patients with precancerous lesions by administering substituted sulfonyl indenyl acetic and propionic acids and esters thereof |
-
2000
- 2000-01-25 CA CA002360676A patent/CA2360676C/en not_active Expired - Fee Related
- 2000-01-25 AU AU26295/00A patent/AU2629500A/en not_active Abandoned
- 2000-01-25 JP JP2000595675A patent/JP2002535361A/ja active Pending
- 2000-01-25 DE DE60032114T patent/DE60032114T2/de not_active Expired - Fee Related
- 2000-01-25 AT AT00904556T patent/ATE346596T1/de not_active IP Right Cessation
- 2000-01-25 DK DK00904556T patent/DK1146866T3/da active
- 2000-01-25 EP EP00904556A patent/EP1146866B1/en not_active Expired - Lifetime
- 2000-01-25 ES ES00904556T patent/ES2277828T3/es not_active Expired - Lifetime
- 2000-01-25 WO PCT/US2000/001840 patent/WO2000044372A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2277828T3 (es) | 2007-08-01 |
| CA2360676A1 (en) | 2000-08-03 |
| WO2000044372A1 (en) | 2000-08-03 |
| ATE346596T1 (de) | 2006-12-15 |
| EP1146866A1 (en) | 2001-10-24 |
| DE60032114T2 (de) | 2007-06-06 |
| EP1146866B1 (en) | 2006-11-29 |
| CA2360676C (en) | 2008-12-23 |
| AU2629500A (en) | 2000-08-18 |
| JP2002535361A (ja) | 2002-10-22 |
| DE60032114D1 (de) | 2007-01-11 |
| EP1146866A4 (en) | 2004-12-08 |
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