DK1148065T3 - Fusionsproteiner omfattende to oplöselige gp130-molekyler - Google Patents

Fusionsproteiner omfattende to oplöselige gp130-molekyler

Info

Publication number
DK1148065T3
DK1148065T3 DK00108691T DK00108691T DK1148065T3 DK 1148065 T3 DK1148065 T3 DK 1148065T3 DK 00108691 T DK00108691 T DK 00108691T DK 00108691 T DK00108691 T DK 00108691T DK 1148065 T3 DK1148065 T3 DK 1148065T3
Authority
DK
Denmark
Prior art keywords
soluble
sgp130
molecules
fusion proteins
responses
Prior art date
Application number
DK00108691T
Other languages
Danish (da)
English (en)
Inventor
Stefan Rose-John
Original Assignee
Conaris Res Inst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conaris Res Inst Ag filed Critical Conaris Res Inst Ag
Application granted granted Critical
Publication of DK1148065T3 publication Critical patent/DK1148065T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK00108691T 2000-04-21 2000-04-21 Fusionsproteiner omfattende to oplöselige gp130-molekyler DK1148065T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00108691A EP1148065B1 (de) 2000-04-21 2000-04-21 Fusionsproteine, die zwei lösliche gp130 Moleküle enthalten

Publications (1)

Publication Number Publication Date
DK1148065T3 true DK1148065T3 (da) 2008-04-28

Family

ID=8168532

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00108691T DK1148065T3 (da) 2000-04-21 2000-04-21 Fusionsproteiner omfattende to oplöselige gp130-molekyler

Country Status (8)

Country Link
EP (1) EP1148065B1 (de)
AT (1) ATE382636T1 (de)
CY (1) CY1107380T1 (de)
DE (1) DE60037648T2 (de)
DK (1) DK1148065T3 (de)
ES (1) ES2298106T3 (de)
PT (1) PT1148065E (de)
SI (1) SI1148065T1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100453877B1 (ko) * 2001-07-26 2004-10-20 메덱스젠 주식회사 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
DE10321317A1 (de) * 2003-05-13 2004-12-23 Christian-Albrechts-Universität Zu Kiel Verfahren zum Nachweis des funktionellen IL-6/ sIL-6-Rezeptor-Komplexes und Test-Kit zur Durchführung dieses Verfahrens
EP1491554A1 (de) * 2003-06-23 2004-12-29 CONARIS research institute AG PEGlierte lösliche gp130-Dimeren geignet als Medikament
EP1630232B1 (de) * 2004-08-27 2008-07-02 CONARIS research institute AG Optimierte Nukleotidsequenzen die für sgp130 kodieren
EP1801121A1 (de) * 2005-12-23 2007-06-27 CONARIS research institute AG Lösliche Varianten des Moleküls gp130 nützlich als Arzneimittel
ES2352561T3 (es) 2006-06-30 2011-02-21 Conaris Research Institute Ag Dímeros de sgp 130fc mejorados.
WO2009109584A1 (en) * 2008-03-07 2009-09-11 Ferring International Center S. A. ANTIBODY BINDING ONLY TO IL6-sIL6R COMPLEX
EP2643352B1 (de) * 2010-11-23 2018-05-02 Glaxo Group Limited Antigenbindende proteine zur bindung von oncostatin m (osm)
US20170165334A1 (en) * 2015-12-11 2017-06-15 Tianxin Wang Methods to Treat Diseases with Protein, Peptide, Antigen Modification and Hemopurification
RS65665B1 (sr) 2014-12-01 2024-07-31 Ferring Bv Selektivne kompozicije inhibitora il-6-trans-signalizacije
EP3226888B1 (de) * 2014-12-01 2021-04-21 Ferring B.V. Verabreichung eines selektiven il-6-transsignalisierenden inhibitors
WO2020178193A1 (en) 2019-03-01 2020-09-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Method of treatment of sarcoidosis
JP7781786B2 (ja) 2020-06-10 2025-12-08 フェリング・ベー・フェー アテローム性動脈硬化性心血管疾患を治療するための医薬化合物
WO2022139580A1 (en) 2020-12-22 2022-06-30 Ferring B.V. Blood gene expression biomarkers to predict response in patients with inflammatory bowel diseases
CN114681592A (zh) * 2020-12-31 2022-07-01 天境生物科技(杭州)有限公司 包含可溶性gp130二聚体的制剂和使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262522A (en) * 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M

Also Published As

Publication number Publication date
ATE382636T1 (de) 2008-01-15
SI1148065T1 (sl) 2008-06-30
ES2298106T3 (es) 2008-05-16
DE60037648T2 (de) 2010-06-17
PT1148065E (pt) 2008-04-03
EP1148065A1 (de) 2001-10-24
DE60037648D1 (de) 2008-02-14
CY1107380T1 (el) 2012-12-19
EP1148065B1 (de) 2008-01-02

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