DK1156058T3 - Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf - Google Patents

Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf

Info

Publication number: DK1156058T3
Authority: DK; Denmark
Prior art keywords: preparation; aminoethoxyimino; androstane; dione; analogs
Prior art date: 2000-05-17

Application number

DK01830306T

Other languages

Danish (da)

English (en)

Inventor

Mauro Gobbini

Giulio Carzana

Simona Sputore

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-17

Filing date

2001-05-14

Publication date

2007-06-18

2001-05-14 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2007-06-18 Application granted granted Critical

2007-06-18 Publication of DK1156058T3 publication Critical patent/DK1156058T3/da

Links

MPYLDWFDPHRTEG-IFVNMTGRSA-N (5s,8r,9s,10r,13s,14s)-3-(2-aminoethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione Chemical compound C1C(=NOCCN)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=O)[C@H]21 MPYLDWFDPHRTEG-IFVNMTGRSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK01830306T 2000-05-17 2001-05-14 Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf DK1156058T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2000RM000266A IT1317031B1 (it)	2000-05-17	2000-05-17	Procedimento migliorato per la preparazione di (e,z)3-(2-amminoetossimmino)-androstano-6, 17-dione e di suoi analoghi.

Publications (1)

Publication Number	Publication Date
DK1156058T3 true DK1156058T3 (da)	2007-06-18

Family

ID=11454735

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01830306T DK1156058T3 (da)	2000-05-17	2001-05-14	Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf

Country Status (9)

Country	Link
US (1)	US6384250B2 (de)
EP (1)	EP1156058B1 (de)
AT (1)	ATE355296T1 (de)
CY (1)	CY1107662T1 (de)
DE (1)	DE60126864T2 (de)
DK (1)	DK1156058T3 (de)
ES (1)	ES2282225T3 (de)
IT (1)	IT1317031B1 (de)
PT (1)	PT1156058E (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8168621B2 (en)	2005-09-30	2012-05-01	Endece, Llc	6-substituted estradiol derivatives and methods of use
US20080119447A1 (en) *	2005-09-30	2008-05-22	James Yarger	6-alkoxyalkyl estradiol derivatives and methods of use
US10174070B2 (en)	2005-09-30	2019-01-08	Endece Llc	6-substituted estradiol derivatives and methods of use
CN101594874B (zh)	2006-11-30	2017-02-08	安德斯有限责任公司	6‑烷氧基烷基雌二醇衍生物及用途
KR101585275B1 (ko) *	2007-10-12	2016-01-14	시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이.	심혈관 질환용 약제로서의 2 치환 및/또는 4 치환 안드로스탄 및 안드로스텐의 아미노옥심 유도체
WO2010149666A1 (en)	2009-06-22	2010-12-29	Medexis S.A.	Methods for treating neoplasia
CN103097396A (zh)	2010-09-14	2013-05-08	安德斯有限责任公司	作为ER-β 激动剂的6-取代的脱甲基-雌二醇衍生物
CN103315968B (zh) *	2013-06-26	2015-04-01	中国生命药物治疗有限公司	一种注射用粉针剂及其制备方法
CN103360457B (zh) *	2013-07-31	2015-10-07	中国生命药物治疗有限公司	一种雄甾烷二酮衍生物晶型及其制备方法
EP3934654B1 (de)	2019-03-05	2026-04-29	Windtree Therapeutics, Inc.	Istaroxim oder dessen metabolit pst-3093 zur verwendung als intravenöse formulierung zur behandlung von akutem herzversagen (ahv)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19633349A1 (de) *	1996-08-19	1998-02-26	Sigma Tau Ind Farmaceuti	Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten

2000
- 2000-05-17 IT IT2000RM000266A patent/IT1317031B1/it active
2001
- 2001-05-10 US US09/852,265 patent/US6384250B2/en not_active Expired - Lifetime
- 2001-05-14 DK DK01830306T patent/DK1156058T3/da active
- 2001-05-14 DE DE60126864T patent/DE60126864T2/de not_active Expired - Lifetime
- 2001-05-14 PT PT01830306T patent/PT1156058E/pt unknown
- 2001-05-14 ES ES01830306T patent/ES2282225T3/es not_active Expired - Lifetime
- 2001-05-14 AT AT01830306T patent/ATE355296T1/de active
- 2001-05-14 EP EP01830306A patent/EP1156058B1/de not_active Expired - Lifetime
2007
- 2007-05-09 CY CY20071100620T patent/CY1107662T1/el unknown

Also Published As

Publication number	Publication date
US20010056182A1 (en)	2001-12-27
EP1156058B1 (de)	2007-02-28
PT1156058E (pt)	2007-05-31
CY1107662T1 (el)	2013-04-18
US6384250B2 (en)	2002-05-07
ES2282225T3 (es)	2007-10-16
DE60126864D1 (de)	2007-04-12
DE60126864T2 (de)	2007-09-06
ITRM20000266A0 (it)	2000-05-17
EP1156058A3 (de)	2005-06-08
ATE355296T1 (de)	2006-03-15
IT1317031B1 (it)	2003-05-26
EP1156058A2 (de)	2001-11-21
ITRM20000266A1 (it)	2001-11-19

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