DK1161539T3 - Fremgangsmåde til at fremstille polyhydroxyalkanoater i rekombinante organismer - Google Patents
Fremgangsmåde til at fremstille polyhydroxyalkanoater i rekombinante organismerInfo
- Publication number
- DK1161539T3 DK1161539T3 DK00910451T DK00910451T DK1161539T3 DK 1161539 T3 DK1161539 T3 DK 1161539T3 DK 00910451 T DK00910451 T DK 00910451T DK 00910451 T DK00910451 T DK 00910451T DK 1161539 T3 DK1161539 T3 DK 1161539T3
- Authority
- DK
- Denmark
- Prior art keywords
- coas
- acyl
- action
- pathway
- produce
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 239000005014 poly(hydroxyalkanoate) Substances 0.000 title 1
- 229920000903 polyhydroxyalkanoate Polymers 0.000 title 1
- 230000037361 pathway Effects 0.000 abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000005870 Coenzyme A Ligases Human genes 0.000 abstract 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 1
- 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 abstract 1
- 102000001708 Protein Isoforms Human genes 0.000 abstract 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 102000005488 Thioesterase Human genes 0.000 abstract 1
- 102000002932 Thiolase Human genes 0.000 abstract 1
- 108060008225 Thiolase Proteins 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 235000021588 free fatty acids Nutrition 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 229920003023 plastic Polymers 0.000 abstract 1
- 239000004033 plastic Substances 0.000 abstract 1
- 108010010718 poly(3-hydroxyalkanoic acid) synthase Proteins 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000006491 synthase reaction Methods 0.000 abstract 1
- 108020002982 thioesterase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Biological Depolymerization Polymers (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12441799P | 1999-03-15 | 1999-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1161539T3 true DK1161539T3 (da) | 2005-11-28 |
Family
ID=22414762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00910451T DK1161539T3 (da) | 1999-03-15 | 2000-03-15 | Fremgangsmåde til at fremstille polyhydroxyalkanoater i rekombinante organismer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6492134B1 (da) |
| EP (1) | EP1161539B1 (da) |
| AT (1) | ATE300618T1 (da) |
| AU (1) | AU3266800A (da) |
| CA (1) | CA2365276C (da) |
| DE (1) | DE60021537T2 (da) |
| DK (1) | DK1161539T3 (da) |
| ES (1) | ES2243235T3 (da) |
| PT (1) | PT1161539E (da) |
| WO (1) | WO2000055328A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7176349B1 (en) | 1999-09-29 | 2007-02-13 | Pioneer Hi-Bred International, Inc. | Production of polyhydroxyalkanoate in plants |
| AU7741200A (en) * | 1999-09-29 | 2001-04-30 | E.I. Du Pont De Nemours And Company | Production of polyhydroxyalkanoate in plants |
| JP3768799B2 (ja) * | 2000-10-30 | 2006-04-19 | キヤノン株式会社 | 置換脂肪酸エステル化物を原料とするポリヒドロキシアルカノエートの製造方法 |
| AU3646402A (en) | 2000-11-17 | 2002-05-27 | Metabolix Inc | Production of medium chain length polyhydroxyalkanoates from fatty acid biosynthetic pathways |
| US6806401B2 (en) | 2000-12-27 | 2004-10-19 | Pioneer Hi-Bred International, Inc. | OAR polynucleotides, polypeptides and their use in PHA production in plants |
| JP3990880B2 (ja) * | 2001-07-10 | 2007-10-17 | キヤノン株式会社 | ポリヒドロキシアルカノエート被覆リポソームの製造方法 |
| KR101037354B1 (ko) * | 2007-09-07 | 2011-05-26 | 한국과학기술원 | 수크로스로부터 폴리락틱산 또는 폴리락틱산 공중합체를제조할 수 있는 재조합 미생물 및 이러한 미생물을이용하여 수크로스로부터 폴리락틱산 또는 락틱산공중합체를 제조하는 방법 |
| WO2009031762A2 (en) * | 2007-09-07 | 2009-03-12 | Lg Chem, Ltd. | Recombinant microorganism capable of producing polylactate or polylactate copolymer from sucrose and method for producing polylactate or polylactate copolymer from sucrose using the same |
| EP2565265A1 (en) | 2011-09-02 | 2013-03-06 | Philip Morris Products S.A. | Isopropylmalate synthase from Nicotiana tabacum and methods and uses thereof |
| US20140073022A1 (en) * | 2012-09-10 | 2014-03-13 | Wisconsin Alumni Research Foundation | Production of polyhydroxyalkanoates with a defined composition from an unrelated carbon source |
| EP2914251B1 (en) | 2012-11-05 | 2019-08-21 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Ketone bodies to protect tissues from damage by ionizing radiation |
| US20140283220A1 (en) * | 2013-03-15 | 2014-09-18 | Yi Li | Genetically Modified Plants that are Herbivore-Resistant |
| AU2014227823A1 (en) | 2013-03-15 | 2015-09-03 | Lisa HOLLISTER | Genetically modified plants that are insect-resistant and/or rot-resistant |
| WO2016040653A1 (en) * | 2014-09-12 | 2016-03-17 | Coffa Gianguido | Bioplastic production from non-sugar carbonaceous material |
| WO2024072953A1 (en) * | 2022-09-30 | 2024-04-04 | Kimberly-Clark Worldwide, Inc. | In vitro bioproduction of specific chain length poly(hydroxyalkanoate) monomers |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480794A (en) | 1987-06-29 | 1996-01-02 | Massachusetts Institute Of Technology And Metabolix, Inc. | Overproduction and purification of soluble PHA synthase |
| US5245023A (en) | 1987-06-29 | 1993-09-14 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| US5229279A (en) | 1987-06-29 | 1993-07-20 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| US5250430A (en) | 1987-06-29 | 1993-10-05 | Massachusetts Institute Of Technology | Polyhydroxyalkanoate polymerase |
| US5298421A (en) | 1990-04-26 | 1994-03-29 | Calgene, Inc. | Plant medium-chain-preferring acyl-ACP thioesterases and related methods |
| GB9108756D0 (en) | 1991-04-24 | 1991-06-12 | Ici Plc | Production of polyalkanoate in plants |
| US5610041A (en) * | 1991-07-19 | 1997-03-11 | Board Of Trustees Operating Michigan State University | Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants |
| BR9206297A (pt) | 1991-07-19 | 1995-10-17 | Univ Michigan State | Plantas transgênicas produzindo poli-hidroxialcanoatos |
| GB9502456D0 (en) | 1995-02-08 | 1995-03-29 | Univ Warwick | Control of genes in transgenic plants |
| US5959179A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Method for transforming soybeans |
| US5958745A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
| US5750848A (en) | 1996-08-13 | 1998-05-12 | Monsanto Company | DNA sequence useful for the production of polyhydroxyalkanoates |
| WO1998036078A1 (en) | 1997-02-13 | 1998-08-20 | James Madison University | Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units |
| US6143561A (en) * | 1997-06-30 | 2000-11-07 | The Curators Of The University Of Missouri | DNA encoding plastid pyruvate dehydrogenase and branched chain oxoacid dehydrogenase components |
| US6103956A (en) * | 1998-03-31 | 2000-08-15 | Regents Of The University Of Minnesota | Polyhydroxyalkanoate synthesis in plants |
| US6265202B1 (en) * | 1998-06-26 | 2001-07-24 | Regents Of The University Of Minnesota | DNA encoding methymycin and pikromycin |
-
2000
- 2000-03-15 ES ES00910451T patent/ES2243235T3/es not_active Expired - Lifetime
- 2000-03-15 DK DK00910451T patent/DK1161539T3/da active
- 2000-03-15 EP EP00910451A patent/EP1161539B1/en not_active Expired - Lifetime
- 2000-03-15 WO PCT/CA2000/000275 patent/WO2000055328A1/en not_active Ceased
- 2000-03-15 CA CA002365276A patent/CA2365276C/en not_active Expired - Fee Related
- 2000-03-15 US US09/526,098 patent/US6492134B1/en not_active Expired - Fee Related
- 2000-03-15 DE DE60021537T patent/DE60021537T2/de not_active Expired - Lifetime
- 2000-03-15 AT AT00910451T patent/ATE300618T1/de active
- 2000-03-15 AU AU32668/00A patent/AU3266800A/en not_active Abandoned
- 2000-03-15 PT PT00910451T patent/PT1161539E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000055328A1 (en) | 2000-09-21 |
| ES2243235T3 (es) | 2005-12-01 |
| EP1161539A1 (en) | 2001-12-12 |
| CA2365276C (en) | 2009-08-25 |
| EP1161539B1 (en) | 2005-07-27 |
| PT1161539E (pt) | 2005-09-30 |
| DE60021537T2 (de) | 2006-06-01 |
| AU3266800A (en) | 2000-10-04 |
| DE60021537D1 (de) | 2005-09-01 |
| ATE300618T1 (de) | 2005-08-15 |
| US6492134B1 (en) | 2002-12-10 |
| CA2365276A1 (en) | 2000-09-21 |
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