DK1204659T3 - Serotonerge benzofuraner - Google Patents

Serotonerge benzofuraner

Info

Publication number
DK1204659T3
DK1204659T3 DK00955245T DK00955245T DK1204659T3 DK 1204659 T3 DK1204659 T3 DK 1204659T3 DK 00955245 T DK00955245 T DK 00955245T DK 00955245 T DK00955245 T DK 00955245T DK 1204659 T3 DK1204659 T3 DK 1204659T3
Authority
DK
Denmark
Prior art keywords
benzofurans
serotonergic
formula
provides
present
Prior art date
Application number
DK00955245T
Other languages
English (en)
Inventor
Karin Briner
Joseph Paul Burkhart
Timothy Paul Burkholder
Matthew Joseph Fisher
William Harlan Gritton
Cynthia Darshini Jesudason
Shawn Christopher Miller
Jeffrey Thomas Mullaney
Matthew Robert Reinhard
Roger Ryan Rothhaar
Leonard Larry Winneroski Jr
Yanping Xu
Yao-Chang Xu
Brian Eugene Cunningham
Freddie Craig Stevens
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1204659T3 publication Critical patent/DK1204659T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyethers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Dental Preparations (AREA)
  • Furan Compounds (AREA)
DK00955245T 1999-07-29 2000-07-21 Serotonerge benzofuraner DK1204659T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14618199P 1999-07-29 1999-07-29
US17260199P 1999-12-20 1999-12-20
PCT/US2000/019544 WO2001009122A2 (en) 1999-07-29 2000-07-21 Serotonergic benzofurans

Publications (1)

Publication Number Publication Date
DK1204659T3 true DK1204659T3 (da) 2004-04-05

Family

ID=26843646

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00955245T DK1204659T3 (da) 1999-07-29 2000-07-21 Serotonerge benzofuraner

Country Status (13)

Country Link
EP (1) EP1204659B1 (da)
JP (1) JP2003506369A (da)
CN (1) CN1407982A (da)
AT (1) ATE255105T1 (da)
AU (1) AU768339B2 (da)
BR (1) BR0012751A (da)
CA (1) CA2380608A1 (da)
DE (1) DE60006825T2 (da)
DK (1) DK1204659T3 (da)
ES (1) ES2209951T3 (da)
MX (1) MXPA02000914A (da)
PT (1) PT1204659E (da)
WO (1) WO2001009122A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
JP4204315B2 (ja) 2000-11-20 2009-01-07 ビオヴィトルム・アクチボラゲット（プブリクト） セロトニン５−ｈｔ２レセプターのアンタゴニストとしてのピペラジニルピラジン化合物
BR0311970A (pt) 2002-06-19 2005-03-29 Biovitrum Ab Novos compostos, seu uso e preparação
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
JP5528699B2 (ja) 2006-05-16 2014-06-25 武田薬品工業株式会社 縮合複素環化合物およびその用途
JP5520051B2 (ja) 2007-11-15 2014-06-11 武田薬品工業株式会社 縮合ピリジン誘導体およびその用途
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
CN103601669B (zh) * 2013-05-20 2016-08-03 甘肃科瑞生物科技有限公司 一种1-叔丁氧羰基-2-甲基-4-哌啶酮的合成方法
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
KR102037494B1 (ko) 2017-12-11 2019-10-28 씨제이헬스케어 주식회사 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법
WO2019131902A1 (ja) 2017-12-27 2019-07-04 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬
CN110317129A (zh) * 2019-05-30 2019-10-11 杭州迈世腾药物科技有限公司 2-溴-5-甲氧基苯酚的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (de) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
ATE81975T1 (de) * 1984-12-21 1992-11-15 Duphar Int Res Arzneimittel mit psychotroper wirkung.
EP0398413A1 (en) * 1989-05-16 1990-11-22 Duphar International Research B.V "3,4-dehydropiperidine derivatives having psychotropic activity
JP2883995B2 (ja) * 1990-03-14 1999-04-19 第一製薬株式会社 ピペリジン誘導体及びその製造中間体
AR019178A1 (es) * 1998-06-30 2001-12-26 Lilly Co Eli Compuestos de 7-(benzo(b)tiofeno, furan e indolpiridil o tetrahidropiridilo), efectivos sobre sistemas relacionados con la serotonina, composicionesfarmaceuticas formuladas con dichos compuestos; compuestos intermediarios utiles para preparar dichos compuestos de tiofeno, furan e indolpiridilo otetr
EP1100501A4 (en) * 1998-06-30 2002-12-04 Lilly Co Eli PYRROLIDINE AND PYRROLIDINE DERIVATIVES INFLUENTING THE SYSTEMS ASSOCIATED WITH SEROTONIN
AU4727799A (en) * 1998-06-30 2000-01-17 Eli Lilly And Company Azepine derivatives having effects on serotonin related systems

Also Published As

Publication number Publication date
DE60006825T2 (de) 2004-08-12
WO2001009122A2 (en) 2001-02-08
BR0012751A (pt) 2002-06-04
MXPA02000914A (es) 2002-07-30
DE60006825D1 (de) 2004-01-08
CN1407982A (zh) 2003-04-02
WO2001009122A3 (en) 2001-06-28
CA2380608A1 (en) 2001-02-08
PT1204659E (pt) 2004-04-30
EP1204659B1 (en) 2003-11-26
AU6747400A (en) 2001-02-19
AU768339B2 (en) 2003-12-11
ES2209951T3 (es) 2004-07-01
EP1204659A2 (en) 2002-05-15
JP2003506369A (ja) 2003-02-18
ATE255105T1 (de) 2003-12-15

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