DK1240186T3 - Forbedringer i eller relateret til immunrespons mod HIV - Google Patents
Forbedringer i eller relateret til immunrespons mod HIVInfo
- Publication number
- DK1240186T3 DK1240186T3 DK00985690.7T DK00985690T DK1240186T3 DK 1240186 T3 DK1240186 T3 DK 1240186T3 DK 00985690 T DK00985690 T DK 00985690T DK 1240186 T3 DK1240186 T3 DK 1240186T3
- Authority
- DK
- Denmark
- Prior art keywords
- hiv
- immune response
- immunogen
- synthetic polypeptide
- protein
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title abstract 2
- 101710177291 Gag polyprotein Proteins 0.000 abstract 2
- 101710125418 Major capsid protein Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108091035707 Consensus sequence Proteins 0.000 abstract 1
- 108010048209 Human Immunodeficiency Virus Proteins Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930294.5A GB9930294D0 (en) | 1999-12-23 | 1999-12-23 | Improvements in or relating to immune responses to HIV |
| GB0025234A GB0025234D0 (en) | 2000-10-14 | 2000-10-14 | Improvements in or relating to immune responses to HIV |
| PCT/GB2000/004984 WO2001047955A2 (en) | 1999-12-23 | 2000-12-22 | Improvements in or relating to immune responses to hiv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1240186T3 true DK1240186T3 (da) | 2010-05-31 |
Family
ID=26245157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00985690.7T DK1240186T3 (da) | 1999-12-23 | 2000-12-22 | Forbedringer i eller relateret til immunrespons mod HIV |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7993651B2 (da) |
| EP (1) | EP1240186B1 (da) |
| JP (1) | JP4805511B2 (da) |
| CN (1) | CN1213068C (da) |
| AT (1) | ATE457996T1 (da) |
| AU (1) | AU784679B2 (da) |
| BR (1) | BR0016510A (da) |
| CA (1) | CA2392877C (da) |
| CY (1) | CY1110917T1 (da) |
| DE (1) | DE60043856D1 (da) |
| DK (1) | DK1240186T3 (da) |
| ES (1) | ES2341429T3 (da) |
| MX (1) | MXPA02006379A (da) |
| PT (1) | PT1240186E (da) |
| WO (1) | WO2001047955A2 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1980617A1 (en) | 1998-12-31 | 2008-10-15 | Novartis Vaccines and Diagnostics, Inc. | Improved expression of HIV polypeptides and production of virus-like particles |
| WO2000039304A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| WO2001092470A2 (en) | 2000-03-02 | 2001-12-06 | Emory University | Dna expression vectors and methods of use |
| US8623379B2 (en) | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| PT1372710E (pt) | 2001-03-08 | 2009-12-21 | Us Gov Health & Human Serv | Vam modificado que expressa os genes gag e pol do envelope de vih |
| CA2452015C (en) | 2001-07-05 | 2012-07-03 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| MXPA04002631A (es) * | 2001-09-20 | 2004-07-08 | Glaxo Group Ltd | Vacunas de adn optimizadas por codon gag-vih. |
| GB0225788D0 (en) | 2002-11-05 | 2002-12-11 | Glaxo Group Ltd | Vaccine |
| US7425611B2 (en) * | 2003-03-28 | 2008-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Immunogenic HIV-1 multi-clade, multivalent constructs and methods of their use |
| AU2004279362B2 (en) | 2003-09-15 | 2011-03-17 | Genvec, Inc. | HIV vaccines based on ENV of multiple clades of HIV |
| WO2005030964A1 (en) * | 2003-09-24 | 2005-04-07 | Oxxon Therapeutics Limited | Hiv pharmaccines |
| WO2005047483A2 (en) | 2003-11-12 | 2005-05-26 | Medical Research Council | Renta: an hiv immunogen and uses thereof |
| TW200613554A (en) * | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| ATE527281T1 (de) | 2004-07-16 | 2011-10-15 | Us Gov Health & Human Serv | Impfstoffe gegen aids umfassend cmv/r nucleinsäurekonstrukte |
| GB0417494D0 (en) * | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| CA2597511A1 (en) * | 2005-02-24 | 2006-11-23 | Medical Research Council | Hivcon: an hiv immunogen and uses thereof |
| DK2029168T3 (da) | 2006-06-02 | 2013-01-14 | Int Aids Vaccine Initiative | HIV-1 Clade A konsensussekvenser, antigener og transgener. |
| WO2010096561A1 (en) * | 2009-02-18 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthetic hiv/siv gag proteins and uses thereof |
| KR20120093941A (ko) * | 2009-10-08 | 2012-08-23 | 버베리안 노딕 에이/에스 | 인간에서 hiv에 대한 광범위한 t-세포 반응의 생성 |
| WO2011119920A2 (en) | 2010-03-25 | 2011-09-29 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| CA2817418A1 (en) * | 2010-11-10 | 2012-05-18 | Laboratorios Del Dr. Esteve, S.A. | Highly immunogenic hiv p24 sequences |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| EP2620446A1 (en) | 2012-01-27 | 2013-07-31 | Laboratorios Del Dr. Esteve, S.A. | Immunogens for HIV vaccination |
| US9347065B2 (en) | 2012-03-29 | 2016-05-24 | International Aids Vaccine Initiative | Methods to improve vector expression and genetic stability |
| ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
| ES2807173T3 (es) | 2012-09-10 | 2021-02-22 | Int Aids Vaccine Initiative | Inmunógenos de anticuerpos ampliamente neutralizantes del VIH-1, métodos de generación y usos de los mismos |
| EP2745845A1 (en) | 2012-12-19 | 2014-06-25 | Centre Hospitalier Universitaire de Bordeaux | A method for preventing or treating an HIV infection |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| EP3116895A4 (en) * | 2014-03-12 | 2017-08-16 | Temple University Of The Commonwealth System Of Higher Education | Dr6 receptor mediates the leukemia differentiation activity of angiocidin: a potent anti-tumor peptide |
| US10093720B2 (en) | 2014-06-11 | 2018-10-09 | International Aids Vaccine Initiative | Broadly neutralizing antibody and uses thereof |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9925258B2 (en) | 2015-10-02 | 2018-03-27 | International Aids Vaccine Initiative | Replication-competent VSV-HIV Env vaccines |
| EP3426353A4 (en) | 2016-03-09 | 2020-05-06 | The University of Massachusetts | USE OF MODIFIED HIV-1 TO GENERATE FULLY HUMAN ANTIBODIES |
| KR20220011685A (ko) | 2019-05-22 | 2022-01-28 | 길리애드 사이언시즈, 인코포레이티드 | Tlr7 조절 화합물과 hiv 백신의 조합 |
| AU2020298552A1 (en) * | 2019-07-02 | 2022-03-03 | Seattle Project Corp. | HIV antigens and MHC complexes |
| EP4058058A1 (en) | 2019-11-14 | 2022-09-21 | Aelix Therapeutics S.L. | Dosage regimens for vaccines |
| WO2021185851A1 (en) | 2020-03-17 | 2021-09-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine compositions for hiv prevention and treatment |
| CA3173793A1 (en) | 2020-04-03 | 2021-10-07 | Andrew Ferguson | Infectious disease antigens and vaccines |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2869063B2 (ja) | 1985-04-08 | 1999-03-10 | ジエネテイツク システムズ コ−ポレイシヨン | LAVに対する抗体と免疫的に反応性であるgagによりコードされたペプチドの発現及び使用 |
| US4784941A (en) | 1985-04-08 | 1988-11-15 | Genetic Systems Corporation | Expression and diagnostic use of pENV-3 encoded peptides which are immunologically reactive with antibodies to LAV |
| US4629783A (en) | 1985-04-29 | 1986-12-16 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| US5175098A (en) | 1985-08-07 | 1992-12-29 | Genetic Systems Corporation | Expression and diagnostic use of gag encoded peptides which are immunologically reactive with antibodies to HIV |
| US5175097A (en) | 1985-08-07 | 1992-12-29 | Genetic Systems Corporation | Expression and diagnostic use of GAG-1 encoded peptides which are immunologically reactive with antibodies to HIV |
| US5134227A (en) | 1986-02-27 | 1992-07-28 | Centocor, Inc. | DNA encoding immunoreactive, chimeric HTLV-III GAG proteins |
| US4808536A (en) | 1986-02-27 | 1989-02-28 | Centocor, Inc. | Immunochemical method for detection of antibody against HTLV-III core protein based upon recombinant HTLV-III gag gene encoded protein |
| US4822606A (en) | 1986-04-07 | 1989-04-18 | Duke University | Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences |
| US5993819A (en) | 1987-09-08 | 1999-11-30 | Duke University | Synthetic vaccine for protection against human immunodeficiency virus infection |
| GB2220939B (en) | 1988-06-10 | 1992-02-26 | Medical Res Council | Peptide fragments of hiv and their use in vaccines and diagnosis |
| US5817318A (en) | 1989-05-03 | 1998-10-06 | Connaught Laboratories Limited | Synthetic peptides for an HIV-1 vaccine |
| US5210181A (en) | 1989-05-15 | 1993-05-11 | Akzo N.V. | T-lymphotropic retrovirus peptide |
| GB8918200D0 (en) | 1989-08-09 | 1989-09-20 | Medical Res Council | The peptide fragments of hiv |
| CA2025634A1 (en) | 1989-09-19 | 1991-03-20 | Thomas Fuerst | Peptides including ctl epitopes of hiv proteins and use thereof |
| DE3934366A1 (de) | 1989-10-14 | 1991-04-18 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum |
| US5480967A (en) | 1990-01-05 | 1996-01-02 | United Biomedical, Inc. | HIV-1 core protein fragments |
| DE69231705T2 (de) * | 1992-06-04 | 2001-10-18 | The Research Foundation For Microbial Diseases Of Osaka University, Suita | Gag-Env Fusion-Antigen aus HIV |
| JP3277045B2 (ja) | 1992-10-06 | 2002-04-22 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | Hiv−グループのレトロウイルスおよびその使用 |
| JPH08511007A (ja) | 1993-06-09 | 1996-11-19 | コノート ラボラトリーズ リミテッド | タンデム合成hiv−1ペプチド |
| US6225045B1 (en) | 1996-05-13 | 2001-05-01 | Ribotargets, Ltd. | Assays for screening for inhibitors of HIV |
| AU731367B2 (en) | 1996-08-09 | 2001-03-29 | Viral Technologies, Inc. | HIV p-17 peptide fragment, compositions containing and methods for producing and using same |
| US6093400A (en) | 1996-08-09 | 2000-07-25 | Cel Sci Corporation | Modified HGP-30 peptides, conjugates, compositions and methods of use |
| US6271354B1 (en) | 1997-04-03 | 2001-08-07 | Thomas Jefferson University | Chimeric viral proteins |
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| AU6139699A (en) * | 1998-09-11 | 2000-04-03 | Children's Medical Center Corporation | Packaging cell lines for hiv-derived retroviral vector particles |
| HK1044040A1 (zh) * | 1998-11-16 | 2002-10-04 | 德克萨斯州立大学董事会 | Hiv-特异的t-细胞诱导 |
| WO2000039304A2 (en) * | 1998-12-31 | 2000-07-06 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| EP1088889A1 (en) | 1999-10-01 | 2001-04-04 | University Of Cambridge | Recombinant double hybrid filamentous bacteriophage |
-
2000
- 2000-12-22 WO PCT/GB2000/004984 patent/WO2001047955A2/en not_active Ceased
- 2000-12-22 DE DE60043856T patent/DE60043856D1/de not_active Expired - Lifetime
- 2000-12-22 CA CA2392877A patent/CA2392877C/en not_active Expired - Fee Related
- 2000-12-22 EP EP00985690A patent/EP1240186B1/en not_active Expired - Lifetime
- 2000-12-22 ES ES00985690T patent/ES2341429T3/es not_active Expired - Lifetime
- 2000-12-22 AT AT00985690T patent/ATE457996T1/de active
- 2000-12-22 AU AU22089/01A patent/AU784679B2/en not_active Ceased
- 2000-12-22 CN CNB008176779A patent/CN1213068C/zh not_active Expired - Fee Related
- 2000-12-22 DK DK00985690.7T patent/DK1240186T3/da active
- 2000-12-22 BR BR0016510-7A patent/BR0016510A/pt not_active IP Right Cessation
- 2000-12-22 MX MXPA02006379A patent/MXPA02006379A/es active IP Right Grant
- 2000-12-22 US US10/168,843 patent/US7993651B2/en not_active Expired - Fee Related
- 2000-12-22 PT PT00985690T patent/PT1240186E/pt unknown
- 2000-12-22 JP JP2001549425A patent/JP4805511B2/ja not_active Expired - Fee Related
-
2010
- 2010-05-14 CY CY20101100421T patent/CY1110917T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4805511B2 (ja) | 2011-11-02 |
| US20030108562A1 (en) | 2003-06-12 |
| MXPA02006379A (es) | 2004-06-21 |
| US7993651B2 (en) | 2011-08-09 |
| CN1434831A (zh) | 2003-08-06 |
| CY1110917T1 (el) | 2015-06-10 |
| DE60043856D1 (de) | 2010-04-01 |
| EP1240186A2 (en) | 2002-09-18 |
| BR0016510A (pt) | 2002-08-27 |
| PT1240186E (pt) | 2010-03-25 |
| WO2001047955A2 (en) | 2001-07-05 |
| JP2003518931A (ja) | 2003-06-17 |
| AU2208901A (en) | 2001-07-09 |
| HK1058048A1 (en) | 2004-04-30 |
| ATE457996T1 (de) | 2010-03-15 |
| CA2392877C (en) | 2011-11-15 |
| WO2001047955A3 (en) | 2002-05-10 |
| ES2341429T3 (es) | 2010-06-21 |
| EP1240186B1 (en) | 2010-02-17 |
| CN1213068C (zh) | 2005-08-03 |
| CA2392877A1 (en) | 2001-07-05 |
| AU784679B2 (en) | 2006-05-25 |
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