DK1255745T3 - Syntese af vandoplöseligt 9-dihydro-paclitaxel afledninger fra 9-dihydro-13-acetylbaccatin III - Google Patents
Syntese af vandoplöseligt 9-dihydro-paclitaxel afledninger fra 9-dihydro-13-acetylbaccatin IIIInfo
- Publication number
- DK1255745T3 DK1255745T3 DK01921710T DK01921710T DK1255745T3 DK 1255745 T3 DK1255745 T3 DK 1255745T3 DK 01921710 T DK01921710 T DK 01921710T DK 01921710 T DK01921710 T DK 01921710T DK 1255745 T3 DK1255745 T3 DK 1255745T3
- Authority
- DK
- Denmark
- Prior art keywords
- dihydro
- synthesis
- soluble
- water
- paclitaxel derivatives
- Prior art date
Links
- WPPPFZJNKLMYBW-FAEUQDRCSA-N 13-acetyl-9-dihydrobaccatin iii Chemical compound O([C@@H]1[C@]2(O)C[C@@H](C(=C([C@@H](OC(C)=O)[C@H](O)[C@]3(C)[C@@H](O)C[C@H]4OC[C@]4([C@H]31)OC(C)=O)C2(C)C)C)OC(=O)C)C(=O)C1=CC=CC=C1 WPPPFZJNKLMYBW-FAEUQDRCSA-N 0.000 title 1
- FFCWRLFQIKDRNO-UHFFFAOYSA-N 9-dihydro-13-acetyl baccatin III Natural products CC(=O)OC1C2C(O)CC(OC(=O)C)C3(CO3)C2C(OC(=O)C)C4(O)CC(OC(=O)C)C(=C(C1OC(=O)C)C4(C)C)C FFCWRLFQIKDRNO-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/494,629 US6175023B1 (en) | 2000-01-31 | 2000-01-31 | Synthesis of water soluble 9-dihydro-paclitaxel derivatives from 9-dihydro-13-acetylbaccatin III |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1255745T3 true DK1255745T3 (da) | 2004-05-17 |
Family
ID=23965272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01921710T DK1255745T3 (da) | 2000-01-31 | 2001-01-31 | Syntese af vandoplöseligt 9-dihydro-paclitaxel afledninger fra 9-dihydro-13-acetylbaccatin III |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6175023B1 (da) |
| EP (1) | EP1255745B1 (da) |
| JP (1) | JP2003531826A (da) |
| KR (1) | KR20030009347A (da) |
| AT (1) | ATE257831T1 (da) |
| AU (1) | AU784830B2 (da) |
| CA (1) | CA2398655A1 (da) |
| DE (1) | DE60101784T2 (da) |
| DK (1) | DK1255745T3 (da) |
| ES (1) | ES2214410T3 (da) |
| PT (1) | PT1255745E (da) |
| TR (1) | TR200400293T4 (da) |
| WO (1) | WO2001055126A2 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2276708T3 (es) * | 1999-11-24 | 2007-07-01 | Immunogen, Inc. | Agentes citotoxicos que comprenden taxanos y su uso terapeutico. |
| US7239669B2 (en) * | 2002-04-30 | 2007-07-03 | Fulcrum Microsystems, Inc. | Asynchronous system-on-a-chip interconnect |
| US7390898B2 (en) * | 2002-08-02 | 2008-06-24 | Immunogen Inc. | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
| KR20050032110A (ko) | 2002-08-02 | 2005-04-06 | 이뮤노젠 아이엔씨 | 신규의 효능을 갖는 탁산을 포함하는 세포독성제 및 그치료용도 |
| AU2003273671A1 (en) * | 2002-10-09 | 2004-05-04 | Phytogen Life Sciences, Inc. | Novel taxanes and methods related to use and preparation thereof |
| US7202370B2 (en) * | 2003-10-27 | 2007-04-10 | Conor Medsystems, Inc. | Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III |
| US7771563B2 (en) * | 2004-11-18 | 2010-08-10 | Sumitomo Precision Products Co., Ltd. | Systems and methods for achieving isothermal batch processing of substrates used for the production of micro-electro-mechanical-systems |
| CA2599888C (en) * | 2005-03-31 | 2010-06-15 | Bioxel Pharma Inc. | Preparation of taxanes from 9-dihydro-13-acetylbaccatin iii |
| US7847111B2 (en) * | 2006-06-19 | 2010-12-07 | Canada Inc. | Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69325454T2 (de) | 1992-04-17 | 2000-01-20 | Abbott Laboratories, Abbott Park | Taxol-derivate |
| CA2204197A1 (en) * | 1997-05-01 | 1998-11-01 | Jian Liu | Process for converting 9-dihydro-13-acetylbaccatin iii into taxol and derivatives thereof |
-
2000
- 2000-01-31 US US09/494,629 patent/US6175023B1/en not_active Expired - Fee Related
-
2001
- 2001-01-31 JP JP2001560985A patent/JP2003531826A/ja active Pending
- 2001-01-31 PT PT01921710T patent/PT1255745E/pt unknown
- 2001-01-31 AT AT01921710T patent/ATE257831T1/de not_active IP Right Cessation
- 2001-01-31 TR TR2004/00293T patent/TR200400293T4/xx unknown
- 2001-01-31 CA CA002398655A patent/CA2398655A1/en not_active Abandoned
- 2001-01-31 WO PCT/IB2001/000646 patent/WO2001055126A2/en not_active Ceased
- 2001-01-31 AU AU48678/01A patent/AU784830B2/en not_active Ceased
- 2001-01-31 KR KR1020027009869A patent/KR20030009347A/ko not_active Ceased
- 2001-01-31 EP EP01921710A patent/EP1255745B1/en not_active Expired - Lifetime
- 2001-01-31 DK DK01921710T patent/DK1255745T3/da active
- 2001-01-31 DE DE60101784T patent/DE60101784T2/de not_active Expired - Fee Related
- 2001-01-31 ES ES01921710T patent/ES2214410T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1255745A2 (en) | 2002-11-13 |
| CA2398655A1 (en) | 2001-08-02 |
| PT1255745E (pt) | 2004-04-30 |
| AU784830B2 (en) | 2006-06-29 |
| JP2003531826A (ja) | 2003-10-28 |
| EP1255745B1 (en) | 2004-01-14 |
| TR200400293T4 (tr) | 2004-04-21 |
| ATE257831T1 (de) | 2004-01-15 |
| DE60101784T2 (de) | 2004-11-11 |
| ES2214410T3 (es) | 2004-09-16 |
| AU4867801A (en) | 2001-08-07 |
| WO2001055126A3 (en) | 2002-01-10 |
| US6175023B1 (en) | 2001-01-16 |
| WO2001055126A2 (en) | 2001-08-02 |
| DE60101784D1 (de) | 2004-02-19 |
| KR20030009347A (ko) | 2003-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60107449D1 (de) | Substituierte aminopropoxyarylderivate als lxr agonisten | |
| CY1113657T1 (el) | Νεα παραγωγα βενζοφαινονης ή αλατα αυτων | |
| UY28290A1 (es) | Compuestos farmacéuticos novedosos | |
| DOP2001000151A (es) | Derivados de imidazopirimidina y derivados de triazolopimidina. | |
| SE0000540D0 (sv) | New compounds | |
| EA200300429A1 (ru) | Способ получения порошковых композиций | |
| DK1385515T3 (da) | Spiropyrazole forbindelser | |
| CY1106247T1 (el) | Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες | |
| DE602004009200D1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| EA200600485A1 (ru) | Способ получения производных 2-оксо-1-пирролидина | |
| ATE503746T1 (de) | Neue imidazolidinderivate | |
| HRP20080057T3 (en) | 9,10-alpha,alpha-oh-taxane analogs and methods for production thereof | |
| MY138826A (en) | 2,7-substituted indoles | |
| EA200301317A1 (ru) | Производные аминохинолина и его применение в качестве лигандов аденозина a3 | |
| UY27250A1 (es) | Fenil-heterociclil-cteres | |
| BR0209901A (pt) | Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina | |
| CY1107101T1 (el) | Μεθοδος συνθεσης παραγωγων της 1,3-διϋδρο-2h-3-βενζαζεπιν-2-ονης και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης με φαρμακευτικως αποδεκτο οξυ | |
| DE60101784D1 (de) | Synthese von wasserlöslischem 9-dihydroplacitaxel derivate aus 9-dihydro-13-acetylbacchatin iii | |
| WO2005000804A3 (en) | Substituted indoles and a process for preparing substituted indoles | |
| TR200402546T4 (tr) | Taksan türevleri hazırlamak için işlem. | |
| JO2251B1 (en) | A multi-step method for preparing derivatives of 5.4-dichromic amino acid | |
| DK1105392T3 (da) | Fremgangsmåde til fremstilling af mellemprodukter for imidazodiazepin | |
| DK1339703T3 (da) | Fremgangsmåde til fremstilling af paclitaxel | |
| DK1280752T3 (da) | Fremgangsmåde til fremstilling af 2-alkyl-3-chlorphenoler | |
| DK1265908T3 (da) | Fremgangsmåde til fremstilling af derivater af 9-deoxo-8a-aza-(8a-alkyl)-8a-homoerythromycin A ud fra 9-deoxo-9(Z)-hydroxyiminoerythromycin A |