DK1263968T4 - Beta 1,2-xylosyltransferasegen fra arabidopsis - Google Patents

Beta 1,2-xylosyltransferasegen fra arabidopsis

Info

Publication number
DK1263968T4
DK1263968T4 DK01919367.1T DK01919367T DK1263968T4 DK 1263968 T4 DK1263968 T4 DK 1263968T4 DK 01919367 T DK01919367 T DK 01919367T DK 1263968 T4 DK1263968 T4 DK 1263968T4
Authority
DK
Denmark
Prior art keywords
arabidopsis
beta
less
glycoprotein
human protein
Prior art date
Application number
DK01919367.1T
Other languages
English (en)
Other versions
DK1263968T3 (da
Inventor
Richard Strasser
Jan Mucha
Lukas Mach
Friedrich Altmann
Iain B Wilson
Josef Glössl
Herta Steinkellner
Original Assignee
Josef Glössl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3672559&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1263968(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Josef Glössl filed Critical Josef Glössl
Publication of DK1263968T3 publication Critical patent/DK1263968T3/da
Application granted granted Critical
Publication of DK1263968T4 publication Critical patent/DK1263968T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024—Alpha-mannosidase (3.2.1.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DK01919367.1T 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis DK1263968T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
PCT/EP2001/002352 WO2001064901A1 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis

Publications (2)

Publication Number Publication Date
DK1263968T3 DK1263968T3 (da) 2006-05-01
DK1263968T4 true DK1263968T4 (da) 2014-11-03

Family

ID=3672559

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05108014.1T DK1621633T3 (da) 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase
DK01919367.1T DK1263968T4 (da) 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK05108014.1T DK1621633T3 (da) 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase

Country Status (12)

Country Link
US (3) US7205137B2 (da)
EP (2) EP1263968B2 (da)
JP (2) JP5279976B2 (da)
KR (5) KR100859919B1 (da)
AT (2) AT409381B (da)
AU (1) AU781010B2 (da)
CA (1) CA2402015C (da)
DE (1) DE60115863T3 (da)
DK (2) DK1621633T3 (da)
ES (2) ES2460672T3 (da)
PT (1) PT1621633E (da)
WO (1) WO2001064901A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ512185A (en) 1998-12-09 2004-02-27 Dow Chemical Co A method for manufacturing glycoproteins having human- type glycosylation in plant cells
AU1738401A (en) 1999-10-26 2001-05-08 Plant Research International B.V. Mammalian-type glycosylation in plants
CA2434364C (en) 2001-01-19 2013-03-19 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
EP2319935B1 (en) 2002-03-19 2016-04-27 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants.
EP2339004B1 (en) 2002-03-19 2015-02-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
ATE426033T1 (de) 2003-08-11 2009-04-15 Greenovation Biotech Gmbh Promoter sequenzen aus moos und dessen verwendung
ES2395842T3 (es) 2006-01-17 2013-02-15 Synthon Biopharmaceuticals B.V. Composiciones y métodos para la humanización y optimización de N-glicanos en plantas
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
JP2009529898A (ja) * 2006-03-23 2009-08-27 バイエル・バイオサイエンス・エヌ・ヴェー Nicotianaβ−1,2−キシロシルトランスフェラーゼをコードする新規なヌクレオチド配列
NZ580510A (en) 2007-04-17 2011-06-30 Stichting Dienst Landbouwkundi Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
WO2008148223A1 (en) 2007-06-07 2008-12-11 Agriculture And Agri-Food Canada Nanocarrier based plant transfection and transduction
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2217328T3 (es) * 1995-11-23 2004-11-01 Cancer Research Campaign Technology Limited Materiales y procedimientos relacionados con la identificacion y secuenciacion del gen de susceptibilidad al cancer brca2 y utilizaciones del mismo.
WO1999029835A1 (en) * 1997-12-08 1999-06-17 Board Of Trustees Of The University Of Arkansas PURIFIED β1,2-XYLOSYLTRANSFERASE AND USES THEREOF
DE19754622A1 (de) † 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
EP1037990B8 (en) * 1997-12-19 2005-06-29 Pharmacia & Upjohn Company LLC Human sel-10 polypeptides and polynucleotides that encode them
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
AU5559499A (en) * 1998-08-11 2000-03-06 Darwin Discovery Limited Identification of the gene causing the mouse scurfy phenotype and its human ortholog
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
CA2388432A1 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants

Also Published As

Publication number Publication date
EP1263968B1 (en) 2005-12-14
DK1263968T3 (da) 2006-05-01
JP2013116113A (ja) 2013-06-13
DE60115863T3 (de) 2015-01-22
KR20100119005A (ko) 2010-11-08
JP5279976B2 (ja) 2013-09-04
KR100859919B1 (ko) 2008-09-23
US20040121325A1 (en) 2004-06-24
ES2460672T3 (es) 2014-05-14
EP1263968A1 (en) 2002-12-11
JP2004500096A (ja) 2004-01-08
US20070186311A1 (en) 2007-08-09
EP1263968B2 (en) 2014-09-10
CA2402015A1 (en) 2001-09-07
KR20080077296A (ko) 2008-08-21
KR20090101981A (ko) 2009-09-29
PT1621633E (pt) 2014-07-18
CA2402015C (en) 2012-07-17
WO2001064901A1 (en) 2001-09-07
KR20030030987A (ko) 2003-04-18
AT409381B (de) 2002-07-25
KR101185123B1 (ko) 2012-09-21
KR20070058018A (ko) 2007-06-07
AU781010B2 (en) 2005-04-28
US20120331578A1 (en) 2012-12-27
ES2252208T3 (es) 2006-05-16
ES2252208T5 (es) 2014-11-04
ATA3552000A (de) 2001-12-15
ATE312931T1 (de) 2005-12-15
KR100861437B1 (ko) 2008-10-02
DE60115863T2 (de) 2006-08-10
AU4649501A (en) 2001-09-12
EP1621633A3 (en) 2006-02-08
DK1621633T3 (da) 2014-05-19
EP1621633B1 (en) 2014-04-16
DE60115863D1 (de) 2006-01-19
US7205137B2 (en) 2007-04-17
EP1621633A2 (en) 2006-02-01

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