DK127165B - Fremgangsmåde til fremstilling af en alkalimetal- eller ammoniuminsulinforbindelse. - Google Patents

Fremgangsmåde til fremstilling af en alkalimetal- eller ammoniuminsulinforbindelse.

Info

Publication number: DK127165B
Authority: DK; Denmark
Prior art keywords: preparation; alkali metal; insulin compound; ammonium insulin; ammonium
Prior art date: 1969-12-05

Application number

DK191170AA

Other languages

English (en)

Inventor

R Jackson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-12-05

Filing date

1970-04-16

Publication date

1973-10-01

1970-04-16 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1973-10-01 Publication of DK127165B publication Critical patent/DK127165B/da

Links

102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229910052783 alkali metal Inorganic materials 0.000 title 1
150000001340 alkali metals Chemical class 0.000 title 1
-1 ammonium insulin compound Chemical class 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Substances N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C07K14/625—Extraction from natural sources
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/843—Digestive system
- Y10S530/845—Pancreas

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK191170AA 1969-12-05 1970-04-16 Fremgangsmåde til fremstilling af en alkalimetal- eller ammoniuminsulinforbindelse. DK127165B (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US88256369A	1969-12-05	1969-12-05

Publications (1)

Publication Number	Publication Date
DK127165B true DK127165B (da)	1973-10-01

Family

ID=25380854

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK191170AA DK127165B (da)	1969-12-05	1970-04-16	Fremgangsmåde til fremstilling af en alkalimetal- eller ammoniuminsulinforbindelse.

Country Status (8)

Country	Link
US (1)	US3719655A (da)
CA (1)	CA918565A (da)
DE (1)	DE2018588A1 (da)
DK (1)	DK127165B (da)
FR (1)	FR2045435A5 (da)
GB (1)	GB1269185A (da)
NL (1)	NL154423B (da)
SE (1)	SE371745B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3856771A (en) *	1973-07-16	1974-12-24	Lilly Co Eli	Process for manufacturing alkali metal or ammonium insulin
DE2505308A1 (de) *	1975-02-07	1976-08-19	Lilly Co Eli	Verfahren zur gewinnung von glucagon
WO1983003054A1 (en) *	1982-03-03	1983-09-15	Johansen, Kristian, Betton	A proces for producing an insulin preparation
DE3327709A1 (de) *	1983-07-29	1985-02-07	Hoechst Ag, 6230 Frankfurt	Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
US5504188A (en) *	1994-06-16	1996-04-02	Eli Lilly And Company	Preparation of stable zinc insulin analog crystals
US5597893A (en) *	1994-10-31	1997-01-28	Eli Lilly And Company	Preparation of stable insulin analog crystals
US6310038B1 (en) *	1997-03-20	2001-10-30	Novo Nordisk A/S	Pulmonary insulin crystals
ES2260832T3 (es) *	1997-03-20	2006-11-01	Novo Nordisk A/S	Cristales de insulina desprovistos de zinc utilizados en composiciones pulmonares.
US7741281B2 (en) *	2005-11-03	2010-06-22	Bristol-Myers Squibb Company	Hepatitis C virus inhibitors
US7714025B2 (en) *	2006-05-10	2010-05-11	Arizona Biomedical Research Commission	Modified chalcone compounds as antimitotic agents
ES2542146T3 (es)	2006-07-31	2015-07-31	Novo Nordisk A/S	Insulinas extendidas PEGiladas.
DK2074141T3 (da) *	2006-09-22	2016-11-28	Novo Nordisk As	Proteaseresistente insulinanaloger.
US9387176B2 (en) *	2007-04-30	2016-07-12	Novo Nordisk A/S	Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
WO2009112583A2 (en) *	2008-03-14	2009-09-17	Novo Nordisk A/S	Protease-stabilized insulin analogues
CN102037008B (zh)	2008-03-18	2016-08-31	诺沃-诺迪斯克有限公司	蛋白酶稳定化的、酰化胰岛素类似物
CN102219851B (zh) *	2011-05-09	2012-05-30	甘李药业有限公司	甘精胰岛素结晶的制备方法
US9481721B2 (en)	2012-04-11	2016-11-01	Novo Nordisk A/S	Insulin formulations
AU2014333979B2 (en)	2013-10-07	2018-02-15	Novo Nordisk A/S	Novel derivative of an insulin analogue
WO2016032869A1 (en)	2014-08-26	2016-03-03	Merck Sharp & Dohme Corp.	Method for preparing crystalline insulin or insulin analog compositions
TWI700091B (zh)	2016-12-16	2020-08-01	丹麥商諾佛儂迪克股份有限公司	含胰島素醫藥組成物
US12610742B2 (en)	2019-11-25	2026-04-21	Aita Bio Inc.	Micropump and method of fabricating the same

1969
- 1969-12-05 US US00882563A patent/US3719655A/en not_active Expired - Lifetime
1970
- 1970-03-20 CA CA077988A patent/CA918565A/en not_active Expired
- 1970-04-13 NL NL707005291A patent/NL154423B/xx not_active IP Right Cessation
- 1970-04-15 SE SE7005153A patent/SE371745B/xx unknown
- 1970-04-16 DK DK191170AA patent/DK127165B/da not_active IP Right Cessation
- 1970-04-17 DE DE19702018588 patent/DE2018588A1/de active Pending
- 1970-04-17 GB GB08470/70A patent/GB1269185A/en not_active Expired
- 1970-04-17 FR FR7014066A patent/FR2045435A5/fr not_active Expired

Also Published As

Publication number	Publication date
NL154423B (nl)	1977-09-15
GB1269185A (en)	1972-04-06
CA918565A (en)	1973-01-09
DE2018588A1 (de)	1971-06-09
SE371745B (da)	1974-12-02
FR2045435A5 (da)	1971-02-26
US3719655A (en)	1973-03-06
NL7005291A (da)	1971-06-08

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Legal Events

Date	Code	Title	Description
1990-05-28	PUP	Patent expired