DK128781B - Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. - Google Patents

Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Info

Publication number
DK128781B
DK128781B DK601570AA DK601570A DK128781B DK 128781 B DK128781 B DK 128781B DK 601570A A DK601570A A DK 601570AA DK 601570 A DK601570 A DK 601570A DK 128781 B DK128781 B DK 128781B
Authority
DK
Denmark
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
DK601570AA
Other languages
Danish (da)
English (en)
Inventor
E Woitun
W Reuter
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK128781B publication Critical patent/DK128781B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK601570AA 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. DK128781B (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen

Publications (1)

Publication Number Publication Date
DK128781B true DK128781B (da) 1974-07-01

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601570AA DK128781B (da) 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Country Status (13)

Country Link
US (1) US3661908A (ja)
BE (1) BE759493A (ja)
BG (2) BG17800A3 (ja)
CA (1) CA926865A (ja)
CH (3) CH559210A5 (ja)
DK (1) DK128781B (ja)
FR (1) FR2073416B1 (ja)
GB (1) GB1321316A (ja)
IE (1) IE34765B1 (ja)
IL (1) IL35729A (ja)
NL (1) NL7017210A (ja)
NO (1) NO129954B (ja)
SE (1) SE377938B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
TW200801012A (en) 2006-04-26 2008-01-01 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
TWI498332B (zh) * 2006-04-26 2015-09-01 Hoffmann La Roche 作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
WO2007129161A2 (en) * 2006-04-26 2007-11-15 F. Hoffmann-La Roche Ag Thieno [3, 2-d] pyrimidine derivative useful as pi3k inhibitor
RU2470936C2 (ru) * 2006-12-07 2012-12-27 Дженентек, Инк. Соединения-ингибиторы фосфоинозитид 3-киназы и способы применения
MX2009005950A (es) 2006-12-07 2009-10-12 Genentech Inc Compuestos inhibidores de fosfoinositido 3-quinasas y metodos de uso.
US7893060B2 (en) * 2007-06-12 2011-02-22 F. Hoffmann-La Roche Ag Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
CA2704711C (en) * 2007-09-24 2016-07-05 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
JP5348725B2 (ja) * 2007-10-25 2013-11-20 ジェネンテック， インコーポレイテッド チエノピリミジン化合物の製造方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
JP5709766B2 (ja) 2009-03-12 2015-04-30 ジェネンテック， インコーポレイテッド 造血器腫瘍の治療のためのホスホイノシチド３キナーゼ阻害剤化合物と化学療法剤の併用
BRPI1009022A2 (pt) * 2009-05-27 2016-03-08 Hoffmann La Roche "composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
US8158625B2 (en) * 2009-05-27 2012-04-17 Genentech, Inc. Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
CA2776944A1 (en) * 2009-10-12 2011-05-12 F. Hoffmann-La Roche Ag Combinations of a pi3k inhibitor and a mek inhibitor
WO2011130654A1 (en) 2010-04-16 2011-10-20 Genentech, Inc. Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
EP2959014B1 (en) 2013-02-25 2019-11-13 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant

Also Published As

Publication number Publication date
CH559210A5 (ja) 1975-02-28
BE759493A (fr) 1971-05-25
CH568324A5 (ja) 1975-10-31
IE34765B1 (en) 1975-08-06
NO129954B (ja) 1974-06-17
FR2073416A1 (ja) 1971-10-01
NL7017210A (ja) 1971-05-28
CA926865A (en) 1973-05-22
GB1321316A (en) 1973-06-27
BG17799A3 (bg) 1973-12-25
BG17800A3 (bg) 1973-12-25
FR2073416B1 (ja) 1975-04-18
US3661908A (en) 1972-05-09
IL35729A (en) 1974-01-14
IE34765L (en) 1971-05-26
IL35729A0 (en) 1971-01-28
CH567029A5 (ja) 1975-09-30
SE377938B (ja) 1975-08-04

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