DK1303302T3 - Anvendelse af stammer af parapox ovis virus mod organfibroser - Google Patents

Anvendelse af stammer af parapox ovis virus mod organfibroser

Info

Publication number: DK1303302T3
Authority: DK; Denmark
Prior art keywords: strains; organ fibrosis; virus against; fibrosis; against organ
Prior art date: 2000-07-11

Application number

DK01965110.8T

Other languages

English (en)

Inventor

Claudia Hirth-Dietrich

Tobias Schlapp

Angela Siegling

Andreas Knorr

Olaf Weber

Gudrun Theiss

Original Assignee

Aicuris Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-11

Filing date

2001-07-11

Publication date

2010-02-08

2001-07-11 Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg

2001-07-11 Priority claimed from PCT/EP2001/007978 external-priority patent/WO2002004019A2/de

2010-02-08 Application granted granted Critical

2010-02-08 Publication of DK1303302T3 publication Critical patent/DK1303302T3/da

Links

206010016654 Fibrosis Diseases 0.000 title abstract 3
230000004761 fibrosis Effects 0.000 title abstract 3
241000283898 Ovis Species 0.000 title 1
241000700605 Viruses Species 0.000 title 1
210000000056 organ Anatomy 0.000 title 1
239000003814 drug Substances 0.000 abstract 2
102000008186 Collagen Human genes 0.000 abstract 1
108010035532 Collagen Proteins 0.000 abstract 1
241000700639 Parapoxvirus Species 0.000 abstract 1
229920001436 collagen Polymers 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002828 effect on organs or tissue Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
210000004024 hepatic stellate cell Anatomy 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
230000009466 transformation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24211—Parapoxvirus, e.g. Orf virus
- C12N2710/24232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24211—Parapoxvirus, e.g. Orf virus
- C12N2710/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24211—Parapoxvirus, e.g. Orf virus
- C12N2710/24261—Methods of inactivation or attenuation
- C12N2710/24264—Methods of inactivation or attenuation by serial passage

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Addiction (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Dermatology (AREA)
Neurology (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Psychiatry (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK01965110.8T 2000-07-11 2001-07-11 Anvendelse af stammer af parapox ovis virus mod organfibroser DK1303302T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10033581		2000-07-11
DE10122233A DE10122233A1 (de)	2000-07-11	2001-05-08	Verwendung von Stämmen des Parapoxvirus ovis gegen Organfibrosen
PCT/EP2001/007978 WO2002004019A2 (de)	2000-07-11	2001-07-11	Verwendung von stämmen des parapoxvirus ovis gegen organfibrosen

Publications (1)

Publication Number	Publication Date
DK1303302T3 true DK1303302T3 (da)	2010-02-08

Family

ID=7648485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01965110.8T DK1303302T3 (da)	2000-07-11	2001-07-11	Anvendelse af stammer af parapox ovis virus mod organfibroser

Country Status (14)

Country	Link
JP (2)	JP5587950B2 (da)
KR (1)	KR100845643B1 (da)
CN (1)	CN101444539B (da)
AT (1)	ATE445413T1 (da)
BR (1)	BRPI0112411B8 (da)
DE (2)	DE10122233A1 (da)
DK (1)	DK1303302T3 (da)
DO (1)	DOP2001000210A (da)
EC (1)	ECSP034420A (da)
ES (1)	ES2332355T3 (da)
PE (1)	PE20020218A1 (da)
PT (1)	PT1303302E (da)
SV (1)	SV2002000527A (da)
ZA (1)	ZA200300276B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102015111756A1 (de) *	2015-07-20	2017-01-26	Eberhard Karls Universität Tübingen Medizinische Fakultät	Rekombinanter Orf-Virus-Vektor
AU2017221592A1 (en)	2016-02-16	2018-10-04	Osaka University	Pharmaceutical composition for use in treating fibrosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4405841C1 (de) *	1994-02-23	1995-01-05	Mayr Anton Prof Dr Med Vet Dr	Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DK0885013T3 (da) *	1996-04-15	2001-11-05	Anton Prof Dr Med Vet Dr Mayr	Anvendelse af multipotente paramunitetsinducere fra svækkede, ikke-immunogene poxvirus eller parapoxvirus til fremstilling af lægemidler

2001
- 2001-05-08 DE DE10122233A patent/DE10122233A1/de not_active Withdrawn
- 2001-07-10 PE PE2001000681A patent/PE20020218A1/es not_active Application Discontinuation
- 2001-07-11 KR KR1020037000310A patent/KR100845643B1/ko not_active Expired - Fee Related
- 2001-07-11 SV SV2001000527A patent/SV2002000527A/es not_active Application Discontinuation
- 2001-07-11 PT PT01965110T patent/PT1303302E/pt unknown
- 2001-07-11 DO DO2001000210A patent/DOP2001000210A/es unknown
- 2001-07-11 DK DK01965110.8T patent/DK1303302T3/da active
- 2001-07-11 CN CN200810149856.XA patent/CN101444539B/zh not_active Expired - Lifetime
- 2001-07-11 BR BRPI0112411-0 patent/BRPI0112411B8/pt not_active IP Right Cessation
- 2001-07-11 DE DE50115181T patent/DE50115181D1/de not_active Expired - Lifetime
- 2001-07-11 AT AT01965110T patent/ATE445413T1/de active
- 2001-07-11 ES ES01965110T patent/ES2332355T3/es not_active Expired - Lifetime
2003
- 2003-01-10 ZA ZA200300276A patent/ZA200300276B/en unknown
- 2003-01-10 EC EC2003004420A patent/ECSP034420A/es unknown
2012
- 2012-06-28 JP JP2012145847A patent/JP5587950B2/ja not_active Expired - Lifetime
2014
- 2014-06-17 JP JP2014124405A patent/JP5950964B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2014196329A (ja)	2014-10-16
DE10122233A1 (de)	2002-01-24
BR0112411A (pt)	2003-05-27
SV2002000527A (es)	2002-10-24
ES2332355T3 (es)	2010-02-03
JP2012214492A (ja)	2012-11-08
JP5950964B2 (ja)	2016-07-13
KR20030019562A (ko)	2003-03-06
ZA200300276B (en)	2004-04-13
PT1303302E (pt)	2009-11-11
CN101444539A (zh)	2009-06-03
BRPI0112411B1 (pt)	2018-02-27
DOP2001000210A (es)	2002-12-15
ECSP034420A (es)	2003-03-10
PE20020218A1 (es)	2002-05-19
DE50115181D1 (de)	2009-11-26
CN101444539B (zh)	2016-07-06
JP5587950B2 (ja)	2014-09-10
KR100845643B1 (ko)	2008-07-10
BRPI0112411B8 (pt)	2021-05-25
ATE445413T1 (de)	2009-10-15

Publication	Publication Date	Title
DK0693281T3 (da)	2001-05-21	Farmaceutiske fluoxetinformuleringer
ECSP045102A (es)	2004-06-28	Formulación farmacéutica que contiene 3-(3-dimetilamino-1-etil-2-metil-propil)fenol y proporciona una liberación retardada del ingrediente activo
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ATE514418T1 (de)	2011-07-15	Rasch zerfallende feste darreichungsformen mit nichtbröseliger konsistenz und pullulan
MXPA02012937A (es)	2004-07-30	Combinaciones de productos activos con propiedades insecticidas y acaricidas.
ATE291908T1 (de)	2005-04-15	Ibuprofen-wirkstoffzubereitung
CA2504872A1 (en)	2004-05-21	Use of resveratrol for the preparation of a medicament useful for the treatment of influenza virus infections
Vaillant	2000	Defense mechanisms.
AU2001235783A1 (en)	2001-09-12	Therapeutic compositions for pulmonary delivery
AR052044A1 (es)	2007-02-28	Composicion para el cuidado bucal y control del sarro que contiene extracto de magnolia
NO990440L (no)	1999-01-29	Preparat som innbefatter mupirocin og klorheksidin
WO2001057072A3 (en)	2002-10-31	Pharmacologically active antiviral peptides and methods of their use
PT1303302E (pt)	2009-11-11	Utilização de estirpes de parapoxvirus ovis contra fibroses de órgãos
MY130445A (en)	2007-06-29	Novel formulations of alpha-2, 4-disulfophenyl-n-tert-butylnitrone
NO20052960L (no)	2005-06-16	Anvendelse av dokosahekasensyre som aktivt stoff til behandling av lipodystrofi
WO2002004019A3 (de)	2002-08-01	Verwendung von stämmen des parapoxvirus ovis gegen organfibrosen
MXPA04005033A (es)	2004-08-11	Composicion farmaceutica que comprende una combinacion de metformina y acido 4-oxobutanoico y el uso de la misma para el tratamiento contra diabetes.
TR200200724T2 (tr)	2002-06-21	Cilde sürülebilen farmasötik bileşimlerin antimikrobik etkisinin arttırılması için yağlı asit/amino asit sabunlarının kullanımı
EP1038529A3 (en)	2002-05-02	Agent for increasing chemokine production
Vazquez	1996	How low can you go
Fox	2001	Stop Trying Too Hard to Kill Bacteria
MXPA04006269A (es)	2004-09-27	Composicion farmaceutica que comprende un inhibidor de alfa-glucosidasa y acido 4-oxobutanoico y uso de la misma para tratamiento de diabetes.
Hecht	1996	A new focus on primary HIV infection
NO992244L (no)	1999-07-07	AIDS-legemiddel
ES2130069B1 (es)	2000-03-01	Preparacion farmaceutica con liberacion retardada del producto activo.