DK130847B - Fremgangsmåde til fremstilling af et antibiotisk aktivt stof, der indeholder antibiotikum G-418, samt eventuelt verdamicin I, gentamicin A og sisomicin, de enkelte komponenter antibiotikum G-418 og eventuelt verdamicin I, gentamicin A og sisomicin eller salte eller Schiff-base-oxazolidin-derivater heraf. - Google Patents

Fremgangsmåde til fremstilling af et antibiotisk aktivt stof, der indeholder antibiotikum G-418, samt eventuelt verdamicin I, gentamicin A og sisomicin, de enkelte komponenter antibiotikum G-418 og eventuelt verdamicin I, gentamicin A og sisomicin eller salte eller Schiff-base-oxazolidin-derivater heraf.

Info

Publication number: DK130847B
Authority: DK; Denmark
Prior art keywords: antibiotic; verdamicin; gentamicin; optionally; sisomycin
Prior art date: 1971-11-08

Application number

DK407772AA

Other languages

Danish (da)

English (en)

Other versions

DK130847C (de

Inventor

M J Weinstein

G H Wagman

R Testa

J A Marquez

Original Assignee

Scherico Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-11-08

Filing date

1972-08-17

Publication date

1975-04-21

1972-08-17 Application filed by Scherico Ltd filed Critical Scherico Ltd

1975-04-21 Publication of DK130847B publication Critical patent/DK130847B/da

1975-09-29 Application granted granted Critical

1975-09-29 Publication of DK130847C publication Critical patent/DK130847C/da

Links

LKKVGKXCMYHKSL-LLZRLKDCSA-N gentamycin A Chemical compound O[C@H]1[C@H](NC)[C@@H](O)CO[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](N)C[C@H]1N LKKVGKXCMYHKSL-LLZRLKDCSA-N 0.000 title 4
BRZYSWJRSDMWLG-DJWUNRQOSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2s,3r,4r,5s,6r)-3-amino-4,5-dihydroxy-6-[(1r)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H]([C@@H](C)O)O2)N)[C@@H](N)C[C@H]1N BRZYSWJRSDMWLG-DJWUNRQOSA-N 0.000 title 2
XUSXOPRDIDWMFO-CTMSJIKGSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[[(2s,3r)-3-amino-6-[(1s)-1-aminoethyl]-3,4-dihydro-2h-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC=C(O2)[C@H](C)N)N)[C@@H](N)C[C@H]1N XUSXOPRDIDWMFO-CTMSJIKGSA-N 0.000 title 2
URWAJWIAIPFPJE-UHFFFAOYSA-N Rickamicin Natural products O1CC(O)(C)C(NC)C(O)C1OC1C(O)C(OC2C(CC=C(CN)O2)N)C(N)CC1N URWAJWIAIPFPJE-UHFFFAOYSA-N 0.000 title 2
XUSXOPRDIDWMFO-UHFFFAOYSA-N Verdamicin Natural products O1CC(O)(C)C(NC)C(O)C1OC1C(O)C(OC2C(CC=C(O2)C(C)N)N)C(N)CC1N XUSXOPRDIDWMFO-UHFFFAOYSA-N 0.000 title 2
URWAJWIAIPFPJE-YFMIWBNJSA-N sisomycin Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC=C(CN)O2)N)[C@@H](N)C[C@H]1N URWAJWIAIPFPJE-YFMIWBNJSA-N 0.000 title 2
229930192786 Sisomicin Natural products 0.000 title 1
239000013543 active substance Substances 0.000 title 1
239000003242 anti bacterial agent Substances 0.000 title 1
229940053194 antiepileptics oxazolidine derivative Drugs 0.000 title 1
230000003115 biocidal effect Effects 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
229960005456 sisomicin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK407772AA 1971-11-08 1972-08-17 Fremgangsmåde til fremstilling af et antibiotisk aktivt stof, der indeholder antibiotikum G-418, samt eventuelt verdamicin I, gentamicin A og sisomicin, de enkelte komponenter antibiotikum G-418 og eventuelt verdamicin I, gentamicin A og sisomicin eller salte eller Schiff-base-oxazolidin-derivater heraf. DK130847B (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US19670771A	1971-11-08	1971-11-08

Publications (2)

Publication Number	Publication Date
DK130847B true DK130847B (da)	1975-04-21
DK130847C DK130847C (de)	1975-09-29

Family

ID=22726520

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK407772AA DK130847B (da)	1971-11-08	1972-08-17	Fremgangsmåde til fremstilling af et antibiotisk aktivt stof, der indeholder antibiotikum G-418, samt eventuelt verdamicin I, gentamicin A og sisomicin, de enkelte komponenter antibiotikum G-418 og eventuelt verdamicin I, gentamicin A og sisomicin eller salte eller Schiff-base-oxazolidin-derivater heraf.

Country Status (20)

Country	Link
JP (1)	JPS4852991A (de)
AR (1)	AR193286A1 (de)
AT (1)	AT319469B (de)
BE (1)	BE787758A (de)
CA (1)	CA972303A (de)
CH (1)	CH586281A5 (de)
CS (1)	CS163282B2 (de)
DD (1)	DD102161A5 (de)
DE (1)	DE2239964A1 (de)
DK (1)	DK130847B (de)
FR (1)	FR2159246A1 (de)
IL (1)	IL40151A (de)
LU (1)	LU65922A1 (de)
NL (1)	NL7211265A (de)
NO (1)	NO136050C (de)
OA (1)	OA04260A (de)
PH (1)	PH13016A (de)
PL (1)	PL84893B1 (de)
RO (1)	RO58761A (de)
SE (1)	SE384691B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7313668A (de) *	1972-10-10	1974-04-16

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7012428A (de) *	1969-08-25	1971-03-01
CH551965A (de) *	1970-06-22	1974-07-31	Scherico Ltd	Verfahren zur herstellung antibiotisch wirksamer verbindungen.

0
- BE BE787758D patent/BE787758A/xx unknown
1972
- 1972-08-14 DE DE2239964A patent/DE2239964A1/de active Pending
- 1972-08-16 CH CH1211472A patent/CH586281A5/xx not_active IP Right Cessation
- 1972-08-17 NO NO2955/72A patent/NO136050C/no unknown
- 1972-08-17 RO RO71981A patent/RO58761A/ro unknown
- 1972-08-17 CS CS5710A patent/CS163282B2/cs unknown
- 1972-08-17 NL NL7211265A patent/NL7211265A/xx not_active Application Discontinuation
- 1972-08-17 SE SE7210703A patent/SE384691B/xx unknown
- 1972-08-17 PL PL1972157318A patent/PL84893B1/pl unknown
- 1972-08-17 DD DD165307A patent/DD102161A5/xx unknown
- 1972-08-17 CA CA149,843A patent/CA972303A/en not_active Expired
- 1972-08-17 PH PH13813A patent/PH13016A/en unknown
- 1972-08-17 IL IL40151A patent/IL40151A/en unknown
- 1972-08-17 FR FR7229471A patent/FR2159246A1/fr active Granted
- 1972-08-17 DK DK407772AA patent/DK130847B/da unknown
- 1972-08-17 AT AT712272A patent/AT319469B/de not_active IP Right Cessation
- 1972-08-18 JP JP47082680A patent/JPS4852991A/ja active Pending
- 1972-08-18 LU LU65922A patent/LU65922A1/xx unknown
- 1972-08-18 OA OA54666A patent/OA04260A/xx unknown
- 1972-08-18 AR AR243622A patent/AR193286A1/es active

Also Published As

Publication number	Publication date
FR2159246B1 (de)	1976-03-05
RO58761A (de)	1975-12-15
NO136050C (no)	1977-07-13
PL84893B1 (de)	1976-04-30
PH13016A (en)	1979-11-09
AT319469B (de)	1974-12-27
IL40151A (en)	1976-01-30
SE384691B (sv)	1976-05-17
BE787758A (fr)	1973-02-19
CA972303A (en)	1975-08-05
NL7211265A (de)	1973-05-10
DK130847C (de)	1975-09-29
JPS4852991A (de)	1973-07-25
DD102161A5 (de)	1973-12-05
CS163282B2 (de)	1975-08-29
IL40151A0 (en)	1972-10-29
DE2239964A1 (de)	1973-06-14
AR193286A1 (es)	1973-04-11
NO136050B (de)	1977-04-04
CH586281A5 (de)	1977-03-31
OA04260A (fr)	1979-12-31
LU65922A1 (de)	1973-01-15
FR2159246A1 (en)	1973-06-22

Similar Documents

Publication	Publication Date	Title
BR7107621D0 (pt)	1973-02-15	Um mancal aperfeicoado de roletes cilindricos
BR7306432D0 (pt)	1974-08-15	Conjunto de cremalheira e pinhao, e, conjunto de mancal
DK122735B (da)	1972-04-04	Fremgangsmåde til fremstilling af et antibakterielt virksomt stof, ambutyrosin, dets komponenter ambutyrosin A og B eller syreadditionssalte, eller tetra-N-acetylderivater eller tetra-N-methansulfonatderivater deraf.
DK128458B (da)	1974-05-06	Fremgangsmåde til fremstilling af et antibiotisk stof kaldet pyrazomycin.
DK127007B (da)	1973-09-10	Fremgangsmåde til fremstilling af de antibiotisk aktive stoffer SF-837, SF-837-A2, SF-837-A3 og SF-837-A4 eller blandinger, syreadditionssalte eller acetylderivater heraf.
DK132183B (da)	1975-11-03	Fremgangsmåde til fremstilling af et antibiotisk kompleks, benævnt A-25822, eller dets komponenter, benævnt A-25822 A, B, D, H, L, M og N eller syreadditionssalte deraf eller acetylderivatet af komponent A.
DK132504B (da)	1975-12-15	Fremgangsmåde til fremstilling af et antibiotisk kompleks kaldet Bu-1975, komponenter C1 og C2 deraf og syreadditionssalte heraf.
DK128017B (da)	1974-02-18	Fremgangsmåde til fremstilling af antibiotikum A 16886, dets komponenter A 16886I eller A 16886II eller salte heraf.
ES185939Y (es)	1974-08-16	Dispositivo de tope de puerta.
DK131791B (da)	1975-09-01	Fremgangsmåde til fremstilling af et antibiotisk aktivt produkt, dets bestanddele antibiotikum G-52 og sisomycin eller syreadditionssalte eller Schiffbaseoxazolidinderivater og/eller solvater heraf.
SE386031B (sv)	1976-07-26	Oscillator med mottakopplade komplementera transistorer
DK125025B (da)	1972-12-18	Analogifremgangsmåde til fremstilling af 2,1,3-benzothiadiazol-forbindelser eller salte deraf.
DK127931B (da)	1974-02-04	Fremgangsmåde til fremstilling af et antibiotikum betegnet negamycin eller salte heraf.
DK118712B (da)	1970-09-28	Fremgangsmåde til fremstilling af et antibiotisk stof, lincomycin B, eller salte heraf.
DK136910B (da)	1977-12-12	Fremgangsmåde til fremstilling af et antibiotisk stof gardimycin eller salte deraf.
DK111482B (da)	1968-09-02	Fremgangsmåde til fremstilling af et antibiotisk stof, lydimycin, eller salte deraf.
DK131041B (da)	1975-05-20	Fremgangsmåde til fremstilling af et antibiotikumkompleks.
DK129375B (da)	1974-10-07	Dyrefoder eller dyrefoderadditiv med et indhold af et antibiotisk aktivt stof.
DK130423B (da)	1975-02-17	Fremgangsmåde til fremstilling af et antibiotisk stof FR-1923 eller salte deraf.
SE384691B (sv)	1976-05-17	Framstellning av ett nytt antibiotikum g-418 samt ev. ett nytt antibiotikum verdamicin i och/eller de kenda gentamicin a resp. sisomicin genom odling av de hitills okenda micromonospora rhodorangea och m.m.
DK127008B (da)	1973-09-10	Fremgangsmåde til fremstilling af et antibiotisk aktivt stof betegnet Antibiotikum 67-694 eller salte heraf.
DK113565B (da)	1969-04-08	Fremgangsmåde til fremstilling af et antibiotisk stof, lincomycin D, eller salte deraf.
DK131578B (da)	1975-08-04	Fremgangsmåde til fremstilling af antibiotiket lincomycin.
DK117624C (da)	1970-10-19	Fremgangsmåde til fremstilling af et antibiotisk stof, lincomycin C, eller salte deraf.
DK127193B (da)	1973-10-01	Mikrobiologisk fremgangsmåde til fremstilling af antibiotiket lincomycin.