DK1315520T3 - Anvendelse af trifunktionelle bispecifikke og trispecifikke antistoffer til behandling af malign ascitis - Google Patents

Anvendelse af trifunktionelle bispecifikke og trispecifikke antistoffer til behandling af malign ascitis

Info

Publication number
DK1315520T3
DK1315520T3 DK01982241T DK01982241T DK1315520T3 DK 1315520 T3 DK1315520 T3 DK 1315520T3 DK 01982241 T DK01982241 T DK 01982241T DK 01982241 T DK01982241 T DK 01982241T DK 1315520 T3 DK1315520 T3 DK 1315520T3
Authority
DK
Denmark
Prior art keywords
ascitis
trispecific antibodies
trifunctional bispecific
binding
treat malignant
Prior art date
Application number
DK01982241T
Other languages
Danish (da)
English (en)
Inventor
Horst Dr Lindhofer
Original Assignee
Horst Dr Lindhofer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Horst Dr Lindhofer filed Critical Horst Dr Lindhofer
Application granted granted Critical
Publication of DK1315520T3 publication Critical patent/DK1315520T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK01982241T 2000-09-04 2001-09-04 Anvendelse af trifunktionelle bispecifikke og trispecifikke antistoffer til behandling af malign ascitis DK1315520T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10043437A DE10043437A1 (de) 2000-09-04 2000-09-04 Verwendung von trifunktionellen bispezifischen und trispezifischen Antikörpern zur Behandlung von malignem Aszites
EP01982241A EP1315520B1 (fr) 2000-09-04 2001-09-04 Utilisation d'anticorps trifonctionnels bispecifiques et trispecifiques dans le traitement d'ascites malignes
PCT/EP2001/010184 WO2002020039A2 (fr) 2000-09-04 2001-09-04 Utilisation d'anticorps trifonctionnels bispecifiques et trispecifiques dans le traitement d'ascites malignes

Publications (1)

Publication Number Publication Date
DK1315520T3 true DK1315520T3 (da) 2005-08-22

Family

ID=7654853

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01982241T DK1315520T3 (da) 2000-09-04 2001-09-04 Anvendelse af trifunktionelle bispecifikke og trispecifikke antistoffer til behandling af malign ascitis

Country Status (10)

Country Link
US (2) US8277806B2 (fr)
EP (1) EP1315520B1 (fr)
AT (1) ATE294591T1 (fr)
DE (3) DE10043437A1 (fr)
DK (1) DK1315520T3 (fr)
ES (1) ES2241887T3 (fr)
LU (1) LU91616I2 (fr)
NL (1) NL300418I1 (fr)
PT (1) PT1315520E (fr)
WO (1) WO2002020039A2 (fr)

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DE19859110A1 (de) * 1998-09-25 2000-04-13 Horst Lindhofer Bispezifische und trispezifische Antikörper, die spezifisch mit induzierbaren Oberflächenantigenen als operationelle Zielstrukturen reagieren
US20020022017A1 (en) * 2000-04-12 2002-02-21 Hua Yu Regulation of systemic immune responses utilizing soluble CD40

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WO2002020039A3 (fr) 2002-07-25
EP1315520A2 (fr) 2003-06-04
US20130095106A1 (en) 2013-04-18
US8277806B2 (en) 2012-10-02
NL300418I1 (nl) 2010-01-04
EP1315520B1 (fr) 2005-05-04
ATE294591T1 (de) 2005-05-15
DE10043437A1 (de) 2002-03-28
DE122009000069I1 (de) 2010-01-21
WO2002020039A2 (fr) 2002-03-14
US20030223999A1 (en) 2003-12-04
DE50106127D1 (de) 2005-06-09
ES2241887T3 (es) 2005-11-01
LU91616I2 (fr) 2009-12-16
PT1315520E (pt) 2005-09-30

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