DK1339409T3 - Anvendelse af rosuvastatin (ZD-4522) til behandling af heterozygot, familiær hypercholesterolæmi - Google Patents

Anvendelse af rosuvastatin (ZD-4522) til behandling af heterozygot, familiær hypercholesterolæmi

Info

Publication number: DK1339409T3
Authority: DK; Denmark
Prior art keywords: rosuvastatin; treatment; familial hypercholesterolemia; heterozygous familial; heterozygous
Prior art date: 2000-11-22

Application number

DK01982623T

Other languages

Danish (da)

English (en)

Inventor

Ali Raza

Howard Gerard Hutchinson

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-22

Filing date

2001-11-16

Publication date

2008-09-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9903629&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1339409(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-11-16 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2008-09-08 Application granted granted Critical

2008-09-08 Publication of DK1339409T3 publication Critical patent/DK1339409T3/da

Links

206010045261 Type IIa hyperlipidaemia Diseases 0.000 title 1
BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title 1
229960000672 rosuvastatin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Obesity (AREA)
Hematology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK01982623T 2000-11-22 2001-11-16 Anvendelse af rosuvastatin (ZD-4522) til behandling af heterozygot, familiær hypercholesterolæmi DK1339409T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0028429.9A GB0028429D0 (en)	2000-11-22	2000-11-22	Therapy
PCT/GB2001/005041 WO2002041895A1 (en)	2000-11-22	2001-11-16	Use of rosuvastatin (zd-4522) in the treatment of heterozygous familial hypercholesterolemia

Publications (1)

Publication Number	Publication Date
DK1339409T3 true DK1339409T3 (da)	2008-09-08

Family

ID=9903629

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01982623T DK1339409T3 (da)	2000-11-22	2001-11-16	Anvendelse af rosuvastatin (ZD-4522) til behandling af heterozygot, familiær hypercholesterolæmi

Country Status (34)

Country	Link
US (1)	US6858618B2 (cs)
EP (1)	EP1339409B1 (cs)
JP (2)	JP5062940B2 (cs)
KR (1)	KR100815042B1 (cs)
CN (1)	CN1268339C (cs)
AR (1)	AR031766A1 (cs)
AT (1)	ATE394103T1 (cs)
AU (2)	AU1416502A (cs)
BG (1)	BG66009B1 (cs)
BR (1)	BR0115511A (cs)
CA (1)	CA2429263C (cs)
CY (1)	CY1110428T1 (cs)
CZ (1)	CZ301583B6 (cs)
DE (1)	DE60133921D1 (cs)
DK (1)	DK1339409T3 (cs)
EE (1)	EE05507B1 (cs)
ES (1)	ES2305118T3 (cs)
GB (1)	GB0028429D0 (cs)
HU (1)	HUP0301380A3 (cs)
IL (2)	IL155919A0 (cs)
IS (1)	IS6819A (cs)
MX (1)	MXPA03004336A (cs)
MY (1)	MY134902A (cs)
NO (1)	NO326245B1 (cs)
NZ (1)	NZ525754A (cs)
PL (1)	PL365386A1 (cs)
PT (1)	PT1339409E (cs)
RU (1)	RU2294744C2 (cs)
SI (1)	SI1339409T1 (cs)
SK (1)	SK6212003A3 (cs)
TW (1)	TWI238720B (cs)
UA (1)	UA75614C2 (cs)
WO (1)	WO2002041895A1 (cs)
ZA (1)	ZA200303636B (cs)

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GB0003305D0 (en) *	2000-02-15	2000-04-05	Zeneca Ltd	Pyrimidine derivatives
US20090247488A1 (en) *	2003-04-25	2009-10-01	Carina Cannizzaro	Anti-inflammatory phosphonate compounds
US7470724B2 (en) *	2003-04-25	2008-12-30	Gilead Sciences, Inc.	Phosphonate compounds having immuno-modulatory activity
US7452901B2 (en) *	2003-04-25	2008-11-18	Gilead Sciences, Inc.	Anti-cancer phosphonate analogs
JP2006524710A (ja) *	2003-04-25	2006-11-02	ギリアードサイエンシーズ，インコーポレイテッド	キナーゼインヒビターホスホネート抱合体
US20050261237A1 (en) *	2003-04-25	2005-11-24	Boojamra Constantine G	Nucleoside phosphonate analogs
US7407965B2 (en) *	2003-04-25	2008-08-05	Gilead Sciences, Inc.	Phosphonate analogs for treating metabolic diseases
PL1628685T3 (pl)	2003-04-25	2011-05-31	Gilead Sciences Inc	Przeciwwirusowe analogi fosfonianowe
CA2537271A1 (en) *	2003-08-28	2005-03-17	Teva Pharmaceutical Industries, Ltd.	Process for preparation of rosuvastatin calcium
GB0322552D0 (en)	2003-09-26	2003-10-29	Astrazeneca Uk Ltd	Therapeutic treatment
WO2005044308A1 (en) *	2003-10-24	2005-05-19	Gilead Sciences, Inc.	Phosphonate analogs of antimetabolites
WO2005051921A1 (en)	2003-11-24	2005-06-09	Teva Pharmaceutical Industries Ltd.	Crystalline ammonium salts of rosuvastatin
KR100887264B1 (ko) *	2003-12-02	2009-03-06	테바 파마슈티컬 인더스트리즈 리미티드	로수바스타틴의 특성화를 위한 기준 표준물
US7851624B2 (en) *	2003-12-24	2010-12-14	Teva Pharamaceutical Industries Ltd.	Triol form of rosuvastatin and synthesis of rosuvastatin
US20070179166A1 (en) *	2003-12-24	2007-08-02	Valerie Niddam-Hildesheim	Process for preparation of statins with high syn to anti ratio
CA2567963A1 (en) *	2004-05-26	2005-12-08	Kgk Synergize Inc.	Functional foods comprising flavonoids and tocotrienols and methods thereof
US7179916B2 (en) *	2004-07-13	2007-02-20	Teva Pharmaceutical Industries Ltd.	Process for the preparation of rosuvastatin
EP1778251B1 (en)	2004-07-27	2011-04-13	Gilead Sciences, Inc.	Nucleoside phosphonate conjugates as anti hiv agents
US20070167625A1 (en) *	2005-02-22	2007-07-19	Anna Balanov	Preparation of rosuvastatin
CA2683975A1 (en) *	2005-02-22	2006-08-31	Teva Pharmaceutical Industries Ltd.	Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
US20070037979A1 (en) *	2005-02-22	2007-02-15	Valerie Niddam-Hildesheim	Preparation of rosuvastatin
US7868169B2 (en) *	2005-08-16	2011-01-11	Teva Pharmaceutical Industries, Ltd.	Crystalline rosuvastatin intermediate
US8383614B2 (en) *	2008-01-31	2013-02-26	The Trustees Of The University Of Pennsylvania	Hypercholestrolemia and tendinous injuries
US9427437B2 (en)	2008-01-31	2016-08-30	The Trustees Of The University Of Pennsylvania	Hypercholesterolemia and tendinous injuries
EP2298745B1 (en)	2008-05-27	2014-09-03	Changzhou Pharmaceutical Factory	Preparation method of rosuvastatin calcium and its intermediates
AU2009268681B2 (en) *	2008-07-08	2014-10-02	Gilead Sciences, Inc.	Salts of HIV inhibitor compounds
CA2884481C (en)	2012-09-17	2021-04-27	Madrigal Pharmaceuticals, Inc.	Method of synthesizing thyroid hormone analogs and polymorphs thereof
US9132117B2 (en)	2013-06-17	2015-09-15	Kgk Synergize, Inc	Compositions and methods for glycemic control of subjects with impaired fasting glucose
US10600502B2 (en)	2016-12-20	2020-03-24	Astrazeneca Uk Ltd.	Systems and methods for dispensing a statin medication over the counter
EP3661937B1 (en)	2017-08-01	2021-07-28	Gilead Sciences, Inc.	Crystalline forms of ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate (gs-9131) for treating viral infections
MA56036A (fr)	2019-05-27	2022-04-06	Immatics Us Inc	Vecteurs viraux et leur utilisation dans une thérapie cellulaire adoptive
DE102020111571A1 (de)	2020-03-11	2021-09-16	Immatics US, Inc.	Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
US20220008519A1 (en)	2020-07-09	2022-01-13	Costa Rican Social Security Fund / Caja Costarricense de Seguro Social (CCSS)	Treatment of severe acute respiratory syndrome-related coronavirus infection with klotho
US20220056411A1 (en)	2020-08-21	2022-02-24	Immatics US, Inc.	Methods for isolating cd8+ selected t cells
WO2022165227A1 (en) *	2021-02-01	2022-08-04	Madrigal Pharmaceuticals, Inc.	Therapeutic combinations of rosuvastatin and resmetirom for the treatment of liver disorders or lipid disorders
US12377104B1 (en)	2024-02-06	2025-08-05	Madrigal Pharmaceuticals, Inc.	Methods for treating a fatty liver disease

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2051907C1 (ru) *	1989-05-22	1996-01-10	Сандос АГ	Способ получения 7-замещенной гептен-6-овой кислоты
JP2648897B2 (ja) *	1991-07-01	1997-09-03	塩野義製薬株式会社	ピリミジン誘導体
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US6369103B1 (en) *	1994-01-18	2002-04-09	Bristol-Myers Squibb Company	Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
GB0001621D0 (en) *	2000-01-26	2000-03-15	Astrazeneca Ab	Pharmaceutical compositions
EP1322289B1 (en) *	2000-09-20	2007-07-25	Jagotec AG	Spray drying process of compositions containing fenofibrate

2000
- 2000-11-22 GB GBGB0028429.9A patent/GB0028429D0/en not_active Ceased
2001
- 2001-11-16 PT PT01982623T patent/PT1339409E/pt unknown
- 2001-11-16 US US10/432,402 patent/US6858618B2/en not_active Expired - Lifetime
- 2001-11-16 AT AT01982623T patent/ATE394103T1/de active
- 2001-11-16 HU HU0301380A patent/HUP0301380A3/hu not_active Application Discontinuation
- 2001-11-16 CA CA002429263A patent/CA2429263C/en not_active Expired - Fee Related
- 2001-11-16 EE EEP200300239A patent/EE05507B1/xx not_active IP Right Cessation
- 2001-11-16 SK SK621-2003A patent/SK6212003A3/sk not_active Application Discontinuation
- 2001-11-16 ES ES01982623T patent/ES2305118T3/es not_active Expired - Lifetime
- 2001-11-16 IL IL15591901A patent/IL155919A0/xx unknown
- 2001-11-16 EP EP01982623A patent/EP1339409B1/en not_active Revoked
- 2001-11-16 DE DE60133921T patent/DE60133921D1/de not_active Expired - Lifetime
- 2001-11-16 AU AU1416502A patent/AU1416502A/xx active Pending
- 2001-11-16 AU AU2002214165A patent/AU2002214165B9/en not_active Revoked
- 2001-11-16 DK DK01982623T patent/DK1339409T3/da active
- 2001-11-16 JP JP2002544073A patent/JP5062940B2/ja not_active Expired - Lifetime
- 2001-11-16 NZ NZ525754A patent/NZ525754A/en not_active IP Right Cessation
- 2001-11-16 BR BR0115511-3A patent/BR0115511A/pt not_active Application Discontinuation
- 2001-11-16 SI SI200130839T patent/SI1339409T1/sl unknown
- 2001-11-16 WO PCT/GB2001/005041 patent/WO2002041895A1/en not_active Ceased
- 2001-11-16 CZ CZ20031406A patent/CZ301583B6/cs not_active IP Right Cessation
- 2001-11-16 PL PL01365386A patent/PL365386A1/xx not_active Application Discontinuation
- 2001-11-16 MX MXPA03004336A patent/MXPA03004336A/es unknown
- 2001-11-16 UA UA2003054394A patent/UA75614C2/uk unknown
- 2001-11-16 RU RU2003114300/15A patent/RU2294744C2/ru not_active IP Right Cessation
- 2001-11-16 KR KR1020037006791A patent/KR100815042B1/ko not_active Ceased
- 2001-11-16 CN CNB018221599A patent/CN1268339C/zh not_active Expired - Lifetime
- 2001-11-20 MY MYPI20015303A patent/MY134902A/en unknown
- 2001-11-21 TW TW090128858A patent/TWI238720B/zh not_active IP Right Cessation
- 2001-11-22 AR ARP010105452A patent/AR031766A1/es unknown
2003
- 2003-05-12 ZA ZA200303636A patent/ZA200303636B/en unknown
- 2003-05-13 BG BG107811A patent/BG66009B1/bg unknown
- 2003-05-14 IL IL155919A patent/IL155919A/en unknown
- 2003-05-19 IS IS6819A patent/IS6819A/is unknown
- 2003-05-21 NO NO20032292A patent/NO326245B1/no not_active IP Right Cessation
2008
- 2008-07-07 CY CY20081100703T patent/CY1110428T1/el unknown
2009
- 2009-11-09 JP JP2009255813A patent/JP2010031047A/ja active Pending

Also Published As

Publication number	Publication date
CZ301583B6 (cs)	2010-04-21
SK6212003A3 (en)	2003-11-04
KR100815042B1 (ko)	2008-03-18
BR0115511A (pt)	2003-12-30
KR20030048479A (ko)	2003-06-19
ATE394103T1 (de)	2008-05-15
HK1056691A1 (en)	2004-02-27
CZ20031406A3 (cs)	2003-09-17
CN1630520A (zh)	2005-06-22
US20040072852A1 (en)	2004-04-15
JP2004522714A (ja)	2004-07-29
CY1110428T1 (el)	2015-04-29
MY134902A (en)	2007-12-31
JP5062940B2 (ja)	2012-10-31
EE05507B1 (et)	2012-02-15
ZA200303636B (en)	2004-08-12
PT1339409E (pt)	2008-07-07
BG107811A (bg)	2004-03-31
RU2294744C2 (ru)	2007-03-10
ES2305118T3 (es)	2008-11-01
AU1416502A (en)	2002-06-03
SI1339409T1 (sl)	2008-08-31
NO20032292L (no)	2003-07-17
AU2002214165B9 (en)	2013-07-04
HUP0301380A3 (en)	2007-03-28
EP1339409B1 (en)	2008-05-07
CA2429263A1 (en)	2002-05-30
EE200300239A (et)	2003-08-15
AU2002214165B2 (en)	2006-12-14
BG66009B1 (bg)	2010-10-29
EP1339409A1 (en)	2003-09-03
IL155919A0 (en)	2003-12-23
GB0028429D0 (en)	2001-01-10
DE60133921D1 (de)	2008-06-19
NO20032292D0 (no)	2003-05-21
PL365386A1 (en)	2005-01-10
TWI238720B (en)	2005-09-01
MXPA03004336A (es)	2003-08-19
IL155919A (en)	2009-09-01
JP2010031047A (ja)	2010-02-12
CN1268339C (zh)	2006-08-09
NZ525754A (en)	2004-10-29
NO326245B1 (no)	2008-10-27
HUP0301380A2 (hu)	2003-10-28
IS6819A (is)	2003-05-19
UA75614C2 (uk)	2006-05-15
WO2002041895A1 (en)	2002-05-30
US6858618B2 (en)	2005-02-22
CA2429263C (en)	2009-03-17
AR031766A1 (es)	2003-10-01

Publication	Publication Date	Title
MXPA03004336A (es)	2003-08-19	Uso de rosuvastatin (zd-4522) en el tratamiento de hipercolesterolemia familar heterocigotica.
NO20030795L (no)	2003-04-04	Kinazolinderivater
ATE464068T1 (de)	2010-04-15	Antikörper gegen opgl
DK1259512T3 (da)	2003-12-29	Pteridinforbindelser til behandling af psoreasis
FI20010694A0 (fi)	2001-04-03	Implantti
NO20035573L (no)	2004-02-16	Kinazolinderivater
NO20041840L (no)	2004-05-05	Rosuvastatin ved predemente tilstander
DK1461042T3 (da)	2008-12-01	Anvendelse af desoxypeganin til behandling af klinisk depression
DK1493442T3 (da)	2005-12-19	Reboxetin til behandling af perifer neuropati
ITTO20000776A0 (it)	2000-08-04	Ventilatore filtrante.
EE200300563A (et)	2004-02-16	Bensüülaminopürimidiiniühendid, nende kasutamine ja ravim
ES1043922Y (es)	2000-08-01	Filtro nasal.
IT1307028B1 (it)	2001-10-23	Bendaggio.
DK1267849T3 (da)	2005-06-20	Begrænsning af genoptagelse af lægemiddelanvendelse
ES1050786Y (es)	2002-09-16	Monedero polivalente.
ITTO20010239U1 (it)	2003-06-23	Portamonete.
ITTO20010243V0 (it)	2001-12-28	Portamonete.
ITTO20010096U1 (it)	2002-12-18	Siringa.
ES1048887Y (es)	2002-02-16	Conjunto dispensador de infusiones de uso publico y/o privado.
ITIS20000001U1 (it)	2001-08-21	Bicchiere monouso identificabile.
FI20010889A7 (fi)	2002-10-28	Tasomainen värähtelijä
FI3963U1 (fi)	1999-05-19	Tii
ES1049553Y (es)	2002-09-01	Portamonedas
ITGE20010012V0 (it)	2001-04-27	Portamonete
BR0106350B1 (pt)	2009-12-01	aperfeiçoamento introduzido em seringa descartável.