DK134601B - Analogifremgangsmåde til fremstilling af benzylimidazolidioner. - Google Patents

Analogifremgangsmåde til fremstilling af benzylimidazolidioner.

Info

Publication number
DK134601B
DK134601B DK83171AA DK83171A DK134601B DK 134601 B DK134601 B DK 134601B DK 83171A A DK83171A A DK 83171AA DK 83171 A DK83171 A DK 83171A DK 134601 B DK134601 B DK 134601B
Authority
DK
Denmark
Prior art keywords
benzylimidazolide
ions
preparation
analogous process
analogous
Prior art date
Application number
DK83171AA
Other languages
Danish (da)
English (en)
Other versions
DK134601C (fr
Inventor
Vsevolod Gruenman
Max Hoffer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK134601B publication Critical patent/DK134601B/da
Application granted granted Critical
Publication of DK134601C publication Critical patent/DK134601C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK83171AA 1970-02-24 1971-02-24 Analogifremgangsmåde til fremstilling af benzylimidazolidioner. DK134601B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1376970A 1970-02-24 1970-02-24

Publications (2)

Publication Number Publication Date
DK134601B true DK134601B (da) 1976-12-06
DK134601C DK134601C (fr) 1977-05-16

Family

ID=21761656

Family Applications (2)

Application Number Title Priority Date Filing Date
DK83171AA DK134601B (da) 1970-02-24 1971-02-24 Analogifremgangsmåde til fremstilling af benzylimidazolidioner.
DK570075A DK570075A (da) 1970-02-24 1975-12-15 Benzylimidazolidinoner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK570075A DK570075A (da) 1970-02-24 1975-12-15 Benzylimidazolidinoner

Country Status (18)

Country Link
US (1) US3636039A (fr)
JP (1) JPS5421338B1 (fr)
BE (1) BE763298A (fr)
BR (1) BR7101125D0 (fr)
CA (1) CA967163A (fr)
CH (2) CH567482A5 (fr)
DE (1) DE2108438C2 (fr)
DK (2) DK134601B (fr)
FI (1) FI54919C (fr)
FR (1) FR2081537B1 (fr)
GB (1) GB1292768A (fr)
IE (1) IE35283B1 (fr)
IL (1) IL36237A (fr)
NL (1) NL171446C (fr)
NO (1) NO130680C (fr)
SE (1) SE369190B (fr)
YU (1) YU34407B (fr)
ZA (1) ZA711077B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones
US3966758A (en) * 1975-06-16 1976-06-29 Morton-Norwich Products, Inc. Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones
US4063022A (en) * 1976-11-22 1977-12-13 Morton-Norwich Products, Inc. Antisecretory 2-imidazolidinones
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
CA1188616A (fr) * 1981-06-11 1985-06-11 Hoffmann-La Roche Limited Preparations pharmaceutiques
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
JP2001523213A (ja) * 1994-12-13 2001-11-20 ユーロ−セルティーク，エス．エイ． 三置換チオキサンチン類
EP0814809B1 (fr) * 1994-12-13 2003-08-13 Euroceltique S.A. Aryle thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
WO2001068600A2 (fr) 2000-03-16 2001-09-20 Inflazyme Pharmaceuticals Limited Inhibiteurs benzyles de pde4
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
MX2009013293A (es) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (fr) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles
CA2730603C (fr) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonistes de la guanylate cyclase utiles dans le traitement des affections gastro-intestinales, de l'inflammation gastro-intestinale, du cancer gastro-intestinal et d'autres affections
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA3100941C (fr) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Procede de preparation d'agonistes du guanylate cyclase c
EP3718557A3 (fr) 2013-02-25 2020-10-21 Bausch Health Ireland Limited Agoniste du récepteur de la guanylate cyclase sp-333 à utiliser lors du nettoyage du côlon
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
KR20160042039A (ko) 2013-08-09 2016-04-18 알데릭스, 인코포레이티드 인산염 수송을 억제하기 위한 화합물 및 방법
WO2020237096A1 (fr) 2019-05-21 2020-11-26 Ardelyx, Inc. Combinaison pour baisser le phosphate sérique chez un patient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518285A (de) * 1968-05-01 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen

Also Published As

Publication number Publication date
DK134601C (fr) 1977-05-16
YU43971A (en) 1978-12-31
US3636039A (en) 1972-01-18
CH567482A5 (fr) 1975-10-15
GB1292768A (en) 1972-10-11
IL36237A0 (en) 1971-04-28
NL171446B (nl) 1982-11-01
CH567483A5 (fr) 1975-10-15
FI54919C (fi) 1979-04-10
IE35283B1 (en) 1976-01-07
ZA711077B (en) 1971-10-27
BE763298A (fr) 1971-08-23
NL7102324A (fr) 1971-08-26
CA967163A (en) 1975-05-06
BR7101125D0 (pt) 1973-04-26
DE2108438C2 (de) 1987-02-05
FR2081537B1 (fr) 1974-08-23
FR2081537A1 (fr) 1971-12-03
IE35283L (en) 1971-08-24
NO130680C (fr) 1975-01-22
DE2108438A1 (de) 1971-09-09
NL171446C (nl) 1983-04-05
IL36237A (en) 1974-11-29
YU34407B (en) 1979-07-10
JPS5421338B1 (fr) 1979-07-30
DK570075A (da) 1975-12-15
SE369190B (fr) 1974-08-12
NO130680B (fr) 1974-10-14
FI54919B (fi) 1978-12-29

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