DK13485A - Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie - Google Patents

Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie Download PDF

Info

Publication number
DK13485A
DK13485A DK13485A DK13485A DK13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A DK 13485 A DK13485 A DK 13485A
Authority
DK
Denmark
Prior art keywords
monoclonal antibodies
cell line
factor viiic
december
deposited
Prior art date
Application number
DK13485A
Other languages
English (en)
Other versions
DK13485D0 (da
Inventor
George Kuo
Frank R Masiarz
Martha Truett
Pablo Valenzuela
Mirella Ezban Rasmussen
Jennifer Favaloro
Original Assignee
Chiron Corp
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/570,062 external-priority patent/US5004804A/en
Priority claimed from US06/689,274 external-priority patent/US4716117A/en
Application filed by Chiron Corp, Nordisk Gentofte filed Critical Chiron Corp
Publication of DK13485D0 publication Critical patent/DK13485D0/da
Publication of DK13485A publication Critical patent/DK13485A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK13485A 1984-01-12 1985-01-11 Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie DK13485A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/570,062 US5004804A (en) 1984-01-12 1984-01-12 Method and composition for preparation of factor VIIIC
US66491984A 1984-10-26 1984-10-26
US06/689,274 US4716117A (en) 1984-10-26 1985-01-07 Monoclonal antibodies to factor VIIIC

Publications (2)

Publication Number Publication Date
DK13485D0 DK13485D0 (da) 1985-01-11
DK13485A true DK13485A (da) 1985-07-13

Family

ID=27416093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13485A DK13485A (da) 1984-01-12 1985-01-11 Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie

Country Status (5)

Country Link
EP (2) EP0152746B1 (da)
JP (2) JPH0764879B2 (da)
AT (1) ATE66249T1 (da)
DE (2) DE152746T1 (da)
DK (1) DK13485A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
DD298055A5 (de) * 1989-09-14 1992-02-06 ����������@�����������@���Kk�� Methode und nuetzlicher apparat zur darstellung pharmazeutischer zusammensetzungen
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
AT404429B (de) * 1995-06-09 1998-11-25 Immuno Ag Anti-plasma-antikörper-präparation
PT1095143E (pt) * 1998-05-08 2008-11-28 Sanquin Bloedvoorziening Inibidor para o diagnóstico e tratamento de doentes com hemofilia a
TWI452136B (zh) 2010-11-17 2014-09-11 中外製藥股份有限公司 A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation
TWI701435B (zh) * 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定ｆｖｉｉｉ的反應性之方法
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
CR20180554A (es) 2016-04-28 2019-01-10 Chugai Pharmaceutical Co Ltd Preparaciones que contienen anticuerpos
CN110461358A (zh) 2017-03-31 2019-11-15 公立大学法人奈良县立医科大学 可用于预防和/或治疗凝血因子ⅸ异常、包含代替凝血因子ⅷ的功能的多特异性抗原结合分子的药物组合物
CN119161488A (zh) 2017-11-01 2024-12-20 中外制药株式会社 具有降低的生物活性的抗体变体和同种型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
IE80638B1 (en) * 1983-03-31 1998-10-21 Scripps Research Inst Monoclonal antibodies to new factor VIII coagulant polypeptides

Also Published As

Publication number Publication date
DE3583750D1 (de) 1991-09-19
EP0432134A1 (en) 1991-06-12
JPH0817697B2 (ja) 1996-02-28
JPH0764879B2 (ja) 1995-07-12
EP0152746A2 (en) 1985-08-28
EP0152746A3 (en) 1987-05-27
ATE66249T1 (de) 1991-08-15
JPS60210981A (ja) 1985-10-23
JPH0678761A (ja) 1994-03-22
DE152746T1 (de) 1986-04-10
EP0152746B1 (en) 1991-08-14
DK13485D0 (da) 1985-01-11

Similar Documents

Publication Publication Date Title
EP0642668B1 (en) Nuclear matrix protein fluid assay
JP2617289B2 (ja) モノクローナル抗体生産性ハイブリドマ細胞系
CA1248471A (en) Immunoassay for breast cancer employing monoclonal antibodies
DK13485A (da) Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie
DE3278203D1 (en) Monoclonal antibodies specific for the human transferrin receptor glycoprotein
US5185432A (en) Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas
Naessens et al. De novo expression of T cell markers on Theileria parva-transformed lymphoblasts in cattle.
IL116617A0 (en) Monoclonal antibodies specific for advanced glycosylation endproducts in biological samples
US5084380A (en) Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
AU599578B2 (en) Monoclonal antibodies and antigens for human non-small cell lung carcinomas
CA1297048C (en) Monoclonal antibodies reactive with normal and oncogenic forms of the ras p21 protein
KR900007430A (ko) 항-퓨코실세르아미드 모노클로날 항체
US4898932A (en) Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
DE69619226T2 (de) Monoklonaler antikörper gegen den komplex aus faktor xa und dem inhibitor für den gewebefaktor (xa. tfpi)
DE59511090D1 (de) Monoklonale Antikörper zur selektiven immunologischen Bestimmung von hochmolekularen, intakten Lamininformen in Körperflüssigkeiten
Bollum et al. Monoclonal antibodies to human terminal transferase.
DE3685145D1 (de) Monoklonale antikoerper gegen atriale, natriurethische peptide.
Wataya-Kaneda et al. A monoclonal antibody against the nucleus reveals the presence of a common protein in the nuclear envelope, the perichromosomal region, and cytoplasmic vesicles.
Euhus et al. Detection of a tumor‐associated glycoprotein antigen in serum and urine of melanoma patients by murine monoclonal antibody (AD1‐40F4) in enzyme immunoassay
JP2609858B2 (ja) コラゲナーゼインヒビターの酵素免疫学的定量法
DE3580524D1 (de) Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.
EP0143367A2 (en) Method for production of monoclonal antibodies for cancer diagnosis and therapy
KR910018041A (ko) Pp4에 대한 모노클로날 항체, 이의 제조방법 및 용도
Thorpe et al. Detection and affinity purification of β‐endorphin precursors using a monoclonal antibody
Lin et al. Use of monoclonal antibodies to study cytoskeleton

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment