DK1349855T3 - 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidin-2,4-dionmesylatsalt - Google Patents

5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidin-2,4-dionmesylatsalt

Info

Publication number: DK1349855T3
Authority: DK; Denmark
Prior art keywords: pyridyl; ethoxy; benzyl; amino; methyl
Prior art date: 2000-12-22

Application number

DK01272109T

Other languages

Danish (da)

English (en)

Inventor

Deirdre O'keeffe

Andrew Simon Craig

Tim Chien Ting Ho

Michael Millan

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-22

Filing date

2001-12-21

Publication date

2006-12-27

2000-12-22 Priority claimed from GB0031528A external-priority patent/GB0031528D0/en

2000-12-22 Priority claimed from GB0031524A external-priority patent/GB0031524D0/en

2000-12-22 Priority claimed from GB0031526A external-priority patent/GB0031526D0/en

2000-12-22 Priority claimed from GB0031521A external-priority patent/GB0031521D0/en

2001-12-21 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2006-12-27 Application granted granted Critical

2006-12-27 Publication of DK1349855T3 publication Critical patent/DK1349855T3/da

Links

-1 4- (2- (N-methyl-N- (2-pyridyl) amino) ethoxy) benzyl Chemical group 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
239000003814 drug Substances 0.000 abstract 1
GWLZGWWFCBETCB-UHFFFAOYSA-N methanesulfonic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Chemical class CS(O)(=O)=O.C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O GWLZGWWFCBETCB-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK01272109T 2000-12-22 2001-12-21 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidin-2,4-dionmesylatsalt DK1349855T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0031528A GB0031528D0 (en)	2000-12-22	2000-12-22	Novel pharmaceutical
GB0031524A GB0031524D0 (en)	2000-12-22	2000-12-22	Novel pharmaceutical
GB0031526A GB0031526D0 (en)	2000-12-22	2000-12-22	Novel pharmaceuticals
GB0031521A GB0031521D0 (en)	2000-12-22	2000-12-22	Novel pharmaceutical

Publications (1)

Publication Number	Publication Date
DK1349855T3 true DK1349855T3 (da)	2006-12-27

Family

ID=27447913

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01272109T DK1349855T3 (da)	2000-12-22	2001-12-21	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidin-2,4-dionmesylatsalt

Country Status (12)

Country	Link
US (2)	US20040082620A1 (de)
EP (1)	EP1349855B1 (de)
JP (1)	JP2004520326A (de)
KR (1)	KR100840846B1 (de)
CN (1)	CN1310912C (de)
AT (1)	ATE337313T1 (de)
CY (1)	CY1106226T1 (de)
DE (1)	DE60122580T2 (de)
DK (1)	DK1349855T3 (de)
ES (1)	ES2270955T3 (de)
PT (1)	PT1349855E (de)
WO (1)	WO2002051839A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE39384E1 (en)	1993-09-01	2006-11-07	Smithkline Beecham P.L.C.	Substituted thiazolidinedione derivatives
ES2278977T3 (es) *	2001-11-21	2007-08-16	Smithkline Beecham Plc	Bencenosulfonato de 5-(4-(2-(n-metil-n-(2-piridil)amino)etoxi)bencil)tiazolidin-2,4-diona; procedimiento para su preparacion; polimorfos i, ii y iii de los mismos; y su uso como ingrediente activo farmaceutico.
US20060182692A1 (en) *	2003-12-16	2006-08-17	Fishburn C S	Chemically modified small molecules
HRP20140361T1 (hr) *	2003-12-16	2014-05-23	Nektar Therapeutics	Monodisperzne smjese pegiliranog naloksola
DE102005034406A1 (de) *	2005-07-22	2007-02-01	Ratiopharm Gmbh	Neue Salze von Rosiglitazon
US7435741B2 (en) *	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
EP2062880A1 (de)	2007-11-22	2009-05-27	Bayer Schering Pharma Aktiengesellschaft	5-[(3,3,3-Trifluor-2-hydroxy-1-arylpropyl)amino]-1H-chinolin-2-one, Verfahren zu ihrer Herstellung und ihre Verwendung als entzündungshemmende Wirkstoffe
PE20140636A1 (es)	2010-09-30	2014-06-18	Astrazeneca Ab	Conjugado de naloxol-peg cristalino

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE186724T1 (de) *	1987-09-04	1999-12-15	Beecham Group Plc	Substituierte thiazolidindionderivate
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5741803A (en) *	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives

2001
- 2001-12-21 PT PT01272109T patent/PT1349855E/pt unknown
- 2001-12-21 JP JP2002552934A patent/JP2004520326A/ja active Pending
- 2001-12-21 ES ES01272109T patent/ES2270955T3/es not_active Expired - Lifetime
- 2001-12-21 KR KR1020037008368A patent/KR100840846B1/ko not_active Expired - Fee Related
- 2001-12-21 AT AT01272109T patent/ATE337313T1/de not_active IP Right Cessation
- 2001-12-21 EP EP01272109A patent/EP1349855B1/de not_active Expired - Lifetime
- 2001-12-21 WO PCT/GB2001/005751 patent/WO2002051839A1/en not_active Ceased
- 2001-12-21 CN CNB018227767A patent/CN1310912C/zh not_active Expired - Fee Related
- 2001-12-21 DK DK01272109T patent/DK1349855T3/da active
- 2001-12-21 DE DE60122580T patent/DE60122580T2/de not_active Expired - Fee Related
- 2001-12-21 US US10/451,215 patent/US20040082620A1/en not_active Abandoned
2005
- 2005-08-09 US US11/199,779 patent/US7291740B2/en not_active Expired - Fee Related
2006
- 2006-10-31 CY CY20061101559T patent/CY1106226T1/el unknown

Also Published As

Publication number	Publication date
EP1349855A1 (de)	2003-10-08
KR100840846B1 (ko)	2008-06-23
CN1491224A (zh)	2004-04-21
PT1349855E (pt)	2006-12-29
US20060040993A1 (en)	2006-02-23
JP2004520326A (ja)	2004-07-08
KR20030064855A (ko)	2003-08-02
ES2270955T3 (es)	2007-04-16
US20040082620A1 (en)	2004-04-29
DE60122580T2 (de)	2007-08-30
ATE337313T1 (de)	2006-09-15
US7291740B2 (en)	2007-11-06
EP1349855B1 (de)	2006-08-23
CY1106226T1 (el)	2011-06-08
DE60122580D1 (de)	2006-10-05
WO2002051839A1 (en)	2002-07-04
CN1310912C (zh)	2007-04-18

Publication	Publication Date	Title
DE60112729D1 (de)	2005-09-22	Hcl-salze von 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dion
ATE337313T1 (de)	2006-09-15	5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy)benzyl)thiazolidin-2,4-dion mesylatsalz
DE60212434D1 (de)	2006-07-27	Rosiglitazon-edisylate und ihre verwendung als antidiabetika
AP1715A (en)	2007-02-28	The hydrochloride salt of 5-[ 4 -[2 -(n-methyl-n- (2-pyridyl) amino) ethoxy]benzyl]thiazolidine -2,4-dione
AP1814A (en)	2008-01-04	Tartrate salts of thiazolidinedione derivative.
DE60115062D1 (de)	2005-12-22	Ein thiazolidindionderivat und seine verwendung als antidiabetikum
AP2002002684A0 (en)	2002-12-31	5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2-pyridyl) amino) ethoxy)benzyl) thiazolidine-2,4-dione hydriodide as pharmaceutical
MXPA02012100A (es)	2003-04-25	Sal de tiazodilindiona para el tratamiento de la diabetes mellitus.
DE60124119D1 (de)	2006-12-07	Ein thiazolidindionderivat und seine verwendung als antidiabetikum
AP1785A (en)	2007-10-04	Tartrate salt of thiazolidinedione derivative.
NO20075507L (no)	2003-05-27	Tiazolidindionderivater og deres anvendelse som antidiabetiske midler
DE60217168D1 (de)	2007-02-08	5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dion-benzolsulfonat; prozess zu seiner herstellung; polymorphe i, ii und iii davon; und seine verwendung als pharmazeutischer wirkstoff
SI1265893T1 (sl)	2005-12-31	Hidrokloridne soli 5-(4-(2-(n-metil-n-(2-piridil)amino)etoksi)benzil)tiazolidin-2,4-diona