DK1359979T3 - Anticancer-kombination af substituerede pyrroler og paclitaxel - Google Patents

Anticancer-kombination af substituerede pyrroler og paclitaxel

Info

Publication number: DK1359979T3
Authority: DK; Denmark
Prior art keywords: paclitaxel; anticancer combination; pyrrols; substituted; substituted pyrrols
Prior art date: 2001-02-09

Application number

DK02714140T

Other languages

English (en)

Inventor

Lars Holger Breimer

Kapil Dhingra

Urvashi Hooda Dhingra

Steve Ritland

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-09

Filing date

2002-02-01

Publication date

2006-08-28

2002-02-01 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-08-28 Application granted granted Critical

2006-08-28 Publication of DK1359979T3 publication Critical patent/DK1359979T3/da

Links

229930012538 Paclitaxel Chemical class 0.000 title 1
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical class C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1
239000012635 anticancer drug combination Substances 0.000 title 1
229940046044 combinations of antineoplastic agent Drugs 0.000 title 1
229960001592 paclitaxel Drugs 0.000 title 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical class O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK02714140T 2001-02-09 2002-02-01 Anticancer-kombination af substituerede pyrroler og paclitaxel DK1359979T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US26787401P	2001-02-09	2001-02-09

Publications (1)

Publication Number	Publication Date
DK1359979T3 true DK1359979T3 (da)	2006-08-28

Family

ID=23020488

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02714140T DK1359979T3 (da)	2001-02-09	2002-02-01	Anticancer-kombination af substituerede pyrroler og paclitaxel

Country Status (17)

Country	Link
US (1)	US6548531B2 (da)
EP (1)	EP1359979B1 (da)
JP (1)	JP4128872B2 (da)
KR (1)	KR100542069B1 (da)
CN (1)	CN1265786C (da)
AR (2)	AR035429A1 (da)
AT (1)	ATE324145T1 (da)
AU (1)	AU2002246080B2 (da)
BR (1)	BR0206954A (da)
CA (1)	CA2435921C (da)
DE (1)	DE60210926T2 (da)
DK (1)	DK1359979T3 (da)
ES (1)	ES2261648T3 (da)
MX (1)	MXPA03007036A (da)
PT (1)	PT1359979E (da)
WO (1)	WO2002064214A2 (da)
ZA (1)	ZA200305967B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002072085A1 (en) *	2001-03-14	2002-09-19	Bristol-Myers Squibb Company	Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
JP2004537515A (ja) *	2001-05-15	2004-12-16	フォークファーマシューティカルス，インク．	ウィルス感染症治療用薬物のターゲッティング送達
JP2004532245A (ja) *	2001-05-15	2004-10-21	ページダブルフォーク	癌を治療するための生体影響性化合物の標的送達
WO2002102373A1 (en) *	2001-06-15	2002-12-27	F. Hoffmann-La Roche Ag	Method for administration of cancer therapeutic
US20030139373A1 (en) *	2001-11-20	2003-07-24	Breimer Lars Holger	Method for cancer therapy
SI1853250T1 (sl)	2005-02-18	2012-01-31	Abraxis Bioscience Llc	Kombinacije in reĹľimi dajanja terapevtskih sredstev in kombinirana terapija
US8735394B2 (en) *	2005-02-18	2014-05-27	Abraxis Bioscience, Llc	Combinations and modes of administration of therapeutic agents and combination therapy
KR20130028727A (ko)	2010-03-29	2013-03-19	아브락시스 바이오사이언스, 엘엘씨	치료제의 약물 전달 및 유효성 향상 방법
NZ717490A (en)	2010-03-29	2017-12-22	Abraxis Bioscience Llc	Methods of treating cancer
BR112012030909A2 (pt)	2010-06-04	2020-08-18	Abraxis Bioscience, Llc	métodos de tratamento de câncer pancreático
TW201613576A (en)	2014-06-26	2016-04-16	Novartis Ag	Intermittent dosing of MDM2 inhibitor
MX388093B (es)	2016-11-15	2025-03-19	Novartis Ag	Dosis y regimen para inhibidores de la interaccion hdm2-p53.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ280738B6 (cs)	1988-02-10	1996-04-17	F. Hoffmann - La Roche And Co., Aktiengesellschaft	Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
US6080777A (en) *	1992-01-31	2000-06-27	The Trustees Of Columbia University In The City Of New York	Taxol as a radiation sensitizer
CA2086874E (en)	1992-08-03	2000-01-04	Renzo Mauro Canetta	Methods for administration of taxol
WO1994004541A2 (en) *	1992-08-12	1994-03-03	The Upjohn Company	Protein kinase inhibitors and related compounds combined with taxol
ES2203111T3 (es)	1998-03-17	2004-04-01	F. Hoffmann-La Roche Ag	Maleimidas bisindol sustituidas para la inhibicion de proloferacion celular.
JP2002512954A (ja) *	1998-04-24	2002-05-08	マイトコー	ミトコンドリア関連疾患を処置するための化合物および方法
US6277844B1 (en) *	1998-09-14	2001-08-21	Sydney Spector	Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
US6350786B1 (en)	1998-09-22	2002-02-26	Hoffmann-La Roche Inc.	Stable complexes of poorly soluble compounds in ionic polymers
US6335194B1 (en) *	1998-09-29	2002-01-01	Isis Pharmaceuticals, Inc.	Antisense modulation of survivin expression

2002
- 2002-01-23 US US10/055,451 patent/US6548531B2/en not_active Expired - Lifetime
- 2002-02-01 WO PCT/EP2002/001042 patent/WO2002064214A2/en not_active Ceased
- 2002-02-01 ES ES02714140T patent/ES2261648T3/es not_active Expired - Lifetime
- 2002-02-01 AT AT02714140T patent/ATE324145T1/de active
- 2002-02-01 MX MXPA03007036A patent/MXPA03007036A/es active IP Right Grant
- 2002-02-01 CA CA002435921A patent/CA2435921C/en not_active Expired - Lifetime
- 2002-02-01 JP JP2002564006A patent/JP4128872B2/ja not_active Expired - Lifetime
- 2002-02-01 AU AU2002246080A patent/AU2002246080B2/en not_active Expired
- 2002-02-01 BR BR0206954-7A patent/BR0206954A/pt not_active Application Discontinuation
- 2002-02-01 EP EP02714140A patent/EP1359979B1/en not_active Expired - Lifetime
- 2002-02-01 CN CNB028047516A patent/CN1265786C/zh not_active Expired - Lifetime
- 2002-02-01 DE DE60210926T patent/DE60210926T2/de not_active Expired - Lifetime
- 2002-02-01 PT PT02714140T patent/PT1359979E/pt unknown
- 2002-02-01 KR KR1020037010445A patent/KR100542069B1/ko not_active Expired - Lifetime
- 2002-02-01 DK DK02714140T patent/DK1359979T3/da active
- 2002-02-07 AR ARP020100400A patent/AR035429A1/es not_active Application Discontinuation
2003
- 2003-08-01 ZA ZA2003/05967A patent/ZA200305967B/en unknown
2014
- 2014-12-12 AR ARP140104645A patent/AR098745A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20040025894A (ko)	2004-03-26
EP1359979A2 (en)	2003-11-12
AR035429A1 (es)	2004-05-26
ES2261648T3 (es)	2006-11-16
DE60210926D1 (de)	2006-06-01
JP4128872B2 (ja)	2008-07-30
WO2002064214A3 (en)	2003-05-30
CA2435921C (en)	2009-12-22
CN1265786C (zh)	2006-07-26
AR098745A2 (es)	2016-06-08
BR0206954A (pt)	2004-02-25
CN1491126A (zh)	2004-04-21
US6548531B2 (en)	2003-04-15
AU2002246080B2 (en)	2006-08-10
MXPA03007036A (es)	2003-11-18
JP2004517961A (ja)	2004-06-17
EP1359979B1 (en)	2006-04-26
PT1359979E (pt)	2006-08-31
WO2002064214A8 (en)	2004-02-19
DE60210926T2 (de)	2007-01-11
US20020156118A1 (en)	2002-10-24
CA2435921A1 (en)	2002-08-22
WO2002064214A2 (en)	2002-08-22
AU2002246080C1 (en)	2002-08-28
ZA200305967B (en)	2005-01-26
ATE324145T1 (de)	2006-05-15
KR100542069B1 (ko)	2006-01-11

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DE50209252D1 (de)	2007-02-22	Distraktionsvorrichtung
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DE60212600D1 (de)	2006-08-03	Audiocodierung und decodierung
DK1438306T3 (da)	2014-06-23	Derivater af UK-2A
EP1455387A4 (en)	2005-02-02	Probe device
EP1412378A4 (en)	2006-09-20	APTAMERS AND ANTIAPTAMERS
IS7089A (is)	2003-12-22	Lyfjasamsetningar amlódipíns og atórvastatíns
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NO20033737D0 (no)	2003-08-22	PEG-konjugater av IIGT-NK4
DK1359979T3 (da)	2006-08-28	Anticancer-kombination af substituerede pyrroler og paclitaxel
DE60217266D1 (de)	2007-02-15	Spannband
EP1457474A4 (en)	2006-08-09	EXPLOSIVE
DE50202252D1 (de)	2005-03-17	Wandlerschaltung
DE60126734D1 (de)	2007-04-05	Superiostealer Knochenanker
DE60226922D1 (de)	2008-07-17	Elektronisches Uhrwerk
DK1372652T3 (da)	2008-09-22	Kombination af docetaxel og flavopiridol
EP1468113A4 (en)	2006-09-06	OPTINEURINE AND GLAUCOMA
ATE299873T1 (de)	2005-08-15	Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate
DK1385513T3 (da)	2007-01-15	Farmaceutiske kombinationer af pyridoindollonderivater og anticancermidler
NO20016399D0 (no)	2001-12-27	Mini-kraftomformer II
DE60222443D1 (de)	2007-10-25	Vorverstärkungsschaltung
NO20042126L (no)	2004-06-23	Syntese av 2-aralkoksyadenosiner og 2-alkoksyadenosiner
DE50214325D1 (de)	2010-05-20	Einblatt-Überkopf-Tor
DE60230658D1 (de)	2009-02-12	Stigkeit