DK1373502T3 - Dopaminerge neuronale overlevelsesfremmende faktorer og avendelser heraf - Google Patents
Dopaminerge neuronale overlevelsesfremmende faktorer og avendelser herafInfo
- Publication number
- DK1373502T3 DK1373502T3 DK02706572.1T DK02706572T DK1373502T3 DK 1373502 T3 DK1373502 T3 DK 1373502T3 DK 02706572 T DK02706572 T DK 02706572T DK 1373502 T3 DK1373502 T3 DK 1373502T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- manf
- neuronal survival
- dopaminergic neuronal
- causes
- Prior art date
Links
- 230000003291 dopaminomimetic effect Effects 0.000 title abstract 2
- 230000006576 neuronal survival Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- AVVWPBAENSWJCB-GASJEMHNSA-N D-mannofuranose Chemical compound OC[C@@H](O)[C@H]1OC(O)[C@@H](O)[C@H]1O AVVWPBAENSWJCB-GASJEMHNSA-N 0.000 abstract 3
- 101000616876 Homo sapiens Mesencephalic astrocyte-derived neurotrophic factor Proteins 0.000 abstract 3
- 102100021833 Mesencephalic astrocyte-derived neurotrophic factor Human genes 0.000 abstract 3
- 238000002054 transplantation Methods 0.000 abstract 2
- 230000004071 biological effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27751601P | 2001-03-20 | 2001-03-20 | |
| PCT/CA2002/000373 WO2002074956A2 (en) | 2001-03-20 | 2002-03-20 | Dopaminergic neuronal survival-promoting factors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1373502T3 true DK1373502T3 (da) | 2011-01-10 |
Family
ID=23061211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02706572.1T DK1373502T3 (da) | 2001-03-20 | 2002-03-20 | Dopaminerge neuronale overlevelsesfremmende faktorer og avendelser heraf |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20020182198A1 (da) |
| EP (1) | EP1373502B8 (da) |
| JP (1) | JP2004528835A (da) |
| AT (1) | ATE485377T1 (da) |
| CA (1) | CA2441740A1 (da) |
| DE (1) | DE60238038D1 (da) |
| DK (1) | DK1373502T3 (da) |
| ES (1) | ES2353490T3 (da) |
| WO (1) | WO2002074956A2 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60238038D1 (de) | 2001-03-20 | 2010-12-02 | Cns Protein Therapeutics Inc | Das Überleben dopaminerger Neuronen fördernde Faktoren und deren Verwendungen |
| US7452969B2 (en) * | 2002-08-30 | 2008-11-18 | Licentia Ltd | Neurotrophic factor protein and uses thereof |
| EP1644406B1 (en) | 2003-07-11 | 2012-08-15 | DeveloGen Aktiengesellschaft | Use of dg153 secreted protein products for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome |
| PL1969003T3 (pl) * | 2005-12-14 | 2011-05-31 | Herantis Pharma Plc | Zastosowanie białka czynnika neurotroficznego |
| WO2009120810A2 (en) * | 2008-03-25 | 2009-10-01 | Cns Protein Therapeutics, Inc. | Neurodegenerative disorders |
| FI20080326A0 (fi) | 2008-04-30 | 2008-04-30 | Licentia Oy | Neurotroofinen tekijä MANF ja sen käytöt |
| WO2011038366A1 (en) * | 2009-09-25 | 2011-03-31 | Amarantus Therapeutics, Inc. | Dopaminergic selective factors |
| CA2838818A1 (en) * | 2011-06-09 | 2012-12-13 | University Of Miami | Methods of treatment for retinal diseases |
| FI20115870A0 (fi) * | 2011-09-05 | 2011-09-05 | Urmas Arumaee | Neuroprotektiiviset soluihin tunkeutuvat peptidit |
| EP2820424B1 (en) * | 2012-01-24 | 2016-12-07 | University of Massachusetts | Soluble manf in pancreatic beta-cell disorders |
| EP3122370A1 (en) * | 2014-03-28 | 2017-02-01 | Buck Institute for Research on Aging | Methods and compositions for modulating the immune system |
| US20190192629A1 (en) * | 2015-11-18 | 2019-06-27 | Herantis Pharma Plc | Compositions Comprising CDNF or MANF for use in the Intranasal Treatment of Central Nervous System Diseases |
| EP3774858B1 (en) * | 2018-03-29 | 2025-07-30 | MyNeuroCure Oy | C-terminal cdnf fragments having neuroprotective effect |
| CN113292656B (zh) * | 2020-02-21 | 2022-10-25 | 四川大学华西医院 | 用于防治肥胖的中脑星形胶质细胞源性神经营养因子的融合蛋白 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001019851A2 (en) * | 1999-09-16 | 2001-03-22 | Neurotrophic Bioscience Inc. | Opaminergic neuronal survival-promoting factors and uses thereof |
| EP1225224A4 (en) * | 1999-10-01 | 2004-03-24 | Kyowa Hakko Kogyo Kk | DNA THE SHEAR RESPONSE |
| AU2001250912B2 (en) * | 2000-03-21 | 2007-01-04 | Curagen Corporation | VEGF-modulated genes and methods employing them |
| DE60238038D1 (de) | 2001-03-20 | 2010-12-02 | Cns Protein Therapeutics Inc | Das Überleben dopaminerger Neuronen fördernde Faktoren und deren Verwendungen |
| EP1373314A2 (en) * | 2001-03-30 | 2004-01-02 | Geneprot, Inc. | Human arginine-rich protein-related compositions |
| WO2002090541A1 (en) * | 2001-05-03 | 2002-11-14 | Murdoch Childrens Research Institute | Determination of a genetic predisposition for behavioural disorders |
| GB0113657D0 (en) * | 2001-06-05 | 2001-07-25 | Geneprot Inc | Improved native chemical ligation with three or more components |
| US7452969B2 (en) | 2002-08-30 | 2008-11-18 | Licentia Ltd | Neurotrophic factor protein and uses thereof |
| US20060195915A1 (en) | 2002-08-30 | 2006-08-31 | Licentia Ltd. | Novel neurotrophic factor protein and uses thereof |
| WO2009120810A2 (en) | 2008-03-25 | 2009-10-01 | Cns Protein Therapeutics, Inc. | Neurodegenerative disorders |
| FI20080326A0 (fi) | 2008-04-30 | 2008-04-30 | Licentia Oy | Neurotroofinen tekijä MANF ja sen käytöt |
| CA2838818A1 (en) | 2011-06-09 | 2012-12-13 | University Of Miami | Methods of treatment for retinal diseases |
-
2002
- 2002-03-20 DE DE60238038T patent/DE60238038D1/de not_active Expired - Lifetime
- 2002-03-20 US US10/102,265 patent/US20020182198A1/en not_active Abandoned
- 2002-03-20 CA CA002441740A patent/CA2441740A1/en not_active Abandoned
- 2002-03-20 WO PCT/CA2002/000373 patent/WO2002074956A2/en not_active Ceased
- 2002-03-20 JP JP2002574347A patent/JP2004528835A/ja active Pending
- 2002-03-20 DK DK02706572.1T patent/DK1373502T3/da active
- 2002-03-20 AT AT02706572T patent/ATE485377T1/de not_active IP Right Cessation
- 2002-03-20 ES ES02706572T patent/ES2353490T3/es not_active Expired - Lifetime
- 2002-03-20 EP EP02706572A patent/EP1373502B8/en not_active Expired - Lifetime
-
2009
- 2009-08-04 US US12/535,029 patent/US8084425B2/en not_active Expired - Fee Related
-
2011
- 2011-11-28 US US13/305,025 patent/US9115208B2/en not_active Expired - Fee Related
-
2015
- 2015-06-30 US US14/755,272 patent/US20160152673A1/en not_active Abandoned
-
2017
- 2017-02-27 US US15/443,712 patent/US20170298110A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100119491A1 (en) | 2010-05-13 |
| US9115208B2 (en) | 2015-08-25 |
| EP1373502B1 (en) | 2010-10-20 |
| US20020182198A1 (en) | 2002-12-05 |
| ES2353490T3 (es) | 2011-03-02 |
| WO2002074956A3 (en) | 2003-07-10 |
| CA2441740A1 (en) | 2002-09-26 |
| US8084425B2 (en) | 2011-12-27 |
| US20170298110A1 (en) | 2017-10-19 |
| EP1373502A2 (en) | 2004-01-02 |
| EP1373502B8 (en) | 2010-12-22 |
| DE60238038D1 (de) | 2010-12-02 |
| JP2004528835A (ja) | 2004-09-24 |
| ATE485377T1 (de) | 2010-11-15 |
| US20130078220A1 (en) | 2013-03-28 |
| WO2002074956A2 (en) | 2002-09-26 |
| US20160152673A1 (en) | 2016-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0412845A (pt) | herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo | |
| ATE485377T1 (de) | Das überleben dopaminerger neuronen fördernde faktoren und deren verwendungen | |
| ES2170104T3 (es) | Inhibidores de la produccion de proteinas de beta-amiloide. | |
| DE602004020263D1 (de) | Amino-substituierte diaryläa,dücyclohepten- analoga als muscarinische agonisten und verfahren zur behandlung von neuropsychiatrischen erkrankungen | |
| BRPI0015533B8 (pt) | enzima alfa-l-iduronidase humana recombinante, composição farmacêutica compreendendo a mesma e método para sua purificação | |
| BRPI0407662B8 (pt) | derivados do ácido 1-fenilalcanocarboxílico para o tratamento de doenças neurodegenerativas | |
| ATE490786T1 (de) | Behandlung von verletzungen des zentralen nervensystems | |
| ATE229806T1 (de) | Wirkstoff zur behandlung neurodegenerativer störungen | |
| IL136690A0 (en) | Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas | |
| NO20004803L (no) | Smilagening og anzurogenin for behandling av Alzheimers sykdom | |
| DE60216830D1 (de) | Pharmazeutische Zusammensetzungen zur Behandlung von Störungen des ZNS oder anderen Erkrankungen | |
| EA200401365A1 (ru) | Способы лечения илеуса | |
| ATE300052T1 (de) | Verwendung von radioliganden zum screening von inhibitoren der herstellung von beta-amyloid peptiden | |
| NO20092741L (no) | DR6-antagonister og anvendelse derav ved behandling av neurologiske forstyrrelser | |
| ATE311476T1 (de) | Polymorphismen im gen für den humanen organischen anionentransporter c (oatp-c) | |
| WO2001019851A3 (en) | Opaminergic neuronal survival-promoting factors and uses thereof | |
| ATE348158T1 (de) | Neuartiges collectin | |
| PT1255734E (pt) | Derivados de isatina com actividade neurotrofica | |
| ATE548048T1 (de) | Oncomodulin zur behandlung von neurologishen erkrankungen | |
| BR0314541A (pt) | Tratamento de demência e doença de parkinson | |
| ATE391915T1 (de) | Verwendung des proteins grf-1 zur auswahl von molekülen | |
| DE60004093D1 (de) | Pharmazeutische zusammensetzung welche riluzol und gabapentin enthält zur behandung von motoneuronalen krankheiten | |
| SE9902489D0 (sv) | Mutated Nurr1 gene | |
| DE60224778D1 (de) | Zusammensetzungen und Verfahren zur Behandlung und zur Detektion von proliferativen Störungen die mit der Überexpression des menschlichen "Transketolase like-1" gens in Zusammenhang stehen | |
| ATE397753T1 (de) | Screening-verfahren für eine prophylaktische und therapeutische substanz für eine nierenerkrankung |