DK1384717T3 - 2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister - Google Patents

2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister

Info

Publication number
DK1384717T3
DK1384717T3 DK03018662T DK03018662T DK1384717T3 DK 1384717 T3 DK1384717 T3 DK 1384717T3 DK 03018662 T DK03018662 T DK 03018662T DK 03018662 T DK03018662 T DK 03018662T DK 1384717 T3 DK1384717 T3 DK 1384717T3
Authority
DK
Denmark
Prior art keywords
triphenylmethyl
tetrazol
intermediates
synthesis
receptor antagonists
Prior art date
Application number
DK03018662T
Other languages
English (en)
Inventor
Young Sek Lo
Lucius Thomas Rossano
Robert D Larsen
Anthony O King
Original Assignee
Du Pont
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/793,514 external-priority patent/US5130439A/en
Priority claimed from US07/911,812 external-priority patent/US5310928A/en
Application filed by Du Pont, Merck & Co Inc filed Critical Du Pont
Priority claimed from PCT/US1992/009979 external-priority patent/WO1993010106A1/en
Application granted granted Critical
Publication of DK1384717T3 publication Critical patent/DK1384717T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/05—Cyclic compounds having at least one ring containing boron but no carbon in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK03018662T 1991-11-18 1992-11-18 2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister DK1384717T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/793,514 US5130439A (en) 1991-11-18 1991-11-18 Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists
US07/911,813 US5206374A (en) 1991-11-18 1992-07-10 Process for preparing tetrazolylphenylboronic acid intermediates
US07/911,812 US5310928A (en) 1991-11-18 1992-07-10 Process for preparing biphenyltetrazole compounds
PCT/US1992/009979 WO1993010106A1 (en) 1991-11-18 1992-11-18 Tetrazolylphenylboronic acid intermediates for the synthesis of aii receptor antagonists

Publications (1)

Publication Number Publication Date
DK1384717T3 true DK1384717T3 (da) 2008-09-08

Family

ID=27121398

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03018662T DK1384717T3 (da) 1991-11-18 1992-11-18 2-(2'Triphenylmethyl-2'H-tetrazol-5'-yl)phenylboronsyre som mellemprodukter til syntese af AII receptorantagonister

Country Status (3)

Country Link
US (1) US5206374A (da)
DK (1) DK1384717T3 (da)
ES (1) ES2306829T3 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4319041A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Trisubstituierte Biphenyle
AU685898B2 (en) * 1993-12-23 1998-01-29 Du Pont Merck Pharmaceutical Company, The Polymorphs of losartan and the process for the preparation of form II of losartan
PT937068E (pt) * 1996-10-29 2002-07-31 Merck & Co Inc Processo para a cristalizacao de losartan
HU222773B1 (hu) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás egy ismert tetrazolszármazék előállítására
CA2672549A1 (en) * 2001-11-14 2003-06-12 Ben-Zion Dolitzky Amorphous and crystalline forms of losartan potassium and process for their preparation
DE60304175T2 (de) * 2002-04-29 2007-03-15 Teva Pharmaceutical Industries Ltd. Verfahren zur herstellung von losartan und losartan-kaliumsalz
GB0402262D0 (en) * 2004-02-02 2004-03-10 Novartis Ag Process for the manufacture of organic compounds
US20070026026A1 (en) * 2005-08-01 2007-02-01 David Delmarre Oral liquid losartan compositions
EP2081892A4 (en) 2006-11-17 2014-03-05 Donald F Weaver COMPOUNDS AND METHOD FOR THE TREATMENT OF PROTEIN DISAPPEARANCE
CN101475564B (zh) * 2009-01-22 2012-05-23 江苏德峰药业有限公司 一种氯沙坦钾的制备方法
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
CN108047208B (zh) * 2018-01-12 2022-03-22 浙江华海药业股份有限公司 一种降低氯沙坦二聚物杂质的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH530980A (de) * 1969-03-05 1972-11-30 Sandoz Ag Verfahren zur Herstellung von Imidazo(2,1-a)isoindolen
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
GB9017480D0 (en) * 1990-08-09 1990-09-26 Ici Plc Chemical process
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process

Also Published As

Publication number Publication date
ES2306829T3 (es) 2008-11-16
US5206374A (en) 1993-04-27

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