DK13888A - Krystallinsk cefadroxil, fremgangsmaade til dets fremstilling, og farmaceutisk praeparat indeholdende et saadant - Google Patents

Krystallinsk cefadroxil, fremgangsmaade til dets fremstilling, og farmaceutisk praeparat indeholdende et saadant

Info

Publication number: DK13888A
Authority: DK; Denmark
Prior art keywords: cefadroxil; preparation; crystallinic; procedure; cefadroxyl
Prior art date: 1987-04-24

Application number

DK013888A

Other languages

Danish (da)

English (en)

Other versions

DK13888D0 (da

Inventor

Leonardo Marsili

Original Assignee

Rifar Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-24

Filing date

1988-01-13

Publication date

1988-10-25

1987-04-24 Priority claimed from GB878709804A external-priority patent/GB8709804D0/en

1987-08-04 Priority claimed from GB878718394A external-priority patent/GB8718394D0/en

1988-01-13 Application filed by Rifar Srl filed Critical Rifar Srl

1988-01-13 Publication of DK13888D0 publication Critical patent/DK13888D0/da

1988-10-25 Publication of DK13888A publication Critical patent/DK13888A/da

Links

229960004841 cefadroxil Drugs 0.000 title abstract 2
NBFNMSULHIODTC-CYJZLJNKSA-N cefadroxil monohydrate Chemical compound O.C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=C(O)C=C1 NBFNMSULHIODTC-CYJZLJNKSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 abstract 2
ATHHXGZTWNVVOU-UHFFFAOYSA-N N-methylformamide Chemical compound CNC=O ATHHXGZTWNVVOU-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
KFZMGEQAYNKOFK-UHFFFAOYSA-N isopropyl alcohol Natural products CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
239000012453 solvate Substances 0.000 abstract 2
FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
238000001914 filtration Methods 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

DK013888A 1987-04-24 1988-01-13 Krystallinsk cefadroxil, fremgangsmaade til dets fremstilling, og farmaceutisk praeparat indeholdende et saadant DK13888A (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB878709804A GB8709804D0 (en)	1987-04-24	1987-04-24	Crystalline cefadroxil
GB878718394A GB8718394D0 (en)	1987-08-04	1987-08-04	Crystalline cefadroxil hemihydrate
US07/089,168 US4904776A (en)	1987-04-24	1987-08-25	Method for producing crystalline cefadroxil hemihydrate

Publications (2)

Publication Number	Publication Date
DK13888D0 DK13888D0 (da)	1988-01-13
DK13888A true DK13888A (da)	1988-10-25

Family

ID=27263404

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK013888A DK13888A (da)	1987-04-24	1988-01-13	Krystallinsk cefadroxil, fremgangsmaade til dets fremstilling, og farmaceutisk praeparat indeholdende et saadant

Country Status (13)

Country	Link
US (1)	US4904776A (fr)
EP (1)	EP0287751B1 (fr)
JP (1)	JP2620582B2 (fr)
CN (1)	CN1019804B (fr)
AT (1)	ATE116322T1 (fr)
AU (1)	AU595415B2 (fr)
DE (1)	DE3852560T2 (fr)
DK (1)	DK13888A (fr)
ES (1)	ES2068812T3 (fr)
FI (1)	FI87569C (fr)
PH (1)	PH26292A (fr)
PT (1)	PT86653B (fr)
SU (1)	SU1630613A3 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8714180D0 (en) *	1987-06-17	1987-07-22	Rifar Srl	Anhydrous crystalline cefadroxil
JPH089630B2 (ja) *	1989-07-10	1996-01-31	ヘマ・ソシエダード・アノニマ	有機化合物の、または関連する改善
IN190389B (fr)	1999-07-14	2003-07-26	Ranbaxy Lab Ltd
WO2001004126A1 (fr) *	1999-07-14	2001-01-18	Ranbaxy Laboratories Limited	Procede de preparation de semi-hydrate cefadroxil cristallin a partir d'un produit de solvatation cefadroxil dimethyl formamide
CN1311830C (zh) *	2004-02-27	2007-04-25	石药集团中奇制药技术（石家庄）有限公司	头孢羟氨苄口腔崩解片及其制备方法
KR101420451B1 (ko) *	2006-05-19	2014-07-16	디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이.	세파드록실의 결정화 방법
CN102134250B (zh) *	2011-01-19	2013-03-13	天津大学	一种头孢羟氨苄单水合物的结晶方法及结晶
CN104447795B (zh) *	2014-11-28	2016-08-17	珠海金鸿药业股份有限公司	一种头孢羟氨苄化合物及其药物组合物
CN105534937B (zh) *	2015-12-30	2019-12-03	石药集团欧意药业有限公司	一种头孢羟氨苄片剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1532682A (en) *	1976-04-27	1978-11-22	Bristol Myers Co	Process for the preparation of cephadroxil
US4504697A (en) *	1982-04-28	1985-03-12	Littelfuse, Inc.	Sealed electrical devices

1987
- 1987-08-25 US US07/089,168 patent/US4904776A/en not_active Expired - Fee Related
1988
- 1988-01-13 DK DK013888A patent/DK13888A/da not_active Application Discontinuation
- 1988-01-14 AU AU10285/88A patent/AU595415B2/en not_active Ceased
- 1988-01-14 EP EP88100478A patent/EP0287751B1/fr not_active Expired - Lifetime
- 1988-01-14 AT AT88100478T patent/ATE116322T1/de not_active IP Right Cessation
- 1988-01-14 DE DE3852560T patent/DE3852560T2/de not_active Expired - Fee Related
- 1988-01-14 ES ES88100478T patent/ES2068812T3/es not_active Expired - Lifetime
- 1988-01-28 PT PT86653A patent/PT86653B/pt not_active IP Right Cessation
- 1988-02-02 JP JP63022670A patent/JP2620582B2/ja not_active Expired - Lifetime
- 1988-02-15 SU SU884355195A patent/SU1630613A3/ru active
- 1988-03-07 FI FI881038A patent/FI87569C/fi not_active IP Right Cessation
- 1988-04-04 PH PH36729A patent/PH26292A/en unknown
- 1988-04-06 CN CN88101895A patent/CN1019804B/zh not_active Expired

Also Published As

Publication number	Publication date
EP0287751A3 (en)	1990-05-02
FI87569C (fi)	1993-01-25
EP0287751B1 (fr)	1994-12-28
DK13888D0 (da)	1988-01-13
PT86653A (pt)	1988-02-01
JP2620582B2 (ja)	1997-06-18
FI881038A0 (fi)	1988-03-07
ATE116322T1 (de)	1995-01-15
DE3852560D1 (de)	1995-02-09
CN88101895A (zh)	1988-11-30
AU595415B2 (en)	1990-03-29
SU1630613A3 (ru)	1991-02-23
PT86653B (pt)	1992-07-31
FI87569B (fi)	1992-10-15
EP0287751A2 (fr)	1988-10-26
ES2068812T3 (es)	1995-05-01
PH26292A (en)	1992-04-10
FI881038L (fi)	1988-10-25
AU1028588A (en)	1988-10-27
DE3852560T2 (de)	1995-05-04
JPS63267789A (ja)	1988-11-04
CN1019804B (zh)	1992-12-30
US4904776A (en)	1990-02-27

Legal Events

Date	Code	Title	Description
1998-12-07	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK513385A (da)	1986-05-10	Polypeptid, fremgangsmaade til dets fremstilling og farmaceutisk praeparat indeholdende et saadant polypeptid
DK13888D0 (da)	1988-01-13	Krystallinsk cefadroxil, fremgangsmaade til dets fremstilling, og farmaceutisk praeparat indeholdende et saadant
ES8705411A1 (es)	1987-05-01	Procedimiento para preparar derivados de 1-piperazinacarboxamida
NO168425C (no)	1992-02-19	Fremgangsmaate ved fremstilling av krystallinsk cefadroksilmonohydrat
DK680487A (da)	1988-12-18	I det vaesentlige vandfrit, krystallinsk cefadroxil og fremgangsmaade til fremstilling deraf
JPS567799A (en)	1981-01-27	Novel pseudotrisaccharide* its manufacture and use as medicine
DE3470312D1 (de)	1988-05-11	Ether of n-propanolamine derivative
ATE75479T1 (de)	1992-05-15	N-acetyl-3-fluorneuraminsaeurederivate und deren herstellung.
JPS5663953A (en)	1981-05-30	Novel preparation of n- 1-ethyl-2-pyrrolidinylmethyl -2- methoxy-5-sulfamoylbenzamide
FI911961A0 (fi)	1991-04-23	Analoger av tillvaexthormon frigoerande faktorer.
JPS55147246A (en)	1980-11-17	Preparation of alpha-chloro-beta-alanine