DK1398046T3 - Antibiotikum-/antibiotika-polymer-komposit - Google Patents

Antibiotikum-/antibiotika-polymer-komposit

Info

Publication number: DK1398046T3
Authority: DK; Denmark
Prior art keywords: antibiotic; iii; water; salt; composite
Prior art date: 2002-09-11

Application number

DK03019738T

Other languages

Danish (da)

English (en)

Inventor

Sebastian Dr Vogt

Matthias Dr Schnabelrauch

Klaus-Dieter Dr Kuehn

Original Assignee

Heraeus Kulzer Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-11

Filing date

2003-08-29

Publication date

2005-10-10

2003-08-29 Application filed by Heraeus Kulzer Gmbh filed Critical Heraeus Kulzer Gmbh

2005-10-10 Application granted granted Critical

2005-10-10 Publication of DK1398046T3 publication Critical patent/DK1398046T3/da

Links

230000003115 biocidal effect Effects 0.000 title abstract 4
239000002131 composite material Substances 0.000 title abstract 3
229920000642 polymer Polymers 0.000 title abstract 3
150000003839 salts Chemical class 0.000 abstract 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
239000004721 Polyphenylene oxide Substances 0.000 abstract 2
239000004098 Tetracycline Substances 0.000 abstract 2
229940126575 aminoglycoside Drugs 0.000 abstract 2
239000008240 homogeneous mixture Substances 0.000 abstract 2
230000002209 hydrophobic effect Effects 0.000 abstract 2
-1 poly(vinyl fluoride) Polymers 0.000 abstract 2
229920000570 polyether Polymers 0.000 abstract 2
229960002180 tetracycline Drugs 0.000 abstract 2
229930101283 tetracycline Natural products 0.000 abstract 2
235000019364 tetracycline Nutrition 0.000 abstract 2
150000003522 tetracyclines Chemical class 0.000 abstract 2
DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 abstract 1
OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 abstract 1
GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 abstract 1
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
102000002068 Glycopeptides Human genes 0.000 abstract 1
108010015899 Glycopeptides Proteins 0.000 abstract 1
KYGZCKSPAKDVKC-UHFFFAOYSA-N Oxolinic acid Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC2=C1OCO2 KYGZCKSPAKDVKC-UHFFFAOYSA-N 0.000 abstract 1
BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229960003260 chlorhexidine Drugs 0.000 abstract 1
229920001577 copolymer Polymers 0.000 abstract 1
239000000178 monomer Substances 0.000 abstract 1
239000003910 polypeptide antibiotic agent Substances 0.000 abstract 1
229920002620 polyvinyl fluoride Polymers 0.000 abstract 1
229920000131 polyvinylidene Polymers 0.000 abstract 1
239000003306 quinoline derived antiinfective agent Substances 0.000 abstract 1
150000003952 β-lactams Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Surgery (AREA)
Vascular Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Materials For Medical Uses (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compositions Of Macromolecular Compounds (AREA)

DK03019738T 2002-09-11 2003-08-29 Antibiotikum-/antibiotika-polymer-komposit DK1398046T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10242476A DE10242476B4 (de)	2002-09-11	2002-09-11	Antibiotikum-/Antibiotika-Polymer-Kombination

Publications (1)

Publication Number	Publication Date
DK1398046T3 true DK1398046T3 (da)	2005-10-10

Family

ID=31724720

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03019738T DK1398046T3 (da)	2002-09-11	2003-08-29	Antibiotikum-/antibiotika-polymer-komposit

Country Status (13)

Country	Link
US (1)	US20040137065A1 (fr)
EP (1)	EP1398046B1 (fr)
JP (1)	JP4528507B2 (fr)
CN (1)	CN1494925A (fr)
AT (1)	ATE300319T1 (fr)
AU (1)	AU2003244544B2 (fr)
BR (1)	BR0303493A (fr)
CA (1)	CA2438346C (fr)
DE (2)	DE10242476B4 (fr)
DK (1)	DK1398046T3 (fr)
ES (1)	ES2242920T3 (fr)
PT (1)	PT1398046E (fr)
ZA (1)	ZA200307059B (fr)

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US7279174B2 (en) *	2003-05-08	2007-10-09	Advanced Cardiovascular Systems, Inc.	Stent coatings comprising hydrophilic additives
EP2594259A1 (fr)	2004-08-04	2013-05-22	Brookwood Pharmaceuticals, Inc.	Procédé de production de systèmes d'administration, et systèmes d'administration
US20070197548A1 (en) *	2006-02-17	2007-08-23	Murthy Yerramilli V S	Fluoroquinolone compositions
US20070196398A1 (en) *	2006-02-17	2007-08-23	Murthy Yerramilli V S	Fluoroquinolone fatty acid salt compositions
DE102006033312A1 (de) *	2006-07-17	2008-01-31	Heraeus Kulzer Gmbh	Dentales Implantatsystemteil mit einer Beschichtung
CA2709712C (fr)	2007-12-20	2016-05-10	Surmodics Pharmaceuticals, Inc.	Procede pour preparer des microparticules ayant un faible volume de solvant residuel
WO2009124386A1 (fr) *	2008-04-07	2009-10-15	Interface Biologics Inc.	Polythérapie pour le traitement des infections bactériennes
US20100069854A1 (en) *	2008-09-12	2010-03-18	Onajite Okoh	Elastomeric Devices Containing Chlorhexidine/Fatty Acid Salts Made From Fatty Acids of 12 to 18 Carbons
US9763697B2 (en)	2008-12-16	2017-09-19	DePuy Synthes Products, Inc.	Anti-infective spinal rod with surface features
US10314935B2 (en)	2009-01-07	2019-06-11	Entrotech Life Sciences, Inc.	Chlorhexidine-containing antimicrobial laminates
US8545459B2 (en) *	2009-02-25	2013-10-01	Teleflex Medical Incorporated	Stabilized enzyme compositions
US9333280B2 (en)	2009-02-25	2016-05-10	Teleflex Medical Incorporated	Stabilized enzyme compositions
US20100234815A1 (en) *	2009-03-11	2010-09-16	Teleflex Medical Incorporated	Stable melt processable chlorhexidine compositions
DE102010020940B4 (de) *	2010-05-19	2014-09-25	Heraeus Medical Gmbh	Antibiotische Beschichtung
US8834772B2 (en)	2011-12-07	2014-09-16	Biomet Manufacturing, Llc	Antimicrobial methacrylate cements
US9386772B2 (en) *	2012-02-14	2016-07-12	Allegiance Corporation	Antimicrobial elastomeric articles
US11039615B2 (en)	2014-04-18	2021-06-22	Entrotech Life Sciences, Inc.	Methods of processing chlorhexidine-containing polymerizable compositions and antimicrobial articles formed thereby
CN104910259A (zh) *	2015-06-02	2015-09-16	苏州纳微科技有限公司	一种替考拉宁的层析纯化方法
CN110463719A (zh) *	2018-12-29	2019-11-19	黑龙江大学	环丙沙星金属配合物-聚烯醇复合物及其制备方法和应用
CN114569588B (zh) *	2022-02-16	2023-09-26	湖南大学	洗必泰-万古霉素协同靶向抗菌应用
CN120303245A (zh) *	2022-12-06	2025-07-11	高露洁-棕榄公司	新的氯己定盐以及相关的组合物和方法
EP4670703A1 (fr)	2024-06-24	2025-12-31	Ivoclar Vivadent AG	Vernis dentaires à base de dispersions de polymères cationiques
EP4670702A1 (fr)	2024-06-24	2025-12-31	Ivoclar Vivadent AG	Vernis dentaires antimicrobiens à base de dispersions de polymères cationiques

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2002
- 2002-09-11 DE DE10242476A patent/DE10242476B4/de not_active Expired - Fee Related
2003
- 2003-08-27 CA CA2438346A patent/CA2438346C/fr not_active Expired - Fee Related
- 2003-08-29 AT AT03019738T patent/ATE300319T1/de active
- 2003-08-29 EP EP03019738A patent/EP1398046B1/fr not_active Expired - Lifetime
- 2003-08-29 DK DK03019738T patent/DK1398046T3/da active
- 2003-08-29 PT PT03019738T patent/PT1398046E/pt unknown
- 2003-08-29 DE DE50300849T patent/DE50300849D1/de not_active Expired - Lifetime
- 2003-08-29 ES ES03019738T patent/ES2242920T3/es not_active Expired - Lifetime
- 2003-09-03 AU AU2003244544A patent/AU2003244544B2/en not_active Ceased
- 2003-09-09 JP JP2003317448A patent/JP4528507B2/ja not_active Expired - Fee Related
- 2003-09-10 BR BR0303493-3A patent/BR0303493A/pt not_active IP Right Cessation
- 2003-09-10 ZA ZA200307059A patent/ZA200307059B/xx unknown
- 2003-09-11 CN CNA031589219A patent/CN1494925A/zh active Pending
- 2003-09-11 US US10/659,894 patent/US20040137065A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PT1398046E (pt)	2005-10-31
ZA200307059B (en)	2004-07-01
CA2438346C (fr)	2010-11-09
US20040137065A1 (en)	2004-07-15
ATE300319T1 (de)	2005-08-15
DE10242476B4 (de)	2006-10-26
AU2003244544B2 (en)	2005-08-04
CN1494925A (zh)	2004-05-12
BR0303493A (pt)	2004-09-08
DE50300849D1 (de)	2005-09-01
ES2242920T3 (es)	2005-11-16
AU2003244544A1 (en)	2004-03-25
DE10242476A1 (de)	2004-03-25
EP1398046B1 (fr)	2005-07-27
JP4528507B2 (ja)	2010-08-18
CA2438346A1 (fr)	2004-03-11
JP2004097822A (ja)	2004-04-02
EP1398046A1 (fr)	2004-03-17

Publication	Publication Date	Title
ATE300319T1 (de)	2005-08-15	Antibiotikum-/antibiotika-polymer-komposit
ATE252136T1 (de)	2003-11-15	Verträgliche fluorplastik-mischungen
EP0663409A4 (fr)	1995-12-20	Polymere antimicrobien, lentille de contact et produits d'entretien de lentilles de contact.
LU91908I2 (fr)	2012-01-30	Telavancine, ou un de ses sels pharmaceutiquement acceptable, y compris l'hydrochlorure de telavancine (VIBATIV®)
ES2163008T3 (es)	2002-01-16	Procedimiento para la obtencion de preparados de principios activos en forma de una disolucion solida de principio activo en una matriz polimera, asi como preparados de principios activos obtenidos con este procedimiento.
WO2004035008A3 (fr)	2004-11-04	Traitement d'infections et d'autres troubles
CA2033107A1 (fr)	1992-06-25	Surfaces ayant des proprietes steriles actives
EA200200476A1 (ru)	2003-02-27	Местный нецитотоксичный противомикробный гидрогель с тиксотропными свойствами
ATE352329T1 (de)	2007-02-15	Anb blockcopolymere mit vinylpyrrolidoneinheiten, medizinische geräte und methoden
DE69501957D1 (de)	1998-05-07	Sterilisierbare, polymere sauerstoffsperrfilms
AU2003291227A1 (en)	2004-06-07	Antibacterial agents
EP1560821B8 (fr)	2010-05-19	Agents antibacteriens
NZ502376A (en)	2000-11-24	Antifouling polymers comprising a polymer selected form EVA copolymer, HDPE, sodium ionomer and ethylene acrylic acid polmer, and a isothiazolone or furanone antifouling agent
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