DK1426355T3 - Krystaller af hydroxynorephedrinderivater - Google Patents

Krystaller af hydroxynorephedrinderivater

Info

Publication number: DK1426355T3
Authority: DK; Denmark
Prior art keywords: crystals; hydroxynorephedrine; derivatives; hydroxynorephedrine derivatives; methylethylüaminoüethylü
Prior art date: 2001-09-13

Application number

DK02765352T

Other languages

English (en)

Inventor

Hidetoshi Isawa

Yukihiko Hotei

Kiyoshi Kasai

Junichi Sonehara

Satoshi Akahane

Hiromu Harada

Original Assignee

Kissei Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-13

Filing date

2002-08-27

Publication date

2009-02-23

2002-08-27 Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical

2009-02-23 Application granted granted Critical

2009-02-23 Publication of DK1426355T3 publication Critical patent/DK1426355T3/da

Links

WXFIGDLSSYIKKV-RCOVLWMOSA-N L-Metaraminol Chemical class C[C@H](N)[C@H](O)C1=CC=CC(O)=C1 WXFIGDLSSYIKKV-RCOVLWMOSA-N 0.000 title 1
239000013078 crystal Substances 0.000 title 1
102000012367 Beta 3 adrenoceptor Human genes 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
206010036018 Pollakiuria Diseases 0.000 abstract 1
206010046543 Urinary incontinence Diseases 0.000 abstract 1
108040005346 beta3-adrenergic receptor activity proteins Proteins 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK02765352T 2001-09-13 2002-08-27 Krystaller af hydroxynorephedrinderivater DK1426355T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001277345		2001-09-13
PCT/JP2002/008596 WO2003024916A1 (en)	2001-09-13	2002-08-27	Crystals of hydroxynorephedrine derivative

Publications (1)

Publication Number	Publication Date
DK1426355T3 true DK1426355T3 (da)	2009-02-23

Family

ID=19101883

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02765352T DK1426355T3 (da)	2001-09-13	2002-08-27	Krystaller af hydroxynorephedrinderivater

Country Status (28)

Country	Link
US (1)	US7208520B2 (da)
EP (1)	EP1426355B1 (da)
JP (1)	JP4157036B2 (da)
KR (2)	KR20080098691A (da)
CN (1)	CN1275936C (da)
AT (1)	ATE411276T1 (da)
AU (1)	AU2002330453B2 (da)
BR (1)	BR0212494A (da)
CA (1)	CA2458544C (da)
CO (1)	CO5560555A2 (da)
CY (1)	CY1109409T1 (da)
DE (1)	DE60229404D1 (da)
DK (1)	DK1426355T3 (da)
EA (1)	EA006022B1 (da)
EC (1)	ECSP045017A (da)
ES (1)	ES2314092T3 (da)
HR (1)	HRP20040250A2 (da)
HU (1)	HUP0401694A3 (da)
IL (2)	IL160681A0 (da)
MX (1)	MXPA04002449A (da)
NO (1)	NO328252B1 (da)
NZ (1)	NZ531602A (da)
PL (1)	PL206246B1 (da)
PT (1)	PT1426355E (da)
SI (1)	SI1426355T1 (da)
UA (1)	UA77000C2 (da)
WO (1)	WO2003024916A1 (da)
ZA (1)	ZA200401757B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0210397D0 (en)	2002-05-07	2002-06-12	Ferring Bv	Pharmaceutical formulations
CA2524023C (en) *	2003-05-05	2011-11-22	Kissei Pharmaceutical Co., Ltd.	Use of phenoxyacetic acid derivatives for treating hyperactive bladder
DE10351271A1 (de) *	2003-10-31	2005-06-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmazeutische Zusammensetzung zur Behandlung der Stressinkontinenz und/oder Mischinkontinenz
WO2005042021A2 (de) *	2003-11-03	2005-05-12	Boehringer Ingelheim International Gmbh	Pharmazeutische zusammensetzung enthaltend einen beta-3-adrenozeptor-agonisten und einen alpha antagonisten und/oder einen 5-alpha reduktase-hemmer
DE10352132A1 (de) *	2003-11-04	2005-06-09	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem Alpha Agonisten
WO2005092321A1 (ja) *	2004-03-24	2005-10-06	Kissei Pharmaceutical Co., Ltd.	頻尿または尿失禁の予防または治療用医薬組成物
JP4808613B2 (ja) *	2004-03-24	2011-11-02	キッセイ薬品工業株式会社	頻尿または尿失禁の予防または治療用医薬
ES2291780T3 (es) *	2004-06-28	2008-03-01	Grunenthal Gmbh	Formas cristalinas del clorhidrato de (-)-(1r,2r)-3-(3-dimetilamino-1-etil-2-metilpropil)fenol.
DE102004050952A1 (de) *	2004-10-18	2006-04-20	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmazeutische Zusammensetzung zur Behandlung von Beschwerden, die mit krankhaften Veränderungen oder Irritationen der Prostata verbunden sind
JP2008516909A (ja) *	2004-10-18	2008-05-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	前立腺及び下部泌尿生殖路の病気を治療するためのβ−３アゴニストの使用
EP1809591A1 (en)	2004-10-26	2007-07-25	Kissei Pharmaceutical Co., Ltd.	Synthesis of phenoxyacetic acid derivatives
TWI356699B (en)	2004-11-10	2012-01-21	Kissei Pharmaceutical	Agent for treating interstitial cystitis and agent
JPWO2006123517A1 (ja) *	2005-04-26	2008-12-25	キッセイ薬品工業株式会社	ヒドロキシノルエフェドリン誘導体塩酸塩の結晶多形
US8003694B2 (en)	2005-04-26	2011-08-23	Kissei Pharmaceutical Co., Ltd.	Crystal of hydroxynorephedrin derivative hydrochloride ¼ hydrate
EP1769792A1 (de)	2005-09-30	2007-04-04	Boehringer Ingelheim Pharma GmbH & Co.KG	Verwendung eines beta-3-Adrenozeptor-Agonisten zur Behandlung von Nieren- und Blasenbeschwerden
WO2009021007A1 (en)	2007-08-06	2009-02-12	Serenity Pharmaceuticals Corporation	Methods and devices for desmopressin drug delivery
NO3085381T3 (da)	2008-05-21	2018-09-15
US20100286045A1 (en)	2008-05-21	2010-11-11	Bjarke Mirner Klein	Methods comprising desmopressin
US11963995B2 (en)	2008-05-21	2024-04-23	Ferring B.V.	Methods comprising desmopressin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY126489A (en) *	1998-07-08	2006-10-31	Kissei Pharmaceutical	Phenoxyacetic acid derivatives and medicinal compositions containing the same
JP4005729B2 (ja)	1999-01-21	2007-11-14	キッセイ薬品工業株式会社	アミノエチルフェノキシ酢酸誘導体二水和物の結晶多形
JP4005730B2 (ja)	1999-01-21	2007-11-14	キッセイ薬品工業株式会社	アミノエチルフェノキシ酢酸誘導体二水和物の結晶多形
JP4005731B2 (ja)	1999-01-21	2007-11-14	キッセイ薬品工業株式会社	アミノエチルフェノキシ酢酸誘導体の結晶多形

2002
- 2002-08-27 KR KR1020087026126A patent/KR20080098691A/ko not_active Ceased
- 2002-08-27 BR BR0212494-7A patent/BR0212494A/pt not_active IP Right Cessation
- 2002-08-27 PT PT02765352T patent/PT1426355E/pt unknown
- 2002-08-27 KR KR1020047003545A patent/KR100874952B1/ko not_active Expired - Fee Related
- 2002-08-27 MX MXPA04002449A patent/MXPA04002449A/es active IP Right Grant
- 2002-08-27 EP EP02765352A patent/EP1426355B1/en not_active Expired - Lifetime
- 2002-08-27 UA UA2004031852A patent/UA77000C2/uk unknown
- 2002-08-27 WO PCT/JP2002/008596 patent/WO2003024916A1/ja not_active Ceased
- 2002-08-27 HR HR20040250A patent/HRP20040250A2/hr not_active Application Discontinuation
- 2002-08-27 SI SI200230775T patent/SI1426355T1/sl unknown
- 2002-08-27 AT AT02765352T patent/ATE411276T1/de active
- 2002-08-27 CA CA2458544A patent/CA2458544C/en not_active Expired - Fee Related
- 2002-08-27 IL IL16068102A patent/IL160681A0/xx unknown
- 2002-08-27 US US10/489,343 patent/US7208520B2/en not_active Expired - Fee Related
- 2002-08-27 CN CNB028175964A patent/CN1275936C/zh not_active Expired - Fee Related
- 2002-08-27 HU HU0401694A patent/HUP0401694A3/hu unknown
- 2002-08-27 AU AU2002330453A patent/AU2002330453B2/en not_active Ceased
- 2002-08-27 DK DK02765352T patent/DK1426355T3/da active
- 2002-08-27 PL PL367874A patent/PL206246B1/pl not_active IP Right Cessation
- 2002-08-27 DE DE60229404T patent/DE60229404D1/de not_active Expired - Lifetime
- 2002-08-27 ES ES02765352T patent/ES2314092T3/es not_active Expired - Lifetime
- 2002-08-27 EA EA200400311A patent/EA006022B1/ru not_active IP Right Cessation
- 2002-08-27 JP JP2003528764A patent/JP4157036B2/ja not_active Expired - Fee Related
2003
- 2003-08-27 NZ NZ531602A patent/NZ531602A/en not_active IP Right Cessation
2004
- 2004-03-02 IL IL160681A patent/IL160681A/en not_active IP Right Cessation
- 2004-03-03 ZA ZA200401757A patent/ZA200401757B/en unknown
- 2004-03-12 CO CO04022925A patent/CO5560555A2/es not_active Application Discontinuation
- 2004-03-12 EC EC2004005017A patent/ECSP045017A/es unknown
- 2004-03-12 NO NO20041060A patent/NO328252B1/no not_active IP Right Cessation
2009
- 2009-01-14 CY CY20091100027T patent/CY1109409T1/el unknown

Also Published As

Publication number	Publication date
CY1109409T1 (el)	2014-07-02
HUP0401694A3 (en)	2008-03-28
PL206246B1 (pl)	2010-07-30
EP1426355B1 (en)	2008-10-15
KR20080098691A (ko)	2008-11-11
AU2002330453B2 (en)	2008-04-17
IL160681A (en)	2010-06-16
ECSP045017A (es)	2004-09-27
NO20041060L (no)	2004-06-11
JPWO2003024916A1 (ja)	2004-12-24
CO5560555A2 (es)	2005-09-30
JP4157036B2 (ja)	2008-09-24
ATE411276T1 (de)	2008-10-15
EA200400311A1 (ru)	2004-08-26
HK1070051A1 (en)	2005-06-10
BR0212494A (pt)	2004-08-24
CN1553890A (zh)	2004-12-08
DE60229404D1 (de)	2008-11-27
NZ531602A (en)	2006-01-27
HRP20040250A2 (en)	2005-02-28
UA77000C2 (en)	2006-10-16
EA006022B1 (ru)	2005-08-25
HUP0401694A2 (hu)	2004-11-29
CA2458544A1 (en)	2003-03-27
US20040242686A1 (en)	2004-12-02
CN1275936C (zh)	2006-09-20
PL367874A1 (en)	2005-03-07
EP1426355A4 (en)	2006-03-29
ZA200401757B (en)	2005-03-03
US7208520B2 (en)	2007-04-24
KR20040044881A (ko)	2004-05-31
EP1426355A1 (en)	2004-06-09
CA2458544C (en)	2010-08-17
SI1426355T1 (sl)	2009-02-28
ES2314092T3 (es)	2009-03-16
MXPA04002449A (es)	2004-07-23
PT1426355E (pt)	2008-11-03
NO328252B1 (no)	2010-01-18
WO2003024916A1 (en)	2003-03-27
IL160681A0 (en)	2004-08-31
KR100874952B1 (ko)	2008-12-19

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NO20041060L (no)	2004-06-11	Krystaller av hydroksynorefedrinderivat
IS2750B (is)	2011-08-15	Leiðarafesting
MXPA04002167A (es)	2004-06-29	Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
NO20020968L (no)	2002-04-26	Glukopyranosyloksypyrazolderivater, medisinske sammensetninger inneholdende det samme og intermediater forfremstillingen derav
NO20051209L (no)	2005-04-15	Pyrazolderivater, medisinske sammensetninger inneholdende slike, medisinsk anvendelse derav samt intermediater for samme
CY1109880T1 (el)	2014-09-10	ΑΝΤΑΓΩΝΙΣΤΗΣ CaSR
BR0210383A (pt)	2006-04-04	compostos para o tratamento de distúrbios metabólicos
PT1259489E (pt)	2006-08-31	Compostos azapoliciclicos condensados con arilo.
DK1767535T3 (da)	2010-04-12	Syntese af epothiloner, mellemprodukter deraf, analoge og deres anvendelse
SE0201544D0 (sv)	2002-05-17	Novel compounds and thier use
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ATE438626T1 (de)	2009-08-15	4,4-difluor-1,2,3,4-tetrahydro-5h-1- benzazepinderivate und deren salze
BR0316723A (pt)	2005-10-18	Derivados de anilinopirazol úteis para o tratamento de diabetes
NO304113B1 (no)	1998-10-26	Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament
CY1111857T1 (el)	2015-11-04	Κρυσταλλικη βαση trans-1-((1r,3s)-6-xλωpo-3-φαινυλινδαν-1-υλο)-3,3-διμεθυλοπιπεραζινης
WO2004041802A8 (en)	2005-03-10	4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders
IS6087A (is)	2001-09-26	N-(2-fenýl-4-amínó-bútýl)-1-naftamíð sem virka á móti taugakínín-1 viðtaka
BRPI0507735A (pt)	2007-07-10	composição para administração oral de cloridrato de tamsulosin e formulação de gránulo de liberação controlada compreendendo a mesma
WO2000056315A8 (en)	2001-06-21	Treatment of pain
BR0206841A (pt)	2004-02-25	Modificação cristalina de um depsipeptìdeo cìclico com melhor eficácia
BRPI0513549A (pt)	2008-05-06	composições farmacêuticas para o tratamento de leishmaniose
DE60300683D1 (de)	2005-06-23	Prucaloprid-n-oxid
MXPA01009461A (es)	2004-03-19	Tratamiento de osteoartritis.
DK1496904T3 (da)	2007-11-12	Anvendelse af lægemidler indeholdende N,N'-disubstituerede piperazinforbindelser
DE60238847D1 (de)	2011-02-17	Pyrimidinderivate enthaltendes medikament