DK1427720T3 - 3-substitueret-4-pyrimidonderivater - Google Patents

3-substitueret-4-pyrimidonderivater

Info

Publication number: DK1427720T3
Authority: DK; Denmark
Prior art keywords: sup; sub; substituted; ring; group
Prior art date: 2001-09-21

Application number

DK02772871T

Other languages

Danish (da)

English (en)

Inventor

Fumiaki Uehara

Keiichi Aritomo

Aya Shoda

Shinsuke Hiki

Masahiro Okuyama

Yoshihiro Usui

Mitsuru Ooizumi

Kazutoshi Watanabe

Koichi Yamakoshi

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-21

Filing date

2002-09-20

Publication date

2009-05-04

2002-09-20 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2009-05-04 Application granted granted Critical

2009-05-04 Publication of DK1427720T3 publication Critical patent/DK1427720T3/da

Links

-1 3-substituted-4-pyrimidone Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004429 atom Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
PQNFLJBBNBOBRQ-UHFFFAOYSA-N indane Chemical group C1=CC=C2CCCC2=C1 PQNFLJBBNBOBRQ-UHFFFAOYSA-N 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000008318 pyrimidones Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1
108010061506 tau-protein kinase Proteins 0.000 abstract 1
CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical group C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Psychology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK02772871T 2001-09-21 2002-09-20 3-substitueret-4-pyrimidonderivater DK1427720T3 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
JP2001331675		2001-09-21
JP2001331674		2001-09-21
JP2001331677		2001-09-21
JP2001331678		2001-09-21
PCT/JP2002/009685 WO2003037888A1 (en)	2001-09-21	2002-09-20	3-substituted-4-pyrimidone derivatives

Publications (1)

Publication Number	Publication Date
DK1427720T3 true DK1427720T3 (da)	2009-05-04

Family

ID=27482651

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02772871T DK1427720T3 (da)	2001-09-21	2002-09-20	3-substitueret-4-pyrimidonderivater

Country Status (24)

Country	Link
US (1)	US7427615B2 (de)
EP (1)	EP1427720B1 (de)
JP (1)	JP4347050B2 (de)
KR (1)	KR100881821B1 (de)
CN (1)	CN100488958C (de)
AT (1)	ATE424393T1 (de)
AU (1)	AU2002337499B2 (de)
BR (1)	BR0212892A (de)
CA (1)	CA2460121C (de)
CY (1)	CY1110317T1 (de)
DE (1)	DE60231414D1 (de)
DK (1)	DK1427720T3 (de)
EA (1)	EA007576B1 (de)
ES (1)	ES2323576T3 (de)
HU (1)	HUP0401900A3 (de)
IL (2)	IL160700A0 (de)
MX (1)	MXPA04002662A (de)
NO (1)	NO325781B1 (de)
NZ (1)	NZ531636A (de)
PL (1)	PL368671A1 (de)
PT (1)	PT1427720E (de)
SI (1)	SI1427720T1 (de)
TW (1)	TWI265164B (de)
WO (1)	WO2003037888A1 (de)

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KR100754596B1 (ko)	2001-09-21	2007-09-05	미쯔비시 웰 파마 가부시키가이샤	3-치환-4-피리미돈 유도체
MXPA05006394A (es) *	2002-12-16	2007-04-16	Mitsubishi Pharma Corp	Derivados de 4-pirimidona 3-sustituida.
US7550590B2 (en)	2003-03-25	2009-06-23	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
TWI357408B (en) *	2003-03-26	2012-02-01	Mitsubishi Tanabe Pharma Corp	3-substituted-4-pyrimidone derivatives
KR20060041309A (ko)	2003-08-13	2006-05-11	다케다 야쿠힌 고교 가부시키가이샤	４-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
US7790734B2 (en)	2003-09-08	2010-09-07	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
GB0325956D0 (en)	2003-11-06	2003-12-10	Addex Pharmaceuticals Sa	Novel compounds
CN102127057A (zh)	2004-03-15	2011-07-20	武田药品工业株式会社	二肽基肽酶抑制剂
AR050865A1 (es) *	2004-09-09	2006-11-29	Sanofi Aventis	Derivados de 2- morfolino-4-pirimidona
PT1805164E (pt) *	2004-09-29	2011-04-11	Sanofi Aventis	Derivados de 6-(piridinil)-4-pirimidona como inibidores de proteína-cinase tau 1
WO2006041405A1 (en) *	2004-10-15	2006-04-20	Astrazeneca Ab	Substituted amino-pyrimidones and uses thereof
EP1802587A4 (de) *	2004-10-15	2010-02-17	Astrazeneca Ab	Substituierte aminoverbindungen und deren anwendungen
WO2006068978A2 (en)	2004-12-21	2006-06-29	Takeda Pharmaceutial Company Limited	Dipeptidyl peptidase inhibitors
GB0510142D0 (en) *	2005-05-18	2005-06-22	Addex Pharmaceuticals Sa	Novel compounds A1
GB0510141D0 (en)	2005-05-18	2005-06-22	Addex Pharmaceuticals Sa	Novel compounds B3
GEP20135838B (en)	2005-09-14	2013-06-10	Takeda Pharmaceutical	Dipeptidyl peptidase inhibitors usage at diabetes treatment
CN101360723A (zh)	2005-09-16	2009-02-04	武田药品工业株式会社	制备嘧啶二酮衍生物的方法
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US8324383B2 (en)	2006-09-13	2012-12-04	Takeda Pharmaceutical Company Limited	Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en)	2006-11-29	2008-10-01	Takeda Pharmaceutical	Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
AR064660A1 (es) *	2006-12-26	2009-04-15	Mitsubishi Tanabe Pharma Corp	Derivados de pirimidinona 6-heterociclica 2-sustituida, medicamentos que los contienen y usos para prevenir y/o tratar enfermedades neurodegenerativas entre otras
US8093236B2 (en)	2007-03-13	2012-01-10	Takeda Pharmaceuticals Company Limited	Weekly administration of dipeptidyl peptidase inhibitors
CN101842371A (zh) *	2007-09-14	2010-09-22	赛诺菲-安万特公司	3-甲基-2-((2S)-2-(4-(3-甲基-1,2,4-噁二唑-5-基)苯基)吗啉基)-6-(嘧啶-4-基)嘧啶-4(3H)-酮作为tau蛋白激酶抑制剂
AU2008297817A1 (en)	2007-09-14	2009-03-19	Mitsubishi Tanabe Pharma Corporation	6-pyrimidinyl-pyrimid-4-one derivative
AR076014A1 (es) *	2009-04-02	2011-05-11	Sanofi Aventis	Derivados de 3- (1,4) oxazepan -4-pirimidona
WO2011019089A1 (en)	2009-08-13	2011-02-17	Mitsubishi Tanabe Pharma Corporation	Pyrimidone derivatives used as tau protein kinase 1 inhibitors
WO2011019090A1 (en)	2009-08-13	2011-02-17	Mitsubishi Tanabe Pharma Corporation	Pyrimidone derivatives used as tau protein kinase 1 inhibitors
US20130123281A1 (en) *	2011-11-11	2013-05-16	Beta Cat Pharmaceuticals, Llc	Compositions and Methods for Inhibition of TBL-1 Binding to Disease-Associated Molecules
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WO2001070728A1 (en)	2000-03-23	2001-09-27	Sanofi-Synthelabo	2-[nitrogen-heterocyclic]pyrimidone derivatives
EP1136482A1 (de)	2000-03-23	2001-09-26	Sanofi-Synthelabo	2-Amino-3-(alkyl)-pyrimidonderivate als GSK3beta-Hemmer
KR100754596B1 (ko)	2001-09-21	2007-09-05	미쯔비시 웰 파마 가부시키가이샤	3-치환-4-피리미돈 유도체
MXPA05006394A (es)	2002-12-16	2007-04-16	Mitsubishi Pharma Corp	Derivados de 4-pirimidona 3-sustituida.
TWI357408B (en)	2003-03-26	2012-02-01	Mitsubishi Tanabe Pharma Corp	3-substituted-4-pyrimidone derivatives

2002
- 2002-09-20 AU AU2002337499A patent/AU2002337499B2/en not_active Ceased
- 2002-09-20 TW TW091121655A patent/TWI265164B/zh not_active IP Right Cessation
- 2002-09-20 KR KR1020047004112A patent/KR100881821B1/ko not_active Expired - Fee Related
- 2002-09-20 MX MXPA04002662A patent/MXPA04002662A/es active IP Right Grant
- 2002-09-20 EA EA200400453A patent/EA007576B1/ru not_active IP Right Cessation
- 2002-09-20 NZ NZ531636A patent/NZ531636A/en not_active IP Right Cessation
- 2002-09-20 WO PCT/JP2002/009685 patent/WO2003037888A1/en not_active Ceased
- 2002-09-20 BR BR0212892-6A patent/BR0212892A/pt not_active Application Discontinuation
- 2002-09-20 PT PT02772871T patent/PT1427720E/pt unknown
- 2002-09-20 US US10/489,606 patent/US7427615B2/en not_active Expired - Fee Related
- 2002-09-20 AT AT02772871T patent/ATE424393T1/de active
- 2002-09-20 DK DK02772871T patent/DK1427720T3/da active
- 2002-09-20 IL IL16070002A patent/IL160700A0/xx unknown
- 2002-09-20 EP EP02772871A patent/EP1427720B1/de not_active Expired - Lifetime
- 2002-09-20 DE DE60231414T patent/DE60231414D1/de not_active Expired - Lifetime
- 2002-09-20 CA CA2460121A patent/CA2460121C/en not_active Expired - Fee Related
- 2002-09-20 HU HU0401900A patent/HUP0401900A3/hu unknown
- 2002-09-20 JP JP2003540169A patent/JP4347050B2/ja not_active Expired - Fee Related
- 2002-09-20 SI SI200230816T patent/SI1427720T1/sl unknown
- 2002-09-20 ES ES02772871T patent/ES2323576T3/es not_active Expired - Lifetime
- 2002-09-20 PL PL02368671A patent/PL368671A1/xx unknown
- 2002-09-20 CN CNB028184696A patent/CN100488958C/zh not_active Expired - Fee Related
2004
- 2004-03-03 IL IL160700A patent/IL160700A/en not_active IP Right Cessation
- 2004-04-20 NO NO20041600A patent/NO325781B1/no not_active IP Right Cessation
2009
- 2009-05-28 CY CY20091100562T patent/CY1110317T1/el unknown

Also Published As

Publication number	Publication date
SI1427720T1 (sl)	2009-08-31
EP1427720A1 (de)	2004-06-16
HUP0401900A2 (hu)	2004-12-28
ATE424393T1 (de)	2009-03-15
MXPA04002662A (es)	2004-11-22
JP4347050B2 (ja)	2009-10-21
US20050090490A1 (en)	2005-04-28
AU2002337499B2 (en)	2007-08-23
CY1110317T1 (el)	2015-01-14
CA2460121C (en)	2010-11-02
ES2323576T3 (es)	2009-07-21
CN100488958C (zh)	2009-05-20
EA200400453A1 (ru)	2004-08-26
TWI265164B (en)	2006-11-01
PL368671A1 (en)	2005-04-04
EA007576B1 (ru)	2006-12-29
WO2003037888A1 (en)	2003-05-08
PT1427720E (pt)	2009-04-27
NZ531636A (en)	2005-11-25
CA2460121A1 (en)	2003-05-08
NO20041600L (no)	2004-06-16
US7427615B2 (en)	2008-09-23
DE60231414D1 (de)	2009-04-16
HUP0401900A3 (en)	2005-08-29
IL160700A (en)	2009-09-22
EP1427720B1 (de)	2009-03-04
KR20040054689A (ko)	2004-06-25
CN1556804A (zh)	2004-12-22
JP2005510506A (ja)	2005-04-21
NO325781B1 (no)	2008-07-14
BR0212892A (pt)	2004-08-03
IL160700A0 (en)	2004-08-31
KR100881821B1 (ko)	2009-02-03

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