DK1439220T3 - Immobiliserede biokatalysatorer der kan anvendes til fremstilling af naturlige nukleosider og modificerede analoger ved enzymatiske transglycosyleringsreaktioner - Google Patents

Immobiliserede biokatalysatorer der kan anvendes til fremstilling af naturlige nukleosider og modificerede analoger ved enzymatiske transglycosyleringsreaktioner

Info

Publication number
DK1439220T3
DK1439220T3 DK03425018T DK03425018T DK1439220T3 DK 1439220 T3 DK1439220 T3 DK 1439220T3 DK 03425018 T DK03425018 T DK 03425018T DK 03425018 T DK03425018 T DK 03425018T DK 1439220 T3 DK1439220 T3 DK 1439220T3
Authority
DK
Denmark
Prior art keywords
biocatalysts
natural nucleosides
modified analogues
prepare natural
immobilized biocatalysts
Prior art date
Application number
DK03425018T
Other languages
English (en)
Inventor
Giancarlo Tonon
Emanuele Capra
Gaetano Orsini
Gabriele Zuffi
Original Assignee
Adorkem Technology Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adorkem Technology Spa filed Critical Adorkem Technology Spa
Application granted granted Critical
Publication of DK1439220T3 publication Critical patent/DK1439220T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02003—Uridine phosphorylase (2.4.2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/18—Multi-enzyme systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/385—Pyrimidine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02001—Purine-nucleoside phosphorylase (2.4.2.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
DK03425018T 2003-01-16 2003-01-16 Immobiliserede biokatalysatorer der kan anvendes til fremstilling af naturlige nukleosider og modificerede analoger ved enzymatiske transglycosyleringsreaktioner DK1439220T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03425018A EP1439220B1 (en) 2003-01-16 2003-01-16 Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions

Publications (1)

Publication Number Publication Date
DK1439220T3 true DK1439220T3 (da) 2007-12-27

Family

ID=32524299

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03425018T DK1439220T3 (da) 2003-01-16 2003-01-16 Immobiliserede biokatalysatorer der kan anvendes til fremstilling af naturlige nukleosider og modificerede analoger ved enzymatiske transglycosyleringsreaktioner

Country Status (9)

Country Link
US (1) US20040142438A1 (da)
EP (1) EP1439220B1 (da)
AT (1) ATE371021T1 (da)
CY (1) CY1107015T1 (da)
DE (1) DE60315790T2 (da)
DK (1) DK1439220T3 (da)
ES (1) ES2292927T3 (da)
PT (1) PT1439220E (da)
SI (1) SI1439220T1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241586B2 (en) * 2005-02-17 2007-07-10 Medtronic Minimed, Inc. Polypeptide formulations and methods for making, using and characterizing them
CN100379859C (zh) * 2005-03-04 2008-04-09 上海秋之友生物科技有限公司 固定化核苷磷酸化酶微生物及其在合成嘌呤核苷中的应用
US20070065922A1 (en) * 2005-09-21 2007-03-22 Metkinen Oy Biocatalytic synthesis of aminodeoxy purine N9-beta-D-nucleosides containing 3-amino-3-deoxy-beta-D-ribofuranose, 3-amino-2,3-dideoxy-beta-D-ribofuranose, and 2-amino-2-deoxy-beta-D-ribofuranose as sugar moieties
ATE458065T1 (de) * 2006-03-15 2010-03-15 Explora Lab Sa Verfahren zur immobilisierung von zellen auf harzen
EP1932918B1 (en) 2006-12-15 2009-09-16 EXPLORA Laboratories SA Method for the production of cladribine
RU2368662C1 (ru) * 2008-06-27 2009-09-27 Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН СПОСОБ ПОЛУЧЕНИЯ 9-(β-D-АРАБИНОФУРАНОЗИЛ)-2-ФТОРАДЕНИНА

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5314810A (en) * 1987-11-25 1994-05-24 Meiji Seika Kaisha, Ltd. Fructose transferring enzyme absorbed on a granular carrier for production of fructooligosaccharides
IL90600A0 (en) * 1988-06-16 1990-01-18 Du Pont Polynucleotide phosphorylase immobilized on epoxy-activated beads
US5187296A (en) * 1988-12-07 1993-02-16 Bromine Compounds Limited Cyanohydrination process
IL88618A (en) * 1988-12-07 1993-02-21 Bromine Compounds Ltd Chiral cyanohydrination of m-phenoxybenzaldehyde over polymer-supported cyclo (phenylalanyl- histidine)
EP0596943B1 (en) * 1991-07-31 1996-11-20 Warner-Lambert Company Process for purifying pentostatin
JP4003093B2 (ja) * 1997-07-29 2007-11-07 東洋紡績株式会社 糖類の製造方法
ITMI20011537A1 (it) * 2001-07-19 2003-01-19 Pro Bio Sint Srl Transglicosilazione di nucleosidi mediante biocatalisi con enzimi immobilizzati e stabilizzati

Also Published As

Publication number Publication date
ATE371021T1 (de) 2007-09-15
DE60315790T2 (de) 2008-06-05
ES2292927T3 (es) 2008-03-16
SI1439220T1 (sl) 2007-12-31
US20040142438A1 (en) 2004-07-22
CY1107015T1 (el) 2012-09-26
DE60315790D1 (de) 2007-10-04
EP1439220B1 (en) 2007-08-22
PT1439220E (pt) 2007-11-28
EP1439220A1 (en) 2004-07-21

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