DK1440152T3 - 5t4-ligand - Google Patents

5t4-ligand

Info

Publication number
DK1440152T3
DK1440152T3 DK02772604.1T DK02772604T DK1440152T3 DK 1440152 T3 DK1440152 T3 DK 1440152T3 DK 02772604 T DK02772604 T DK 02772604T DK 1440152 T3 DK1440152 T3 DK 1440152T3
Authority
DK
Denmark
Prior art keywords
ligand
Prior art date
Application number
DK02772604.1T
Other languages
English (en)
Inventor
Miles Carroll
Abigail Lamikanra
Alan Kingsman
Original Assignee
Oxford Biomedica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biomedica Ltd filed Critical Oxford Biomedica Ltd
Application granted granted Critical
Publication of DK1440152T3 publication Critical patent/DK1440152T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK02772604.1T 2001-11-02 2002-11-04 5t4-ligand DK1440152T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0126378.9A GB0126378D0 (en) 2001-11-02 2001-11-02 Antigen
PCT/GB2002/004965 WO2003038098A2 (en) 2001-11-02 2002-11-04 5t4 ligand

Publications (1)

Publication Number Publication Date
DK1440152T3 true DK1440152T3 (da) 2013-07-29

Family

ID=9925057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02772604.1T DK1440152T3 (da) 2001-11-02 2002-11-04 5t4-ligand

Country Status (6)

Country Link
US (4) US20050175618A1 (da)
EP (1) EP1440152B1 (da)
DK (1) DK1440152T3 (da)
ES (1) ES2430968T3 (da)
GB (1) GB0126378D0 (da)
WO (1) WO2003038098A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
MXPA05001933A (es) * 2002-08-19 2005-04-28 Genentech Inc Composiciones y metodos para el diagnostico y tratamiento de tumores.
SV2007002227A (es) * 2004-09-10 2007-03-20 Wyeth Corp Anticuerpos anti-5t4 humanizados y conjugados anticuerpo anti-5t4/calicheamicina ref. 040000-0317637
DK2368914T3 (da) * 2006-03-10 2019-03-04 Wyeth Llc Anti-5T4-antistoffer og anvendelser deraf
AU2013216628C1 (en) * 2006-03-10 2016-02-04 Wyeth Llc Anti-5t4 antibodies and uses thereof
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
AU2010325969B2 (en) 2009-12-02 2016-10-20 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
KR101716555B1 (ko) 2012-01-24 2017-03-14 화이자 인코포레이티드 포유동물 대상체에서 5t4-양성 순환 종양 세포를 검출하는 방법 및 5t4-양성 암을 진단하는 방법
JP2016540826A (ja) 2013-11-04 2016-12-28 ファイザー・インク 抗efna4抗体−薬物コンジュゲート
WO2015155345A1 (en) * 2014-04-11 2015-10-15 Medimmune Limited Antibodies and antibody-drug conjugates
EA035419B9 (ru) 2014-05-29 2020-08-07 Мэкроудженикс, Инк. Триспецифичные связывающие молекулы и способы их применения
EP3190685B1 (en) * 2014-09-02 2019-02-13 Panasonic Intellectual Property Management Co., Ltd. Contactless power receiver, contactless power feeder, and contactless power transmission system provided with same
US11254744B2 (en) 2015-08-07 2022-02-22 Imaginab, Inc. Antigen binding constructs to target molecules
AU2016358854B2 (en) * 2015-11-24 2023-02-02 Byondis B.V. Anti-5T4 antibodies and antibody-drug conjugates
WO2017107973A1 (zh) * 2015-12-24 2017-06-29 凯惠科技发展(上海)有限公司 一种tpbg抗体及其制备方法、其偶联物和应用
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies
KR20230166145A (ko) 2017-03-15 2023-12-06 옥스포드 바이오메디카(유케이) 리미티드 방법
SG11202008399QA (en) 2018-03-12 2020-09-29 Genmab As Antibodies
WO2021048423A1 (en) 2019-09-12 2021-03-18 Genmab A/S Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer
WO2026024644A1 (en) 2024-07-23 2026-01-29 Abdera Therapeutics Inc. 5t4 binding polypeptides and uses thereof

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US239400A (en) 1881-03-29 Tobacco-fork
NL86231C (da) * 1952-09-20
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
IL74497A (en) * 1985-03-05 1990-02-09 Proterra Ag Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US4997913A (en) * 1986-06-30 1991-03-05 Oncogen pH-sensitive immunoconjugates and methods for their use in tumor therapy
ATE243754T1 (de) 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
EP0403559A1 (en) 1988-03-04 1990-12-27 Cancer Research Campaign Technology Limited Improvements relating to antigens
US5591624A (en) * 1988-03-21 1997-01-07 Chiron Viagene, Inc. Retroviral packaging cell lines
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
JP2501886B2 (ja) 1988-11-16 1996-05-29 日産自動車株式会社 車体組み立て方法
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
US5582826A (en) * 1993-04-21 1996-12-10 Ajinomoto Co., Inc. Monoclonal antibodies which bind the gamma chain of human interleukin-2 receptor
GB9324807D0 (en) * 1993-12-03 1994-01-19 Cancer Res Campaign Tech Tumour antibody
US5559099A (en) * 1994-09-08 1996-09-24 Genvec, Inc. Penton base protein and methods of using same
DE69523857T2 (de) * 1994-09-16 2002-06-13 Merck Patent Gmbh Immunokonjugate
CA2234931C (en) * 1995-10-16 2010-01-19 Dana-Farber Cancer Institute Novel expression vectors and methods of use
SE9601245D0 (sv) * 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
US5998423A (en) * 1996-10-08 1999-12-07 Therasys, Inc. Methods for modulating melanin production
US6348584B1 (en) * 1996-10-17 2002-02-19 John Edward Hodgson Fibronectin binding protein compounds
US6852703B1 (en) * 1997-06-04 2005-02-08 Oxford Biomedica (Uk) Limited Tumor targeted vector
DE69934694T2 (de) * 1998-08-10 2007-10-04 Agensys, Inc., Santa Monica Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird
EP1036091B2 (en) 1998-11-18 2008-03-26 Oxford Biomedica (UK) Limited 5t4 tumour-associated antigen for use in tumour immunotherapy
JP2003515323A (ja) * 1999-11-18 2003-05-07 オックスフォード バイオメディカ(ユーケイ)リミテッド 抗 体
ATE411342T1 (de) * 1999-11-18 2008-10-15 Oxford Biomedica Ltd Scfv antikörper gegen krankheiten-assoziierte moleküle
SE0102327D0 (sv) * 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
US6875425B2 (en) * 2002-12-12 2005-04-05 Unilever Home & Personal Care Usa Skin lightening agents, compositions and methods
US7247294B1 (en) * 2006-03-30 2007-07-24 Conopco, Inc. Skin lightening agents, compositions and methods
US7270805B1 (en) * 2006-03-30 2007-09-18 Conopco, Inc. Skin lightening agents, compositions and methods
US7250158B1 (en) * 2006-03-30 2007-07-31 Conopco, Inc. Skin lightening agents, compositions and methods

Also Published As

Publication number Publication date
EP1440152B1 (en) 2013-04-24
US20090155290A1 (en) 2009-06-18
GB0126378D0 (en) 2002-01-02
WO2003038098A2 (en) 2003-05-08
US20100310584A1 (en) 2010-12-09
EP1440152A2 (en) 2004-07-28
US20050175618A1 (en) 2005-08-11
US20130236479A1 (en) 2013-09-12
ES2430968T3 (es) 2013-11-22
WO2003038098A3 (en) 2003-06-12

Similar Documents

Publication Publication Date Title
ATE524462T1 (de) C5-modifizierte indazolylpyrrolotriazine
DE50214313D1 (de) Koaxialmagentventil
DE50208022D1 (de) Wischblatt
DE50206021D1 (de) Schlauchklemme
DE50103741D1 (de) Welle-Nabe-Verbindung
DE50212173D1 (de) sgängern
DE50209238D1 (de) Kugelgelenk
DE50204551D1 (de) Kugelgelenk
EP1434599A4 (en) HUMAN RELAXINE 3
ATE335486T1 (de) Hydrazono-malonitrile
DE50211604D1 (de) Chlag
DK1440152T3 (da) 5t4-ligand
DE50209410D1 (de) Kugelgelenk
DE50208372D1 (de) Schrankaufhängevorrichtung
DE50211290D1 (de) Handzange
DE50203412D1 (de) Schwenkkolbenverdränger
DE50204794D1 (de) Kugelgelenk
DE50203984D1 (de) Kugelgelenk
ATE355059T1 (de) Isoxazolopyridinone
DE50208029D1 (de) Kugelgelenk
DE50201862D1 (de) Messwandler
DE50203093D1 (de) Losradlager
ATA18372001A (de) Gelenksbolzenbaueinheit
ATE319694T1 (de) Phenylalkyne
DE50209293D1 (de) Amidpolymermasse