DK1443328T3 - Cobalamin-assay - Google Patents

Cobalamin-assay

Info

Publication number: DK1443328T3
Authority: DK; Denmark
Prior art keywords: cobalamin; bound; ligand; holo; tcii
Prior art date: 1998-09-18

Application number

DK04009702T

Other languages

Danish (da)

English (en)

Inventor

Erling Sundrehagen

Lars Oerning

Original Assignee

Axis Shield Asa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-18

Filing date

1999-09-20

Publication date

2007-09-24

1999-09-20 Application filed by Axis Shield Asa filed Critical Axis Shield Asa

2007-09-24 Application granted granted Critical

2007-09-24 Publication of DK1443328T3 publication Critical patent/DK1443328T3/da

Links

FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 title abstract 4
238000003556 assay Methods 0.000 title abstract 2
102100040423 Transcobalamin-2 Human genes 0.000 abstract 3
102000011409 Transcobalamins Human genes 0.000 abstract 3
108010023603 Transcobalamins Proteins 0.000 abstract 3
239000003446 ligand Substances 0.000 abstract 3
210000001124 body fluid Anatomy 0.000 abstract 1
239000010839 body fluid Substances 0.000 abstract 1
230000009870 specific binding Effects 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
General Physics & Mathematics (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Liquid Developers In Electrophotography (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Cable Accessories (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Lubrication Of Internal Combustion Engines (AREA)
Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
Measuring And Recording Apparatus For Diagnosis (AREA)
Mechanical Treatment Of Semiconductor (AREA)
Analysing Materials By The Use Of Radiation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Glass Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Polyamides (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK04009702T 1998-09-18 1999-09-20 Cobalamin-assay DK1443328T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9820473.8A GB9820473D0 (en)	1998-09-18	1998-09-18	Assay
PCT/GB1999/003127 WO2000017659A1 (en)	1998-09-18	1999-09-20	Cobalamin assay

Publications (1)

Publication Number	Publication Date
DK1443328T3 true DK1443328T3 (da)	2007-09-24

Family

ID=10839158

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04009702T DK1443328T3 (da)	1998-09-18	1999-09-20	Cobalamin-assay

Country Status (22)

Country	Link
US (1)	US7279283B1 (de)
EP (2)	EP1114323B1 (de)
JP (1)	JP4394285B2 (de)
KR (2)	KR100781014B1 (de)
CN (2)	CN1322330C (de)
AT (2)	ATE283490T1 (de)
AU (1)	AU761498B2 (de)
BR (1)	BR9913770A (de)
CA (1)	CA2344193C (de)
CY (1)	CY1106688T1 (de)
CZ (2)	CZ298310B6 (de)
DE (2)	DE69922225T2 (de)
DK (1)	DK1443328T3 (de)
ES (2)	ES2234299T3 (de)
GB (1)	GB9820473D0 (de)
HU (1)	HU228077B1 (de)
MX (1)	MXPA01002591A (de)
NO (2)	NO327771B1 (de)
NZ (1)	NZ510766A (de)
PL (2)	PL201360B1 (de)
PT (2)	PT1114323E (de)
WO (1)	WO2000017659A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0016460D0 (en) *	2000-07-04	2000-08-23	Axis Shield Asa	Assay
GB0109925D0 (en) *	2001-04-23	2001-06-13	Axis Shield Asa	Method
CN104903152B (zh)	2012-11-06	2017-06-13	现代自动车株式会社	高耐热隔音吸声材料的制造方法
CN104198598B (zh) *	2014-07-15	2016-03-16	汤臣倍健股份有限公司	一种维生素b12的测定方法
CN106841017B (zh) *	2017-01-22	2019-05-07	耐斯检测技术服务有限公司	一种评价辐照或热处理对钴胺素-蛋白结合体影响的方法
CN106693443A (zh) *	2017-01-23	2017-05-24	北京美正生物科技有限公司	一种维生素b12适配体亲和柱及其制备方法和用途
EP4010005A4 (de)	2019-08-09	2022-11-23	Siemens Healthcare Diagnostics Inc.	Monoklonale hog-tcn1-antikörper und verfahren zu ihrer herstellung und ihre verwendung
US20240125807A1 (en) *	2020-12-18	2024-04-18	Chugai Seiyaku Kabushiki Kaisha	METHOD FOR MEASURING RELATIVE fu RATIO BY DYNAMIC ANALYSIS
CN113189252A (zh) *	2021-04-19	2021-07-30	中国医学科学院北京协和医院	一种总钴胺素和氰钴胺的检测方法及其检测试剂盒和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4273757A (en) *	1977-06-02	1981-06-16	Yissum Research Development Company	Determination of transcobalamins
US4332785A (en) *	1980-04-09	1982-06-01	University Patents, Inc.	Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
EP0069450B1 (de) *	1981-06-22	1985-04-10	TECHNICON INSTRUMENTS CORPORATION (a New York corporation)	Markierte Vitamin-B12-Derivate, ihre Herstellung und Verwendung
US4680273A (en) *	1985-07-29	1987-07-14	Victor Herbert	Assay for vitamin B12 deficiency
US5457055A (en) *	1986-11-20	1995-10-10	The University Of Colorado Foundation	Diagnostic method for cobalamin deficiency
US5374560A (en) *	1989-04-03	1994-12-20	The University Of Colorado, Inc.	Method for screening and distinguishing between cobalamin and folic acid deficiency based on assay for cystathionine and 2-methylcitric acid
DE3900650A1 (de) *	1989-01-11	1990-07-12	Boehringer Mannheim Gmbh	Vitamin-b12-bestimmung
US5506109A (en)	1989-06-26	1996-04-09	Bayer Corporation	Vitamin B12 assay
US5310656A (en)	1989-06-26	1994-05-10	Tritech Partners	Vitamin B12 assay
WO1991000519A1 (en) *	1989-06-26	1991-01-10	Triton Diagnostics, Inc.	Vitamin b12 assay
CA2135277C (en) *	1992-05-08	2001-04-24	Alton C. Morgan, Jr.	Anti-receptor agents to the vitamin b12/transcobalamin ii receptor
WO1998011900A2 (en) *	1996-09-18	1998-03-26	Sarill William J	Compositions containing cobalamin and amino acids

1998
- 1998-09-18 GB GBGB9820473.8A patent/GB9820473D0/en not_active Ceased
1999
- 1999-09-20 AT AT99947642T patent/ATE283490T1/de active
- 1999-09-20 BR BR9913770-4A patent/BR9913770A/pt not_active IP Right Cessation
- 1999-09-20 CN CNB2004100055424A patent/CN1322330C/zh not_active Expired - Fee Related
- 1999-09-20 DE DE69922225T patent/DE69922225T2/de not_active Expired - Lifetime
- 1999-09-20 WO PCT/GB1999/003127 patent/WO2000017659A1/en not_active Ceased
- 1999-09-20 HU HU0103532A patent/HU228077B1/hu not_active IP Right Cessation
- 1999-09-20 ES ES99947642T patent/ES2234299T3/es not_active Expired - Lifetime
- 1999-09-20 DK DK04009702T patent/DK1443328T3/da active
- 1999-09-20 KR KR1020017003485A patent/KR100781014B1/ko not_active Expired - Lifetime
- 1999-09-20 NZ NZ510766A patent/NZ510766A/en not_active IP Right Cessation
- 1999-09-20 AU AU61026/99A patent/AU761498B2/en not_active Ceased
- 1999-09-20 JP JP2000571269A patent/JP4394285B2/ja not_active Expired - Lifetime
- 1999-09-20 CZ CZ20010975A patent/CZ298310B6/cs not_active IP Right Cessation
- 1999-09-20 ES ES04009702T patent/ES2287607T3/es not_active Expired - Lifetime
- 1999-09-20 PL PL382436A patent/PL201360B1/pl unknown
- 1999-09-20 DE DE69936154T patent/DE69936154T2/de not_active Expired - Lifetime
- 1999-09-20 KR KR1020047014817A patent/KR100646305B1/ko not_active Expired - Lifetime
- 1999-09-20 PT PT99947642T patent/PT1114323E/pt unknown
- 1999-09-20 CA CA002344193A patent/CA2344193C/en not_active Expired - Lifetime
- 1999-09-20 CN CNB998110396A patent/CN1148580C/zh not_active Expired - Fee Related
- 1999-09-20 EP EP99947642A patent/EP1114323B1/de not_active Expired - Lifetime
- 1999-09-20 EP EP04009702A patent/EP1443328B1/de not_active Expired - Lifetime
- 1999-09-20 MX MXPA01002591A patent/MXPA01002591A/es not_active IP Right Cessation
- 1999-09-20 CZ CZ20023143A patent/CZ298381B6/cs not_active IP Right Cessation
- 1999-09-20 PL PL347104A patent/PL198095B1/pl unknown
- 1999-09-20 AT AT04009702T patent/ATE363076T1/de active
- 1999-09-20 PT PT04009702T patent/PT1443328E/pt unknown
2000
- 2000-10-04 US US09/679,043 patent/US7279283B1/en not_active Expired - Lifetime
2001
- 2001-03-16 NO NO20011353A patent/NO327771B1/no not_active IP Right Cessation
2007
- 2007-07-02 CY CY20071100864T patent/CY1106688T1/el unknown
2008
- 2008-08-21 NO NO20083610A patent/NO331074B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1148580C (zh)	2004-05-05
KR100646305B1 (ko)	2006-11-23
KR100781014B1 (ko)	2007-11-29
PL201360B1 (pl)	2009-04-30
MXPA01002591A (es)	2002-04-08
DE69922225D1 (de)	2004-12-30
PL347104A1 (en)	2002-03-25
ATE363076T1 (de)	2007-06-15
CY1106688T1 (el)	2012-05-23
EP1443328A3 (de)	2004-10-20
CA2344193A1 (en)	2000-03-30
HU228077B1 (en)	2012-10-29
NO331074B1 (no)	2011-09-26
NO20011353L (no)	2001-05-11
EP1443328B1 (de)	2007-05-23
WO2000017659A1 (en)	2000-03-30
NZ510766A (en)	2003-07-25
DE69936154T2 (de)	2008-01-24
PT1114323E (pt)	2005-02-28
EP1443328A2 (de)	2004-08-04
CN1530659A (zh)	2004-09-22
PT1443328E (pt)	2007-06-11
HUP0103532A2 (en)	2002-01-28
DE69936154D1 (de)	2007-07-05
NO327771B1 (no)	2009-09-21
GB9820473D0 (en)	1998-11-11
KR20010079854A (ko)	2001-08-22
CZ2001975A3 (cs)	2001-11-14
AU761498B2 (en)	2003-06-05
CA2344193C (en)	2009-04-07
US7279283B1 (en)	2007-10-09
HUP0103532A3 (en)	2006-03-28
CN1324450A (zh)	2001-11-28
NO20083610L (no)	2001-05-11
CZ298381B6 (cs)	2007-09-12
JP4394285B2 (ja)	2010-01-06
CZ298310B6 (cs)	2007-08-22
JP2002525607A (ja)	2002-08-13
EP1114323A1 (de)	2001-07-11
CN1322330C (zh)	2007-06-20
ATE283490T1 (de)	2004-12-15
EP1114323B1 (de)	2004-11-24
AU6102699A (en)	2000-04-10
ES2287607T3 (es)	2007-12-16
BR9913770A (pt)	2001-06-05
NO20011353D0 (no)	2001-03-16
DE69922225T2 (de)	2005-04-14
PL198095B1 (pl)	2008-05-30
KR20040104529A (ko)	2004-12-10
ES2234299T3 (es)	2005-06-16

Publication	Publication Date	Title
NO20083610L (no)	2001-05-11	Cobalamin-maling
AU8058798A (en)	1998-12-21	Method and device for detecting or quantifying carbohydrate containing compounds
AU9066998A (en)	1999-02-16	Use of check surfaces for identifying disturbing samples in a detection procedure
DE69623458D1 (de)	2002-10-10	Einstufige immunochromatographische vorrichtung und verfahren zu ihrer verwendung
WO2003023057A3 (de)	2003-12-18	Verfahren und diagnose-kit zur selektionierung und/oder zum qualitativen und/oder quantitativen nachweis von zellen
DE69233674D1 (de)	2007-02-15	Homogenes Testsystem zur Bestimmung eines Analytes
EP1092979A3 (de)	2004-01-21	Durch kovalente Bindung von Molekülen an eine aktivierte Festphase herstellte Vorrichtungen
GB9804083D0 (en)	1998-04-22	Immunoassays
ES511797A0 (es)	1983-02-01	"metodo para ensayar reacciones antigeno-anticuerpo".
EP0617285A3 (en)	1995-09-20	Decreasing the hook-effect in immunoassays with carrier particles.
AU3059499A (en)	1999-10-18	Solid-phase method for antigen and antibody determinations in bloodgroup serology, and test kit
CA2285219A1 (en)	1998-10-08	Detection of low level analytes in samples
AU2375695A (en)	1995-11-29	Solid-phase filtration method for antigen and antibody assays in bloodgroup serology, and test kit
DK0797097T3 (da)	2002-04-15	Partikel-immunoassay med kompakt matrix
NZ511217A (en)	2002-12-20	Method for measuring cellular adhesion
CA2417161A1 (en)	2002-01-31	Method for immuno-detection of epitopes
MY106963A (en)	1995-08-30	Agglutination assay.
ATE208040T1 (de)	2001-11-15	Immunoassay-reagenzien, testsätze und verfahren
CA2123069A1 (en)	1994-11-20	Immunoassay for analytes in samples using alkylating agents
DE59910326D1 (de)	2004-09-30	Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
EP0757251A3 (de)	1999-07-07	Bewertung der Veränderung von Knochen-Mineraldichten und Diagnose von Osteoporose
EP0518827A3 (en)	1993-01-20	System (reagent and instrument) for the automatic determination of the presence of total or allergen specific immunoglobulin e, or other molecules in aqueous samples