DK1448559T3 - 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolodin-2,4-dionbenzensulfat; fremgangsmåde til dets fremstilling; polymorf i, II og III deraf; og dets anvendelse som farmaceutisk aktiv bestenddel - Google Patents

5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolodin-2,4-dionbenzensulfat; fremgangsmåde til dets fremstilling; polymorf i, II og III deraf; og dets anvendelse som farmaceutisk aktiv bestenddel

Info

Publication number: DK1448559T3
Authority: DK; Denmark
Prior art keywords: pyridyl; ethoxy; benzyl; amino; methyl
Prior art date: 2001-11-21

Application number

DK02779711T

Other languages

English (en)

Inventor

Andrew Simon Craig

Michael John Millan

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-21

Filing date

2002-11-21

Publication date

2007-04-30

2001-11-21 Priority claimed from GB0127936A external-priority patent/GB0127936D0/en

2001-11-21 Priority claimed from GB0127937A external-priority patent/GB0127937D0/en

2001-11-21 Priority claimed from GB0127935A external-priority patent/GB0127935D0/en

2001-11-21 Priority claimed from GB0127934A external-priority patent/GB0127934D0/en

2002-11-21 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2007-04-30 Application granted granted Critical

2007-04-30 Publication of DK1448559T3 publication Critical patent/DK1448559T3/da

Links

-1 4- (2- (N-methyl-N- (2-pyridyl) amino) ethoxy) benzyl Chemical group 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK02779711T 2001-11-21 2002-11-21 5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolodin-2,4-dionbenzensulfat; fremgangsmåde til dets fremstilling; polymorf i, II og III deraf; og dets anvendelse som farmaceutisk aktiv bestenddel DK1448559T3 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
GB0127936A GB0127936D0 (en)	2001-11-21	2001-11-21	Novel compounds
GB0127937A GB0127937D0 (en)	2001-11-21	2001-11-21	Novel compounds
GB0127935A GB0127935D0 (en)	2001-11-21	2001-11-21	Novel compounds
GB0127934A GB0127934D0 (en)	2001-11-21	2001-11-21	Novel compounds
PCT/GB2002/005232 WO2003045946A1 (en)	2001-11-21	2002-11-21	5-(4-(2-(n-methyl-n-(2-pyridil) amino) ethoxy) benzyl) thiazolidine-2, 4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient

Publications (1)

Publication Number	Publication Date
DK1448559T3 true DK1448559T3 (da)	2007-04-30

Family

ID=27448006

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02779711T DK1448559T3 (da)	2001-11-21	2002-11-21	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolodin-2,4-dionbenzensulfat; fremgangsmåde til dets fremstilling; polymorf i, II og III deraf; og dets anvendelse som farmaceutisk aktiv bestenddel

Country Status (13)

Country	Link
EP (1)	EP1448559B1 (da)
JP (1)	JP2005513038A (da)
KR (1)	KR20040062963A (da)
CN (1)	CN100390170C (da)
AT (1)	ATE349444T1 (da)
AU (1)	AU2002343050A1 (da)
CY (1)	CY1106397T1 (da)
DE (1)	DE60217168T2 (da)
DK (1)	DK1448559T3 (da)
ES (1)	ES2278977T3 (da)
PT (1)	PT1448559E (da)
SI (1)	SI1448559T1 (da)
WO (1)	WO2003045946A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102005034406A1 (de) *	2005-07-22	2007-02-01	Ratiopharm Gmbh	Neue Salze von Rosiglitazon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
GB9909041D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
GB9909075D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
GB0006133D0 (en) *	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
GB0021784D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
ATE337313T1 (de) *	2000-12-22	2006-09-15	Smithkline Beecham Plc	5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy)benzyl)thiazolidin-2,4-dion mesylatsalz

2002
- 2002-11-21 WO PCT/GB2002/005232 patent/WO2003045946A1/en not_active Ceased
- 2002-11-21 CN CNB028267699A patent/CN100390170C/zh not_active Expired - Fee Related
- 2002-11-21 JP JP2003547396A patent/JP2005513038A/ja active Pending
- 2002-11-21 KR KR10-2004-7007678A patent/KR20040062963A/ko not_active Ceased
- 2002-11-21 EP EP02779711A patent/EP1448559B1/en not_active Expired - Lifetime
- 2002-11-21 PT PT02779711T patent/PT1448559E/pt unknown
- 2002-11-21 ES ES02779711T patent/ES2278977T3/es not_active Expired - Lifetime
- 2002-11-21 AT AT02779711T patent/ATE349444T1/de not_active IP Right Cessation
- 2002-11-21 SI SI200230499T patent/SI1448559T1/sl unknown
- 2002-11-21 DE DE60217168T patent/DE60217168T2/de not_active Expired - Fee Related
- 2002-11-21 DK DK02779711T patent/DK1448559T3/da active
- 2002-11-21 AU AU2002343050A patent/AU2002343050A1/en not_active Abandoned
2007
- 2007-03-16 CY CY20071100381T patent/CY1106397T1/el unknown

Also Published As

Publication number	Publication date
AU2002343050A1 (en)	2003-06-10
ATE349444T1 (de)	2007-01-15
SI1448559T1 (sl)	2007-06-30
WO2003045946A1 (en)	2003-06-05
CN1612875A (zh)	2005-05-04
CN100390170C (zh)	2008-05-28
PT1448559E (pt)	2007-03-30
DE60217168T2 (de)	2007-10-04
ES2278977T3 (es)	2007-08-16
DE60217168D1 (de)	2007-02-08
HK1068884A1 (en)	2005-05-06
KR20040062963A (ko)	2004-07-09
EP1448559B1 (en)	2006-12-27
JP2005513038A (ja)	2005-05-12
EP1448559A1 (en)	2004-08-25
CY1106397T1 (el)	2011-10-12

Publication	Publication Date	Title
DK1446404T3 (da)	2006-10-09	Rosiglitazonedisylater og deres anvendelse som antidiabetika
DK1349855T3 (da)	2006-12-27	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidin-2,4-dionmesylatsalt
DK1315724T3 (da)	2006-02-20	Thiazolidindionderivat og dets anvendelse som antidiabetikum
EA200300234A1 (ru)	2003-06-26	Тартратные соли производного тиазолидиндиона
DK1448559T3 (da)	2007-04-30	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolodin-2,4-dionbenzensulfat; fremgangsmåde til dets fremstilling; polymorf i, II og III deraf; og dets anvendelse som farmaceutisk aktiv bestenddel
AP1715A (en)	2007-02-28	The hydrochloride salt of 5-[ 4 -[2 -(n-methyl-n- (2-pyridyl) amino) ethoxy]benzyl]thiazolidine -2,4-dione
DK1315721T3 (da)	2007-02-19	Et Thiazolidindionderivat og dets anvendelse som et antidiabetisk middel
NO20076517L (no)	2003-04-29	Natriumsalter av 5-[4-[2-(N-metyl-N-(2-pyridyl)amino)etoksyl]benzyl]tiazolidin-2,4-dion
AP1785A (en)	2007-10-04	Tartrate salt of thiazolidinedione derivative.
NO20075507L (no)	2003-05-27	Tiazolidindionderivater og deres anvendelse som antidiabetiske midler
MXPA02012100A (es)	2003-04-25	Sal de tiazodilindiona para el tratamiento de la diabetes mellitus.
AP2002002684A0 (en)	2002-12-31	5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2- pyridyl) amino)ethoxy) benzyl) thiazolidine-2, 4-dione hydriodide as pharmaceutical.5-(4-(2-(n-methyl-n-(2-pyridyl) amino) ethoxy)benzyl) thiazolidine-2,4-dione hydriodide as pharmaceutical
EA200300232A1 (ru)	2003-06-26	Тартратные соли производного тиазолидиндиона