DK1468009T3 - Peptidoprensning - Google Patents

Peptidoprensning

Info

Publication number: DK1468009T3
Authority: DK; Denmark
Prior art keywords: sub; solvent; water; mixture; decapeptide
Prior art date: 2001-12-29

Application number

DK02783479.5T

Other languages

Danish (da)

English (en)

Inventor

Jon H Rasmussen

Palle H Rasmussen

Original Assignee

Carlbiotech Ltd As

Jon H Rasmussen

Palle H Rasmussen

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-29

Filing date

2002-12-23

Publication date

2010-04-06

2002-12-23 Application filed by Carlbiotech Ltd As, Jon H Rasmussen, Palle H Rasmussen filed Critical Carlbiotech Ltd As

2010-04-06 Application granted granted Critical

2010-04-06 Publication of DK1468009T3 publication Critical patent/DK1468009T3/da

Links

108090000765 processed proteins & peptides Proteins 0.000 title 1
238000000746 purification Methods 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
239000002904 solvent Substances 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 abstract 2
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
UAEPNZWRGJTJPN-UHFFFAOYSA-N methylcyclohexane Chemical compound CC1CCCCC1 UAEPNZWRGJTJPN-UHFFFAOYSA-N 0.000 abstract 2
238000001556 precipitation Methods 0.000 abstract 2
239000011877 solvent mixture Substances 0.000 abstract 2
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001735 carboxylic acids Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004090 dissolution Methods 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
GYNNXHKOJHMOHS-UHFFFAOYSA-N methyl-cycloheptane Natural products CC1CCCCCC1 GYNNXHKOJHMOHS-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
235000019260 propionic acid Nutrition 0.000 abstract 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK02783479.5T 2001-12-29 2002-12-23 Peptidoprensning DK1468009T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0104462A SE0104462D0 (sv)	2001-12-29	2001-12-29	Peptide purifcation (Peptidrening)
PCT/IB2002/005581 WO2003055900A1 (en)	2001-12-29	2002-12-23	Peptide purification

Publications (1)

Publication Number	Publication Date
DK1468009T3 true DK1468009T3 (da)	2010-04-06

Family

ID=20286556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02783479.5T DK1468009T3 (da)	2001-12-29	2002-12-23	Peptidoprensning

Country Status (18)

Country	Link
US (1)	US7057014B2 (2)
EP (1)	EP1468009B1 (2)
JP (1)	JP4378173B2 (2)
KR (1)	KR100880828B1 (2)
CN (1)	CN1272341C (2)
AT (1)	ATE449784T1 (2)
AU (1)	AU2002347550B2 (2)
CA (1)	CA2471717C (2)
DE (1)	DE60234535D1 (2)
DK (1)	DK1468009T3 (2)
ES (1)	ES2350880T3 (2)
IL (2)	IL162789A0 (2)
NO (1)	NO329024B1 (2)
NZ (1)	NZ534151A (2)
RU (1)	RU2303040C2 (2)
SE (1)	SE0104462D0 (2)
WO (1)	WO2003055900A1 (2)
ZA (1)	ZA200405135B (2)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1359722A1 (en) *	2002-03-27	2003-11-05	BRITISH TELECOMMUNICATIONS public limited company	Data streaming system and method
MX2007008781A (es)	2005-01-21	2007-09-11	Astex Therapeutics Ltd	Compuestos farmaceuticos.
WO2008044041A1 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical combinations
JP5528807B2 (ja)	2006-10-12	2014-06-25	アステックス、セラピューティックス、リミテッド	複合薬剤
EP2062909A1 (en) *	2007-11-21	2009-05-27	SOLVAY (Société Anonyme)	Peptide production and purification process
US9051349B2 (en)	2007-11-21	2015-06-09	Alba Therapeutics Corporation	Larazotide acetate compositions
CN102027005A (zh) *	2008-05-15	2011-04-20	诺沃-诺迪斯克有限公司	通过固相合成制备的肽的纯化
WO2010115916A1 (en) *	2009-04-10	2010-10-14	F. Hoffmann-La Roche Ag	Process for isolating therapeutic peptide
WO2015012904A2 (en)	2012-12-13	2015-01-29	Immunomedics, Inc.	Antibody-sn-38 immunoconjugates with a cl2a linker
US9931417B2 (en)	2012-12-13	2018-04-03	Immunomedics, Inc.	Antibody-SN-38 immunoconjugates with a CL2A linker
SI2900277T1 (sl)	2012-12-13	2022-05-31	Immunomedics, Inc.	Odmerki imunokonjugatov protiteles in SN-38 za boljšo učinkovitost in zmanjšano toksičnost
AU2014293670B2 (en) *	2013-07-23	2019-08-01	Immunomedics, Inc.	Antibody-SN-38 immunoconjugates with a CL2A linker
JP7379795B2 (ja)	2016-04-27	2023-11-15	イミューノメディクス、インコーポレイテッド	チェックポイント阻害薬に再発／耐性を示す腫瘍を治療するための抗Ｔｒｏｐ－２－ＳＮ－３８抗体薬物複合体の効果
US10918734B2 (en)	2017-03-27	2021-02-16	Immunomedics, Inc.	Treatment of high Trop-2 expressing triple negative breast cancer (TNBC) with sacituzumab govitecan (IMMU-132) overcomes homologous recombination repair (HRR) rescue mediated by Rad51
WO2018187074A1 (en)	2017-04-03	2018-10-11	Immunomedics, Inc.	Subcutaneous administration of antibody-drug conjugates for cancer therapy
CN113952944B (zh) *	2021-12-23	2022-03-29	浙江湃肽生物有限公司深圳分公司	一种纯化九肽-1的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8317697D0 (en) *	1983-06-29	1983-08-03	Shell Int Research	Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents
DE4001238A1 (de) *	1990-01-18	1991-07-25	Basf Ag	Verfahren zur anreicherung bzw. reinigung von biomolekuelen
DE19544212A1 (de) *	1995-11-28	1997-06-05	Asta Medica Ag	Neue LH-RH-Antagonisten mit verbesserter Wirkung
DE19813849A1 (de) *	1998-03-27	1999-09-30	Degussa	Verfahren zur einstufigen Umsalzung und Aufreinigung von Oligopeptiden
EP0998940A1 (en)	1998-09-30	2000-05-10	Laboratoire Theramex	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues
DE19911771B4 (de) *	1999-03-17	2006-03-30	Zentaris Gmbh	LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung

2001
- 2001-12-29 SE SE0104462A patent/SE0104462D0/xx unknown
2002
- 2002-12-23 IL IL16278902A patent/IL162789A0/xx unknown
- 2002-12-23 NZ NZ534151A patent/NZ534151A/en not_active IP Right Cessation
- 2002-12-23 RU RU2004119965/04A patent/RU2303040C2/ru not_active IP Right Cessation
- 2002-12-23 DE DE60234535T patent/DE60234535D1/de not_active Expired - Lifetime
- 2002-12-23 JP JP2003556430A patent/JP4378173B2/ja not_active Expired - Fee Related
- 2002-12-23 EP EP02783479A patent/EP1468009B1/en not_active Expired - Lifetime
- 2002-12-23 ES ES02783479T patent/ES2350880T3/es not_active Expired - Lifetime
- 2002-12-23 CN CNB028283481A patent/CN1272341C/zh not_active Expired - Fee Related
- 2002-12-23 CA CA2471717A patent/CA2471717C/en not_active Expired - Fee Related
- 2002-12-23 WO PCT/IB2002/005581 patent/WO2003055900A1/en not_active Ceased
- 2002-12-23 KR KR1020047010363A patent/KR100880828B1/ko not_active Expired - Fee Related
- 2002-12-23 US US10/500,302 patent/US7057014B2/en not_active Expired - Fee Related
- 2002-12-23 AT AT02783479T patent/ATE449784T1/de not_active IP Right Cessation
- 2002-12-23 DK DK02783479.5T patent/DK1468009T3/da active
- 2002-12-23 AU AU2002347550A patent/AU2002347550B2/en not_active Ceased
2004
- 2004-06-28 ZA ZA2004/05135A patent/ZA200405135B/en unknown
- 2004-06-29 IL IL162789A patent/IL162789A/en not_active IP Right Cessation
- 2004-07-16 NO NO20043046A patent/NO329024B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA200405135B (en)	2005-08-31
HK1076112A1 (en)	2006-01-06
ES2350880T3 (es)	2011-01-27
RU2004119965A (ru)	2006-01-10
IL162789A (en)	2010-04-29
KR100880828B1 (ko)	2009-01-30
US7057014B2 (en)	2006-06-06
NO20043046L (no)	2004-08-30
SE0104462D0 (sv)	2001-12-29
ATE449784T1 (de)	2009-12-15
EP1468009B1 (en)	2009-11-25
CA2471717A1 (en)	2003-07-10
NZ534151A (en)	2007-05-31
RU2303040C2 (ru)	2007-07-20
AU2002347550B2 (en)	2008-01-03
JP2005515217A (ja)	2005-05-26
IL162789A0 (en)	2005-11-20
AU2002347550A1 (en)	2003-07-15
JP4378173B2 (ja)	2009-12-02
DE60234535D1 (de)	2010-01-07
US20060014694A1 (en)	2006-01-19
KR20040090966A (ko)	2004-10-27
WO2003055900A1 (en)	2003-07-10
CN1625561A (zh)	2005-06-08
NO329024B1 (no)	2010-08-02
CA2471717C (en)	2013-06-18
EP1468009A1 (en)	2004-10-20
CN1272341C (zh)	2006-08-30

Publication	Publication Date	Title
DK1468009T3 (da)	2010-04-06	Peptidoprensning
JP2004506738A5 (2)	2005-03-03
MY142836A (en)	2011-01-14	Self-extinguishing catalyst composition with monocarboxylic acid ester internal donor and propylene polymerization process
ATE296357T1 (de)	2005-06-15	Verfahren zur herstellung von hochreinen hmg-coa reductase inhibitoren
SI1515962T1 (sl)	2007-04-30	Postopek za pripravo dioksan estrov ocetne kisline
DK0925065T3 (da)	2005-10-17	Vandblandbare erythromycinsammensætninger
CS212284B2 (en)	1982-03-26	Method of making the 1,1-dioxides of the acetoxymethylpenam derivatives
AU5421299A (en)	2000-03-14	Substituted cinnamic acids and cinnamic acid esters
ATE258911T1 (de)	2004-02-15	Verfahren zur herstellung von alkoxyzimtsäureester
Tabushi et al.	1983	Photoreduction of keto carboxylic acid derivatives to oxyacid derivatives catalyzed by ZnTPPS [zinc tetraphenylporphyrintetrasulfonate]-quinolinium-3-carboxamide-CTAB micelle
CA2573129A1 (en)	2006-01-26	Process for preparing levofloxacin or its hydrate
KR890014575A (ko)	1989-10-24	α-L-아스파르틸-L-페닐알라닌 메틸에스테르의 분리방법
ATE437858T1 (de)	2009-08-15	Verfahren zur herstellung eines hochreinen 3,5- dihydroxy-6-heptensäurederivats
CA1233171A (en)	1988-02-23	Process for the preparation of 6,6- dibromopenicillanic acid 1,1-dioxide
RU2000114008A (ru)	2002-04-27	Способ выделения кислот из углеводородных смесей
DK0727408T3 (da)	1999-08-16	Fremgangsmåde til udnyttelse på esterform af den i de lette fraktioner fra oprensning af acrylsyre indeholdte eddikesyre
KR960041184A (ko)	1996-12-19	7-[(2-카르보알콕시-1-메틸에테닐)아미노]-3-히드록시메틸-3-세펨-4-카르복시산의 제조방법 및 이의 중간체
NO920158D0 (no)	1992-01-13	Fremgangsmaate for oekning av forholdet for alfa til beta ien aspartam-koblingsreaksjon
NO20013528L (no)	2001-07-17	Fremgangsmate for reduksjon av 3-dimetylamino-2- fenylpropionsyre-etylester-innhold i losninger av 2-dimetylamino-1-fenyl-3-cykloheksen-1-karboksylsyre-etylester
RU95120710A (ru)	1997-12-20	Способ герметизации трубопровода
TH63268A (th)	2004-08-09	การนำอะคริลิก แอซิดกลับคืนมา โดยใช้ เอธิล อะคริเลต และตัวทำละลายร่วม ที่เลือกมา
JPS53147063A (en)	1978-12-21	Preparation of alpha-acyloxythienyl acetic acids