DK1471892T3 - Transdermalt terapeutisk system til parkinsons sygdom, der inducerer höje rotigotinplasmaniveauer - Google Patents

Transdermalt terapeutisk system til parkinsons sygdom, der inducerer höje rotigotinplasmaniveauer

Info

Publication number: DK1471892T3
Authority: DK; Denmark
Prior art keywords: parkinson; therapeutic system; transdermal therapeutic; disease; plasma levels
Prior art date: 2001-05-08

Application number

DK02740569T

Other languages

English (en)

Inventor

Thomas Lauterbach

Dietrich Wilhelm Schacht

Hans-Michael Wolff

Walter Mueller

Original Assignee

Sanol Arznei Schwarz Gmbh

Lohmann Therapie Syst Lts

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-08

Filing date

2002-05-06

Publication date

2009-12-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8177356&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1471892(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-05-06 Application filed by Sanol Arznei Schwarz Gmbh, Lohmann Therapie Syst Lts filed Critical Sanol Arznei Schwarz Gmbh

2009-12-07 Application granted granted Critical

2009-12-07 Publication of DK1471892T3 publication Critical patent/DK1471892T3/da

Links

KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 3
229960003179 rotigotine Drugs 0.000 title abstract 3
230000036470 plasma concentration Effects 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title abstract 2
208000018737 Parkinson disease Diseases 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 1
230000000648 anti-parkinson Effects 0.000 abstract 1
239000000939 antiparkinson agent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229920001296 polysiloxane Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Optical Elements Other Than Lenses (AREA)
Radiation-Therapy Devices (AREA)

DK02740569T 2001-05-08 2002-05-06 Transdermalt terapeutisk system til parkinsons sygdom, der inducerer höje rotigotinplasmaniveauer DK1471892T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01111109A EP1256339B1 (en)	2001-05-08	2001-05-08	Transdermal therapeutic system for Parkinson's disease inducing high plasma levels of rotigotine
PCT/EP2002/004976 WO2002089778A2 (en)	2001-05-08	2002-05-06	Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine

Publications (1)

Publication Number	Publication Date
DK1471892T3 true DK1471892T3 (da)	2009-12-07

Family

ID=8177356

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK01111109T DK1256339T3 (da)	2001-05-08	2001-05-08	Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom
DK02740569T DK1471892T3 (da)	2001-05-08	2002-05-06	Transdermalt terapeutisk system til parkinsons sygdom, der inducerer höje rotigotinplasmaniveauer

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK01111109T DK1256339T3 (da)	2001-05-08	2001-05-08	Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom

Country Status (15)

Country	Link
EP (3)	EP1256339B1 (da)
JP (2)	JP5026656B2 (da)
KR (1)	KR100974974B1 (da)
CN (2)	CN1606435A (da)
AT (2)	ATE251901T1 (da)
CY (1)	CY1109861T1 (da)
DE (2)	DE60100994T2 (da)
DK (2)	DK1256339T3 (da)
ES (2)	ES2204780T3 (da)
HK (1)	HK1049444B (da)
HU (1)	HU229350B1 (da)
PT (2)	PT1256339E (da)
RU (1)	RU2272625C2 (da)
WO (1)	WO2002089778A2 (da)
ZA (1)	ZA200209982B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10041478A1 (de)	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
ATE246919T1 (de) *	2001-05-08	2003-08-15	Sanol Arznei Schwarz Gmbh	Verbessertes transdermales therapeutisches system zur behandlung von morbus parkinson
DE10220230A1 (de) *	2002-05-06	2003-11-27	Sanol Arznei Schwarz Gmbh	Verwendung von Rotigotine zur Behandlung des Restless Leg Syndroms
DE10261696A1 (de) *	2002-12-30	2004-07-15	Schwarz Pharma Ag	Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
DE10334187A1 (de) *	2003-07-26	2005-03-03	Schwarz Pharma Ag	Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) *	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
DE10338174A1 (de)	2003-08-20	2005-03-24	Lts Lohmann Therapie-Systeme Ag	Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
DE10359528A1 (de)	2003-12-18	2005-07-28	Schwarz Pharma Ag	(S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
EP1547592A1 (en)	2003-12-23	2005-06-29	Schwarz Pharma Ag	Intranasal formulation of rotigotine
DE10361258A1 (de) *	2003-12-24	2005-07-28	Schwarz Pharma Ag	Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
DE10361259A1 (de) *	2003-12-24	2005-07-28	Schwarz Pharma Ag	Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes
DE102004014841B4 (de) *	2004-03-24	2006-07-06	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
JP2008514376A (ja) *	2004-09-29	2008-05-08	シュウォーツファーマインコーポレイテッド	パーキンソン病のための経皮治療システム
CN101147739B (zh)	2007-07-06	2010-12-08	北京康倍得医药技术开发有限公司	含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂
DE102008060203A1 (de)	2008-12-07	2010-06-10	Dietrich Wilhelm Schacht	Wirkstoffstabilisierende flächenförmige Vorrichtung
EP2201941A1 (de)	2008-12-29	2010-06-30	UCB Pharma GmbH	Pflaster-Herstellungstechnologie
WO2011048491A2 (en) *	2009-10-19	2011-04-28	Actavis Group Ptc Ehf	Amorphous rotigotine co-precipitates
LT3257504T (lt)	2009-12-22	2024-08-26	UCB Biopharma SRL	Polivinilpirolidonas, skirtas nekristalinės formos kietos rotigotino dispersijos stabilizavimui
TW201431570A (zh) *	2012-11-22	2014-08-16	Ucb Pharma Gmbh	用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
JP6726096B2 (ja)	2013-07-03	2020-07-22	エルテーエスローマンテラピー−システメアーゲー	電子部品を有する経皮治療システム
US11752110B2 (en)	2014-05-20	2023-09-12	Lts Lohmann Therapie-Systeme Ag	Transdermal delivery system including an interface mediator
CN106456566B (zh)	2014-05-20	2020-06-16	Lts勒曼治疗系统股份公司	含罗替戈汀的经皮递送系统
CA2948219C (en)	2014-05-20	2023-04-04	Lts Lohmann Therapie-Systeme Ag	Method for adjusting the release of active agent in a transdermal delivery system
KR102364378B1 (ko) *	2014-05-21	2022-02-16	에스케이케미칼 주식회사	안정성을 향상시킨 로티고틴 함유 경피흡수제제
DE102014114282A1 (de)	2014-10-01	2016-04-07	Neuraxpharm Arzneimittel Gmbh	Transdermales therapeutisches System mit Rotigotin zur Behandlung von Morbus Parkinson
EP3563852B1 (en)	2016-12-28	2025-04-02	Hisamitsu Pharmaceutical Co., Inc.	Butorphanol-containing patch
DE102018120506A1 (de) *	2017-10-20	2019-04-25	Amw Gmbh	Stabilisiertes transdermales Darreichungssystem
ES2966170T3 (es)	2020-01-24	2024-04-18	Luye Pharma Switzerland Ag	Sistema terapéutico transdérmico que comprende rotigotina y al menos un adhesivo de silicona no resistente a las aminas

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Publication number	Priority date	Publication date	Assignee	Title
JPH0751515B2 (ja) *	1986-09-10	1995-06-05	明治製菓株式会社	経皮吸収製剤
US5474783A (en) *	1988-03-04	1995-12-12	Noven Pharmaceuticals, Inc.	Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5656286A (en) *	1988-03-04	1997-08-12	Noven Pharmaceuticals, Inc.	Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5989586A (en) *	1992-10-05	1999-11-23	Cygnus, Inc.	Two-phase matrix for sustained release drug delivery device
FR2732223B1 (fr) *	1995-03-30	1997-06-13	Sanofi Sa	Composition pharmaceutique pour administration transdermique
DE19814084B4 (de) *	1998-03-30	2005-12-22	Lts Lohmann Therapie-Systeme Ag	D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19940238A1 (de) *	1999-08-25	2001-03-01	Lohmann Therapie Syst Lts	Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten

2001
- 2001-05-08 EP EP01111109A patent/EP1256339B1/en not_active Expired - Lifetime
- 2001-05-08 PT PT01111109T patent/PT1256339E/pt unknown
- 2001-05-08 DE DE60100994T patent/DE60100994T2/de not_active Expired - Lifetime
- 2001-05-08 DK DK01111109T patent/DK1256339T3/da active
- 2001-05-08 ES ES01111109T patent/ES2204780T3/es not_active Expired - Lifetime
- 2001-05-08 AT AT01111109T patent/ATE251901T1/de active
- 2001-05-08 EP EP03013353A patent/EP1344522A1/en not_active Withdrawn
2002
- 2002-05-06 AT AT02740569T patent/ATE444061T1/de active
- 2002-05-06 EP EP02740569A patent/EP1471892B1/en not_active Revoked
- 2002-05-06 CN CNA028015401A patent/CN1606435A/zh active Pending
- 2002-05-06 JP JP2002586915A patent/JP5026656B2/ja not_active Expired - Lifetime
- 2002-05-06 ES ES02740569T patent/ES2331787T3/es not_active Expired - Lifetime
- 2002-05-06 RU RU2003133217/15A patent/RU2272625C2/ru active IP Right Revival
- 2002-05-06 KR KR1020037000143A patent/KR100974974B1/ko not_active Expired - Lifetime
- 2002-05-06 WO PCT/EP2002/004976 patent/WO2002089778A2/en not_active Ceased
- 2002-05-06 DE DE60233898T patent/DE60233898D1/de not_active Expired - Lifetime
- 2002-05-06 PT PT02740569T patent/PT1471892E/pt unknown
- 2002-05-06 DK DK02740569T patent/DK1471892T3/da active
- 2002-05-06 HU HU0500525A patent/HU229350B1/hu unknown
- 2002-05-06 CN CN2011100516651A patent/CN102172351B/zh not_active Expired - Lifetime
- 2002-12-10 ZA ZA200209982A patent/ZA200209982B/xx unknown
2003
- 2003-03-04 HK HK03101599.0A patent/HK1049444B/en unknown
2009
- 2009-11-05 CY CY20091101150T patent/CY1109861T1/el unknown
2010
- 2010-01-07 JP JP2010002209A patent/JP2010106037A/ja active Pending

Also Published As

Publication number	Publication date
HK1049444A1 (en)	2003-05-16
EP1471892B1 (en)	2009-09-30
KR100974974B1 (ko)	2010-08-09
EP1344522A1 (en)	2003-09-17
EP1471892A2 (en)	2004-11-03
ATE444061T1 (de)	2009-10-15
PT1471892E (pt)	2009-12-23
ZA200209982B (en)	2003-03-24
DE60233898D1 (de)	2009-11-12
DK1256339T3 (da)	2004-02-09
CN1606435A (zh)	2005-04-13
WO2002089778A2 (en)	2002-11-14
ES2204780T3 (es)	2004-05-01
PT1256339E (pt)	2004-02-27
HK1049444B (en)	2004-03-19
KR20030016373A (ko)	2003-02-26
JP2010106037A (ja)	2010-05-13
EP1256339B1 (en)	2003-10-15
DE60100994D1 (de)	2003-11-20
HU229350B1 (en)	2013-11-28
JP5026656B2 (ja)	2012-09-12
JP2004536054A (ja)	2004-12-02
EP1256339A1 (en)	2002-11-13
WO2002089778A3 (en)	2004-08-19
CN102172351B (zh)	2013-07-17
RU2003133217A (ru)	2005-04-20
CY1109861T1 (el)	2014-09-10
DE60100994T2 (de)	2004-07-22
ES2331787T3 (es)	2010-01-15
RU2272625C2 (ru)	2006-03-27
CN102172351A (zh)	2011-09-07
ATE251901T1 (de)	2003-11-15
HUP0500525A2 (hu)	2005-09-28

Publication	Publication Date	Title
DK1471892T3 (da)	2009-12-07	Transdermalt terapeutisk system til parkinsons sygdom, der inducerer höje rotigotinplasmaniveauer
PT1256340E (pt)	2003-12-31	Sistema terapeutico transdermico aperfeicoado para o tratamento da doenca de parkinson
BR0312573A (pt)	2005-04-26	Derivados de fenil-[4-(3-fenil-1h-pirazol-4-il)-pirimidin-2-il]-amina
DE60121301D1 (de)	2006-08-17	Flibanserin zur Behandlung extrapyramidaler Bewegungsstörungen
HUP0102728A2 (hu)	2002-03-28	Módszerek és transzdermális készítmények fájdalom csillapítására
PT1383752E (pt)	2005-11-30	3-piperidinopropiofenonas deuteradas assim como farmacos contendo estes compostos
MXPA05003253A (es)	2005-06-08	Nuevos derivados de pirimidinamida y el uso de los mismos.
DE60211139D1 (de)	2006-06-08	Feste arzneizusammensetzung enthaltend 4'-cyano-trifluoro-3-(4-fluorophenylsulphonyl) -2-hydroxy-2-methylpropiono- m toluidide und pvp
DK1311248T3 (da)	2007-08-20	Transdermalt terapeutisk system til behandling af Restless Legs syndromet
ATE262893T1 (de)	2004-04-15	Darreichungsformen zur behandlung von oralen mykosen
ATE464878T1 (de)	2010-05-15	Pharmazeutische zusammensetzung zur nasalen anwendung von fentanyl
PL368040A1 (en)	2005-03-21	Substituted 4-aminocyclohexanol derivatives
SE0203817D0 (sv)	2002-12-20	New composition
MXPA05012826A (es)	2006-02-13	Compuestos utiles en la terapia de la enfermedad de alzheimer y formulaciones que los contienen.
WO2006039532A3 (en)	2006-07-13	Transdermal therapeutic system for parkinson’s disease
TR200301916T4 (tr)	2004-01-21	Rotigotinin yüksek plazma seviyelerini kapsayan parkinson hastalığına yönelik transdermal terapötik sistem.
ECSP961863A (es)	1997-12-09	Compuesto activo farmacologicamente